Anahí Binagui-Casas

@abinagui.bsky.social

DevBio in Val Wilson's Lab @edinuni-irr.bsky.social - Embryos, tails, cell fate decisions and a soft spot for all things endothelial | Prev @geneticsub.bsky.social #SinCienciaNoHayFuturo #diversityinSTEM

Frank Grosveld, born in 1948, passed away last Friday. He was a colossal scientist in the transcriptional control of gene expression during development and helped us understand the complex regulation of beta-globin genes. His work will remain as a reference. May he rest in peace.

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🚨Can embryos regenerate their tails? A question I had. With support from @biologists.bsky.social, Val Wilson, Elly Tanaka and Wouter🙏, I visited Vienna to start by cutting axolotl embryo tail buds. The answer: Not always!😮...Sparking a fun and exciting collaboration that is only the beginning.

Wouter Masselink@woutermasselink.bsky.social · 2mo ago

🚨 New preprint 🚨 Massive shoutout to first author @abinagui.bsky.social !!! The common view is that regenerative competence declines with age. We challenge this idea by showing that axolotl tail regenerative competence is emerges during a defined embryonic window. www.biorxiv.org/content/10.6...

Honoured to have been awarded the 2026 British Society for Developmental Biology Lewis Wolpert Medal - means so much; as i was Lewis’s last PhD student,recognition for continuing his legacy of public engagement & impact of our research on Thalidomide & Primodos survivors. bsdb.org/2026/03/24/2...

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Study of 8M biomed & life science articles finds those led by women spent 7 to 15 days longer in review than those led by men. Over a career, women's papers could spend 350 to 750 additional days in review. Delays could slow promotion, esp to full professor. www.the-scientist.com/women-s-rese...

Peer Review Timelines Show Gender Gap, Large Study Reports

A study of millions of life science papers revealed that manuscripts with women in key authorship roles spent longer between submission and acceptance.

the-scientist.com

I think the latest cover helps to remind us that Development is not just a faceless brand of a journal eager to line shareholder pockets - it's a group of people who share a love for #devbio and, in my experience, really are trying to do their best for their community. #not-for-profit

Development@dev-journal.bsky.social · 7mo ago

Issue 24 is complete! Marking the end of #biologists100, the cover features members of our community, including some featured 'extraordinary biologists' #100biologists, as well as our Editors and in-house team. Thank you to all our authors and reviewers, past and present, for their contributions.

Cover of the journal Development featuring the faces of different people.

A toolkit for mapping cell identities in relation to neighbors reveals conserved patterning of neuromesodermal progenitor populations @PLOSBiology.org

A toolkit for mapping cell identities in relation to neighbors reveals conserved patterning of neuromesodermal progenitor populations

by Matthew French, Rosa P. Migueles, Alexandra Neaverson, Aishani Chakraborty, Tom Pettini, Benjamin Steventon, Erik Clark, J. Kim Dale, Guillaume Blin, Valerie Wilson, Sally Lowell Patterning of cell fates is central to embryonic development, tissue homeostasis, and disease. Quantitative analysis of patterning reveals the logic by which cell-cell interactions orchestrate changes in cell fate. However, it is challenging to quantify patterning when graded changes in identity occur over complex 4D trajectories, or where different cell states are intermingled. Furthermore, comparing patterns across multiple individual embryos, tissues, or organoids is difficult because these often vary in shape and size. This problem is further exacerbated when comparing patterning between species. Here we present a toolkit of computational approaches to tackle these problems. These strategies are based on measuring properties of each cell in relation to the properties of its neighbors to quantify patterning, and on using embryonic landmarks in order to compare these patterns between embryos. We perform detailed neighbor-analysis of the caudal lateral epiblast of E8.5 mouse embryos, revealing local patterning in emergence of early mesoderm cells that is sensitive to inhibition of Notch activity. We extend this toolkit to compare mouse and chick embryos, revealing conserved 3D patterning of the caudal-lateral epiblast that scales across an order of magnitude difference in size between these two species. We also examine 3D patterning of gene expression boundaries across the length of Drosophila embryos. We present a flexible approach to examine the reproducibility of patterning between individuals, to measure phenotypic changes in patterning after experimental manipulation, and to compare of patterning across different scales and tissue architectures.

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We are proud to recognize & thank ‪The University of Edinburgh for its support of bioRxiv & medRxiv. Their commitment helps sustain open access to preprints in biology & medicine, ensuring timely and globally-available sharing of scientific knowledge. Thank you! 💚 #bioRxiv #medRxiv #OpenScience

The words Thank you. We appreciate your support. openRxiv. on a white background with green gradient dots in the corners for the border.

"Because I had a long incubation time, I’m more resilient to the stress that comes with an academic career" Thank you Eve Seuntjens @eveseuntjens.bsky.social for sharing your career journey and your advice to people currently in the endless postdoc period #AcademicLife Read our interview with Eve:

Because I had a long incubation time, I'm more resilient to the stress that comes with an academic career - the Node

No such thing as a standard career path – an interview with Eve Seuntjens

thenode.biologists.com

Incredibly transformative for young people. So far I benefited from BSDB travel grants to go to conferences, attended a CoB workshops in 2019 & got a Development travel fellowship in 2023 to visit another lab to explore new ideas! Couldn’t have done this without the @biologists.bsky.social support!

Sally Lowell@cellysally.bsky.social · last yr.

Now @steveroyle.bsky.social tells us the many ways that not-for-profit publisher @biologists.bsky.social supports and funds the activities of biologists. Stark contrast to some other publishers, who suck £££$$$ out of science and into the pockets of shareholders #biologists100

Steve Royle presenting a slide inviting people to apply to organise a CoB funded workshop

Are you enjoying all the exciting science at #biologists100? Want to spread the love of developmental biology to your friends and family? Together with @bsdb.bsky.social, we've produced a documentary video to showcase the fascinating world of #DevBio: 🎥

BSDB - The Fascinating World of Developmental Biology (full length)

In this half-hour long documentary we showcase some of the beauty, as well as the translatability, of developmental biology research being undertaken current...

youtu.be