Evolution of transposons as controlling elements https://www.biorxiv.org/content/10.64898/2026.08.24.746577v1
Valeriy Kutsyna
@valeriyk1.bsky.social
Your nasty timer guy at #theconferencetoendallconferences Average slug enjoyed at @svobodalab.bsky.social
New paper @natcellbio.nature.com! We propose to understand embryo implantation as active wetting. Embryos from older mothers spread less because they are too contractile and viscous. Experiments by @katecavanaugh.bsky.social and theory by MJ Franco-Oñate in my group. www.nature.com/articles/s41...
Elevated contractility drives implantation failure in mouse embryos from aged females - Nature Cell Biology
Cavanaugh et al. show that embryos from aged mice have increased contractility and tissue viscosity on embryonic day 4.5, which leads to poor spreading and attachment. Similar age-associated mechanica...
nature.com
Kate Cavanaugh@katecavanaugh.bsky.social · 2w ago🧵 What if one reason fertility declines with age isn’t just genetic-but mechanical? Thrilled to share our new paper in @NatureCellBio : Elevated contractility drives implantation failure in mouse embryos from aged females… here’s what we found 👇 www.nature.com/articles/s41... 1/11
It's not too late to share the clicks from the last “RNA-guided genome protection” @embo.org in Switzerland 🇨🇭 what a great time! A dream come true meeting the RNAi guys that I’ve cited in my works since 2016 🥹 #RNAsky #genomeevolution
EMBO Workshop “RNA-Guided Genome Protection,” Caux 🇨🇭 My first time in Switzerland, and for such a great reason! Amazing place, great ideas, old friends and new faces all at once. @valeriyk1.bsky.social and I here with a slug story we’re thrilled to share 🐌 🧵
JASPAR 2026 is out 🎉 The new release massively expands the TF motif collections and adds a dedicated DeepLearning collection of motifs learned from deep learning models. Database: jaspar.elixir.no Paper (NAR): doi.org/10.1093/nar/... 🧵1/2
JASPAR: An open-access database of transcription factor binding profiles
JASPAR is the largest open-access database of curated and non-redundant transcription factor (TF) binding profiles from six different taxonomic groups.
jaspar.elixir.no
Excited to share our new @narjournal.bsky.social paper! Using ReLo and AlphaFold, we described a network of interactions between Drosophila piRNA pathway factors suggesting new links how they coordinate to ensure transposon silencing and genome integrity. academic.oup.com/nar/article/...
Our collaboration with @mbonhivers.bsky.social is now out in @plosbiology.org! 🎉Using U-ExM, we mapped the formation of the flagellar pocket collar in T. brucei. Huge thanks to everyone involved — one step closer to #PhDone! #ExM #oneringtorulethemall #Bilbo1 #trypanosoma #protistsonsky
PLOS Biology@plosbiology.org · 11mo agoThe flagellar pocket collar (FPC) is a cytoskeletal structure essential for nutrient uptake & immune evasion in #Trypanosome. @mbonhivers.bsky.social &co use U-ExM to provide novel insights into FPC biogenesis, and reveal 2 unknown cytoskeletal structures @plosbiology.org 🧪 plos.io/4n3bWi6
“Scientists’ salaries in the Czech Republic are significantly lower than in Western Europe, which makes it difficult to attract top international talent,” says Meritxell Alberich Jordà, one of the Forbes Top Women Scientists in the Czech Republic forbes.cz/nejvetsi-brz...
Největší brzda vědy? Kurýr si v Česku vydělá víc než univerzitní profesor
Kvůli nízkým platům ve vědě přichází Česko o řadu talentovaných lidí, kteří odcházejí dělat špičkovou vědu do světa.
forbes.cz
It is with great sadness that we share the news of the death of our founder, colleague, mentor and friend, Professor Sir John Gurdon. His vision and dedication will continue to inspire generations of scientists. 🔗 www.gurdon.cam.ac.uk/nobel-laurea...
Previously on BioRxiv, and now a final version of our paper is out! What a great lesson in plant self-organization: Auxin targets its own transporter through a cell-surface kinase complex in a positive feedback loop www.cell.com/cell/fulltex...
ABP1/ABL3-TMK1 cell-surface auxin signaling targets PIN2-mediated auxin fluxes for root gravitropism
In gravistimulated roots, gravity perception in the columella redirects the flow of the plant hormone auxin toward the lower root side, where it inhibits cell elongation for downward root bending. Thi...
cell.com
✨ For the first time ever, the IMG PhD Conference stepped outside institute grounds! ✨ 🏆Best Presentation Awards: Flash-talk: Magdalena Havlová Short talk: Irina Ribeiro Bas Talk: Veronika Niederlová Poster: Kriti Attri
Wow, that was amazing! We thank everyone for attending the V4SDB 2025 meeting! You all made it an excellent conference, where we had the opportunity to hear from outstanding speakers,share ideas and experiences, and of course have some unforgettable time during social activities!
What a great looking organoids though
PLOS Biology@plosbiology.org · last yr.In vitro model of porcine placental development: @crm110.bsky.social &co develop a swine trophoblast #organoid model that mimics in vivo #trophoblast diversity & gene expression, providing a platform for studying #placental biology & #MaternalFetalInteractions @plosbiology.org 🧪 plos.io/47jf3yd
Argonautes are coming :-) ... soon at @imgprague.bsky.social ... finishing preparations. Still missing a few things like drums, guitar, badges, beer ... but it's under control. I think. I hope. :-)) #argonautes2025
To recognise and celebrate @svobodalab.bsky.social's pivotal contribution to Woodstock Bio2 + Night Science, #TCTeAC, I am starting this "What Petr Svoboda did at Woodstock?" thread. If you were there - #contribute and #retweet. "Petr Didn’t Submit an Abstract. #TCTeAC Submitted to Him."
🥂This was the highlight of my year. The "instigators", led by local master of the ceremony @svobodalab.bsky.social will never forget the privilege of organizing it and i think every participant will treasure the experience forever ❤️ @nature.com @josiegz.bsky.social www.nature.com/articles/d41...
Scientific bedlam at the world’s weirdest and wildest research conference
Woodstock Bio2 + Night Science aimed to encourage collaborations through creativity. The walk-on music for presentations was fun, too.
nature.com
Talks were selected & the final program was built. It will appear on the website the next week. There are three weeks left till the registration deadline! This is probably the main RNA silencing meeting in 2025 - looking at silencing from the perspective of effector proteins. argonautes.img.cas.cz
The Argonautes – 2025
argonautes.img.cas.cz
Petr Svoboda@svobodalab.bsky.social · last yr.ARGONAUTES 2025 The grassroot meeting of Argonaute afficionados is looking for afficionados! Full coverage of Argonautes from prokaryotes to #RNAi, #piRNA and #microRNA Join us in Prague at @imgprague.bsky.social during 27-30/8, 2025. Registration, program and more info here: argonautes.img.cas.cz
Another day, another wonder; Archea parasite with a circular genome of only 238Kbp (!) found within a dinoflagellate. It only encodes for replicative machinery: can replicate but not sustain itself, making that line between life and non-life blurry! What a life www.biorxiv.org/content/10.1...
I can’t think of many countries, where a kind doctor would spend an hour injecting vaccine boosters on half the diseases in existence. After coming with a tick bite complaint… at 10pm! Czech healthcare rules!
Thank you for today’s seminar at @imgprague.bsky.social !
Adam Obr@obradam.bsky.social · last yr.Here are my 5 (not so standard) rules for communicating science to general public: 1) People are not stupid. They just don't have the knowledge. Yes, people can be clever and yet still be uninformed about cell biology. People also can know everything about cell biology and be completely dumb.
Opus magnum of my former #PhD student @akanksha-jain.bsky.social. She brought the power of #lightsheet imaging to the #Treutlein lab. #Organoids #singlecells #bigdata #imageanalysis You have learned much #Akanksha. You are a #JEDI now. ❤️👏 www.nature.com/articles/s41...
Morphodynamics of human early brain organoid development - Nature
Human brain morphodynamics are explored using organoids.
nature.com
Don’t miss this fantastic workshop at @imgprague.bsky.social !
Itai Yanai@itaiyanai.bsky.social · last yr.In Prague on Monday? Join my night science workshop on the creative process in science: openness, improvising ideas, how a hypothesis can be a liability, AI for hypothesis generation, import/export of ideas, puzzle switching, the 2 languages, questions, contradictions & awe 🙏 @svobodalab.bsky.social
I am heartbroken about the loss of many labs at the Weizmann Institute yesterday in the missile attack. Dear scientists there: please know that you are not alone. Like many many others, I support you and am standing by to help you in any way I can.
A 2-second video capturing Sven’s existential crisis: @stripplab.bsky.social torn between striking a pose as a death metal vocalist or as a serious scientist… #TCTeAC
What do you write at the end of the #TCTeAC survey email?
