Is generalized epilepsy a seizure of the whole brain or a specific brain network? In our new paper out now in @naturecomms.bsky.social, we investigate this by combining brain abnormalities and DBS with the human connectome. Paper: nature.com/articles/s41... A 🧵 below:

A generalized epilepsy network derived from brain abnormalities and deep brain stimulation - Nature Communications

Ji et al. identify an idiopathic generalised epilepsy network that links heterogeneously distributed brain abnormalities to a common brain network and deep brain stimulation sites which reduce general...

nature.com

About 12,000 people globally have signed up and the United States and Canada are lagging behind. It is mostly video content and enjoyable. The course closes for feedback analysis and development at the end of March so I challenge you to jump on board. mooc.utas.edu.au/course/20278...

Neurologists use videos to augment the clinical examination, and new AI methods promise to transform these videos into granular biomarkers. Here, we review the fascinating past, present and future of AI-powered video analyses in clinical neurology. Enjoy! jamanetwork.com/journals/jam...

Computer Vision in Clinical Neurology and AI Augmentation of the Neurological Examination

This narrative review outlines recent advances and challenges in technologies arising from computer vision, a branch of artificial intelligence (AI), which has the potential to improve clinical neurol...

jamanetwork.com

Pretty sure I don‘t have to introduce Andy, so to make it very short: interested in DBS and brain networks? Check out this super exciting new institute in Cologne!

Andreas Horn@andreas-horn.de · 2y ago

I am excited to announce that I will be founding an institute for network stimulation at the University Hospital Cologne – already this coming May!

What brain regions are involved in causing psychotic symptoms? Take a moment away from the existential dread about the future of science, and join me in this summary of some incredibly cool stuff that could help patients! 1/n🧵

Do lesions that cause psychosis fall into a common brain network? Exciting new work by @andrewpines.bsky.social, @shansiddiqi.bsky.social and colleagues – tweetorial below by the first author, paper here: jamanetwork.com/journals/jam...

Mapping Lesions That Cause Psychosis

This case-control study analyzes published cases of lesion-induced psychosisTo assess whether lesions that cause secondary psychosis have functional connections to a common brain circuit

jamanetwork.com

Andrew Pines@andrewpines.bsky.social · 2y ago

What brain regions are involved in causing psychotic symptoms? Take a moment away from the existential dread about the future of science, and join me in this summary of some incredibly cool stuff that could help patients! 1/n🧵

New Center paper out at JAMA psychiatry: jamanetwork.com/journals/jam...

Mapping Lesions That Cause Psychosis

This case-control study analyzes published cases of lesion-induced psychosisTo assess whether lesions that cause secondary psychosis have functional connections to a common brain circuit

jamanetwork.com

Andrew Pines@andrewpines.bsky.social · 2y ago

What brain regions are involved in causing psychotic symptoms? Take a moment away from the existential dread about the future of science, and join me in this summary of some incredibly cool stuff that could help patients! 1/n🧵

Awesome thread by @andreashorn.org on his recent paper on STN DBS for dystonia. Details a great collaboration and his thought process as the study evolved. @braincircuits.bsky.social

Andreas Horn@andreas-horn.de · 2y ago

🚨Interested in Dystonia?🚨 @braincircuits.bsky.social GPi DBS for dystonia is effective. More recently, STN DBS has been investigated, as an alternative. In what enfolded like a stunning thriller to me, Konstantin Butenko tells a tale of two networks… www.pnas.org/doi/10.1073/...

Cool to see our work from @braincircuits.bsky.social featured in @sciam.bsky.social today. Great read on an interesting and bizarre neurological condition. www.scientificamerican.com/article/how-...

How Rare ‘Alice in Wonderland Syndrome’ Warps Reality

Researchers are learning what causes Alice in Wonderland syndrome, a rare neurological condition that can appear to warp bodies, time and reality itself

scientificamerican.com

Wonderful christmas read featuring our network mapping work on Alice in Wonderland syndrome- a bizarre and fascinating perceptual disorder. Kudos @sciam.bsky.social @foxmdphd.bsky.social @braincircuits.bsky.social www.scientificamerican.com/article/how-...

How Rare ‘Alice in Wonderland Syndrome’ Warps Reality

Researchers are learning what causes Alice in Wonderland syndrome, a rare neurological condition that can appear to warp bodies, time and reality itself

scientificamerican.com

Spanning spatial scales with functional imaging in the human brain; initial experiences at 10.5 Tesla https://www.biorxiv.org/content/10.1101/2024.12.20.629800v1

I think a fun teaching exercise for medical students would be to each take a common clinical pearl and trace the citations until you find the primary data it's based on.

Showed a glimpse of a new atlas that we're building in Paris yesterday. Pretty excited about it and implications for network modeling.

Can computer vision help us turn clinical videos into quantifiable digital biomarkers of Dystonia? Our recent paper suggests yes! Let‘s recap first. www.nature.com/articles/s41...

Head movement dynamics in dystonia: a multi-centre retrospective study using visual perceptive deep learning - npj Digital Medicine

npj Digital Medicine - Head movement dynamics in dystonia: a multi-centre retrospective study using visual perceptive deep learning

nature.com

Hypothalamic deep brain stimulation augments walking after spinal cord injury (SCI). #NatureMedicine #medsky #scisky "Targeting specific brain regions to maximize the engagement of spinal cord-projecting neurons in the recovery of neurological functions after SCI." www.nature.com/articles/s41...

Hypothalamic deep brain stimulation augments walking after spinal cord injury - Nature Medicine

Whole-brain anatomical and activity surveys identify the lateral hypothalamus as a key driver of recovery from spinal cord injury, leading to a deep brain stimulation therapy that augments the recover...

nature.com

Combining electrophysiological, anatomical and functional brain maps reveals networks of beta neural activity that align with dopamine uptake. https://buff.ly/4eQnzET

Brain Activity: Unifying networks of a rhythm

Combining electrophysiological, anatomical and functional brain maps reveals networks of beta neural activity that align with dopamine uptake.

buff.ly

Our new paper in @science.org shows that misinformation evokes more outrage than trustworthy news, and when it does it’s shared more & read less. bsky.app/profile/will...

William J. Brady@williambrady.bsky.social · 2y ago

New paper out in @ScienceMagazine! In 8 studies (multiple platforms, methods, time periods) we find: misinformation evokes more outrage than trustworthy news, when it does it's shared more + ppl are less likely to read before sharing. w/ @killianmcl1 @Klonick @mollycrockett 🧵👇

Have you ever felt like you're in a surreal world where sizes and scales are all warped? No, it's not a fantasy—it's a real medical condition! Come dive with me into this mind-bending phenomenon called Alice in Wonderland Syndrome (AIWS): onlinelibrary.wiley.com/doi/abs/10.1...

Tremor is common, and measuring its dynamic characteristics is important for disgnosis and prognostication. Marker-based motion capture helps, but is very resource-intensive. What if we could analyze tremor just with a smartphone video?! 🧠 www.nature.com/articles/s41...

Validation and application of computer vision algorithms for video-based tremor analysis - npj Digital Medicine

npj Digital Medicine - Validation and application of computer vision algorithms for video-based tremor analysis

nature.com

Tremor is common, and measuring its dynamic characteristics is important for disgnosis and prognostication. Marker-based motion capture helps, but is very resource-intensive. What if we could analyze tremor just with a smartphone video?! 🧠 www.nature.com/articles/s41...

Validation and application of computer vision algorithms for video-based tremor analysis - npj Digital Medicine

npj Digital Medicine - Validation and application of computer vision algorithms for video-based tremor analysis

nature.com

Very much looking forward to this talk tomorrow by our very own @fredschaper.bsky.social together with Stanford's Robert Fisher on Epilepsy and How to get jobs in Academia! Join us on stimulatingbrains.org! @stimulatingbrains.org

We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how: docs.bsky.app/docs/advance... #AcademicSky #HigherEd #Altmetrics

Action Intent Links | Bluesky

Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...

docs.bsky.app

www.neurology.org/doi/10.1212/... Mark Hallett’s Wartenberg lecture, dedicated to his mentor the late David Marsden

Functional Neurologic Disorder, La Lésion Dynamique | Neurology

Functional neurologic disorder is common and a significant cause of disability and stress in neurologic patients. The nature of this disorder has been unclear. Originally called hysteria, the disorder...

neurology.org

One of most overlooked issues of past literature is the 'miracle' of #brain surgery in #functional patients. Cooper was a pioneer in the field but some of his success came from this, as we discussed recently in www.neurology.org/doi/10.1212/...

PSA BlueSky allows you to curate your feed. In addition to “following”, you can choose (in your settings) to only see the feed you prefer. I deleted “discover” and replaced it with “popular with friends”. Less noise, more signal.

a black and white photo of a man in a suit covering his face with his hands .

ALT: a black and white photo of a man in a suit covering his face with his hands .

media.tenor.com

Have you ever felt like you're in a surreal world where sizes and scales are all warped? No, it's not a fantasy—it's a real medical condition! Come dive with me into this mind-bending phenomenon called Alice in Wonderland Syndrome (AIWS): onlinelibrary.wiley.com/doi/abs/10.1...

New Viewpoint on Functional Movement Disorder in prodromal Parkinson's: "Loss of dopaminergic neurons may increase likelihood of a mismatch between predictions of the sensory consequences of planned movement and actual sensory feedback." movementdisorders.onlinelibrary.wiley.com/doi/full/10....

Can we induce euphoria and mania with DBS in Parkinson? You bet we can as was shown by Coutinhou and colleagues in Tremor journal. Watch out for folks with baseline ICD, DDS or bipolar disorder. That deep ventral contact on DBS lead may trigger this…