@curealzheimersfund.bsky.social People who have Alzheimer's disease pathology but no loss of cognition. Why? Discoveries we are making give new insights! See presentations by Isabel Castanho @isabelscst.bsky.social Pourya Naderi @pouryany.bsky.social and Giulia Pegoraro at #AAIC26 here in London.

People get Alzheimer’s disease pathology really badly in their brains and yet they don’t have cognitive loss. How? Attend these #AAIC26 presentations to see discoveries being made to answer that question. @isabelscst.bsky.social @pouryany.bsky.social

The plan to kill research in USA www.nytimes.com/2026/06/20/o...

Opinion | The Science That Turned Lizard Venom Into GLP-1s Is Under Attack

nytimes.com

Join us! we are looking for a Bioinformatics Data lead. tinyurl.com/winhidelab. We are looking to the future with our @curealzheimersfund.bsky.social funded program to discover the way Alzheimer's functions using Genedexing: making sense out of Alzheimer’s gene signatures tinyurl.com/ADresilience...

Integrating Single-Cell Genomics for Pathways to Protection and Resilience Against Alzheimer’s Disease – Cure Alzheimer's Fund

Amyloid beta pathology starts to build up in the brain years before tau tangles appear in Alzheimer’s disease (AD) patients. However, the onset of

tinyurl.com

Bioinformatics and Data infrastructure lead wanted! We are rapidly growing, and want you to grow with us. Tightly interacting team with cool tools and projects. Seeks data centric builder and visioneer. Apply tinyurl.com/2exv3mrj. (lab site tinyurl.com/yc7rczck) Please share to your community.

@molneurodegen.bsky.social shorturl.at/B5qbB Out now.

I am honored to celebrate our publication. I work together with these future leaders in Alzheimer's research. Will AD become a controllable disease? If we can find our natural defensives and make them stronger?

Isabel Castanho, PhD@isabelscst.bsky.social · 10mo ago

Thrilled to share that our paper “Molecular hallmarks of excitatory and inhibitory neuronal resilience to Alzheimer’s disease” is now out in Molecular Neurodegeneration! 👉 link.springer.com/article/10.1... #Alzheimer #Resilience #Neuroscience

Time to better understand the actual challenges. We will open new ideas! Join us. #FOGBoston June 25 13:50 hrs Festival of Genomics. Comments? Ideas? Message me

Thrilled. Why? Because Peter was supported by SANBi to start this journey 25 or so years ago?

Peter van Heusden (he/him) 🗿@pvanheus.bsky.social · last yr.

My first funded grant has been one researching novel meningitis diagnostics with partners from INRB in the DRC. The research site is in Goma, now in territory controlled by M23, and I'm proud to report that my colleagues in Goma are still running a meningitis sample referral and diagnostics network!

#rnasociety.bsky.social Real honour to get to present to the African RNA Salon - upcoming RNA biologists across Africa interested in translational RNA medicine. Qs: How can RNA technology impact public health in resource poor communities? Qs: is something as simple as refrigeration a show stopper?

Latest @garymarcus.bsky.social is a great explainer about why LLMs (will always) hallucinate. garymarcus.substack.com/p/why-do-lar...

Why DO large language models hallucinate?

The Henrietta Chronicles continue, guest starring Harry Shearer

garymarcus.substack.com

Brain tissue artificially expanded to show how neurons wire together @nature.com www.nature.com/articles/s41... www.nature.com/articles/d41...

Light-microscopy-based connectomic reconstruction of mammalian brain tissue - Nature

A technique called LICONN (light-microscopy-based connectomics) allows mapping of brain tissue at synapse level and simultaneous measurement of molecular information, thus enabling quantification of c...

nature.com

@iscb.bsky.social In depth African Bioinformatics at #ASCB2025 Cape Town. Honoured to see fruits of early days of Cap_dev bioinformatics in Africa! Best practice prevails. Come join us - we seek researchers as interns and for post doctoral training. research.bidmc.org/winston-hide

superb experience to be embedded in great science with our next generation of leaders @isabelscst.bsky.social

Isabel Castanho, PhD@isabelscst.bsky.social · last yr.

#ADPD2025 was exhausting 😴 but so thrilling 🤩 The discussions really energized me! ⚡🔋 I got to chat w/ collaborators, mentors & promising students. 💬 And the city of Vienna is beautiful!! 🏛️👑🎻🖼️ I returned to Boston feeling inspired, creative & motivated. 💪🏻🙌🏻 In the pic w/ PI @winhide.bsky.social

With just a few words - human chronic disease exposed through diet?

Science Blog@scienceblog.com · last yr.

African Diet Reverses Inflammation in Just Two Weeks While Western Foods Trigger Disease Markers Switching from a traditional African diet to Western food for just two weeks triggered inflammation, weakened immune responses, and activated disease-related processes in healthy men, according to…

#adpd2025 insights into the Alzheimer’s continuum. 4/4/25 @19:25 @pouryany.bsky.social will present our new approach to discovering validated targets for AD therapy

You know about the PAN-GO #Functionome, but have you explored the power of the Functional Category search? Learn how to find #humangenes of interest in just a few clicks, using the Functional Categories community.alliancegenome.org/t/8362 🧬🧪 #GOSlims ICYMI: community.alliancegenome.org/t/8343

Come join our adventure @sangerinstitute.bsky.social 👇🏾

Open Targets@opentargets.org · last yr.

We're recruiting! ➡️ (Senior) bioinformatician: join a collaborative project with @mhaniffa.bsky.social and Mo Lotfollahi, supporting the analysis of single-cell and spatial transcriptomics studies to train AI-based foundation models Apply by 25 March sanger.wd103.myworkdayjobs.com/en-US/Wellco...

The University of Oxford is seeking two Research Assistants with an interest in brain ageing research, dementia or cognitive disorders. Closing date: 10th April. www.dementiaresearcher.nihr.ac.uk/job/research...

Research Assistant: Cognitive Neurology

The University of Oxford is seeking two Research Assistants with an interest in brain ageing research, dementia or cognitive disorders.

dementiaresearcher.nihr.ac.uk

Interested in doing a sabbatical at EMBL, at one of its 6 sites in Barcelona, Cambridge, Grenoble, Hamburg, Heidelberg or Rome? Funding call with deadline 15 June, decisions in July. www.embl.org/about/info/s...

Due recognition. Cannot express my joy in seeing nature publish the pioneering role of Alan Christoffels and the South African National Bioinformatics institute in African capacity development. I started SANBI. Alan was one of our first graduates! doi: doi.org/10.1038/d441...

Alan Christoffels: Building bioinformatics in Africa

The leader of SANBI on efforts to address skills shortages and the lack of diversity

doi.org

"The reality became clear: Ice detention isn’t just a bureaucratic nightmare. It’s a business. These facilities are privately owned and run for profit."

chasingmicrobes@chasingmicrobes.bsky.social · last yr.

#IChoseUWC Social Media Competition Winners 🏆 Thank you for sharing your unique stories with us! #IAmUWC

Working at the forefront of human disease RNA medicine is amazing. Watching what is possible. ‘The art of the possible’ becomes ‘the art of resilience’. You can’t stop the tide. You can’t hide truth.

Waldo Jaquith@waldo.net · last yr.

mRNA vaccines are the biggest breakthrough in disease prevention and treatment in decades. We're curing *cancer* with mRNA vaccines. To eliminate research in this field, at this moment, is fall-of-the-empire-grade stuff.

i honestly have never seen a political leader so thoroughly destroy their credibility so quickly and, on the other side, it is abundantly clear that if anyone can claim a genuine leadership of large parts of the democratic party, it is AOC.

George Pearkes@peark.es · last yr.

Folks is it good when your own party's leadership in the House is dropping "listen to the women" and MLK quotes on you while swing state members of your caucus are talking about new leadership

An account of what killing PEPFAR will do to S Africa www.spotlightnsp.co.za/2025/03/13/i...

In-depth | How much does our HIV response depend on US funding?

After the US slashed global aid, the South African government stated that only 17% of its HIV spending relied on US funding. But some experts argue that US health initiatives had more bang for buck th...

spotlightnsp.co.za

New @science.org On the US-Canada deep collaborations and partnership in science that absolutely need to be preserved despite "contemptuous musings on annexation to a tariff war" science.org/doi/10.1126/...

Congrats to Natalia Benetti @nataliabenetti.bsky.social of the Mundlos lab, who has received a @ec.europa.eu Marie Skłodowska-Curie Actions Postdoctoral Fellowship! In her project SynLncRNAs, Natalia will use synthetic biology to uncover mechanisms of gene regulation by long non-coding RNAs in vivo.

Great to see true vision in person.

Ewan Birney@ewanbirney.bsky.social · last yr.

I will soon become the Executive Director of @embl.org, leading EMBL with Peer Bork whilst EMBL finds its next Director General, my colleague, Jo McEntyre will become @ebi.embl.org's Interim Director. Jo's leadership and experience means I am confident EMBL-EBI will flourish over this time

Hidelab has a new website! Come join us! research.bidmc.org/winston-hide

Hide Laboratory

systems biology of alzheimer's disease

research.bidmc.org

Winston Hide@winhide.bsky.social · 2y ago

What are the molecular and cellular hallmarks of resilience and resistance to Alzheimer's Disease? Awesome discoveries with @pouryany.bsky.social @isabelscst.bsky.social We’re growing our team—deliver translation with omics! #cureAlzheimersFund #Postdoc shorturl.at/bGyUqhife hidelab.net