We’ve been awarded European Commission Choose Europe for Science Co-fund at Uni of Birmingham! MOBILITY will fund 6 talented postdoctoral researchers at the transition to independence. All within remit of Molecular Biodiscovery. Applications open in October 😀👍. www.birmingham.ac.uk/news/2026/bi...

First UK institution awarded Choose Europe for Science grant - University of Birmingham

Birmingham awarded £1.2m in ERC funding to attract talent from outside of Europe

birmingham.ac.uk

We’ve been awarded European Commission Choose Europe for Science Co-fund at Uni of Birmingham! MOBILITY will fund 6 talented postdoctoral researchers at the transition to independence. All within remit of Molecular Biodiscovery. Applications open in October 😀👍. www.birmingham.ac.uk/news/2026/bi...

First UK institution awarded Choose Europe for Science grant - University of Birmingham

Birmingham awarded £1.2m in ERC funding to attract talent from outside of Europe

birmingham.ac.uk

Our lab at Pitt is looking to hire a technician. Ideal candidate would be a recent graduate with some cell biology skills, looking to expand their experience before applying to a PhD program in a couple of years. If you are this person, interested in DNA replication, please email me. moiseevalab.com

Why are telomeres endogenous sources of replication stress? Max Douglas and collaborators use reconstituted human replisomes with telomeric templates to dissect how core components of telomeres influence different aspects of the replication process link.springer.com/article/10.1...

Inhibition of lagging strand replication by G-rich telomeric DNA and the shelterin subunit POT1 - The EMBO Journal

Telomeres preserve stable eukaryotic chromosomes by protecting the natural chromosome ends from DNA repair but pose a persistent challenge to the replication machinery and an endogenous source of repl...

link.springer.com

📣 Applications are open for the next NAR Early Career Investigator (ECI) Advisory Board cohort! Work with Executive Editors, help shape journal strategy, and gain insight into peer review during a 2-year term. Apply by 1 Nov 2026: lnkd.in/g233ZCAf #ECR #NAR #AcademicPublishing #MolecularBiology

1/ Very excited to share the first publication from my lab! In this work, we developed an efficient strategy to precisely mutate mammalian histone genes in their native genomic context using CRISPR prime editing: www.nature.com/articles/s41...

Identifying critical lysines in mammalian histone H3 with high-throughput CRISPR prime editing - Nature Genetics

This study uses a precise and efficient clustered regularly interspaced short palindromic repeats (CRISPR) prime editing system to substitute lysine residues in histone H3, individually or in combinat...

nature.com

My department @eth-dbiol.bsky.social at ETH Zurich is hiring for a tenured professor in mol cell bio and biochemistry (associate/full). The position is within the Institute of Biochemistry (www.bc.biol.ethz.ch) and it is fairly open within their scope of research. www.nature.com/naturecareer...

Professor of Molecular Cell Biology and Biochemistry - Zurich, Switzerland job with ETH Zurich | 12861386

The Department of Biology at ETH Zurich invites applications for the above-mentioned tenured professorship at the Institute of Biochemistry

nature.com

Very excited to share our new Nature study! We discovered that replication stress stabilizes CTCF-dependent chromatin loops enclosing stressed nascent DNA, where G9a-mediated heterochromatin protects it from nucleolytic degradation. rdcu.be/frzLg Huge thanks to all our collaborators and co-authors!

Replication-stress-induced chromatin loops protect fork stability - Nature

Replication stress induces the formation of transient chromatin loops that enclose de novo heterochromatin-enriched stalled replication forks.

nature.com

AlphaFold is transforming how we study DNA replication, predicting protein structures and interactions to unlock new biological insights. A powerful example of AI+HPC accelerating discovery. blog.bham.ac.uk/bear/2026/06... @unibirmingham.bsky.social @agagambus.bsky.social #AlphaFold #Bioinformatics

🧬 ⛓️‍💥 Our paper is now out in @natsmb.nature.com ! We examined the fate of replication forks that collapse at single-strand DNA breaks (SSBs) in vertebrates 🐸, comparing the consequences of collapse at single vs convergent forks. www.nature.com/articles/s41...

Distinct repair outcomes from single and convergent replication fork collapse - Nature Structural & Molecular Biology

Here the authors show that collapse of single replication forks causes recombination, end fusions or degradation but does not restart DNA synthesis. In contrast, collapse of convergent forks completes...

nature.com

If you have experience in biochemistry/cryo-EM, are interested in DNA replication, and would like to do a postdoc in New York - our lab has positions available! Just DM or email me with your CV.

Come and start your group at @ki.se! ki.se/en/about-ki/...

Assistant Professor recruitment programme 2026

Karolinska Institutet continues to grow a global community of excellence. In summer 2026, KI is inviting applications for 21 Assistant Professor positions in medicine and health. We are once again loo...

ki.se

We are looking for a PhD student to study chromatin changes related to heart regeneration, in collaboration with @bakkerslab.bsky.social . Please share and apply! www.hubrecht.eu/nl/vacature/...

Excellent opportunity @mrc-lms.bsky.social for a human physiologist to start their own group. Deadline 4th May. Core funding, excellent package. Please repost! lms.mrc.ac.uk/work/vacanci...

Programme Leader Track - MRC Laboratory of Medical Sciences

lms.mrc.ac.uk

The University of Birmingham’s College of Medicine and Health is offering a 2-year Springboard Fellowship to help you start your own lab. Previous award holders have secured externally funded fellowships. Deadline: 8th June 2026 17:00 BST The Fellowship Academy www.birmingham.ac.uk/about/colleg...

Internal Funding Opportunities - University of Birmingham

The University of Birmingham and College of Medicine and Health provide several funding opportunities to research-active staff looking to further develop their research activity.

birmingham.ac.uk

Congratulations to Dr Tianyi Zhang and Dr Layara Abiko@layaraabiko.bsky.social, who are recipients of Career Development Awards from Wellcome Trust. www.birmingham.ac.uk/news/2026/su...

Success for Birmingham researchers in Wellcome Career Development Awards - University of Birmingham

Researchers at the University of Birmingham have been successful in the most recent round of the Wellcome Career Development Awards.

birmingham.ac.uk

It’s official: the UK is rejoining Erasmus! 👏🇪🇺

We're delighted to announce Professor Daniel Tennant as the recipient of the 2027 Sir Philip Randle Lecture! Work in the Tennant Research Group - Birmingham UK has been instrumental in identifying new pathways through which cells modify their metabolism under hypoxia.

Proud to share the yeast telomerase structure, led by the talented @hongmiaohu.bsky.social in collaboration with the Wellinger and Chartrand labs. Discovered 37 years ago and took us nearly 7 years but totally worth the wait 😍. www.science.org/doi/10.1126/... www.youtube.com/watch?v=gFE4...

Cryo-EM structure of yeast telomerase

YouTube video by MRC Laboratory of Molecular Biology

youtube.com

MRC Laboratory of Molecular Biology@mrclmb.ac.uk · 4mo ago

Led by Investigator Scientist @hongmiaohu.bsky.social, @kellythd-nguyen.bsky.social’s group in the LMB’s Structural Studies Division have produced the first ever structure of telomerase from yeast. Read more here: mrclmb.ac.uk/news-events/... #LMBResearch #cryoEM 🧪

“I think it’s a real mistake to forget where the pipeline for all this begins.” John Diffley reflects on the importance of basic research, his mission to decode DNA replication and recreate it in the lab, and the scientific optimism of the 1960s that helped shape it. www.crick.ac.uk/news/2026-03...

PhD available with @overtonlab.bsky.social Sara Jabbari and me associated with our BBSRC sLoLa project! www.findaphd.com/phds/project... (UK students only)

Improving the solvent tolerance of E. coli by understanding the rules of accumulation at University of Birmingham on FindAPhD.com

PhD Project - Improving the solvent tolerance of E. coli by understanding the rules of accumulation at University of Birmingham, listed on FindAPhD.com

findaphd.com

We are excited to be recruiting into 3 Associate Professorship's in @oxfordbiochemistry.bsky.social. Come join us as a colleague and benefit from our vibrant and multidisciplinary environment. Reach out to me if you have any questions. Please repost! (tinyurl.com/48deybuu) (tinyurl.com/4pdvjaft).

🚨 Our new paper is out! 🙌 Bioorthogonal reactions often create bulky, non-native linkages-great for labeling, but not ideal for installing natural PTMs. We combine GCE with a chemoselective amide-bond forming reaction to install site-specific acylation PTMs. www.cell.com/chem/fulltex... 1/4

A modular genetic code expansion approach to site-specific lysine acylations

A modular strategy combining genetic code expansion with a selective amide bond-forming reaction enables the site-specific installation of lysine acylations on folded proteins. Acylboronates react sel...

cell.com

PhD position in our lab - 4-year funded by BBSRC and @nrpdtp.bsky.social in collaboration with @earlhaminst.bsky.social and Inspiralis Ltd. Open to UK fee qualifying students - UK citizens and citizens of Ireland (residency requirement), etc biodtp.norwichresearchpark.ac.uk/projects/how...

How do RNA molecules shape genome regulation in the nervous system? (AKAY_U26CASE) | Doctoral Training Partnership

This is open to Home Fee Status candidates only. This PhD project will investigate how RNA modifications influence the activity of topoisomerase I (TOP1), a crucial enzyme that regulates DNA…

biodtp.norwichresearchpark.ac.uk

Happy to see our work on defining a dependency map of short linear motifs out. We use base editing screens to install more than 80000 mutations into SLiMs in more than 4000 proteins to determine their contribution to cell fitness. www.nature.com/articles/s41...

A proteome-wide dependency map of protein interaction motifs - Nature Structural & Molecular Biology

Ambjørn and Meeusen et al. functionally characterize all reported and a comprehensive set of predicted short linear motifs (SLiMs) using base-editing screens, identifying 450 reported and 264 predicte...

nature.com

We are excited to be recruiting a new tenure track group leader in the Structural Studies Division at MRC LMB! It is an amazing place to start your own lab. @mrclmb.bsky.social Please get in touch if you have any questions. www.nature.com/naturecareer...

Research Group Leader Tenure Track - Structural Studies - LMB 2775 - Cambridge, Cambridgeshire (GB) job with MRC Laboratory of Molecular Biology (LMB) | 12854636

Research Group Leader Tenure Track Starting Salary £67,979 to £76,868 per annum MRC Laboratory of Molecular Biology, Cambridge, UK The MRC Laborato...

nature.com

Sjors Scheres@sjorsscheres.bsky.social · 6mo ago

Please spread the word: the Structural Studies Division @mrclmb.bsky.social is looking for a new tenure-track, independent group leader with an exciting plan in any area of Structural (Molecular & Cell) biology, in discovery biology and/or methods development. 🥳 mrc.tal.net/vx/mobile-0/...

DNA replication globally disrupts the epigenome. But does this create a chromatin-access opportunity for TF binding to facilitate cell identity change? Now 𝐫𝐞𝐩𝐥𝐢-𝐀𝐓𝐀𝐂-𝐬𝐞𝐪 shows 𝘥𝘦 𝘯𝘰𝘷𝘰 chromatin opening & TF binding occurs specifically post-replication, in cellular differentiation & reprogramming!

Post-replicative chromatin accessibility predicts cell fate change

Knudsen and colleagues use repli-ATAC-seq to compare replicated and unreplicated chromatin in two models of cell identity change. They find that lineage-specific elements are accessible earlier in rep...

cell.com

Best conference location ever! Thank you @fusionconf.bsky.social for the excellent DNA replication and repair conference 👍👍👍

I have multiple positions available to join my lab from this summer: #postdoc, #student and #technician. Adverts to follow but see www.saurinlab.com for further details. #senescence, #mitosis, #cellcycle, #phosphorylation are the key areas. Email me if interested.

To kickstart this new Bluesky account: We're hiring! The Bertolin Lab @dundee.ac.uk is looking for a postdoc to work on DNA-end homeostasis & genome stability, funded by Wellcome Trust Award. Exciting science, fantastic environment, founding role in the lab. Details in the flyer — get in touch! 👇