Class action lawsuit?

Reese Richardson@reeserichardson.bsky.social · 2mo ago

The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below)

Multiple postdoc/RA vacancies to work on the Wellcome-funded team project shown below. I also have vacancies to study senescence and to develop a chemical-genetic approach to inhibit specific cyclin/CDK complexes. See thread for details. DM or email me with any questions.

Excited to share our structural insights into how microtubules differentially guide phosphorylation of kinetochore-microtubule regulators, Ndc80 and MCAK, for chromosome segregation. Heroic efforts by Yiming Niu with a fun collaboration with Jennifer DeLuca lab! www.science.org/doi/10.1126/...

Microtubules guide Aurora B substrate geometries for accurate chromosome segregation

Cryo-EM reveals how kinetochore-microtubule attachment is regulated by Aurora B substrate accessibility on microtubules.

science.org

The Rockefeller University @rockefeller.edu · 4mo ago

Microtubules have been viewed as passive structural supports, but a study from @hirofunabiki.bsky.social in @science.org Advances redefines microtubules as active regulators, helping to prevent abnormalities in the number of chromosomes, a hallmark of cancer. 🔗: https://bit.ly/4v8miCC

We finally managed to write Ikers master thesis project together. Interesting and careful work on FAM122A. www.biorxiv.org/content/10.6...

www.sciencedirect.com/science/arti...

I have multiple positions available to join my lab from this summer: #postdoc, #student and #technician. Adverts to follow but see www.saurinlab.com for further details. #senescence, #mitosis, #cellcycle, #phosphorylation are the key areas. Email me if interested.

To kickstart this new Bluesky account: We're hiring! The Bertolin Lab @dundee.ac.uk is looking for a postdoc to work on DNA-end homeostasis & genome stability, funded by Wellcome Trust Award. Exciting science, fantastic environment, founding role in the lab. Details in the flyer — get in touch! 👇

Last days to apply this position in our group! Do join us in this great Institute @crg.eu, with great colleagues, and help shaping the science and culture of our lab!

Monica Bettencourt-Dias@monicabettencourt.bsky.social · 6mo ago

📣 Please spread: we’re hiring a Lab Manager! It is a critical position in our new lab. As our lab moves to Barcelona and joins the @crg.eu, we’re looking for a Lab Manager to help build the lab and set the lab atmosphere. 🔗 Apply here 👉 recruitment.crg.eu/content/jobs...

I watched much of Ian Chapman's (Head of @ukri.org) appearance this morning at @ukparliament.parliament.uk Science, Innovation and Technology Committee.. A few points and new information that bioscientists may find interesting... A 🧵

Two new papers from the lab published in The EMBO Journal! link.springer.com/article/10.1... By Kai Walstein, @louisa-hill.bsky.social and others – On role of M18BP1 in CENP-A loading link.springer.com/article/10.1... By Arianna Esposito Verza and others – On mechanism of activation of PLK1

@ukri.org Could you please make a statement about whether this will impact on grants already in review from autumn 2025? It's hard to accept grant opportunities closing, but even harder to accept the rug being pulled after review. Rumours of a 1-5% acceptance rate would be incredibly hard to take

UK Research and Innovation@ukri.org · 6mo ago

Today, we're sharing an open letter from our Chief Executive, Professor Sir Ian Chapman, outlining changes to UKRI investment approach, and addressing concerns about research funding and the financial position of STFC. Read his letter here: www.ukri.org/news/open-le...

At a time when the UK should be capitalising on its global reputation as a great place to do science, this is an enormous own goal. I am so sorry for all those who jobs are going to be impacted.

Mark A. Hanson@hansonmark.bsky.social · 6mo ago

Both MRC and BBSRC responsive modes now withdrawn until further notice. Existing applications unlikely to succeed (late 2025 round expecting 1-5% success rate). Listen, I get that UKRI wants to pivot. But killing both at once is devastating. Let's hope at least one opens by summer... #AcademicSky

PhD position in my lab!

Wholeheartedly agree with this. Well said www.theguardian.com/commentisfre...

Brooklyn Beckham and Prince Harry are the canaries in the coalmine. The children of Instagram will be next | Rhiannon Lucy Cosslett

A generation of overexposed children are being used by their parents for social media clout. What happens when they start to speak out, asks Guardian columnist Rhiannon Lucy Cosslett

theguardian.com

Please share! We've an exciting one-year postdoctoral position available in my group - drug discovery using HDX-MS for a Parkinson's disease target. Join us on high-impact, translational research at the cutting edge of structural biology. We're a friendly bunch! www.dundee.ac.uk/work-for-us/...

Postdoctoral Research Assistant - UOD2127

Closing date: Wednesday 18 February 2026, 23:59

dundee.ac.uk

We are also recruiting a Postdoc in cell/molecular biology! 3yr, fully funded by @cancerresearchuk.org more details here: news.cancerresearchuk.org/2025/11/27/s... Apply here: www.imperial.ac.uk/jobs/search-...

Spin doctors: taking on the challenge of tissue-specific cell cycle control - Cancer Research UK - Cancer News

A false start, a Nobel Prize and renewed hope – understanding cell cycle disruption over different tissues is complex. But we are getting there…

news.cancerresearchuk.org

Alexis Barr@alexisbarr.bsky.social · 7mo ago

We are recruiting a Postdoc in computational biology, together with @mariasecrier.bsky.social 4yr, fully funded by @cancerresearchuk.org, ideal for Postdocs wanting to develop their independence Applications open now: www.imperial.ac.uk/jobs/search-...

Group-based Prediction System (GPS) 6.0 gps.biocuckoo.cn Online server for protein Post-Translational Modifications Kinase-specific phosphosite prediction across 185 species! >10 other PTMs #NucAcidRes 2023 academic.oup.com/nar/article/...

We are back on Jan 19 at 3pm CET! Our first seminar for 2026 will feature Prof. Benjamin Turk (@benturklab.bsky.social) and Dr. Giorgia Massacci. Register to attend: tinyurl.com/PMCseminar2 Previous seminars: www.youtube.com/@PMCModularity

The best thing I’ve listened to all year. A brilliantly articulated vision about the dangers of AI which stresses the importance of societal pressure in demanding a safe future. Please consider listening and deciding for yourself if and how you can help open.spotify.com/episode/1S8F...

AI Expert: We Have 2 Years Before Everything Changes! We Need To Start Protesting! - Tristan Harris

Podcast Episode · The Diary Of A CEO with Steven Bartlett · 27/11/2025 · 2h 23m

podcasts.apple.com

2 recent preprints show the mitotic stopwatch monitors more than just mitotic delays - it protects against WGD, cell enlargement and other stresses that mildly activate p53. It may act to amplify p53 signals to suppress tumourigenesis www.biorxiv.org/content/10.1... www.biorxiv.org/content/10.6...

The mitotic stopwatch limits the proliferation of whole genome doubled cells

Whole genome doubling (WGD) is a frequent event in tumourigenesis that promotes chromosomal instability and tumour evolution. WGD is sensed indirectly due to the presence of extra centrosomes, which a...

biorxiv.org

We’re recruiting a Postdoctoral Researcher at OIST (Okinawa, Japan) to explore how mitotic stress shapes aging. If you’re excited about cell biology, aging, and mechanistic discovery, we’d love to hear from you. More info: www.oist.jp/careers/post... Website: www.oist.jp/research/res...

Cell Proliferation and Gene Editing Unit

Every day, millions of cells divide to sustain essential tissue functions. Errors in this process can lead to developmental disorders or cancer. Our research focuses on the molecular mechanisms of cel...

oist.jp

Last 3 days to apply for this post. Deadline 27/10/25

Aga Gambus@agagambus.bsky.social · 10mo ago

We are looking for a senior technician (can undertake PhD) at Uni of Birmingham (UK) to study chromatin replication and ubiquitylation using Xenopus egg extract. Deadline 28/10/25. Get in touch with me or @m-saponaro.bsky.social for informal inquiries. Please share. www.jobs.ac.uk/job/DOW912/s...

I have a PhD opening in my lab for an exiting project using base editor screens to find novel drug targets. Please help spread the word. candidate.hr-manager.net/ApplicationI...

PhD student position in the Cell Signaling and Cell Cycle group at the Danish Cancer Institute.

The Cell Signaling and Cell Cycle group, headed by Prof. Jakob Nilsson, is looking for a highly motivated and enthusiastic PhD student to establish novel CRISPR

candidate.hr-manager.net

A simple idea for how paclitaxel achieves tumour selectivity: It is better retained inside dense tissue, allowing tumour levels to stay high even after it has cleared the healthy cells. A model that requires testing, but could be used to improve treatments if correct www.biorxiv.org/content/10.1...

A perfusion-based model to explain how paclitaxel achieves tumour-selective killing

Paclitaxel (taxol) is a commonly used chemotherapeutic that stabilizes microtubules to inhibit chromosome segregation during mitosis. Although it is used effectively to treat a wide variety of solid t...

biorxiv.org

“We have economies that need to grow, whether or not they make us thrive; what we need are economies that make us thrive, whether or not they grow.” www.nature.com/articles/d41...

End GDP mania: how the world should really measure prosperity

The obsession with economic output as a measure of human development puts sustainability on the back burner. Researchers can now help to devise better indicators.

nature.com

@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer. Deadline 15th October. Get in touch if you have any questions. Please repost! More details: www.imperial.ac.uk/jobs/search-...

Description

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

imperial.ac.uk

The Garnett Lab is excited to launch DepMap Miner, a new tool to explore cancer dependency data! Built on the Sanger DepMap, the DepMap Miner brings together multi-omic and functional datasets for over 1300 cancer cell models. Start mining data now: dataminer.depmap.sanger.ac.uk

Very excited to post our latest work showing the mitotic stopwatch monitors more than just mitotic delays - it protects against whole genome doubling and cell enlargement. Great work by fantastic postdocs Lindsey and Reece (& student Maria) #PostdocAppreciationWeek www.biorxiv.org/content/10.1...

The mitotic stopwatch limits the proliferation of whole genome doubled cells

Whole genome doubling (WGD) is a frequent event in tumourigenesis that promotes chromosomal instability and tumour evolution. WGD is sensed indirectly due to the presence of extra centrosomes, which a...

biorxiv.org

I've written to Keir Starmer, Kemi Badenoch and Nigel Farage, urging them to join me in condemning Elon Musk's dangerous remarks inciting violence yesterday. As leaders, we must stand together and make clear Musk will face serious consequences for these actions.

Excited to share our lab’s latest preprint! We identify DDIAS as a novel single-stranded DNA-binding component of the TOPBP1–CIP2A complex, which acts in a mitotic DNA damage response pathway to protect chromosome integrity. Short summary below, and read it here: www.biorxiv.org/content/10.1...

DDIAS is a single-stranded DNA-binding effector of the TOPBP1-CIP2A complex in mitosis

DNA double-strand breaks and unresolved DNA replication intermediates are particularly dangerous during mitosis. Paradoxically, cells inactivate canonical DNA repair mechanisms during chromosome segre...

biorxiv.org