Check out this week's episode featuring Dr. Andrew Hogan at @maynoothuniversity.ie! He discusses how #obesity reshapes the immune system and how #GLP1 therapies are transforming treatment. 🎧 Tune in now: https://bit.ly/3T2vFoL

⌛️ 5 days to go! Submit your abstract for our event with @london-immuno.bsky.social here: vist.ly/59p7t

British Society for Immunology@britsocimm.bsky.social · last mo.

📢 Good news! The abstract submission deadline for #LIG26 has been extended to 14 July. There's still time to share your research at this one-day meeting exploring how environmental signals shape immune responses. 📝 Submit and join the conversation: vist.ly/59p7t

In #ScienceSignaling, scientists review the latest research about the four factors that support the fitness of mucosal-associated invariant T (MAIT) cells—and discuss findings identifying nutrient availability as a fifth pillar of MAIT cell fitness. https://scim.ag/3Q4akKj

Environmental regulation of mucosal-associated invariant T cells: Adding food for thought

Nutrients are important environmental factors that affect the functional responses of MAIT cells to challenge.

scim.ag

Review @andyhogan82.bsky.social @maynoothuniversity.ie Nutrients are important environmental factors that affect the functional responses of MAIT cells to challenge www.science.org/doi/10.1126/...

🚨 New Publication Alert - out now in @science.org - We outline the environmental regulators of MAIT cells including the nutrients they need - with them coming into focus in cancer this is sure to be important - read it here doi.org/10.1126/scis...

Environmental regulation of mucosal-associated invariant T cells: Adding food for thought

Nutrients are important environmental factors that affect the functional responses of MAIT cells to challenge.

doi.org

Join us in London this September to explore how environmental signals shape immune responses, with speakers including Yasmine Belkaid, Petter Brodin and more. 📅 Abstract deadline: Monday 29 June 2026 🎟️ Register early to save! Learn more: vist.ly/54ad6

Delighted to share our latest paper out today - led by @ardeena-berisha.bsky.social - we show that we can boost the anti-cancer activity of human MAIT cells by getting them to use lactate & also directing them using bi-specific engagers as a proof of concept academic.oup.com/jimmunol/art...

Lactate conditioning reprograms mucosal-associated invariant T cell metabolism boosting effector function

Abstract. Mucosal-associated invariant T (MAIT) cells are unconventional T cells, which upon activation can display potent cytotoxic and cytokine-producing

academic.oup.com

Delighted to see over review and concept on the cover of this month's @cp-trendsendomet.bsky.social where we cover GLP-1s & SGLT2i as anti-inflammatory agents- co-authored with @nickjonesimmuno.bsky.social

📻 Listen back: Prof Andy Hogan, Dept of Biology, was featured in the Laura Dowling Experience podcast where he discussed his work in immunology, obesity, immune health, GLP-1 therapies, his early life plus much more. open.spotify.com/episode/2ORB...

Dr Andy Hogan on How the Immune System Shapes Your Health

Spotify video

open.spotify.com

🧬 Have you submitted your abstract for #UKimmunomet26? The deadline is approaching in 3 weeks! Join the UK’s leading immunometabolism meeting in NCL for cutting edge research, international speakers & sessions for ECRs. Find out more & register 🔗 https://bit.ly/493uE45

****2-NBDG does not measure glucose uptake**** Just your regular reminder of this fact 😁. See the rigorous proof of this fact in @lindavsinclair.bsky.social 2020 paper. This paper was 6 years ago!! Stop using 2NBDG to measure glucose uptake already 🙄 pmc.ncbi.nlm.nih.gov/articles/PMC...

Single Cell Glucose Uptake Assays: A Cautionary Tale

Assays to monitor the metabolic state or nutrient uptake capacity of immune cells at a single cell level are increasingly in demand. One assay, used by many immunologists, employs 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose ...

pmc.ncbi.nlm.nih.gov

My favourite meeting! Brilliant science and even better community!! Recommend for all from new PhD to old Profs

Pallett Lab UCL@pallettlab.bsky.social · 7mo ago

Don't miss out on your chance to attend "Fuelling the immune response IV: #UKimmunometabolismMeeting2026" Those that have joined before will know these are fantastic meetings providing an open & productive forum to discuss really cool science 📆16-17th April www.immunology.org/events/fuell...

Registrations are now open for 'Fuelling the immune response', the 4th UK immunometabolism meeting, led by the BSI Immunometabolism Affinity Group. Join us in Newcastle on 16 and 17 April 2026 for cutting edge immune metabolism research #UKimmunomet26 Register here: https://bit.ly/493uE45

Seeking a junior scientist for scRNA-seq analytics in Cologne or remotely. If terms like Seurat, DimPlot, or ggplot2 spark recognition—or curiosity—you might be a fit.Flexible $$ Contract, Part time, MSc-to-PhD transition, or PhD project possible. Please feel free to reach out: triffelm@uni-koeln.de

Studies of T cell acute lymphoblastic leukemia reveal that canagliflozin possesses potent anti-leukaemic effects underpinned by proliferative defects, cell cycle disruption and apoptosis, actions synergized by restriction of serine and glycine www.sciencedirect.com/science/arti...

Canagliflozin synergises with serine restriction mediating anti-leukaemic effects in T-cell acute lymphoblastic leukaemia

T-cell acute lymphoblastic leukaemia (T-ALL) is a haematological malignancy commonly driven by NOTCH1 activating mutations. A concomitant feature asso…

sciencedirect.com

Compelling metabolic benefits of semaglutide over 30 weeks in patients with schizophrenia Rxed with second-generation antipsychotic agents jamanetwork.com/journals/jam...

Semaglutide Treatment of Antipsychotic-Treated Patients With Schizophrenia, Prediabetes, and Obesity

This multicenter randomized clinical trial assesses the effect of once-weekly administration of the glucagon-like peptide-1 receptor agonist semaglutide in adults treated with second-generation antips...

jamanetwork.com

MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines www.science.org/doi/10.1126/... @sciimmunology.bsky.social @aliamini419.bsky.social @thelucygarner.bsky.social @nprovine.bsky.social

The new metabolic medicines #T2D #obesity and #inflammation www.cell.com/trends/endoc...

Repurposing metabolic drugs as anti-inflammatory agents

Dysregulation of bodyweight systemic metabolism is intrinsically linked to an inflammatory phenotype, with each underpinning the other. Over the past decade, new classes of drug, such as glucagon-like...

cell.com

Delighted to share our new review in @cp-trendsendomet.bsky.social on Repurposing metabolic drugs (GLP-1s & SGLT2s) as anti-inflammatory agents! Thanks to @nickjonesimmuno.bsky.social for this joint effort doi.org/10.1016/j.te...

Delighted to have our latest paper now online in Stem Cell Research & Therapy rdcu.be/ezDs3 Congrats to lead co-first authors @courteney.bsky.social @laurabitterlich.bsky.social and collaborators @james Ankrum @andyhogan82.bsky.social @maynoothuniversity.ie

This was a labor of love requiring lots of teamwork over years, repeating in 3 locations! Thanks to all the lab over the years, giving their time generously to this team project, & our wonderful collaborators. The source of fat matters for anti-tumor immunity 🐄🐖🧈🌴🫒🥥 www.nature.com/articles/s42...

The source of dietary fat influences anti-tumour immunity in obese mice - Nature Metabolism

This study shows that animal-based high-fat diets accelerate tumour growth and impair anti-tumour response to melanoma in obese mice, whereas plant-based high-fat diets do not.

nature.com

🦠 New research shows obesity disrupts dendritic cell responses to viruses by impairing cytokine production & metabolism - helping explain higher infection risk. 📖 Read the open-access study: https://bit.ly/40kBiiH By @andrea-woodcock.bsky.social‬ et al. #Immunology

Couple of months into our new social media experiment and we are blown away by the engagement - over 2.6 million views on TikTok alone and the daily feedback both online and in person has been so positive and supportive! A whole new way of spreading research based info vm.tiktok.com/ZNdSrMT71/

Our lab @obesityimmunology.bsky.social is looking to support a stellar scientist in their application to the Marie-Sklodowska-Curie European or Global Fellowship to join us to unravel the impact of obesity on the immune system - DM or email andrew.e.hogan@mu.ie for details europa.eu/!B8hjh3

Choose Europe: advance your research career in the EU

Move to the EU as a researcher or scientist. Discover how to relocate, find jobs and funding, and enjoy Europe's excellent quality of life.

europa.eu

www.tiktok.com/@osheahoganl...

Is obesity a contagious disease 🤔 #research #sugar #obesity #obesityawarness #immunology #study #addiction

TikTok video by O’Shea Hogan Labs

tiktok.com

En route home from @kingscollegelondon.bsky.social after 2 days of fantastic science chats! Huge thanks to @peruchalab.bsky.social for the invite and hospitality. Hopefully lots of new collaborations

Obesity is associated with increased susceptibility to infection, which may be due to obesity-induced immune dysregulation. The latest article exchange highlight from @discovimmunol.bsky.social looks at dendritic cell responses to Sendai Virus in a mouse model of diet-induced obesity.

Obesity drives dysregulation in DC responses to viral infection

AbstractIntroduction. Obesity is a worldwide epidemic, with over 1 billion people worldwide living with obesity. It is associated with an increased risk of

academic.oup.com

ICB - the journal@immunolcellbiol.bsky.social · 2y ago

January's article exchange highlight from @discovimmunol.bsky.social investigates evolutionary advantages of PD-1, which could help uncover mechanisms of immune-related adverse events associated with PD-1 blockade #immunotherapy academic.oup.com/discovimmuno...

More evidence for GLP-1 medications in limiting rates of cancer. "The findings of this cohort study suggest that GLP-1RAs are associated with reduced risk of developing several hematologic cancers in patients with T2D" jamanetwork.com/journals/jam...

Hematologic Cancers Among Patients With Type 2 Diabetes Prescribed GLP-1RAs

This cohort study compares the risks of developing different hematologic cancers in patients with type 2 diabetes treated with glucagon-like peptide–1 receptor agonists (GLP-1RAs) compared with metfor...

jamanetwork.com

At the Irish Coalition for People living with Obesity's (ICPO) book launch - a child friendly non-stigmatizing introduction to what is Obesity - great initiative