Bijvoet Centre
@bijvoet-centre.bsky.social
The Bijvoet Centre of Utrecht University studies how life works at the smallest possible level, that of the atoms and molecules of which all life is built. Visit us: http://uu.nl/science/bijvoet
The @instruct-eric.bsky.social Biennial Structural Biology Conference #IBSBC2026 is underway today in Brussels Thanks to our hosts @jansteyaert.bsky.social and his team at the highly successful #Nanobodies4Instruct facility Learn all about is and apply to access instruct-eric.org
We are excited to be at our annual Bijvoet Symposium today, for a day filled with exciting structural biology presented by our PhD students and postdocs!
Today we celebrated, in the presence of the Dutch minister of Education, Culture and Science, Rianne Letschert, the NWO Roadmap grants, including the BioBeyond_NL and EMPower grants investing in infrastructures for biology beyond the genome and for electron microscopy in the Netherlands!
Next Tuesday, Jose Luis Vilas of @cnb-csic.bsky.social will be delivering an @sbgrid.bsky.social webinar on image processing using the Scipion software package! For more info and to sign up, please see our website:
SBGrid Software Webinar - Image processing made simple with scipionTomo
<p>SBGrid is happy to present a software webinar. This session will be delivered by Jose Luis Vilas, Ph.D., who is an Investigator at the National Biotechnology Center, CSIC in Spain. This session…
instruct-eric.org
We are happy to be hosting Sander van Kasteren, of Leiden University, @unileiden.bsky.social, for a Bijvoet Seminar! Sander combines organic synthesis (click chemistry) and dendritic cell biology to study and manipulate the uptake and routing of antigens in dendritic cells.
New OpenFold3 preview out! (OF3p2) It closes the gap to AlphaFold3 for most modalities. Most critically, we're releasing everything, including training sets & configs, making OF3p2 the only current AF3-based model that is functionally trainable & reproducible from scratch🧵1/9
We are happy to be hosting John Christodoulou, of University College London, @ucl.ac.uk, today for a Bijvoet Seminar entitled "Structural investigations of protein folding on the ribosome".
With sadness we share the passing of em. prof. dr. Hans Vliegenthart, founder of the Bijvoet Centre for Biomolecular Research at Utrecht University. His scientific legacy will continue to inspire. In memoriam: www.uu.nl/en/news/in-m...
In memoriam: Hans Vliegenthart
In memoriam: prof. dr. Hans Vliegenthart (April 7, 1936 – February 12, 2026)
uu.nl
We are happy to be hosting David Dulin, @dulinlab.bsky.social, of @vuamsterdam.bsky.social today, for a Bijvoet Seminar entitled "Leveraging high-throughput magnetic tweezers to investigate coronavirus replication at the single-molecule level".
The Dutch Research Council (NWO) announced large investments in 11 (inter)national research infrastructures this week, and we are very happy that includes investments in our electron microscopy and mass spectrometry facilities, through projects EMPower and BioBeyond-NL: www.nwo.nl/en/news/nati...
National Roadmap: NWO invests 197 million euro in eleven Large-Scale Research Infrastructures | NWO
Eleven consortia from various scientific disciplines are set to launch projects of great value to science. But also to the economic and social prosperity of the Netherlands. For example, a consortium led by TU Delft will start work on a detailed virtual model of the Dutch energy system. In another project, a consortium of UMC Utrecht is developing an MRI scanner that can scan people in motion.
nwo.nl
We are happy to be hosting Alex Volkov of the Vrije Universiteit Brussel today, for a Bijvoet Seminar entitled "When chemistry meets biology: a travel to the protein multiverse".
Today, the Dutch nodes of the European Life and Medical Science Research Infrastructures discuss their strategy and sustainability for the future at @naturalis.bsky.social in Leiden. We are representing @instruct-eric.bsky.social and structural biology.
Only a few days left to apply for our EMBO course with a great lineup of speakers and tutors! Please feel free to RT! Course website: meetings.embo.org/event/25-bio... Organizers: myself, @amjjbonvin.bsky.social @bioinfo.se @lindorfflarsen.bsky.social Location: www.ibg.edu.tr
Automated detection of macromolecules in cryo-ET data of cellular samples is challenging. Here, we introduce "pytom-match-pick", a GPU-accelerated, open-source interface that improves the efficiency and accuracy of macromolecule detection in cellular contexts: www.sciencedirect.com/science/arti...
pytom-match-pick: A tophat-transform constraint for automated classification in template matching
Template matching (TM) in cryo-electron tomography (cryo-ET) enables in situ detection and localization of known macromolecules. However, TM faces cha…
sciencedirect.com
The artists from Sensu have worked with @thermofishersci.bsky.social and made this beautiful video on the applications of structural biology: www.youtube.com/watch?v=m3QA... Check out our YouTube channel for videos we made with Sensu about our work: www.youtube.com/@BijvoetCenter
Launching Thermo Fisher Scientific's Krios 5 Cryo-TEM | A New Era in Electron Microscopy
YouTube video by Sensu
youtube.com
Indeed I'm happy to be here! Looking forward to great science 💪🏼
We are happy to host, on behalf of the Netherlands, the Council meeting of Instruct-ERIC (@instruct-eric.bsky.social), the European Research Infrastructure Consortium for structural biology. If you are interested in accessing state of the art structural biology technology, see instruct-eric.org.
We are very happy to have Christoph Müller from the EMBL (@embl.org) as the final speaker of the joint session of Instruct-ERIC (@instruct-eric.bsky.social) and the Bijvoet Centre at the 2025 Bijvoet Symposium!
Delighted to be in Utrecht to learn from our users in the Netherlands, we can always do better!! @utrechtuniversity.bsky.social @nkinl.bsky.social @necen.bsky.social
Instruct-ERIC@instruct-eric.bsky.social · last yr.Delighted to kick off the Instruct-ERIC Minisymposium I’m the Bijvoet Annual meeting in Utrecht today, with @claudialen.bsky.social! instruct-eric.org/centres/inst... @nkinl.bsky.social @utrechtuniversity.bsky.social @unileiden.bsky.social
The next speaker this afternoon is Michael Leung of @hubrechtinstitute.bsky.social, who conducted Cryo-EM studies at NeCEN in @unileiden.bsky.social through Instruct! instruct-eric.org/centre/necen...
Since this month, Eva Bertosin (@thedneva.bsky.social) has joined the Bijvoet Centre, bringing her expertise on biophysics and DNA origami. Welcome Eva!
Beautiful and inspiring talk by Sheena Radford of the @radford-lab.bsky.social at the Astbury Centre for Structural Molecular Biology (@astbury-bsl.bsky.social) from the University of Leeds (@universityofleeds.bsky.social) at our annual Bijvoet Symposium!
Great to have almost the entire Bijvoet Centre together for our 2025 Bijvoet Symposium! Looking forward to a lot of exciting science!
The manuscript describing the new modular version of HADDOCK is finally available as a preprint! The result of a team work over several years, supported by @bioexcelcoe.bsky.social @bijvoet-centre.bsky.social @esciencecenter.bsky.social - www.biorxiv.org/content/10.1...
Simultaneous polyclonal antibody sequencing and epitope mapping by cryoEM and mass spec: how far can we go? Check out the final version of our paper in eLife: elifesciences.org/articles/101...
We are very happy to host Max Bonomi (@bonomimax.bsky.social) from the Institute Pasteur (@pasteur.fr) for a Bijvoet Seminar about structural and dynamic biology with integrative approaches.
#GBMLunch on April 23! Speaker: Tzviya Zeev Ben Mordeha @tzviyazbm.bsky.social from @bijvoet-centre.bsky.social Title: Cryo-EM single particle analysis meets cryo-ET at the sperm tail Chair: Cristina Paulino from @uniheidelberg.bsky.social Organized by the GBM Study Group "Structural Biology"
In this recent publication, we used an Orbitrap Astral mass spectrometer to rapidly analyze plasma glycoproteins, identifying over 3000 glycoPSMs in 40 minutes, with potential for high-throughput clinical applications: www.nature.com/articles/s41...
In-depth plasma N-glycoproteome profiling using narrow-window data-independent acquisition on the Orbitrap Astral mass spectrometer - Nature Communications
While DIA has advanced standard proteomics, its application in glycoproteomics has remained limited. Here, the authors present an optimized narrow-window DIA method for N-glycopeptides, nGlycoDIA, ena...
nature.com
Interested in advanced therapeutics such as mRNA? See the latest work of Evolène Deslignière, doi.org/10.1016/j.om..., in collaboration with Pfizer, using innovative mass spectrometry & photometry @bijvoet-centre.bsky.social to obtain precision measurements on mRNA purity & structural integrity
