Maria Bohnert Lab

@bohnertlab.bsky.social

Cell Biology and Biochemistry lab at University of Münster. We study lipid droplets, lipid metabolism, organelle communication.

Hey #nucleus nerds, the JCS Special Issue on the Cell Biology of the Nucleus is now live! This was a pleasure to co-edit with Megan King @luskinglab.bsky.social.

Journal of Cell Science@jcellsci.bsky.social · last mo.

Our Special Issue: Cell Biology of the Nucleus is complete Explore our Toc: journals.biologists.com/jcs/issue/13... Our cover image shows the posteriorly positioned nuclei (Nup50-mCherry - pink) of notochord cells in Ciona embryos. See article by Peng et al. journals.biologists.com/jcs/article/...

JCS Cover: Posterior nucleus positioning in Ciona notochord cells. Co-expression of hCD4–eGFP (green, cell boundary) and Nup50–mCherry (pink, nuclei) in notochord cells in Ciona embryos. The cells and the nuclei are 3D reconstructed and highlighted by Imaris software. See article by H. Peng et al. (jcs264699).

Special Issue on Cell Biology of the Nucleus 
Guest Editor: Abby Buchwalter

I'm delighted to present TWO new preprints from my lab, led by @mczanellati.bsky.social and @sherryhsu.bsky.social, about how #organelles remodel throughout #NeuronalDifferentiation. Check out the threads about their papers below:

Sarah Cohen@cohenlaboratory.bsky.social · 6mo ago

Cells come in many shapes and sizes, with diverse physiological functions. But how do #organelles and their interaction networks remodel during #differentiation of stem cells into different cell types? Here’s what we discovered about neuronal differentiation: 1/13

Fat storage in the body relies on specialized structures called lipid droplets. In a new Science study, researchers identified the microprotein adipogenin as a regulator of adipocyte lipid droplet size, revealing a key mechanism in lipid homeostasis. Learn more this week: https://scim.ag/4nFEGO7

Lipid droplet growth is orchestrated by the seipin complex, which provides a structural platform for droplet nucleation and expansion. The microprotein adipogenin fine-tunes seipin’s conformation, remodeling its architecture to regulate lipid storage capacity. This modulation results in the formation of fewer but larger lipid droplets, revealing a key mechanism in lipid homeostasis.