Borrell Lab
@borrell-lab.bsky.social
Neurogenesis and cerebral cortex expansion in development and evolution
🎉 ¡Enhorabuena a @nietoangela.bsky.social, @bertalsl.bsky.social y Katia Sofía Illescas (@borrell-lab.bsky.social) por las ayudas de @contracancerinv.bsky.social para impulsar sus proyectos de investigación! Gracias por seguir apoyando la investigación oncológica👏 in.umh-csic.es/es/el-instit...
These results instigated our search for Cajal-Retzius cells across vertebrates; the paper is now in @currentbiology.bsky.social with a nice perspective piece from @borrell-lab.bsky.social, adding to @fredcauseret.bsky.social's previous piece in Development 🧵4/7 www.sciencedirect.com/science/arti...
Evolutionary origins and transcriptomic innovations of vertebrate Cajal-Retzius cells
Evolutionary changes in cortical development were instrumental in the emergence of the mammalian neocortex. Cajal-Retzius cells, a transient neuron ty…
sciencedirect.com
Maria Antonietta Tosches@matosches.bsky.social · last yr.Excited to share our latest work on brain evolution, where we dive into the evolution of Cajal-Retzius cells! If you are interested in cell type evolution and cerebral cortex evo-devo, please read on… www.biorxiv.org/content/10.1... 🧵 1/7
Today we had the pleasure of hosting Dr. Fenna Krienen from @princetonneuro.bsky.social @princeton.edu at our #SeminarsIN with her talk: “Spatially-resolved genetic programs in primate brains”. A fantastic lecture, thank you! 👏👏 @csic.es @dicv.csic.es @umh.es @guillelbendito.bsky.social
Our paper is out in Developmental Biology! It's part of a special issue on Forebrain Development. Mouse KO of Togaram1, a Joubert Syndrome gene, has defects in forebrain morphogenesis and neurogenesis. 🐭🧠🧪 #cilia #devbio #cellbio www.sciencedirect.com/science/arti...
Microtubule binding protein Togaram1 is required for proper development of mammalian forebrain and neural primary cilia
Proper forebrain development relies on precise spatial and temporal control of early neural stem cell (NSC) proliferation and later neurogenesis. Brai…
sciencedirect.com
👏 ¡Enhorabuena a Eduardo Fernández Ortuño @edufdzortu.bsky.social, que realizó su doctorado en el @borrell-lab.bsky.social del @neuroalc.bsky.social, por ser finalista local del concurso #HiloTesis! @umh.es 🔗 comunicacion.umh.es/2026/05/29/e...
Leading international experts in #mechanobiology gathered in Sant Joan d’Alacant for the ‘Mechanobiology of Physiological Systems’ conference, to share and discuss the latest breakthroughs in this rapidly advancing field🔬🧠 Read more👇 in.umh-csic.es/en/el-instit... @csic.es @dicv.csic.es @umh.es
Check out the fantastic line-up for our Spring Meeting on June 5th including @steinaerts.bsky.social, @borrell-lab.bsky.social, @silvianeuro.bsky.social, Simon Hippenmeyer, @idoiaeu.bsky.social and Jin-Wu Tsai. Registration & abstract submission deadline May 15th. www.bscdb.be/spring-meeting
Spring Meeting 2026 | Belgian Society for Cell and Developmental Biology
bscdb.be
⏳ Good news! Deadline extended to May 1st Join leading researchers exploring how mechanical forces shape development and physiology 👉 mechano2026.umh.es @csic.es @dicv.csic.es @umh.es @painchannels.bsky.social @borrell-lab.bsky.social @embo.org @naniontech.bsky.social @3brainag.bsky.social
PhD defended! 🎓 After years studying the developmental origins of pediatric brain tumors, I’m incredibly grateful to my supervisor Dr. Víctor Borrell @borrell-lab.bsky.social and to all the mentors, colleagues, friends and family who supported me along the way. On to the next chapter!
Instituto de Neurociencias CSIC-UMH@neuroalc.bsky.social · 7mo ago🎉 Enhorabuena a la recién nombrada hoy Dra. Anna Prieto Colomina @annaprico.bsky.social por su defensa de #TesisIN y felicitaciones a su director de tesis, el Dr. Víctor Borrell @borrell-lab.bsky.social 🎉 @umh.es @csic.es @dicv.csic.es
🎉 Enhorabuena a la recién nombrada hoy Dra. Anna Prieto Colomina @annaprico.bsky.social por su defensa de #TesisIN y felicitaciones a su director de tesis, el Dr. Víctor Borrell @borrell-lab.bsky.social 🎉 @umh.es @csic.es @dicv.csic.es
Today, the IN Developmental Neurobiology Scientific Department has offered a new scientific seminar featuring the presentations of researcher Francisco Tejedor and PhD student Enrico Negri (📷) @borrell-lab.bsky.social 👏👏👏 @csic.es @dicv.csic.es @umh.es
Dejamos atrás el mes más largo del año😅y damos la bienvenida a #febrero con esta imagen de Emily Wilson @glb-lab.bsky.social #SciencePhoto_IN 🔬🧠 #Ciencia @csic.es @dicv.csic.es @umh.es
🎉 Enhorabuena al recién nombrado hoy Dr. Eduardo Fernández Ortuño @edufdzortu.bsky.social por su defensa de #TesisIN y felicitaciones a sus directores de Tesis, el Dr. Víctor Borrell y el Dr. Adrián Cárdenas Castelló @borrell-lab.bsky.social 🎉 @umh.es @csic.es @dicv.csic.es
Dynamic subtype- and context-specific subcellular RNA regulation in growth cones of developing neurons in the cerebral cortex. rdcu.be/eXuwg
Dynamic subtype- and context-specific subcellular RNA regulation in growth cones of developing neurons of the cerebral cortex
Nature Neuroscience - Distinct neuron subtypes compartmentalize specific functions by differentially localizing and translating specific RNAs. This work identifies dynamic subtype- and...
rdcu.be
Today we had the pleasure of hosting Dr. Bassem Hassan @hassanbraindevlab.bsky.social from @institutducerveau.bsky.social at our #SeminarsIN with his talk: “Temporal control of neurogenesis” A fantastic lecture, thank you! 👏👏 @csic.es @dicv.csic.es @umh.es @borrell-lab.bsky.social
We have the pleasure of welcoming Dr Bassem Hassan @hassanbraindevlab.bsky.social from @institutducerveau.bsky.social tomorrow at #SeminarsIN 🙌 He is a world leader in the study of genetic regulation of brain development. Don’t miss it! @borrell-lab.bsky.social @csic.es @dicv.csic.es @umh.es
The importance of model organisms for research and training www.nature.com/articles/s41...
Reaffirming the value of model organisms in training scientific minds - Nature Cell Biology
As biomedical research prioritizes human models and translational promise, classic model organisms are increasingly dismissed. Here we argue that they have a lasting value, both in enabling discovery and in cultivating scientific thinking, by training researchers in systems reasoning, integrative thinking and independent inquiry.
nature.com
I am thrilled to share our latest story led by the incredibly talented Brooke D’Arcy and Camila Musso. We discover a rich world of local gene expression in radial glia, essential neural and glial precursors, and develop a new method for sub-cellular mRNA manipulation. www.biorxiv.org/content/10.1...
Interested in the mechanisms of neurogenesis, and how they might converge/differ across species, regions, and life epochs? Check this out, wonderful location and great science! Please RT neuro-unige.ch/news/csf-mee...
👏 Congrats to @neuroalc.bsky.social researchers named in Stanford’s ranking of the world’s most cited scientists: Carlos Belmonte, @borrell-lab.bsky.social , @jlerma1.bsky.social , Salvador Martínez, @nietoangela.bsky.social & @neuroviana.bsky.social , outstanding global impact in neuroscience!
📅 Hoy es el Día Mundial de la Investigación en #Cáncer, una jornada para visibilizar la ciencia frente a este conjunto de enfermedades 🔬 Te contamos algunas de las investigaciones oncológicas del #CSIC para mejorar la salud de las personas #WorldCancerResearchDay 🧵👇
Ever wondered how robust cellular identity is to external perturbations? Here we disrupt cellular environmnent in vivo and in vitro, and find cell population specific sensitivities. Environment sculpts development yes, but not all cells are made of the same wood. www.science.org/doi/10.1126/...
Cell-extrinsic controls over neocortical neuron fate and diversity
Cell-extrinsic cues are key for neocortical cell identity and diversity.
science.org
1) I am delighted to present this terrific tour de force research conducted by my post-doc Dr. Gayani Senevirathne @gayani.bsky.social and published today in Nature - www.nature.com/articles/s41...
The evolution of hominin bipedalism in two steps - Nature
The human pelvis exhibits distinct spatiotemporal ossification patterns and an ilium cartilage growth plate that is shifted perpendicularly compared with those of other mammals and non-human primates—...
nature.com
This therapy builds on research from Carlos Belmonte, @neuroviana.bsky.social and colleagues, who showed how corneal cold receptors drive tear production and identified TRPM8 as a target. Once again showcasing the international nature of scientific progress.
Join us if you want to learn about #microglia!
Sociedad Española de Bioquímica y Biología Molecular (SEBBM)@sebbm.bsky.social · last yr.🗓️El próximo 16 de septiembre a las 16h "Webinar Grupo Neurobiología Molecular" coordinado por @pgonzalezrodriguez.bsky.social 🗣️ @sierralab.bsky.social “Brain scavengers: microglial phagocytosis in health and disease ✍️ https://f.mtr.cool/fawelesych
Sharing our newest study led by the incredibly talented @federicamosti.bsky.social investigating new molecular mechanisms of human brain development. We discover a human-specific enhancer HAR1984 that influences chromatin looping to promote cortical size and folding! www.biorxiv.org/cgi/content/...
My quote of the day I am patient with stupidity but not with those who are proud of it. Edith Sitwell