It's that time of year again... APS fall awards season is upon us!🎊 Check out our website for everything you'll need to get started—info on available awards, how to apply (or nominate others,) important deadlines and more: https://ow.ly/taC650ZOpKn #ProfDev #ScienceAwards #Physiology 🧪 📷: iStock

I am very happy to share our new preprint on #Drosophila muscles. @tiaramuld.bsky.social discovered flies have a tremendous ability to remodel their muscles after massive damage. www.biorxiv.org/content/10.6...

Evidence of complete myofibril remodeling after severe damage in adult Drosophila.

Muscle function depends on the ability of myofibrils to withstand and repair mechanical damage, yet how adult muscles remodel damaged myofibrils remains poorly understood. Here, we establish a Drosoph...

biorxiv.org

My MCDB Dept is hiring, again! Assistant Professor Faculty Search. Please Repost! Applications Due Oct 1st We welcome applications from all areas of cellular/molecular biology in prokaryotes, plants, and animals. More information can be found HERE: jobs.sciencecareers.org/job/679540/a...

Assistant Professor - Ann Arbor, Michigan job with University of Michigan - Molecular, Cellular and Developmental Biology | 679540

UNIVERSITY OF MICHIGAN FACULTY POSITION IN CELL & MOLECULAR BIOLOGY AND RELATED FIELDS   The Department of Molecular, Cellular, and Developmental B...

jobs.sciencecareers.org

The Dept. of Biology at the University of San Diego seeks two tenure-track assistant professors for Fall 2027, with experience in cell biology and/or organismal biology (both broadly defined) & strong interest in undergraduate-research mentoring. Please repost! jobs.sandiego.edu/cw/en-us/job...

The Energetic Cost of Building Human Skeletal Muscle https://www.biorxiv.org/content/10.64898/2026.08.17.745156v1

Check these three faculty searches at Yale and join me in New Haven! 1. Experimental neuroscience apply.interfolio.com/190736 2. Computational/Theoretical neuroscience apply.interfolio.com/190740 3. The (new!) Center for Neuroethology and Physiological Plasticity apply.interfolio.com/191722

@myosincity.bsky.social and I are looking to hire a new postdoc this winter! Open to anyone broadly interested in studying how cells generate and interpret mechanical signals. Interested applicants can reach out to me and Jordan directly.

NIH Intramural Research Program is hiring via the Stadtman program. Prospective candidates should feel free to reach out to me, and I will be happy to share my experience both as an applicant and a panel member- we are looking for great new colleagues! irp.nih.gov/careers/nih-...

Vrije Universiteit Amsterdam, 105 participants. Long COVID and ME/CFS muscles had impaired mitochondrial energy production and fewer capillaries for their size, unlike 60 days of bed rest. Inactivity alone did not explain this. www.nature.com/articles/s41...

New preprint from the lab, led by the ever-talented grad student Tessa Lochetto @tlochetto.bsky.social! We find that loss of our favorite phosphatase Pptc7 decreases lean mass, induces skeletal muscle dysfunction, and causes metabolic derangements in adult mice: doi.org/10.64898/202... /1

Sustained loss of Pptc7 triggers variable skeletal muscle dysfunction and diminished body mass through dysregulation of BNIP3

The mitochondrial phosphatase PPTC7 is required to sustain mammalian metabolism, as its global knockout (KO) triggers hypoketotic hypoglycemia and perinatal lethality in mice. However, the extent to w...

doi.org

Excited to share our new paper, now published in Nature Cell Biology! 🎉 We asked a fundamental question in cell biology: How do cells maintain polarity while migrating? Especially how do cancer cells navigate confined spaces? www.nature.com/articles/s41556-026-01981-1

CD44 restricts EGFR mobility to polarize cytoskeletal signalling modules driving bleb-based migration - Nature Cell Biology

Jha et al. show that the transmembrane protein CD44 restricts EGFR mobility to maintain an EGFR–PI3K–Rac gradient during bleb-based cell migration.

nature.com

Out today in PNAS: We show that dynamic "4D" forces can spatially pattern angiogenesis in a PIEZO1-dependent manner. Excitingly, changing force patterns over time enables redirecting sprouting trajectories, forming complex branched geometries: www.pnas.org/doi/10.1073/... #TissueEngineering

We have not one but TWO post-doc opportunities in our group: Molecular and cellular biology of mitochondrial disease models: www.cam.ac.uk/jobs/postdoc... Targeting mitophagy to modulate nuclear-mitochondrial interactions: www.cam.ac.uk/jobs/researc... Apply now!! @ritahorvath.bsky.social

New research from @phdgprotein86.bsky.social reveals structural defects in #mitochondria of #aging kidneys contribute to #oxidativestress & #kindeydisease. See more on the @aging-us.bsky.social paper: mitoworld.org/micos-comple... #UMDF #mitoscientists #mitochondria #mitochondrialdisease #MICOS

MICOS Complex May Contribute to Mitochondrial Decline During Kidney Aging - MitoWorld

Aging kidneys exhibit mitochondrial structural defects, oxidative stress, fibrosis, and altered metabolism. A new study published in Aging Cell suggests that alterations in the mitochondrial contact s...

mitoworld.org

Looking for your next step after a BS/BA or MS in biology, cell biology, biochemistry, or a related field? My NIH lab in Bethesda, MD is looking for a Lab Manager/Technical Specialist. Interested in basic research? Please email me directly or learn about our lab here: irp.nih.gov/pi/justin-ta...

📢 We are looking for a Junior Group Leader to join us at @institutcurie.bsky.social! Having joined the department just over a year ago, I can honestly say that it is an exceptionally stimulating and supportive scientific environment, filled with outstanding colleagues — all in the heart of Paris.

NIH's Stadtman Investigator Program is back in 2026! As a Stadtman tenure-tracker myself, I cannot emphasize how important this program has been to the establishment of our lab in the intramural world. Take a look, ask me any questions you may have, and apply!

🔬 Ever seen a mitochondrion “flicker”? We designed HBmito, a membrane voltage sensor, to catch nanoscale nanoscale electrical spikes in real time—the first optical glimpse of single mitochondrial channels in action. #Mitochondria #CellBiology #Biophysics link.springer.com/article/10.1...

Website is live, registration is open! meetings.embo.org/event/26-mus...

Brendan Evano@brendan-evano.bsky.social · 5mo ago

📧 Organizing committee B. Evano G. Kardon O. Pourquie I. Scionti

🚨 Join us for the EMBO Workshop Muscle development, maintenance & pathology: in vitro models to physiology 🚨 📍 Aghia Pelagia, Greece 📆 11 – 15 October 2026

Excited to share a new collaborative paper with Lena Koslover's team, fueled by @chanzuckerberg.bsky.social Metabolism Across Scales Program 🧪 1/ www.pnas.org/doi/10.1073/...

Diffusive spreading across dynamic mitochondrial network architectures | PNAS

In eukaryotic cells, mitochondria form networks that range from highly fused interconnected structures to fragmented populations of individual orga...

pnas.org

Edward C. T. Waters from @kings-bmeis.bsky.social et al. conducted this recent study where sarcolemmal and mitochondrial #membrane potentials were measured ex vivo and in vivo in the #heart by #pharmacokinetic modelling of [99mTc]sestamibi 🫀 🔎 📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...

MitoAtlas: a Domain-Resolved Spatial Map of the HumanMitochondrial Proteome https://www.biorxiv.org/content/10.64898/2026.04.03.716438v1

1/9 🚨 New paper out in Nature Metabolism! Chapter 2 of our mitochondria zonation story (following our 2024 Nature Communications work). We asked how zonated liver mitochondria adapt when lipid flux surges. 🧵👇 www.nature.com/articles/s42...

PLIN5 phosphorylation orchestrates mitochondria lipid-droplet coupling to control hepatic lipid flux and steatosis - Nature Metabolism

Using single-cell tissue imaging and spatial proteomics to study mitochondria–lipid droplet coupling in hepatocytes, PLIN5 phosphorylation is identified as a mediator of lipid flux and nutrient stress...

nature.com

Mitochondrial lactate venting limits oxidative stress www.cell.com/cell-metabol...

Mitochondrial lactate venting limits oxidative stress

The main function of mitochondria is to generate ATP by oxidizing pyruvate to CO2. Rauseo et al. show that matrix pyruvate is also converted to lactate, which is released to the cytosol via the MPC to...

cell.com

We are hiring POSTDOC now!🚨please repost! Fully-funded 5-year position 👩🏻‍🔬👨‍🔬🧬Looking forward to your application!✉️

It's been a long time since I sat down and enjoyed reading a paper cover-to-cover as much as this. Some cracking work and experiments. www.science.org/doi/10.1126/...

Mechanical loading induces the longitudinal growth of muscle fibers via a rapamycin-insensitive mechanism

mTORC1 does not always hold the key to unlocking the mechanical load-induced growth of skeletal muscle.

science.org

Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy @cellcellpress.bsky.social @aleprigio.bsky.social www.cell.com/cell/fulltex...

Another preprint is out from the Neal Lab! 🎉 Excited to share the first systematic side-by-side comparison of ERAD Derlin paralogs, revealing distinct cellular functions for Derlin-1, Derlin-2, and Derlin-3. www.biorxiv.org/content/10.6...

Bravo Liza, Brendan and colleagues for the elegant work on multiple live imaging strategies to untangle mechanisms of muscular dystrophy! www.nature.com/articles/s41...

Impaired stem cell migration and divisions in Duchenne muscular dystrophy revealed by live imaging - Nature Communications

Using live-imaging in vivo and ex vivo, Sarde et al. show that dystrophic muscle stem cells have precocious differentiation through symmetric divisions and impaired migration, with differential impact...

nature.com