1/ Very excited to share the first publication from my lab! In this work, we developed an efficient strategy to precisely mutate mammalian histone genes in their native genomic context using CRISPR prime editing: www.nature.com/articles/s41...

Identifying critical lysines in mammalian histone H3 with high-throughput CRISPR prime editing - Nature Genetics

This study uses a precise and efficient clustered regularly interspaced short palindromic repeats (CRISPR) prime editing system to substitute lysine residues in histone H3, individually or in combinat...

nature.com

Working on stem cell biology? Our expert Academic Editor, Aryeh Warmflash (@warmflashlab.bsky.social), handles articles on this topic so send your article our way. It's FREE to publish in JCS and we're not-for-profit. Find out more: journals.biologists.com/jcs/pages/re... #stemcells #ISSCR2026

New in @dev-journal.bsky.social: how tissue shape tells cells what to become Using human stem-cell neuruloids, we show how that physical boundaries encode positional information that drives cell fate patterning in a model of trunk formation A thread 🧵 journals.biologists.com/dev/article/...

Boundary constraints can determine pattern emergence

Summary: A reaction-diffusion mechanism recapitulates pattern emergence in an in vitro model of neuromesodermal progenitors under a variety of boundary and geometrical perturbations.

journals.biologists.com

You don't know what you've got 'til it's gone... A good read, on the importance of curiosity driven research www.nature.com/articles/s42...

Discovery is not the opposite of application - Nature Reviews Physics

Restructuring research funding as a choice between discovery and application gets the economics wrong, the evidence wrong and the people wrong.

nature.com

Beautiful piece on how field-specific journals with high ethical standards, such as Development, don’t try to « Game » the impact factor system - and practical steps to move away from this inherently flawed metric as a researcher (see Box 2)

James Briscoe@jamesbriscoe.bsky.social · 2mo ago

As Editor of @dev-journal.bsky.social I get asked "What are you doing about your impact factor?" In our new editorial we say: Ask not what Dev can do for the impact factor. Ask what you can do for Dev's IF The IF is about how we all cite, review & assess each other's work doi.org/10.1242/dev....

Yet another important benefit of having not-for-profit publishers within the scientific publisher ecosystem. They can do interesting (sometimes risky) experiments, testing innovations that aim to benefit the scientific community rather than enriching shareholders. Up with this sort of thing!

Daniel Gorelick@danielgorelick.bsky.social · 2mo ago

Paying peer reviewers works. Expanded Fast & Fair experiment @biologyopen.bsky.social: • 5.5 vs 37.7 working days to decision with reviews • ~3 vs ~9 reviewer invitations per manuscript • no reduction in editor-assessed review quality • similar acceptance rates www.biorxiv.org/content/10.6...

SO INTERESTING! #PaperThemeTune: Careful With That Axolotl Eugene, by Pink Floyd www.youtube.com/watch?v=7RnF...

Pink Floyd - Careful With That Axe, Eugene (Live at Brighton Dome)

YouTube video by Pink Floyd

youtube.com

Wouter Masselink@woutermasselink.bsky.social · 2mo ago

🚨 New preprint 🚨 Massive shoutout to first author @abinagui.bsky.social !!! The common view is that regenerative competence declines with age. We challenge this idea by showing that axolotl tail regenerative competence is emerges during a defined embryonic window. www.biorxiv.org/content/10.6...

This is a wonderful opportunity, open to postdocs too! Together with @rocha-lab.bsky.social we’ll be organising one on “Bridging Scales and Disciplines to Understand Robust Development” next year. More info soon - registration will open in July!

The Company of Biologists@biologists.bsky.social · 2mo ago

Last few days left to submit your idea for a Workshop for our 2028 programme. Send us your proposal by 29 May 2026 at www.biologists.com/workshops/pr... #BiologistsWorkshops

Deadline extended- still time to apply! Please spread the word.

Stem Cell Summer School@stemcellsummer.bsky.social · 3mo ago

Still time to apply! Deadline extended to 25th May! This is an enriching, immersive, interactive week of talks and discussions with leaders in the field. A brilliant oppportunity for PhD students, postdoc, new PIs. See our testimonials: www.stemcellsummerschool.org/testimonials Spread the word!

Developmental biology bringing together regenerative biology, neurobiology, mathematical modelling, evo-devo and much more to Edinburgh! 19-22 April 2027 Save the date!

British Society for Developmental Biology@bsdb.bsky.social · 3mo ago

Save the date! The 2027 BSDB Spring Meeting will take place on 19 - 22 April in Edinburgh. An exciting programme with a fantastic lineup of speakers showcasing developmental biology across scales! More details soon!

that’s Elon Musk FRS

Josiah Mortimer@josiahmortimer.bsky.social · 3mo ago

Nigel Farage tells The Sun's Harry Cole that Elon Musk offered to give Reform loads of money "if we said certain things" and he refused. "I can't be bought." Two things: 1. This is an allegation of attempted bribery. Very serious. 2. It shows the obvious: donors expect something for their money.

Deadline extended- still time to apply! Please spread the word.

Stem Cell Summer School@stemcellsummer.bsky.social · 3mo ago

Still time to apply! Deadline extended to 25th May! This is an enriching, immersive, interactive week of talks and discussions with leaders in the field. A brilliant oppportunity for PhD students, postdoc, new PIs. See our testimonials: www.stemcellsummerschool.org/testimonials Spread the word!

Reminder! Application deadline Friday 8th May

Stem Cell Summer School@stemcellsummer.bsky.social · 5mo ago

We are delighted to announce that we are now open for applications for 2026 summer school Dates: 11th - 18th September 2026 Deadline for applications: 8th May See our website for info on how to apply.. and to check out our stellar speaker list! www.stemcellsummerschool.org/apply 🧪

This video sums up just some of the reasons I feel proud to publish our work in Company of Biologists journals.

The Company of Biologists@biologists.bsky.social · 3mo ago

The Company of Biologists is a not-for-profit publisher that exists to support biologists and inspire biology. This video tells you more about our aims and activities.

“Conferences were much more exciting as a young, early-career researcher, when every contact felt like an instant friend and every new city, a gift” My most recent blog post on the effect of age on travel perceptions occamstypewriter.org/mindthegap/2...

New Pre-Print Alert! Evolving initial conditions: an alternative developmental route to morphological diversity with Shannon Taylor and @jamesehammond.bsky.social www.biorxiv.org/content/10.6...

Reminder! Application deadline Friday 8th May

Stem Cell Summer School@stemcellsummer.bsky.social · 5mo ago

We are delighted to announce that we are now open for applications for 2026 summer school Dates: 11th - 18th September 2026 Deadline for applications: 8th May See our website for info on how to apply.. and to check out our stellar speaker list! www.stemcellsummerschool.org/apply 🧪

Had so much fun at @bsdb.bsky.social a few weeks go and am very excited about all the upcoming stories I saw. Check out the #preprint list I've collated from the meeting, now on @prelights.bsky.social👇 prelights.biologists.com/prelists/bsd... And please do let me know if there are any I missed 👀

BSDB Spring Meeting: Molecules to Morphogenesis - preLights

prelights.biologists.com

preLights@prelights.bsky.social · 4mo ago

From molecules to morphogenesis Discover a curated #preList of preprints presented at the BSDB Spring Meeting @bsdb.bsky.social - highlighting exciting new research in developmental biology Explore this #preprints list prepared by @ingridtsang.bsky.social ⬇️ prelights.biologists.com/prelists/bsd...

Congratulations to the @dev-journal.bsky.social 2025 Outstanding Paper nominations, & special mention to the winner by Yang et al doi.org/10.1242/dev.... For the top three nominations and an interview with the winners see: journals.biologists.com/dev/article/...

Just look at this graph (Fig 5A,B from Koeber et al). Amazing. Congratulations to the Pollard lab and all authors. www.nature.com/articles/s41...

I illustrated my way through the @bsdb.bsky.social Spring Meeting a couple weeks ago - here's my illustrated summary of the conference! I sketched (almost) all the speakers and glimpses of the science that made it such a great few days.

"Why is publishing so expensive?" It's a question I hear all the time, so we at @biologists.bsky.social thought we'd try to dispel some of the myths around publishing economics & provide transparency around our costs. Today, we publish editorials in all 5 of our journals - links in the thread below.

"We want to see the academic publishing industry change in a way that benefits science, not just profits"

Theo@earthowned.bsky.social · 4mo ago

Cancer Research UK is fed up of paying too much for open access publishing so they are completely stopping funding this activity: news.cancerresearchuk.org/2026/04/01/w...

Cancer Research UK is fed up of paying too much for open access publishing so they are completely stopping funding this activity: news.cancerresearchuk.org/2026/04/01/w...

Why we won’t be funding open access publishing any more - Cancer Research UK - Cancer News

The open access movement was bold and promising, but ultimately disappointing. Now is the time to stop and call for a new way to make publishing work…

news.cancerresearchuk.org

The ABC of my fave things in this paper: * ABOLISHING both silencing AND leakiness of SynNotch (check out the DTA-based demo of this 😍) while preserving high efficiency, in pluripotent & differentiating cells * BOOSTING signal during #PUFFFIN neighbour-labelling * CITING Robbie Burns (1786) 🏴󠁧󠁢󠁳󠁣󠁴󠁿

Mattias Malaguti@matt-mala.bsky.social · 4mo ago

Delighted to introduce KELPE: mESCs with two insulated genomic landing pads, which we use to generate new synNotch and PUFFFIN neighbour-labelling lines. They were named after kelpies, creatures from Scottish folklore, and they look pretty on a kelpie micropattern! #DevBio #SynBio

A unique opportunity to lead the most wonderful company in scientific publishing (I might be slightly biased here). The Company of Biologists are searching for a CEO. www.inspiredselection.com/jobs/jo00000...

Chief Executive Officer | Inspired Selection

inspiredselection.com

Huge congratulations to James Briscoe @jamesbriscoe.bsky.social for receiving the 2026 BSDB Waddington Medal, recognising an extraordinary career of discovery, mentorship, and leadership in developmental biology. bsdb.org/2026/03/24/2...

2026 Waddington Medal Winner - James Briscoe - BSDB - British Society for Developmental Biology

We are very pleased to announce that this year’s Waddington medal winner is James Briscoe. His fundamental discoveries have helped shape our understanding of of how morphogens work, and he has played ...

bsdb.org

And the @bsdb.bsky.social Waddington medal goes to... @jamesbriscoe.bsky.social. Could not be more highly deserved, I'm so delighted to hear this 👏

Absolutely beautiful work from @matt-mala.bsky.social and Aisling Fairweather with valiant input from undergraduate student Yana Slavova. This excellent paper deserves an excellent #paperthemetune Anyone got any suggestions?

Mattias Malaguti@matt-mala.bsky.social · 4mo ago

Delighted to introduce KELPE: mESCs with two insulated genomic landing pads, which we use to generate new synNotch and PUFFFIN neighbour-labelling lines. They were named after kelpies, creatures from Scottish folklore, and they look pretty on a kelpie micropattern! #DevBio #SynBio

It's out! Happy to present ITEC, a semi supervised algorithm with an extremely low error rate that can track cells in files of any size (think Terabytes!). We used it in many organisms, including zebrafish, to study how organs form and linked it to gene expression www.biorxiv.org/content/10.6... +🧪