Lydia Daboussi

@daboussi.bsky.social

Assistant Professor @UCLA - Department of Neurobiology. #newPI https://daboussilab.healthsciences.ucla.edu

New preprint from the lab 🥳 We made new knock-in zebrafish 🐟 that fluorescently tag endogenous neurofascins. So now, we can live-image neuronal nfasca/NF186 and glial nfascb/NF155 non-invasively, as nerves, nodes of Ranvier and paranodes develop in vivo 🧵👇 www.biorxiv.org/content/10.6...

Live-imaging of endogenous neurofascins reveals glial adhesion shapes developing nodes of Ranvier

The organisation of myelinated axons into specialised domains is essential for saltatory conduction and depends on the polarised distribution of neuronal and glial cell-adhesion molecules, including n...

biorxiv.org

Holy shit, we're actually getting there. "UCLA researchers develop low-cost blood test to detect multiple cancers and other diseases from a single sample [—] In tests, MethylScan detected about 63% of cancers across all stages and roughly 55% of early-stage cancers." (from April) #ShareGoodNewsToo

UCLA researchers develop low-cost blood test to detect multiple cancers and other diseases from a single sample

The test could offer a more affordable approach to early disease detection.

newsroom.ucla.edu

The costs of international student exclusion will be vast and permanent. It will harm all Conservative Americans and their children; it will harm all Liberal Americans and their children. It is the exact opposite of what our tech-driven economy needs. I summarize my research at @piie.com —>

The US is driving away international students at a long-term economic cost

For generations, students from around the world have fueled universities in the United States, their top destination by far. Those students don't just sustain a $43 billion export industry in higher e...

piie.com

In section G of the RPPR (annual reports to NIH), on foreign involvement, PIs should report all anticipated foreign co-authors on each future paper resulting from the work. For each paper & each co-author, that includes: Name Institution & location Email Describe their contribution to the paper /t

A friend of mine found these three kittens behind a Bay Area gas station. They are tame, vaccinated, and incredibly affectionate. Unfortunately, she's unable to keep them and I'm trying to find them a home. They are at risk of going to a shelter. Bay Area people, are you open to adopting?

Three kittens in a cage. Two are orange and one is black. Three kittens. Two are orange, one is black. They are laying on a stuffed teddy bear. The black kitten in a scarf.The two orange kittens in a scarf.

Our review on glial orchestration of neurodevelopment is online at @cp-devcell.bsky.social! Great fun working with Krissy Sakers and Pat Sheehan from the Eroglu and Schafer labs, and special thanks to first author Krissy for her tremendous work bringing this to fruition! www.cell.com/developmenta...

Glia orchestrate neural circuit development

In this review, Sakers et al. discuss how astrocytes, microglia, and oligodendrocyte lineage cells actively regulate neural circuit formation, refinement, and stabilization. They propose that coordina...

cell.com

☕Mani, Tardif, Rossier et al. show that mechanical stress triggers caveolin-1 release from caveolae, enabling its diffusion in the plasma membrane and interaction with signaling effectors to regulate intracellular signaling. 👉https://rdcu.be/frvPe www.nature.com/articles/s41...

Diffusing caveolin-1 scaffolds regulate mechanosignalling - Nature Cell Biology

Mani, Tardif, Rossier et al. show that mechanical stress triggers caveolin-1 release from caveolae, enabling its diffusion in the plasma membrane and interaction with signalling effectors to regulate ...

nature.com