Yay! Just saw that we got the cover of the August 1 MBoC! Woot! 🎉 Please check out our paper if you are interested in it the tubulin code or early development. www.molbiolcell.org/doi/10.1091/...
Lydia Daboussi
@daboussi.bsky.social
Assistant Professor @UCLA - Department of Neurobiology. #newPI https://daboussilab.healthsciences.ucla.edu
Love science, teaching genetics, and mentoring? There are some great students and faculty at @smithcollege.bsky.social and they are hiring a tenure track assistant professor! Some of my favorite folks in #DevBio are there! www.smith.edu/people/cagne... www.smith.edu/people/micha...
Pls share. Assistant Professor of Biological Sciences - Genetics/Genomics at Smith College. apply.interfolio.com/190342
Very cool paper systematically characterizing dopamine neuron development and striatal arborization in the mouse brain. www.sciencedirect.com/science/arti...
Single-neuron resolution mapping of dopaminergic connectivity across development, adulthood, and degeneration
Individual midbrain dopamine (mDA) neurons exhibit complex morphologies, a feature that may underlie their different functions and disease vulnerabili…
sciencedirect.com
And much praise to the civil servants at NIH making this happen in terrible conditions
The prestigious Miller Research Postdoctoral Fellowship is open! University of California, Berkeley This is a postdoc fellowship with substantial support and independence to be hosted at a lab at Berkeley, reach out with interests! miller.berkeley.edu/nominate-app...
Miller Research Fellowship | Miller Institute for Basic Research in Science
miller.berkeley.edu
Carolyn Ott @hhmijanelia.bsky.social, Jennifer Lippincott-Schwartz & David Breslow @davidbreslowlab.bsky.social explain how recent advances have expanded our models of primary cilia disassemble and discuss emerging roles of altered disassembly in disease. journals.biologists.com/jcs/article/...
Brain vascular aging isn’t a single path. Our new work shows that the aging brain diverges into two states: 🧠 Hypovascular (expected) 🧠 Hypervascular (surprising), with BBB leakage, inflammation and cognitive decline. Our study👇🏻: www.biorxiv.org/content/10.6...
🖤 A message from our Board of Directors. As we begin another year of Black In Neuro, our Board reflects on our journey, the road ahead, and the community that makes it all possible. Thank you for being part of this movement. #BlackInNeuro youtu.be/RtcS0yWinTs?...
Black In Neuro Week 2026 BOD Message
YouTube video by Black In Neuro
youtu.be
Controlled blinking of upconverting nanoparticles - no bleaching means attractive potential as an SMLM probe! www.nature.com/articles/s41...
New preprint from the lab 🥳 We made new knock-in zebrafish 🐟 that fluorescently tag endogenous neurofascins. So now, we can live-image neuronal nfasca/NF186 and glial nfascb/NF155 non-invasively, as nerves, nodes of Ranvier and paranodes develop in vivo 🧵👇 www.biorxiv.org/content/10.6...
Live-imaging of endogenous neurofascins reveals glial adhesion shapes developing nodes of Ranvier
The organisation of myelinated axons into specialised domains is essential for saltatory conduction and depends on the polarised distribution of neuronal and glial cell-adhesion molecules, including n...
biorxiv.org
mesmerizing!!
Happy #FluorescenceFriday! This is a Warhol (or Whirlhol 😉) inspired montage of a micrograph of cardiac tissue from a P3 🐭. The image shows SHH-producing cells in a whirl pattern across the 🫀 (lower left to upper right). 🔬 by @christinaadaly.bsky.social #DevBio 🧪 👩🔬
Holy shit, we're actually getting there. "UCLA researchers develop low-cost blood test to detect multiple cancers and other diseases from a single sample [—] In tests, MethylScan detected about 63% of cancers across all stages and roughly 55% of early-stage cancers." (from April) #ShareGoodNewsToo
UCLA researchers develop low-cost blood test to detect multiple cancers and other diseases from a single sample
The test could offer a more affordable approach to early disease detection.
newsroom.ucla.edu
Excited to share my postdoc paper from the @lyons-lab.bsky.social Our question: what controls axon diameter? It varies >100-fold between neurons, shapes signal speed & myelination, and changes in disease. Yet very little is known about what regulates it. 🧵 journals.plos.org/plosbiology/...
A high-resolution phenotypic screen identifies regulators of CNS axon diameter in zebrafish
Axon diameter is important for action potential conduction speed, but what molecular pathways influence this neuronal property? This study reports a high-resolution imaging-based chemical screening pi...
journals.plos.org
The costs of international student exclusion will be vast and permanent. It will harm all Conservative Americans and their children; it will harm all Liberal Americans and their children. It is the exact opposite of what our tech-driven economy needs. I summarize my research at @piie.com —>
The US is driving away international students at a long-term economic cost
For generations, students from around the world have fueled universities in the United States, their top destination by far. Those students don't just sustain a $43 billion export industry in higher e...
piie.com
In section G of the RPPR (annual reports to NIH), on foreign involvement, PIs should report all anticipated foreign co-authors on each future paper resulting from the work. For each paper & each co-author, that includes: Name Institution & location Email Describe their contribution to the paper /t
Orangutan mothers take orangutan infants to playdates. www.biorxiv.org/content/10.6...
Maternal ranging strategies facilitate offspring social play at energetic cost in the most solitary ape
In most vertebrates, social play among peers is considered essential for behavioral development. Yet in solitary species bearing single offspring, opportunities for social play are inherently scarce. ...
biorxiv.org
Please share! This fully-funded postdoc position at the UCLA La Kretz Center allows candidates to design their own projects in California conservation, and offers mentorship from both academics and conservation practitioners. drive.google.com/file/d/1K2Qi...
LKC 2027 Postdoctoral Fellowship.pdf
drive.google.com
Judge rules OMB can’t retroactively nix grants based on new rules
Judge rules OMB can’t retroactively nix grants based on new rules
The court denied the Trump administration’s request to dismiss a lawsuit brought by 20 states.
dlvr.it
Neurobiologist @daboussi.bsky.social at @dgsomucla.bsky.social makes science accessible to everyone. Here she breaks down striking Nature paper showing COVID-19 mRNA vaccines nearly doubled 3-year survival in lung cancer patients receiving immunotherapy, doing far more than expected. t.co/GsfdxZaXUC
I love these PIP3 biosensors because it labels the plasma membrane so well. You can see the cell's edge so clearly along with any intracellular vesicles. Also, this cell is so blebby. This video was taken when I was still working on endocytosis :D Good old times! #FluorescenceFriday
We saw the craziest things when we imaged Saccharomyces acutely starved of glucose. All of the cells had these finger-like extensions that seemed to be coming from the PM. Markus Babst thinks they are extended eisosomes. pmc.ncbi.nlm.nih.gov/articles/PMC...
An intact human heart, rendered transparent. Because disease doesn't happen in 2D. Whole-organ tissue clearing and light-sheet microscopy reveal coronary vessels (magenta) and atherosclerotic plaques (gold) across the intact organ. More at: shorturl.at/iqTBh 🫀🔬 #FluorescenceFriday!
A friend of mine found these three kittens behind a Bay Area gas station. They are tame, vaccinated, and incredibly affectionate. Unfortunately, she's unable to keep them and I'm trying to find them a home. They are at risk of going to a shelter. Bay Area people, are you open to adopting?
Our review on glial orchestration of neurodevelopment is online at @cp-devcell.bsky.social! Great fun working with Krissy Sakers and Pat Sheehan from the Eroglu and Schafer labs, and special thanks to first author Krissy for her tremendous work bringing this to fruition! www.cell.com/developmenta...
Glia orchestrate neural circuit development
In this review, Sakers et al. discuss how astrocytes, microglia, and oligodendrocyte lineage cells actively regulate neural circuit formation, refinement, and stabilization. They propose that coordina...
cell.com
Why do animals age in such similar ways, yet live for wildly different spans - from days to a century? Our new paper in @NatureAging fits a damage accumulation model across 9 species and finds the knob that best predicts lifespan doi.org/10.1038/s435...
A damage accumulation model identifies distinct aging regimes across species - Nature Aging
Raz and colleagues fit survival data across species to a stochastic model of damage accumulation and removal. They report that damage production rate best predicts lifespan and reveal two distinct agi...
doi.org
☕Mani, Tardif, Rossier et al. show that mechanical stress triggers caveolin-1 release from caveolae, enabling its diffusion in the plasma membrane and interaction with signaling effectors to regulate intracellular signaling. 👉https://rdcu.be/frvPe www.nature.com/articles/s41...
Diffusing caveolin-1 scaffolds regulate mechanosignalling - Nature Cell Biology
Mani, Tardif, Rossier et al. show that mechanical stress triggers caveolin-1 release from caveolae, enabling its diffusion in the plasma membrane and interaction with signalling effectors to regulate ...
nature.com
Our lab in a nutshell! :)
🤔 How do organs measure and control their size? 🐟 The Mateus Lab @ritamateus.bsky.social at PoL & @mpi-cbg.de use #zebrafish to understand how organs form the right size and shape, at the right time, during development or regeneration. Learn more in our new video 👉 youtu.be/L7XUfk0s51E