Deborah Bourc’his
@deborahbourchis.bsky.social
PI at Institut Curie, Paris. Germ cells, epigenetics, DNA and RNA methylation, transposable elements
Coupes drastiques du budget de la recherche + durcissement des règles d’attribution des financements ANR «Allez à l’ERC!» qu’ils disent, mais l’ERC saturée prend des mesures pour limiter les candidatures #deadend#recherchefrançaise Une petition semble vaine mais il faut commencer quelque part 👉
Un pétition du collège des sociétés savantes pour mettre en avant le rôle de la recherche dans la campagne politique à venir et rappeler le sous investissement chronique en France depuis 20 ans. N'hésitez pas à faire ciculer recherche-publique-2027.fr
International Genome Dynamics course in Institut Curie-Paris (April 8-15), experimental and computational methods in multiomics,with a #TE centered session. Free registration, until Jan 15th Don’t miss it! 👉https://training.institut-curie.org/courses/Genome-Dynamics-2026 @institutcurie.bsky.social
This went under the radar but answers a fundamental question in Epigenetics... From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How? Outstanding work from Mathieu Boulard and colleagues www.biorxiv.org/content/10.6...
The transcription of a single olfactory receptor per neuron is enforced by epigenetic silencing of their enhancers
The ability to discriminate thousands of odors in our environment requires each olfactory neuron to express a single olfactory receptor from hundreds of available genes. The biochemical mechanism enfo...
biorxiv.org
🍽️🧬 How do diet and gut microbes shape fertility across generations? 🪱🔬 Our Laboratory at #InstitutPasteur is recruiting a PhD student to study epigenetic inheritance of fertility using C. elegans. Fully funded via the International PPU program. Apply now! 🌍 #PhDposition #Epigenetics #Inheritance
🎓 Applications for Institut Pasteur's PhD programs open Sept 1-Oct 20, 2025 for October 2026 entry. Apply to up to 4 projects across 6 programs: PPU, PPU-IMAGINE @institutimagine.bsky.social, PPU-@ox.ac.uk, PPU-EID @upcite.bsky.social & more 🧬 Register now ✍️ www.pasteur.fr/en/education...
Exactly two weeks left to submit your abstract to the EMBO Mobile Genome Workshop. ☝️this year we will select from abstracts 2 “long” talks to highlight last minute breakthrough from early career scientists. Apply! July 29th
⏰ Abstract deadline for 'The mobile genome' is 29 July! 👉 https://s.embl.org/mge25-01-bl Join us 4–7 Nov 2025 at EMBL Heidelberg (or online) to explore the impact of TEs across biology. 🧬🔍 ⭐🧑🏼🔬 24 talks + 15 flash talks from posters – don't miss out! #EMBOMobileGenome
Do you have transposon-related research cooking, with some cool results you are exciting to share? Start thinking about registering to #EMBOMobileGenome workshop! Nov 4-7 2025 in Heidelberg. One of the historical TE meetings, with a diverse and welcoming community. www.embl.org/about/info/c... 1/3
The mobile genome: genetic and physiological impacts of transposable elements
embl.org
Another excellent edition of the Sy-Stem meeting in Vienna! The outstanding program and the pleasure to see some of our former PhD students of the BDD #InstitutCurie turned into young, rising stem cell scientists!! @dannimklee.bsky.social @dianapinheiro.bsky.social
📣 #EMBOMobileGenome is open for registrations! Assembling experts in genomics, epigenetics, structural biology, evolutionary biology, and developmental biology to discuss the broad impact of TEs on organismal biology. 🧬🔍 📜 Submit abstract by 29 July! 👉🏼 https://s.embl.org/mge25-01-bl
Dear all, registrations are open for the Mobile Genome @EMBO workshop. Many slots for posters, short talks but also long talks for last minute groundbreaking results! Let’s meet again on Nov 4-7, 2025 in Heidelberg. www.embl.org/about/info/c...
The mobile genome: genetic and physiological impacts of transposable elements
embl.org
Thanks for sharing the first of the two positions that we will propose in the next 6 months @biovitenskap.bsky.social Stay tuned!
We are #hiring a postdoc to study the epigenetic imprinting of cell fate during adipogenesis. Cool interdisciplinary project to analyze ChIP-seq, ATAC-seq, Hi-C, and CAGE. The postdoc will be co-supervised by @chymkowitchlab.bsky.social and me. Spread the word! www.jobbnorge.no/en/available...
Juliane Glaser @julianeg.bsky.social opens her lab at the MPI Freiburg! She was a bright, fearless, and sooooo positive PhD student. I have no doubt she will also be as a PI! Apply to join her exciting projects 👇
It’s official 🎉 I am excited to share that I will start my lab this spring at the Max Planck Institute for Immunobiology and Epigenetics @mpi-ie.bsky.social in beautiful Freiburg 🤩🗻☀️ I am looking forward to new collaborations and working with the fantastic community in Freiburg & its surroundings!
📣 Registration for the next Non-Coding Genome course at @institutcurie.bsky.social closes on February 15th! Don't miss this opportunity to explore the versatility of non-genic DNA elements and non-coding RNAs with internationally renowned experts. ▶️ training.institut-curie.org/courses/non-...
Our new paper showing how loss of the nuclear pore protein TPR leads to activation of an inflammatory gene expression programme in senescence is now published in eLife: bit.ly/4h1VcFi @wbickmor.bsky.social @uoe-igc.bsky.social @elife.bsky.social
The international Curie « Noncoding Genome » course has been revamped! 👉 Dark genome in cell plasticity and heterogeneity. A session on TEs #TEsky with M.E. Torres Padilla, D.Trono and @aktast.bsky.social. Master, PhD and postdoc fellows, a week in Paris during the Spring? Apply before Feb 15th 📌
Centrophilic retrotransposon integration via CENH3 chromatin in Arabidopsis from Tetsuji Kakutani & colleagues - beautiful insights into control of transposon insertion into the centromeres www.nature.com/articles/s41...
Centrophilic retrotransposon integration via CENH3 chromatin in Arabidopsis - Nature
An Arabidopsis long terminal repeat retrotransposon integrates de novo into regions occupied by centromere-specific histone variant, showing the impact of centromeric chromatin on transposable element...
nature.com
🎓 Join us for our Spring School in Quantitative Biology: "Cell Dynamics in Developmental Systems" ✨ Featuring renowned speakers and hands-on workshops! Learn more and register: www.edu.bio.ens.psl.eu/spip.php?art...
The 2nd edition of the Paris-Munich Epigenetics meeting will be held April 9-11, 2025 in Paris. Attendance is free of charge. Please visit the website www.sfb1064.med.uni-muenchen.de/paris_munich... to find out more about the program and to register. #epigenetics
Join us at FMI as a Junior Group Leader! A unique opportunity to set up your lab in a vibrant international research institute with world-class research groups and facilities, generous core funding, a collegial and inclusive culture - and great colleagues 🤓!
📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...
Congratulations to our dear friend and ex-department director @institutcurie.bsky.social Edith Heard for the @cnrs.bsky.social 2024 Gold Medal. Science with no frontier and the sky as the only limit... @maitrejl.bsky.social @bardinlab.bsky.social @leopoldlab.bsky.social @ybellaichelab.bsky.social
I’m excited to share our latest study led by @giuliapasquesi.bsky.social out today in @cellpress.bsky.social , uncovering a new way transposons have been repurposed for human interferon signaling! Read on for a thread on cryptic splice variants, decoy receptors, and viruses (1/N) 👇🧵 #TESky 🧪
Regulation of human interferon signaling by transposon exonization
Transposable element exonization can yield functional protein isoforms as seen for primate-specific IFNAR2.
cell.com
Please RS/RT. #GordonConference on "Histone and DNA Modifications" #epigenetics #chromatin 20-25. July 2025. Il Ciocco, Italy. Great speaker lineup. ➡️Register now www.grc.org/histone-and-...
Delighted to announce a new call for applications for our Pathway to Independence programme. Now entering its third year, this scheme supports postdocs going on the job market in 2025 - with training, mentorship, profile-raising and networking opportunities. Application deadline 31 Jan 2025. 1/3
PI programme | Development | The Company of Biologists
PI programme | Development | The Company of Biologists Development's Pathway to Independence programme Development is excited to announce our call for our Pathway to Independence program...
journals.biologists.com
A reason I am very wary of the loose ways we think about 'epigenetics' is because of these kinds of conclusions: DNA methylation mediates the link between adversity and depressive symptoms. www.nature.com/articles/s44...
DNA methylation mediates the link between adversity and depressive symptoms - Nature Mental Health
Using epigenome-wide mediation analyses to investigate DNA methylation as a path between adversity and depression, the authors found 31 cytosine–guanine dinucleotides (CpGs) associated with risk and 3...
nature.com
The international Curie « Noncoding Genome » course has been revamped! 👉 Dark genome in cell plasticity and heterogeneity. A session on TEs #TEsky with M.E. Torres Padilla, D.Trono and @aktast.bsky.social. Master, PhD and postdoc fellows, a week in Paris during the Spring? Apply before Feb 15th 📌
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how: docs.bsky.app/docs/advance... #AcademicSky #HigherEd #Altmetrics
Action Intent Links | Bluesky
Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...
docs.bsky.app
Another great set of @gensocuk.bsky.social talks: 1) AFD neuron disruption in C. elegans results in an increase in Tc1 elements; 2) conserved LTRs generate extracellular sRNA; 3) effects of methyl-6-adenosine can be good or bad, depending on external factors; 1/2 🧵
Thrilled to announce that the EMBO workshop «Mobile Genome» will be back in Heidelberg, Nov 4-7th 2025 @EMBLEvents @EMBO. Registration open soon but you can already register interest. Organized with fantastic colleagues @juliusbrennecke @GonzalezLab_BCN @JoePetersLab www.embl.org/about/info/c...
The mobile genome: genetic and physiological impacts of transposable elements
embl.org
We are recruiting computational and wet-lab scientists and support international candidates. Please reach out if you are interested in working with us: Dark antigens, interferon responses, transposable elements, the HUSH complex, immuno-epigenetics and MORE....❤️