(Paraphrased) Please elevate the people, like the people quoted here, who are speaking up and speaking out despite risks to their own funding. It takes courage but it’s the right thing to do.
Ariel Levine
@ariellevine.bsky.social
Spinal cord and motor control scientist Levine-lab.org
Our latest: We develop a dynamical landscape modelling framework based on time resolved single-cell data Applied to neural tube fate decisions it shows cell fate decisions as flip bifurcations, a circular topology & it predicts unseen signalling regimes @plosbiology.org doi.org/10.1371/jour...
Dynamic Landscape Analysis of cell fate decisions provides predictive models of neural development from single-cell data
Applying dynamical systems theory to single-cell data can provide a detailed picture of the cellular states observed during cell fate decisions. This study presents a dynamic landscape analysis (DLA) ...
doi.org
How the cerebellum separates related contexts—now out in Nature! Martha Garcia-Garcia led this tour de force, with theory from @somnirons.bsky.social & Michał Wójcik. Martha is on the faculty market, and I could not recommend her more highly. My lab is also recruiting! www.nature.com/articles/s41...
Bsky hivemind: what are we liking for Xenium cell type classifiers these days? Have tried RCTD, tangram, and label transfer. 50% of the dataset is easy to classify, but wildly different results across classifiers for the other 50%. +1 if anyone’s specifically fought with spinal cord data. Thx!
Job descriptions for 2 new postdocs positions to study the spinal cord basis of motor control (Just looking at the letterhead for the new lab location has me so excited. Krembil Brain Institute, University Health Network, U. Of Toronto 🇨🇦, here we come!) @kbi-uhn.bsky.social @uhnresearch.ca
Ariel Levine@ariellevine.bsky.social · 2w agoWe have 2 postdoc positions available to study spinal mechanisms of motor control. Postdoc 1 will focus on how specific spinal cell types shape neural activity www.levine-lab.org jobs.smartrecruiters.com/UniversityHe...
We looking for a postdoc with NHP electrophysiology experience to do simultaneous Neuropixel recordings across the corticothalamic motor circuit to better understand the neural control of reaching and grasping. We start looking at applications on August 31st. docs.google.com/document/d/1...
Pruszynski Postdoc 2026
Postdoctoral Researcher, Control Policies in the Primate Motor Circuit Pruszynski Lab @ Sensorimotor Superlab The Pruszynski Laboratory at Western University is seeking a postdoctoral researcher to j...
docs.google.com
We have 2 postdoc positions available to study spinal mechanisms of motor control. Postdoc 1 will focus on how specific spinal cell types shape neural activity www.levine-lab.org jobs.smartrecruiters.com/UniversityHe...
Postdoctoral Researcher, Spinal Mechanisms of Motor Control - Neural Activity
Company Description: The University Health Network, where “above all else the needs of patients come first”, encompasses Toronto General Hospital, Toronto Western Hospital, Princess Margaret Canc...
jobs.smartrecruiters.com
One of my favorite rhetorical and analytical moves is joining things (showing that different, seemingly unrelated ideas are part of the same phenomenon) and taking them apart (resolving paradoxes by demonstrating that what appears like a contradictory thing is different things, lumped together). 1/
A diverse system has reservoirs of species and variation that may not be optimized for how things stand *now*, but that can move into niches created when things *change* in ways that lay waste to the previously dominant organisms. 65/
I love this dog. Lots going on with our move to 🇨🇦 but sitting on a beautiful balcony with this pup is a still and lovely start to the day
Exciting day! Step 1 of my move to 🇨🇦 is complete 🥳. And I have a whole new level of respect and admiration for science immigrants everywhere
Hi All! Rebekah Evans @cellularscale.bsky.social, Kim Dougherty, and I are delighted to invite you to the 19th Annual Pre-SfN Motor Symposium, to be held Friday, November 13 at Georgetown University! 1/n
Hi All! Rebekah Evans @cellularscale.bsky.social, Kim Dougherty, and I are delighted to invite you to the 19th Annual Pre-SfN Motor Symposium, to be held Friday, November 13 at Georgetown University! 1/n
If I were doing a postdoc now, I would *highly* consider this. The project, mentor, and environment are all fantastic!
Andrew Pruszynski@andpru.bsky.social · last mo.We're hiring! Postdoc position to study the neural control of reaching using high-density multi-area electrophysiology. 5 years of funding, great collaborative environment. Please share with anyone who may be interested. For details, see: docs.google.com/document/d/1...
Congratulations, @jeffreyafarrell.bsky.social, on winning the @socdevbio.bsky.social #2026SDB Elizabeth D. Hay New Investigator Award! Learn more about Jeff's science and career in his @dev-journal.bsky.social interview with @saanjbati.bsky.social.
Transitions in development – an interview with Jeffrey Farrell
Jeffrey Farrell is an Earl Stadtman Investigator at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), USA, where he heads the Unit on Cell Specification and ...
doi.org
Official job posting coming when I get back from the cottage but if you're interested in a post-doc doing multi-area high-density electrophysiology in the cortico-thalamic circuit during reaching, feel free to reach out!
Andrew Pruszynski@andpru.bsky.social · last mo.Very happy to receive a CIHR Project Grant to continue our work on how sensory signals are organized in the thalamo-cortical motor circuit.
Our paper made the cover of J Neuroscience! Great collaborative effort with @ottawahospital.on.ca, @elilillyandcompany.bsky.social, & @ariellevine.bsky.social, led by @carleton.ca grad students Katie Griffiths and Jennifer Armstrong. Proud PI moment. 😊 www.jneurosci.org/content/46/2...
Expression and Localization of NMDA Receptor GluN2 Subunits in Dorsal Horn Pain Circuits across Sex, Species, and Late Postnatal Development
Despite being essential mediators of pain processing, the molecular identity of N -methyl-d-aspartate receptor (NMDAR) subtypes in nociceptive dorsal horn circuits is poorly understood, especially bet...
jneurosci.org
Thrilled to share the latest pre-print from the lab – TLDR: we identified the (near) full ascending spinal projection neuron repertoire that gives rise to central itch/touch/pain/temperature sensation as well as sex specific neuron types in the mouse spinal cord. Thread below (1/n):
Deep Cellular and Spatial Profiling of the Mouse Spinal Cord Reveals Sex-Specific Neuron Types and the Ascending Projection Neuron Repertoire
The spinal cord gives rise to central somatosensation and orchestrates autonomic and motor control. How its cellular diversity achieves functions across sex, longitudinal axis and links the spinal cor...
biorxiv.org
The Battle over the Constitution Has Spread to American Science. I'm out in the @theatlantic.com today about the new OMB proposed rule. It's just the longtime agenda of the the Supreme Court. US science and cancer cures now all depend on us picking up a fight with the Roberts Court.
The Unitary Executive Takes Over New Territory
The Trump administration’s theory of how the federal government should work is a threat to American science.
theatlantic.com
The Neural Control & Computation Lab is recruiting a Postdoctoral Fellow to investigate the neural basis of learning, flexible neural computation, and skilled movement control using large-scale electrophysiology from single-neuron populations in non-human primates 🧠🐒 www.ncclab.ca/join-the-lab
Join the Lab — neural control & computation lab
ncclab.ca
Come work with us! We're looking for a new lab manager to help us develop new motion capture methods, new biosensors, and to hopefully learn something cool about the brain. Bonus: you get to do all this in the ATL and, in my humble opinion, we're nice people to work with! markolab.org/careers/
Natural behavior unfolds as a continuous stream of actions. Because these actions often occur in rapid succession, the brain must prepare multiple future actions while the current action is being executed. Our TICS piece explores how this works. www.sciencedirect.com/science/arti...
sciencedirect.com
Now published - the #BANC! A full central nervous system (CNS) connectome of a limbed animal at single-synapse resolution, enabling us to follow sensory-motor arcs and understand how the CNS controls the body. rdcu.be/fncjS. #neuroscience. Video by @quorumetrix.bsky.social 1/18
As someone interested in both genetics & neural activity, I appreciate the common challenge of linking causal function to system-level understanding. This excellent review by @jamesbriscoe.bsky.social & Maizels shows a way forward for gene networks in development pubmed.ncbi.nlm.nih.gov/41803457/
Gene regulatory networks: from correlative models to causal explanations - PubMed
Gene regulatory networks (GRNs) explain how the genome controls cellular behaviour and tissue morphogenesis, serving to connect molecular mechanism to functional output. Single-cell technologies now p...
pubmed.ncbi.nlm.nih.gov
🕔 This is the answer to "how do you have time" for advocacy. When I read NIH workforce data at 6 AM, I read as someone who can trace an OMB memo to the biological questions that won't get asked. The same mind that builds science can fight for it.
Unfortunately this is true, BNI is shutting down very suddenly and soon. We’re still sorting through the fallout, but many incredibly talented postdocs and technicians are taking a huge hit to their careers because of this. If you know of openings, even short term, I’d be happy to circulate them.
Ariel Levine@ariellevine.bsky.social · 4mo agoPosting for Vibhu Sahni: Due to unforeseen circumstances the Burke Neurological Institute will have to terminate its research operations 5/22. There are international postdocs on visas who are looking for new homes. Please reach out to Vibhu if you can help
How did motherhood change me? Motherhood did not make me soft. It made me hard and strong and scared of very very few things.
Hey All: our colleagues need our help. Please repost, share, and contact Vibhu if you can help!
Ariel Levine@ariellevine.bsky.social · 4mo agoPosting for Vibhu Sahni: Due to unforeseen circumstances the Burke Neurological Institute will have to terminate its research operations 5/22. There are international postdocs on visas who are looking for new homes. Please reach out to Vibhu if you can help
Posting for Vibhu Sahni: Due to unforeseen circumstances the Burke Neurological Institute will have to terminate its research operations 5/22. There are international postdocs on visas who are looking for new homes. Please reach out to Vibhu if you can help