Generative artificial intelligence creates delicious, sustainable, and nutritious burgers www.nature.com/articles/s41... #food #AI #LLMs #Burger #Nutrition
Joshua Frenster
@joshifrenster.bsky.social
Cell competition in development/gastruloids (postdoc Alfonso Martinez Arias) Previously: adhesion GPCRs in Glioblastoma (PhD Placantonakis Lab NYU) frensterlab.com
@johanduchene.bsky.social @sholtodavid.bsky.social Spent the last hour looking, found ten more apparently manipulated Western blots in Thermo Fisher's antibody verification data (across eight different catalogued products). Thread below. www.thermofisher.com/antibody/pro...
I received close to 200 applications for positions in my new lab and I absolutely underestimated the time it would take to work through everything while evaluating candidates 🫠... But it's also really fun to read so many promising profiles and personal stories!
🚨Last days to apply!🚨 The Frenster Lab is hiring to study how cell competition is regulated in early embryonic development. We use 3D Gastruloids from multiple species and have exciting crossovers of developmental and cancer biology! Join us at University of Freiburg #cellcompetition #gastruloid
Scientists led by Dr. @joshifrenster.bsky.social at @upf.edu have discovered that cell competition in gastruloids is stage-specific and driven by relative p53 levels during pluripotency exit. 📄 Read more: https://go.nature.com/41YmuXt 🎙️ Listen now: https://bit.ly/425e7JH
We are looking for outstanding scientists to develop ambitious research programs in molecular and cellular biology, with special interest in multidisciplinary projects and computational biology.More info: www.i2bc.paris-saclay.fr #MolecularBiology #CellBiology #ComputationalBiology #TeamLeaders#I2BC
Because #gastruloids allow measurements, they can teach us about quantitative traits. Exploring #CellCompetiion @joshifrenster.bsky.social et al www.nature.com/articles/s41... Biology as a matter of #Genes #Cells and #Numbers but of much that is #NotInTheGenes
Mosaic gastruloids reveal a temporal restriction for developmental cell competition - Nature Cell Biology
Frenster et al. utilize mosaic mouse gastruloids as a model of cell fitness and competition, identifying a temporal window between primed pluripotency and early gastrulation during which cell competit...
nature.com
🥳 I am happy to share our latest manuscript published in @natcellbio.nature.com We use #Gastruloids to study #CellCompetition during early mammalian development and find not only that this is highly pronounced in our system but also tightly restricted in time. (1/12) www.nature.com/articles/s41...
Mosaic gastruloids reveal a temporal restriction for developmental cell competition - Nature Cell Biology
Frenster et al. utilize mosaic mouse gastruloids as a model of cell fitness and competition, identifying a temporal window between primed pluripotency and early gastrulation during which cell competit...
nature.com
Very happy to announce that I will be joining the Faculty of Biology & @cibss.bsky.social at @uni-freiburg.de as an Emmy-Noether funded group leader. We will tackle the molecular and genetic basis of developmental timing and size control using diverse Oryzias species. We are hiring at all levels !
Evo-Devo-Tempo Lab
seleit-lab.com
The Frenster Lab is here! 🍾 I am so excited to start my #EmmyNoether funded group at @uni-freiburg.de this summer. Our group studies #CellCompetition dynamics during embryonic development using #gastruloids from multiple species. Thanks to the @dfg.de for creating this opportunity! FrensterLab.com
Frenster Lab | Cell Competition Dynamics
We study Cell Competition during Embryonic Development using 3D Gastruloids at the University of Freiburg. We view cells as interactive societies in development and cancer. Research, stem cells, Gastr...
frensterlab.com
We are excited to announce the first Western VGZT of Season 7! 🎉 🗓️ Thursday, October 2nd ⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET Our speakers: 👉 Antonia Weberling (@a-weberling.bsky.social) 👉 Sanjay Narayanaswamy (@sanjay-n.bsky.social)
Join the VGZT Eastern KEYNOTE lecture ☀️☕ TOMORROW 🗓️ Wednesday July 09 ⏰ 13:30 IST / 17:00 JST / 8:00 UTC / 10:00 CET Featuring: 1) Maithreyi Narasimha 👉Positioning tissues during Drosophila morphogenesis Jose Silva @josesilvalab.bsky.social 👉From founder cells to organogenesis-stage embryo model
Save the date 📅! Our TriNational #devbio #stemcell Meeting 2025 will be held in Freiburg on Sept. 19th. As always, participation is free and talks will be selected from early career scientists. Joun us 😊 Info: devstemcell.org/home @biozentrum.unibas.ch @uni-freiburg.de @igbmc.bsky.social
Big news! "researchers will be eligible to apply for a Starting Grant immediately after successfully defending their PhD, and at any time within the following ten-year period." #ERC #ERCstarting erc.europa.eu/news-events/...
Changes to the 2026 and 2027 Work Programmes
With the launch of the competitions for grants under ERC Work Programme 2026 in July of this year, several changes to the submission of applications and the evaluation of proposals will apply. The mai...
erc.europa.eu
I'm excited to join @pritiagarwal.bsky.social and @tarafinegan.bsky.social as a co-organizer for the International Developmental Mechanics Seminar Series. The series will resume in September 2025, and call for speakers is now open! More info is on our new website: sites.google.com/view/devmech...
📢 Fresh off the press and featuring new exciting experiments! 🧪 We show how glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signaling - happy to finally share this 😊 doi.org/10.1016/j.st... B2B with @jesseveenvliet.bsky.social lab: doi.org/10.1016/j.st... 🤩
I'm really grateful for the large turnout of our Gastruloid meeting in Barcelona. Close to 100 researchers from 9 countries. With the gastruloid field expanding, I hope that the community stays this close and that the meeting becomes an annual tradition! #gastruloids #conference
The Barcelona #gastruloid meeting has been a blast. A witness to a field that is maturing and a statement of a promise that lurks in its horizon. Thank you @joshifrenster.bsky.social @dias-andre.bsky.social and Ulla Fiuza for the organization, @EMBO, @ERC and the community for support.
Thrilled to announce that I am looking for a Research Technician/Assistant to join my lab @imbavienna.bsky.social. Please consider applying if you’re enthusiastic about #devbio #stemcells #teamwork and excited to help shaping a new lab! Thankful for any retweet! 🫶 imba.onlyfy.jobs/job/l6u2m980
Research Technician
IMBA - Institute of Molecular Biotechnology is one of the leading biomedical research institutes in Europe focusing on cutting-edge functional genomics and stem cell technologies. IMBA is located at t...
imba.onlyfy.jobs
We are hiring! Join the Stapornwongkul Lab as a Research Technician and investigate the tissue scale organization of metabolic processes and their impact on developmental processes. Apply using the link below.
First day of our Gastruloid Meeting in Barcelona kicking off with amazing talks and discussion and a room filled with gastruloid enthusiasts! #gastruloids #conference
Excited to share our latest paper in DevCell! We show how EOMES and the SWI/SNF complex collaborate to drive chromatin remodeling, establishing mesoderm and endoderm differentiation potential. Read the full paper here: www.cell.com/developmenta...
EOMES establishes mesoderm and endoderm differentiation potential through SWI/SNF-mediated global enhancer remodeling
Schröder et al. describe the molecular functions of the Tbx factor Eomes, which, together with the SWI/SNF chromatin remodeling complex, establishes enhancer accessibility at mesoderm and endoderm (ME...
cell.com
Do you want to illuminate your studies on innate immune responses? Our new biosensor monitors mtDNA from apoptosis, viral infections, other sources of dsDNA and environmental cGAMP. We also show that micro nuclei are poor activators of the #STING response
SIRF: Sergio Acebron @acebronsp.bsky.social @cosheidelberg.bsky.social and colleagues develop a new #biosensor reporting on functional interactions between dsDNA sensor STING and #IRF3, allowing to capture STING activation upon various triggers www.embopress.org/doi/full/10....
Thinking about the Spanish word "anoche", I realized that we forgot the English word "yestereve". Bring back concise words!
1/3 Embryogenesis requires fit cells. Here, following work from @miguel-torres-1963.bsky.social & @tristanrodriguez72.bsky.social and led by @joshifrenster.bsky.social we develop a #gastruloid model of #CellCompetition www.biorxiv.org/content/10.1... showing it recapitulates much of the embryo 🧵
www.biorxiv.org/content/10.1... Here we explore the role of #Wnt and #Nodal signalling during mammalian gastrulation using #gastruloids. Building on the work of many labs, we propose that antagonistic signalling-dependent #modularity in the PS establishes the early mammalian body plan.
A temporal coordination between Nodal and Wnt signalling governs the emergence of the mammalian body plan
Nodal and Wnt signalling play an important role in the emergence of the mammalian body plan, primarily by orchestrating gastrulation and primitive streak formation. While the literature suggests that ...
biorxiv.org
We've wondered for a while why #gastruloids are so sensitive to initial cell numbers. Here www.biorxiv.org/content/10.1... led by U, Fiuza, we explore this & observe effects of a number of variables on final structure and think what this tells us @ embryogenesis #IInNumbersWeTrust #NotInTheGenes
For the dev bio crowd : there is a call for junior group leader at Institut Pasteur in Paris and one of the axis covered is related to development. Come and join us in this exciting place and become one of our colleague @devstempasteur.bsky.social Please RT !! research.pasteur.fr/fr/call/call...
Call for applications 2025 – Creation of new research groups at the Institut Pasteur | Research - Institut Pasteur
research.pasteur.fr
When late science-nights reward you with those types of views, it makes it all worth it!
Next week, we’re back with two unique development talks: mouse gastruloids 🐭 with Kristina Stapornwongkul and turtles 🐢 with Agáta Horáčková & Barbora Straková. Mark your calendar—you won’t want to miss this! 🗓️ Dec 5, 12:30 EST / 18:30 CET / 17:30 UTC 🕥