Delighted to host Professor @annagloyn.bsky.social from @stanfordio.bsky.social receiving an Honorary Doctorate at the @medfacultyunibe.bsky.social and @unibergen.bsky.social. Her with her father♥️♥️
Anna Gloyn
@annagloyn.bsky.social
Professor of Pediatrics (Endocrinology) & Genetics @stanford Interested in diabetes /human genetics / islet biology / precision medicine Women in science 🧬🧫🔬
What a week! An amazing honor to be awarded an honorary doctorate from the Unviersity of Bergen. Thank you to my hosts @njolstad.bsky.social & Dean Marit Bakke for their amazing hospitality.
Our dean, Marit Bakke is introducing Professor Anna Gloyn's lecture @annagloyn.bsky.social Professor Anna Louise Gloyn will be appointed honorary doctor @unibergen.bsky.social on May 21, 2026.
What an honor to deliver this years #TransatlanticAllianceAward at the #ECE2026 meeting. Thank you to the @endocrinesociety.bsky.social & @esendocrinology.bsky.social for this recognition of the collaborative science bridging Europe and North America I have been part of for the last 30 years.
Our latest work on PAM is out #GenomeMedicine We show that PAM-T2D risk alleles result in "GLP-1 resistance". I am so proud of this collaborative work championed by two incredible early career academics - Mahesh Umpathysivam & Elisa Araldi (not on BlueSky) link.springer.com/article/10.1...
Type 2 diabetes risk alleles in peptidyl-glycine alpha-amidating monooxygenase influence GLP-1 levels and response to GLP-1 receptor agonists - Genome Medicine
Genome Medicine - Type 2 diabetes (T2D) is a leading cause of morbidity and mortality worldwide. Despite the availability of multiple glucose-lowering agents, only half of individuals with T2D...
link.springer.com
For ~century, we’ve asked: why do proliferating cells ferment glucose even when O2 is around? I’m thrilled to share our latest work @natmetabolism.nature.com, led by @thebiokimist.bsky.social. By leveraging conditional essentiality in HPLM, we propose a provocative new answer to this classic Q. 🧵
Tracking the details of an experiment in successively cited Methods sections
Congratulations Professor Gloyn! @Stanford @TheEndoSociety endocrinenews.endocrine.org/anna-gloyn-w... @annagloyn.bsky.social 🧪
Anna Gloyn Wins 2026 Transatlantic Alliance Award in Endocrinology - Endocrine News
The Endocrine Society and The European Society of Endocrinology (ESE) are delighted to announce Anna Gloyn, DPhil, FMedSci, as the winner of the fifth annual Transatlantic Alliance Award. The Transat...
endocrinenews.endocrine.org
Anna Gloyn (@annagloyn.bsky.social), Jie Liu, Noel Burtt, and Marcela Brissova from the PanKbase team gave a webinar for the HIRN webinar series. If you missed it and want to know how PanKbase might help compliment your type I diabetes research, watch it here: youtu.be/3qLiBdIOJhY?...
HIRN Webinar: PanKbase: A Centralized Knowledge Base of the Human Pancreas for Diabetes Research
YouTube video by Human Islet Research Network
youtu.be
It's a big day at the Academy as we welcome our 2025 Fellows 🎉 We’re celebrating 54 remarkable scientists joining our esteemed Fellowship of 1,450 leading researchers. 📣 Meet our new Fellows: ow.ly/VtGs50WmPqc 🌟 And our Honorary Fellows: ow.ly/4syL50WmPyi And stay tuned for highlights!
🎉 Our New Fellows Admissions Day is in full swing! We're welcoming an inspiring group of leaders advancing research and shaping the future of medicine! 💡
Really proud of this Exeter–Stanford collaboration identifying bi-allelic variants in PAX4 as a novel cause of transient neonatal diabetes—the first new genetic cause of this subtype described in over a decade. This work expands our understanding of beta cell development. 🔗 doi.org/10.1016/j.mo...
Complete Loss of PAX4 causes Transient Neonatal Diabetes in Humans
Gene discovery studies in individuals with diabetes diagnosed within 6 months of life (neonatal diabetes, NDM) can provide unique insights into the de…
sciencedirect.com
Our DEG explorer enables interactive visualizations of differential gene expression within human pancreatic islets. Data was generated from the integrated single-cell RNA sequencing from 140 human donors sourced from HPAP, IIDP, and Prodo. Check out the tutorial here: youtu.be/jL8SgEMF_sg?...
PanKbase Differential Gene Expression Browser - June 2025
YouTube video by PanKbase
youtu.be
Please check out our new paper on bioRxiv evaluating genetic background influences on heterogenous responses to S64F MAFA!: www.biorxiv.org/content/10.1...
Genetic background influences the heterogeneous phenotypes driven by the MAFAS64F MODY variant in male mice
Pancreatic β-cells require several key factors to appropriately secrete insulin to maintain euglycemia. One such factor is MafA, a transcription factor fundamental to β-cell function. We previously id...
biorxiv.org
Thrilled and honored to be a part of this amazing session on rare genetics and GWAS in diabetes with @Romina39356029 @annagloyn.bsky.social and @miriam_udler ! #ADA2025
Dr. Anna Gloyn at #ADA2025: Multiomic data reveals diabetes heterogeneity, linking polygenic scores, islet traits, and regulatory networks. @amdiabetesassn.bsky.social @annagloyn.bsky.social #ADASciSessions #T2D #genomics #multiomics
PanKbase #ADA spotlight: PanKbase PI, Dr. Jie Liu, Associate Professor of Computational Medicine and Bioinformatics Michigan Medical School will be presenting during the session "Decoding Diabetes—AI-Driven Advances in Genetic Research". June 23rd 3:15 PM - 4:15 PM. Look forward to seeing you there!
PanKbase #ADA poster alert!!! Dr. Ha Vu (@hahvu.bsky.social) will be presenting her work on our PanKbase platform: "PanKbase Integrated Single-Cell Map—A Comprehensive Atlas of Human Pancreatic Islets Unlocking Insights into Type 1 and Type 2 Diabetes" Sunday, June 22 at 12:30p CT (Poster 2121-LB).
Planning your #ADA2025 visit? Don’t miss the NIDDK #DataScience Corner hosted by #dkNET! 📍 Between ADA Member Lounge & Product Theater 1 🗓 Visit during the reception or exhibit hours 🎉 Celebrate 75 years of #NIDDK! 🔗 dknet.org/data-science... #ADASciSessions
Welcome to Chicago! If you're at the 85th Scientific Sessions of the #ADA, stop by the PanKbase booth 1047 in the exhibit hall to learn about the our updated single cell browser, ask questions, or give us feedback. youtu.be/sNEGvSIjh3M?...
PanKbase Single Cell Browser Tutorial - June 2025
YouTube video by PanKbase
youtu.be
Romina Bevacqua and PanKbase PI Anna Gloyn (@annagloyn.bsky.social) preview the presentations of #ADA session Genetic Regulation of Beta-Cell Mass and Function in Humans—Lessons from GWAS and Rare Genetics happening June 22, at 1:30 p.m. CT in Room W194 AB www.adameetingnews.org/genetic-regu...
Genetic Regulation of Beta-Cell Mass and Function in Humans—Lessons from GWAS and Rare Genetics - ADA Meeting News
Anna Gloyn, DPhil, and Romina J. Bevacqua, PhD, preview presentations at the 85th Scientific Sessions. Attendees in Chicago can watch the session in-person Sunday, June 22, at 1:30 p.m. CT.
adameetingnews.org
Check out the platform at pankbase.org. Come see us at the 85th Scientific Sessions of the American Diabetes Association #ADA2025 #DataScience Booth 1047!!! We'd love to discuss more what we're doing and hear your feedback.
PanKbase | PanKBase
pankbase.org
What is PanKbase? Watch our introduction video to find out: youtu.be/glGHni2tXGg?....
PanKbase Introduction Video
YouTube video by PanKbase
youtu.be
We're less than two weeks away from #ADA2025. PanKbase, booth 1047 will be located in the NIDDK #DataScience corner. Come see us to learn more about the platform and meet the PanKbase team.
PanKbase #ADA2025 spotlight: PI @annagloyn.bsky.social presents Sun. the 22nd at 2pm CDT. Session: Genetic Regulation of Beta-Cell Mass and Function in Humans: Lessons from GWAS and Rare Genetics. Her talk: "Integrating Multiomic Data to Understand Complex Gene Regulatory Networks in Islets"
Progress in Polygenic Risk Scores (PRS), which take multiple disease-modifying variants into account, are increasingly powerful tools to identify, predict and classify #diabetes mellitus @natrevendo.nature.com www.nature.com/articles/s41...
Diabetes mellitus polygenic risk scores: heterogeneity and clinical translation - Nature Reviews Endocrinology
In this Review, the authors discuss different methods for assessing polygenic risk of diabetes mellitus and the utility of polygenic risk scores in classifying and screening for diabetes mellitus. The...
nature.com
📣 Latest from the lab: Performance of deep-learning-based approaches to improve polygenic scores www.nature.com/articles/s41... Its thought deep learning will substantially improve PGS but the reality is MANY have tried but no/little gain has been seen so far. Here we report our negative results.
New content online: Diabetes mellitus polygenic risk scores: heterogeneity and clinical translation
Diabetes mellitus polygenic risk scores: heterogeneity and clinical translation
Nature Reviews Endocrinology, Published online: 04 June 2025; doi:10.1038/s41574-025-01132-wIn this Review, the authors discuss different methods for assessing polygenic risk of diabetes mellitus and the utility of polygenic risk scores in classifying and screening for diabetes mellitus. The current limitations of these scores and ways of overcoming these limitations are also covered.
nature.com