Katrin Kierdorf
@katrinkierdorf.bsky.social
Phagocyte lover 👾//interested in macrophage development // University Of Freiburg
Join us for the next 📢 #CIBSS Seminar! 🗓️ 20 Oct 2026 | 12:00–13:00 👉 Dr. rer. nat. Julia Kolter (Institute for Infection Prevention and Control (IIK), Medical Center University of Freiburg) 📍 Lecture Hall, Institute of Biology I, Hauptstr. 1, Freiburg www.cibss.uni-freiburg.de/news-and-eve...
A Review by @katrinkierdorf.bsky.social, Markus Sperandio, Mathias Hornef & @philipp359.bsky.social discusses how perinatal immunity is tailored to mediate the transition to postnatal life through a high degree of temporal plasticity.
Plasticity of the infant immune system during the perinatal period - Nature Reviews Immunology
Immune plasticity during the perinatal period enables mammalian offspring to successfully navigate the transition from prenatal, intrauterine life to postnatal, extrauterine life. This Review highligh...
nature.com
What a great start to the annual DGfI meeting!! The ELINE-PILOT Joint Satellite Symposium on Early Life Immunity was fantastic 🧑🔬🧫🧬! Thank you for crowding the lecture hall, amazing to see so many people interested in this topic 🫶🏻! Great talks, great discussions, great people!
📢 New webinar coming soon 📢 Prof. Katrin Kierdorf from University of Freiburg be our next speaker on September 1st. Check all the information in the flyer and add it to your calendar!
🥁🥁 our newest work is out🎉🎉 www.science.org/doi/full/10.... What a wonderful collaboration with the Sagar lab and I am really looking forward to our next joint study 😎 Shout out to the incredible students: David, Alex and Lara! You guys did such a wonderful job with this work 🥰
Distinct postnatal trajectories of mouse dendritic epidermal T cells and Langerhans cells independent of microbiota
The mouse epidermis harbors two key resident immune populations—dendritic epidermal T cells (DETCs), a subset of invariant γδ T cells, and Langerhans cells (LCs), specialized tissue-resident macrophag...
science.org
Our PhD program IMPRS-EBM of #Epigenetics, #Biophysics & #Metabolism will open for applications next week. 📢 Want to work at the forefront of epigenetic research at an MPI? Looking for a fully-funded #PhDposition at Max Planck? Here is your chance: www.ie-freiburg.mpg.de/IMPRS-PhD-Pr...
Fetal liver #macrophages support red blood cell production and pyrenocyte clearance in the developing embryo. Stifter, Greter et al. demonstrate that XPR1, a phosphate exporter and regulator, is required for the development and function of fetal liver macrophages. rupress.org/jem/article/...
Nature research paper: Architecture of the neutrophil compartment go.nature.com/3KzY1CV
Architecture of the neutrophil compartment - Nature
Mapping of the neutrophil compartment using single-cell transcriptional data from multiple physiological and patological states reveals its organizational architecture and how cell state dynamics and trajectories vary during health, inflammation and cancer.
go.nature.com
Please share: we have an open postdoc position!🪰🪰👾We are looking for a motivated Drosophilist to join our team and explore the role of hemocytes in interorgan signaling! Interested?😎send us your application or contact me! Looking forward to hear from you! www.uniklinik-freiburg.de/karriere/ste...
Postdoctoral Researcher (m/f/d) | Universitätsklinikum Freiburg
uniklinik-freiburg.de
Love goes out to all the fly peeps @edrc2025.bsky.social, fantastic meeting and we had brilliant time together with @classenlab.bsky.social in Alicante!♥️♥️♥️ Can’t wait for the EDRC 2027 in Bonn!
New leadership for #CIBSS! Welcome Sonja-Verena Albers as new spokesperson & congrats to Claudine Kraft on her confirmation. Together with Jürgen Kleine-Vehn, they’ll lead CIBSS into its #NextChapter – following Wolfgang Driever & Carola Hunte. More info: kurzlinks.de/fkv4
The future of @cibss.bsky.social @uni-freiburg.de is about teamwork, curiosity, and collaboration across disciplines. We are thrilled to be in this together @kraftlabfr.bsky.social @archaellum.bsky.social @kleinevehnlab.bsky.social !
CIBSS – Centre for Integrative Biological Signalling Studies@cibss.bsky.social · last yr.New leadership for #CIBSS! Welcome Sonja-Verena Albers as new spokesperson & congrats to Claudine Kraft on her confirmation. Together with Jürgen Kleine-Vehn, they’ll lead CIBSS into its #NextChapter – following Wolfgang Driever & Carola Hunte. More info: kurzlinks.de/fkv4
To all hemocyte lovers: Angela and me are hosting a special issue on Drosophila hemocytes 🪰👾We have some brillant drosophilists around the world who agreed to submit a review to this special issue! If you are also interested to contribute, reach out to us and we can give you more information!
Developmental Biology@devbiol.bsky.social · last yr.CALL FOR PAPERS! 🪰 Drosophila blood cells - Our #DBspecialissue highlights novel findings on hemocyte diversity in Drosophila melanogaster. The reviews explore diversity in terms of ontogeny, functional specification and organ-organ communication. Submit today! tinyurl.com/357v25tj
Our newest study is out🥳! Big shout out to Alex and Philippe for their amazing work here 🫶🏻 and thx to all collaborators who helped us during this journey! And let me tell you… this is just one tiny puzzle piece of understanding microglia/macrophage tissue homing 😎 www.cell.com/developmenta...
Early microglia progenitors colonize the embryonic CNS via integrin-mediated migration from the pial surface
Petry et al. demonstrate a defined migration route of microglia progenitors from the surrounding mesenchyme into the embryonic CNS. This process relies on integrin activation and interactions with the...
cell.com
Join our "Advances in Single-Cell Technologies" meeting in December in Freiburg, co-organised with Marco Prinz and @katrinkierdorf.bsky.social. Excellent line-up of speakers covering spatial technologies, lineage tracing, computational methods, and more. www.uniklinik-freiburg.de/single-cell-...
Thank you to Lai Guan Ng and Lihui Dong for highlighting our work! www.cell.com/cancer-cell/...
Tumor neutrophils rewired from birth
Systemic responses during tumor progression reshape granulopoiesis. In this issue of Cancer Cell, Garner et al. show that tumor-derived signals reprogram neutrophil development early in myelopoiesis. ...
cell.com
Latest #ResearchNews from #NeuroImmunology: Katrin Kierdorf, Marco Prinz and colleagues show how the brain's own immune cells react in Alzheimer's disease and identify an important #Signalling pathway. Recently published in @natneuro.nature.com. Read more 👉 www.nature.com/articles/s41...
Response of spatially defined microglia states with distinct chromatin accessibility in a mouse model of Alzheimer’s disease - Nature Neuroscience
The dynamics of microglia states adjacent to or far from amyloid-beta plaques are unclear. Here the authors show that non-plaque-associated microglia modulate the cell population expansion in response...
nature.com
Universität Freiburg@uni-freiburg.de · last yr.#Alzheimer betrifft nicht nur das Gedächtnis, sondern auch das Immunsystem des Gehirns: Freiburger Forschende identifizieren im Tiermodell wichtigen Signalweg und zeigen, wie hirneigene #Immunzellen bei Alzheimer reagieren. ➡️ ufr.link/prinz-alzheimer @cibss.bsky.social @uniklinik-fr.bsky.social
#Alzheimer betrifft nicht nur das Gedächtnis, sondern auch das Immunsystem des Gehirns: Freiburger Forschende identifizieren im Tiermodell wichtigen Signalweg und zeigen, wie hirneigene #Immunzellen bei Alzheimer reagieren. ➡️ ufr.link/prinz-alzheimer @cibss.bsky.social @uniklinik-fr.bsky.social
The first comprehensive map of HSC metabolism. 😱 The team of @ninacabezas.bsky.social published the first integrated map detailing metabolic & molecular changes in human blood stem cells as they age, specialize, or turn cancerous with many astonishing insights More in @natcellbio.nature.com or ⬇️
Mapping the metabolism of blood stem cells
Researchers at the Max Planck Institute of Immunobiology and Epigenetics and ETH Zurich have created the first comprehensive metabolic profile of human blood stem cells. This opens up new possibilitie...
ie-freiburg.mpg.de
🥳🥳🥳Countless years in the making and there it is 🫶🏻 Exceptionally proud of my lab and especially Lance who was driving this project for the last years! 🏎️Thank you to all the fantastic collaborators ♥️ I hope everyone enjoys reading our little story! www.nature.com/articles/s41...
Response of spatially defined microglia states with distinct chromatin accessibility in a mouse model of Alzheimer’s disease - Nature Neuroscience
The dynamics of microglia states adjacent to or far from amyloid-beta plaques are unclear. Here the authors show that non-plaque-associated microglia modulate the cell population expansion in response...
nature.com
Brilliant talk by Lance from our lab at the 2nd ASPIRE Meeting about his soon to be online study on understanding microglia subsets in AD and what we can learn about windows of opportunity to modulate them!
Few dates left to apply for this tenure-track professorship on Single-Cell Systems Biology in my department at @uni-wuerzburg.de. Competitive package and highly attractive research environment at the Institute of Systems Immunology.
Dominic Grün@dominicgrun.bsky.social · last yr.We have an attractive opening for a tenure-track professorship in Single-Cell Systems Biology. Excellent package and infrastructure at @uni-wuerzburg.de Institute of Systems Immunology. Great place to live and work in the heart of the franconian wine region! jobs.sciencecareers.org/job/673667/j...
So excited to be part of the 11th cardiac regeneration and vascular biology meeting in San Servolo! Excellent science and such a beautiful location
Please share our latest work @natcomms.nature.com „ONE MICROBIOTA TO RULE THEM ALL“ doi.org/10.1038/s414... A big THANK YOU to the entire team of great scientists! #wildlings doi.org/10.1126/scie... www.science.org/doi/10.1126/... www.cell.com/trends/immun... @fau.de @Hornegger.bsky.social
Please share! Hiring PIs working in microbiome, metabolism, cancer, allergies, autoimmunity, neurological and infectious diseases. We offer SPF-, gnotobiotic- and wildling-models + generous lab space + top notch equip., e.g. SONY ID7000, 10X Xenium, MACSima. Contact: stephan.rosshart@uk-erlangen.de
Save the date 📅! Our TriNational #devbio #stemcell Meeting 2025 will be held in Freiburg on Sept. 19th. As always, participation is free and talks will be selected from early career scientists. Joun us 😊 Info: devstemcell.org/home @biozentrum.unibas.ch @uni-freiburg.de @igbmc.bsky.social
The #Rosshart Lab goes wild again! Ever wondered whether using #Wildlings in our research would change the outcome of our results? 🤔💡 #immunosky @fau.de www.nature.com/articles/s41...
Laboratory mice engrafted with natural gut microbiota possess a wildling-like phenotype - Nature Communications
Here, the authors apply a standardized system, called TXsystem, to transplant wild mouse gut microbiota into SPF mice, developing “TXwildlings” mice that stably retain natural microbiota and human-lik...
nature.com
We are thrilled to have just found out: CIBSS has secured continued funding under the #ExcellenceStrategy! This major boost will enable us to accelerate our research into biological signalling and lay the groundwork for next-generation insights from 2026 to 2032!
Warm-up for the big international symposium for early life immunity tomorrow with our CoPILOT crew! #TRR359 #IRTG-CoPILOT