Devin Schweppe

@dschweppe.bsky.social

Associate Professor at UW Genome Sciences developing/applying proteomic technologies | he/him/his | Views are my own.

With a few days since it's been out @keribackus.bsky.social @oligopain.bsky.social and I wanted to highlight a few of our favorite aspects of POCA for photocatalytic proximity labeling of DNA, RNA or proteins. (1) POCA builds on standard in situ hybridization and immunofluorescence workflows.

Bild
Keri Backus@keribackus.bsky.social · 3mo ago

Super excited to launch POCAxOMAP with @dschweppe.bsky.social and @oligopain.bsky.social and led by Eli Biletch, Conor Herlihy and Lidan Li. If you’ve ever wanted to do proximity labeling on DNA, RNA, or protein without genetic engineering, look no further. www.biorxiv.org/content/10.6...

Really excited to have lead this work alongside Eli and Lidan! I’d love to chat about applying our platform to your system of interest, the advantages of parallel imaging and proteomics, ability to target DNA, RNA, and protein, or advantages over enzyme-based labeling with anyone who’s interested!

Keri Backus@keribackus.bsky.social · 3mo ago

Super excited to launch POCAxOMAP with @dschweppe.bsky.social and @oligopain.bsky.social and led by Eli Biletch, Conor Herlihy and Lidan Li. If you’ve ever wanted to do proximity labeling on DNA, RNA, or protein without genetic engineering, look no further. www.biorxiv.org/content/10.6...

Excited to see this collaborative work with @oligopain.bsky.social and @keribackus.bsky.social out as a preprint now! Took a ton of work from a great team of scientists @uwgenome.bsky.social and #UCLA The imaging coupled with proteomics open our eyes to new aspects of subcellular organization!

Keri Backus@keribackus.bsky.social · 3mo ago

Super excited to launch POCAxOMAP with @dschweppe.bsky.social and @oligopain.bsky.social and led by Eli Biletch, Conor Herlihy and Lidan Li. If you’ve ever wanted to do proximity labeling on DNA, RNA, or protein without genetic engineering, look no further. www.biorxiv.org/content/10.6...

Excited to see this collaborative work with @oligopain.bsky.social and @keribackus.bsky.social out as a preprint now! Took a ton of work from a great team of scientists @uwgenome.bsky.social and #UCLA The imaging coupled with proteomics open our eyes to new aspects of subcellular organization!

Keri Backus@keribackus.bsky.social · 3mo ago

Super excited to launch POCAxOMAP with @dschweppe.bsky.social and @oligopain.bsky.social and led by Eli Biletch, Conor Herlihy and Lidan Li. If you’ve ever wanted to do proximity labeling on DNA, RNA, or protein without genetic engineering, look no further. www.biorxiv.org/content/10.6...