📣 Abstract submission and early registration are now OPEN for the 7th European Cilia Conference—an official EMBO workshop! 📅 8–12 March 2027 📍 Stresa, Italy Submit and register: meetings.embo.org/event/27-cilia www.eurocilia.eu #EMBOCilia #Cilia2027
Tubulin (green) & #BILBO1 (magenta) in #Trypanosoma brucei. 3D MINFLUX shows BILBO1's nanoscale architecture at the flagellar pocket collar. More: Zelená et al., PLOS Biology (link in reply). Image: Mélanie Bonhivers (@mbonhivers.bsky.social), CNRS/Univ. Bordeaux #fluorescencefriday #MINFLUX
The CNRS has opened a Junior Professor Chair (CPJ) call in Parasitology, and the Microbiologie Fondamentale et Pathogénicité (MFP, Bordeaux) laboratory is among the potential host institutions. More information: www.insb.cnrs.fr/fr/cnrsinfo/... #Parasitology #Protozoology #ResearchJobs #CNRS
Junior Professor Chairs (CPJ) 2026 – CNRS Biology
CNRS Biology is recruiting researchers through its Junior Professor Chair (CPJ) program, subject to final approval by the French Ministry of Higher Ed
insb.cnrs.fr
Hello #world, meet 1,000× Expansion Microscopy. A small gel would grow to the size of an Olympic swimming pool, while amino-acid-scale distances become visible with ordinary light microscopy. Led by Helena Hu from @eboyden3.bsky.social's lab, in collab with us. Story: www.biorxiv.org/content/10.6...
Combined KIN2A and KIN2B knockdown showed that they were involved in IFT and flagellar length control, @ebertiaux.bsky.social picked up by developing the grow-and-lock model doi.org/10.1016/j.cu... Related findings were made by the group of @mattwelchlab.bsky.social https://doi:10.1242/jcs.129213
Flagella can be assembled by IFT without the canonical heterotrimeric kinesin! Grab a cup of tea or coffee and follow a story that started 25 years ago
bioRxiv Cell Biology@biorxiv-cellbio.bsky.social · 3mo agoLife without heterotrimeric kinesins: trypanosomatids use a combination of homodimeric kinesin-2 motors to drive intraflagellar transport https://www.biorxiv.org/content/10.64898/2026.05.12.724483v1
Life without heterotrimeric kinesins: trypanosomatids use a combination of homodimeric kinesin-2 motors to drive intraflagellar transport https://www.biorxiv.org/content/10.64898/2026.05.12.724483v1
We are very pleased to announce Prof. Paul Guichard and Dr. Virginie Hamel @centriolelab.bsky.social as joint winners of the RMS Award for Light Microscopy 🔬 👏 🏅 Huge congratulations to both! Read more about Paul and Virginie's achievements: www.rms.org.uk/resource/pro...
Hello everyone, we had a great meeting yesterday @institutimagine.bsky.social , thanks again to all the speakers for their very interesting talks on primary and motile #cilia #flagella #ciliopathies! Next one is organized by Caroline Brun, Marine Laporte, Véronique Morel in Aussois in September!
A super detailed protocol + video on Cryo-ExM - Cryo-Expansion Microscopy, led by the labs of our former postdocs @marinelap.bsky.social & @ebertiaux.bsky.social. Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...
As a Christmas present, our Jove paper with @ebertiaux.bsky.social is out and available for everyone ! Check this out & thanks @centriolelab.bsky.social for the nice highlight
Paul & Virginie - Centriole Lab@centriolelab.bsky.social · 7mo agoA super detailed protocol + video on Cryo-ExM - Cryo-Expansion Microscopy, led by the labs of our former postdocs @marinelap.bsky.social & @ebertiaux.bsky.social. Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...
How does C2CD3 contribute to distal appendage formation in centrioles? @ebertiaux.bsky.social @centriolelab.bsky.social show that C2CD3 architecturally organizes the distal #centriole, bridging the luminal distal ring complex & peripheral appendage sites @plosbiology.org 🧪 plos.io/496XZuH
Happy to share our fun team-up with @centriolelab.bsky.social & @stearnslab.bsky.social to reveal the architecture of the mammalian centriole’s Distal Ring 🛟. Very cool multiscale integration of #UExM 📏🔬with #CryoET ❄️🔬. Congrats to @ebertiaux.bsky.social & @computingcaitie.bsky.social #TeamTomo 🧪
PLOS Biology@plosbiology.org · 8mo agoHow does C2CD3 contribute to distal appendage formation in centrioles? @centriolelab.bsky.social show that C2CD3 acts as a central architectural organizer of the distal #centriole, bridging the luminal distal ring complex & peripheral appendage sites @plosbiology.org 🧪 plos.io/496XZuH
🥳 Our new paper on C2CD3 is out in @plosbiology.org With the labs of @cellarchlab.com , @chgenoud.bsky.social , and @stearnslab.bsky.social , we revealed the mammalian centriole Distal Ring architecture by combining #UExM and in situ #CryoET. Big congrats to @ebertiaux.bsky.social and all involved.
PLOS Biology@plosbiology.org · 8mo agoHow does C2CD3 contribute to distal appendage formation in centrioles? @centriolelab.bsky.social show that C2CD3 acts as a central architectural organizer of the distal #centriole, bridging the luminal distal ring complex & peripheral appendage sites @plosbiology.org 🧪 plos.io/496XZuH
Thrilled to share that my postdoc paper has just been a published in @plosbiology.org ! Thank you to all co-authors, and a special thanks to Paul and Virginie @centriolelab.bsky.social for their support throughout this work. Proud of what we achieved together! journals.plos.org/plosbiology/...
The luminal ring protein C2CD3 acts as a radial in-to-out organizer of the distal centriole and appendages
The centriolar protein C2CD3 has been suggested to be crucial for distal appendage formation in centrioles, but its precise mechanistic role remains unclear. Using a combination of ultrastructure expa...
journals.plos.org
Our latest T7SS study is now out in Science Advances! We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery. www.science.org/doi/10.1126/...
A ubiquitin-like protein controls assembly of a bacterial type VIIb secretion system
Cryo-EM structure reveals how a ubiquitin-like protein orchestrates assembly of a bacterial weapon system.
science.org
Honored to receive the FEBS Booster Funds 2025. My sincere thanks to FEBS for this recognition and their support of early-career researchers. This funding will greatly help advance my work. Congratulations as well to all fellow 2025 awardees.
We hire! The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities. More details here: cytomorpholab.com/index.php/jo...
The flagellar pocket collar (FPC) is a cytoskeletal structure essential for nutrient uptake & immune evasion in #Trypanosome. @mbonhivers.bsky.social &co use U-ExM to provide novel insights into FPC biogenesis, and reveal 2 unknown cytoskeletal structures @plosbiology.org 🧪 plos.io/4n3bWi6
Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1... Soon at @spirochrome.com Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social
🚨 New EMBO Practical Course! Ultrastructure Expansion Microscopy: From Cells to Tissue 🔬 📅 20–24 Apr 2026 | 📍 EMBL Heidelberg Co-organised with @banterlegroup.bsky.social @gautamdey.bsky.social 💡 Register your interest to get notified when registration opens: 🔗 www.embl.org/about/info/c...
💼 PostDoc position (2 years) on Trypanosoma brucei | Bordeaux, France | Lab MFP with Dr. Frédéric Bringaud @univbordeaux.bsky.social @cnrsaquitaine.bsky.social 🔬 Glycerol and differentiation in Trypanosoma brucei 🗓️ Deadline: September 15. Start: by November 2025 labex-parafrap.fr/fr/emplois/4...
On Friday, Daniel left us after more than 4 happy years in the lab @pasteur.fr and a great paper published today in @jcellsci.bsky.social as well as other contributions! Many thanks for everything! journals.biologists.com/jcs/article-...
#Trypanosoma, fixed, expanded, and imaged with #STED, stained for tubulin. Scale bar refers to expanded specimen, original structures are 3-3x smaller. Image courtesy: @mbonhivers.bsky.social, MFP, CNRS, Univ. Bordeaux, France #fluorescencefriday #ExM #STEDmicroscopy
🚨 New preprint! Using U-ExM + in situ cryo-ET, we show how C2CD3 builds an in-to-out radial architecture connecting the distal centriole lumen to its appendages. Great collab with @cellarchlab.com @chgenoud.bsky.social @stearnslab.bsky.social 🙌. #TeamTomo #UExM www.biorxiv.org/content/10.1...
Honoured to have been introduced today by former lab member @ebertiaux.bsky.social at the annual Microbiology day of New Aquitaine. My first talk in a (former) church!
#Phosphofructokinase (PFK) is considered an irreversible glycolytic #enzyme. This study shows that #Trypanosomes are the only known organism to use PFK in the gluconeogenic direction under normal conditions, likely due to its compartmentalization within glycosomes @plosbiology.org 🧪 plos.io/43r84Qc
Huge congratulations to @marinelap.bsky.social for receiving the 2025 Young Researcher Award! 🏆👏 sbcf.fr/en/newslette...
