Unless something wonky happens, tomorrow will mark five months of not being misgendered once in my new job. This sense of inclusion is a huge part of why I feel so comfy here, so please consider being equally supportive in your own work environment - a lot of people will appreciate it!

Zandawala lab is looking to recruit a postdoc to work on neuromodulation of feeding in Drosophila and other arthropods at KU Leuven (Leuven, Belgium). Details for the position can be found here: www.kuleuven.be/personeel/jo... Please share!

Postdoctoral Researcher in Neuromodulation of Feeding

We are recruiting a postdoctoral scientist to join the recently opened Zandawala Lab at KU Leuven. The position is funded by an Odysseus grant from FWO (Research Foundation – Flanders). For more infor...

kuleuven.be

Mankees are headed to #CSEE2026! Check out @squarehare.bsky.social's and @joellelafond.bsky.social's talks about Poecilia sex chromosomes, and @vdbijl.bsky.social's talk about evolutionary repeatability of male colour.

So many lovely papers in here - check them out! Very grateful to be part of this network 😊

CIRTN-R2FIC@cirtn.bsky.social · 3mo ago

(🧵 1/22) Many publications from the CIRTN labs this Spring 🌷! Works are from Drs Bruin, MacDonald, Johnson, Mulvihill, Chen, Verchere, Kolic, Huang, Hull-Meichle, Kin, Shapiro, Korbutt, Pepper, P. MacDonald, T. MacDonald, Rideout, Riddell, Rutter, Rabasa-Lhoret and Prentice.

On March 24 & 25, WHRI leaders highlighted BC’s role in advancing women’s health research at the first-ever National Women’s Health Summit, hosted with @pwhrcanada.bsky.social. A conversation with Danièle Henkel explored federal leadership in women’s health and Bill S-243. https://bit.ly/4e0IoRj

The #circadian clock & cellular #metabolism are tightly coupled. Yao Cai & @joanna-chiu.bsky.social explore a @plosbiology.org study showing how #glucose metabolism changes during the day in #Drosophila and how it is disrupted in clock & sleep mutants 🧪 Paper: plos.io/3Olm1M1 Primer: plos.io/4sUov2g

Preconception exposures of female mice to a panel of metabolic disruptors induce sexually dimorphic metabolic perturbations in their offspring #Drosophila

Can a single brain cell decide whether to eat or not? 🧠🪰 Turns out... yes. And we found it in the fruit fly. A pair of neurons called SELKs (subesophageal leucokinin neurons) can drive feeding behavior in both directions. They promote it or suppress it. Here's how: 🧵

I need to work harder, I don't even control my office thermostat....😂

Mine Doğucu@minedogucu.com · 4mo ago

Forget tenure or h-index. I have reached the true mark of academic prestige. This academic term I teach in a classroom where I can control the temperature.

Looking forward to reading this!!

Robert Screaton@roblab.bsky.social · 4mo ago

link.springer.com/article/10.1... New article from the group on the effects of aging and sex in beta cell glucose sensing - ROMO1 and complex II! Thanks to funders @diabetescanada.bsky.social and CIHR.

Beyond delighted to share our amazing collaboration with Thierry Alquier's lab @alquierthierry.bsky.social on a conserved role for neuronal lipid droplets in regulating energy homeostasis in vivo led by Celena Cherian, Romane Manceau, Danie Majeur, and Colin Miller www.nature.com/articles/s42... /1

Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis - Nature Metabolism

In vivo regulation of neuronal lipid droplet formation mediates whole-body energy homeostasis in a sex-specific manner in Drosophila and mice.

nature.com

We have recently updated FlyCyc biocyc.org/DMEL/organis..., the pathway-genome database representing Drosophila metabolism, to include enzymatic complexes as well as further improvements to enzyme annotations. #FlyCyc is now classed as a ‘Tier 1 Highly Curated Organism Database’.

Now published as version of record at @elife.bsky.social ! Layers of Immunity: Deconstructing the Drosophila effector response. The tools are now deposited in the VDRC (link ⬇️) elifesciences.org/articles/107... shop.vbc.ac.at/vdrc_store/d... #Drosophila #IDsky #SymbioSky #Infection #Immunology

Mark A. Hanson@hansonmark.bsky.social · last yr.

Excited to finally announce this work which has been in the pipeline for 5 years: Layers of Immunity. Faustine et al. made a set of immune mutants covering 4 major immune modules in #Drosophila, deleting melanization (ROS), phagocytosis, and both Toll & Imd NF-kB responses. What did we find? 1/n 🧵

✨A gut feeling you’ll love this one 🐛 The anterior midgut of a Drosophila melanogaster 🪰larva puts on a confocal glow show! 🟢 Adult midgut progenitors 🔴 Actin 🔵 Nuclei 📸Image by Sapna Krishnakumar #FluorescenceFriday #Microscopy #DevBio

Islet Biologists in 🇨🇦 🏆 @cirtn.bsky.social

🪰 folks! I spoke to the Transmitter about FlyBase. As noted at flybase.org, bridge $ ran out and many staff were laid off. Good news is stopgap contributions will keep core FlyBase operations active. But community support remains essential. Please donate @FlyBase and share! 1/2 tinyurl.com/FlyBase

FlyBase secures funding for year, but future still uncertain

The FlyBase team’s fundraising efforts have proven successful in the short term, but restoration of its federal grant remains uncertain.

tinyurl.com

📣Tomorrow is International #DayoftheGirl & 30 years since the Beijing Declaration on advancing equity, development & peace for all women & girls 📈We must scale investment in girls — including through research, health, education & empowerment- -a commitment we make in our lab #GenerationEquality

Burgmer, S., Meyer Zu Altenschildesche, F., Gyenis, A., Lee, H., Vilchez, D., Giavalisco, P., Fichant, A., Uhlirova, M., Storelli, G. (2025). Endosymbiont control through non-canonical immune signaling and gut metabolic remodeling. Cell Rep, 44(6):115811 www.cell.com/cell-reports...

Endosymbiont control through non-canonical immune signaling and gut metabolic remodeling

Burgmer et al. show that the pattern recognition receptors (PRRs) PGRP-LC and PGRP-LE repress key metabolic functions in the Drosophila midgut. These regulations occur independently of canonical immun...

cell.com

Another amazing achievement from the fly community 🤩

Greg Jefferis@jefferis.bsky.social · 10mo ago

Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....

💫NEW: @telemanlab.bsky.social & co demonstrate that #AMPK can be activated by signaling metabolite, #adenosine, under non-stress conditions during #Drosophila development. The intestine regulates adenosine levels, thus, remotely controlling wing disc AMPK activation and growth. bit.ly/4gX6njF

Remote control of AMPK via extracellular adenosine controls tissue growth - Nature Cell Biology

Zhang et al. demonstrate that AMPK can be activated by signalling metabolite, adenosine, under non-stress conditions during Drosophila development. The intestine regulates adenosine levels, thus, remotely controlling wing disc AMPK activation and growth.

bit.ly

🪰 More than 750 scientists from 40+ countries gathered in Alicante for the XXVIII European Drosophila Research Conference #EDRC2025. For 4 days, the fruit fly took center stage as a model to study health, aging, and disease👏 @edrc2025.bsky.social @csic.es @dicv.csic.es @umh.es

Thank you to all #EDRC2025 participants and a big applause to the organizing committee for this great #Drosophila meeting! See you all in Bonn for #EDRC2027

EDRC2025@edrc2025.bsky.social · 10mo ago

That’s a wrap! We are done with #EDRC2025 and we look forward to seeing everyone again in 2027 for #EDRC2027 in Bonn!

#edrc2025 European #drosophila Society meeting announces the 2029 meeting location : see you all in Szeged (and Bonn in 2027 of course)!

Beautiful location, fabulous science, and wonderful people 🤩 Thanks to the organizers for all your hard work in bringing us together!

EDRC2025@edrc2025.bsky.social · 10mo ago

We are on day 3 of #EDRC2025 continuing with excellent #Drosophila science

Interesting episode of short wave about the origin of endometriosis. I really appreciate that they end with how uncertainty in NIH funding affects the future of their work. www.npr.org/2025/09/26/n...

What causes endometriosis? Scientists are closer to finding out : Short Wave

Since the age of nine or ten, Katie Burns has had debilitating pain from endometriosis, a condition where tissue resembling the uterine lining grows outside the uterus. For years, Katie was in the dar...

npr.org

2nd paper outta my PhD is NOW PUBLISHED😭 🧬🖥️ 🦑Here we show how comparative #genomics 🧬 is a powerful tool to detect putative #SexDetermination genes: Dmrt1L & SoxH from #bivalves 🦪 share evolutionary patterns with Sry from #mammals 🐗 but not with genes from #drosophila 🪰 doi.org/10.1111/mec....

Taking in my favorite part of Vancouver airport on the way to EDRC in Alicante - excited to see folks there for all things Drosophila!

Dear JEDIs, the #EDRC meeting is coming soon! Who is joining? Looking forward to meeting everyone next week!

Studies of prohormone convertase knockouts in mouse islets reveal plasticity in proglucagon processing to support intra-islet α cell-to-β cell communication, normally dominated by glucagon secretion www.science.org/doi/10.1126/...

α cells use both PC1/3 and PC2 to process proglucagon peptides and control insulin secretion

α cells can generate and secrete both glucagon and GLP-1 with distinct processing enzymes to control metabolism.

science.org

Very proud of Celena Cherian in the lab, who contributed data to www.biorxiv.org/content/10.1... Briefly, Celena showed female fat body cells have higher ribosomal protein expression and more protein synthesis than males. This difference persists even after cell size is accounted for!

Cell type specific allometry controls sex-differences in Drosophila body size

Species and sex-specific differences in organ size are fundamental features of animal biology, yet the mechanisms that drive these differences remain debated. Adult female Drosophila are larger than m...

biorxiv.org