Read about our latest work here www.cell.com/cell/fulltex... or let Alessandro tell you all about it (link below)!

The sex and reproductive plasticity of intestinal muscles instruct gut size

Adult intestinal size plasticity is driven not only by epithelial stem cells but also by remodeling of the surrounding visceral musculature. Sex- and reproduction-dependent muscle remodeling controls ...

cell.com

The Francis Crick Institute@crick.ac.uk · 23h ago

“I believe my findings are just the tip of a bigger iceberg.” Read more about the work from Alessandro, a postdoc in our Organ Development and Physiology Lab led by @irenemiguel-aliaga.bsky.social, who studied changes in the female intestine during and after reproduction: https://bit.ly/4bElX2u

“I believe my findings are just the tip of a bigger iceberg.” Read more about the work from Alessandro, a postdoc in our Organ Development and Physiology Lab led by @irenemiguel-aliaga.bsky.social, who studied changes in the female intestine during and after reproduction: https://bit.ly/4bElX2u

The only good thing about having suffered the hotest June & July ever in France, is that you don't feel too bad visiting Greece in August !

By publishing with eLife, you can support reform in research communication, review and assessment. Want to know what the experience is really like? Hear firsthand from authors who have published with eLife. buff.ly/B8XtSQc

Publishing in the eLife Model: An author’s perspective

Hear from some of our authors about their experience of publishing with us.

buff.ly

I’m thrilled to finally share our work published today in Science Advances! Sometimes the most interesting discoveries come from asking old proteins new questions. www.science.org/doi/10.1126/...

TRF2 couples muscle stem cell identity to regenerative repair

Beyond telomere protection, TRF2 couples stem cell identity to regenerative repair through lineage-specific gene regulation.

science.org

Membrane lipid composition and rapid endocytic retrieval modulate Wingless secretion Ines Alvarez-Rodrigo et al @jpvincentlab.bsky.social link.springer.com/article/10.1...

Membrane lipid composition and rapid endocytic retrieval modulate Wingless secretion - The EMBO Journal

The Wnt family ligands carry a lipid moiety that must be shielded from the aqueous environment. During secretion, this is achieved by the cargo receptor Wntless. The effect of acute endocytosis inhibi...

link.springer.com

What if the next breakthrough in #extracellularvesicle biology comes from a fly? 🪰 Evolution has conserved the core machinery of EV biology, making #Drosophila a powerful platform for discovering mechanisms relevant to human health. 🔗: sciexplor.com/exo/articles... #exosomes

Kudos to @science.org for this self-analysis of the peer review process. These kind of data are never shared and don't have to be. Wildly refreshing to see it out in the open. Editorial and peer review dynamics at elite general science journals | Science Advances www.science.org/doi/10.1126/...

Editorial and peer review dynamics at elite general science journals

Analyses of deidentified data reveal complex interactions that quantify success at elite general science journals.

science.org

Raced home from vacation so we could submit and preprint postdoc @keisukefukumura.bsky.social's paper! It's an exciting first foray for our lab into the periphery, where we find a unique role for CLOCK in regulating lifespan on high fat diet. 🧪https://doi.org/10.64898/2026.07.20.739608

Fat body CLOCK restrains innate immunity and maintains survival under dietary stress in Drosophila

Both aging and a high-fat diet (HFD) dampen circadian gene transcription rhythms and promote chronic inflammation. How aging and HFD interact to affect peripheral molecular clocks and circadian behavi...

doi.org

A multivalent RNA affinity tag enables selective purification of tagged RNAs and bound proteins doi.org/10.1093/nar/...

A multivalent RNA affinity tag enables selective purification of tagged RNAs and bound proteins

Abstract. Efficient purification of specific RNAs from lysates remains a major challenge. Existing methods, such as MS2 tagging or oligonucleotide hybridiz

doi.org

www.nature.com/articles/s41... how cool!

Intestinal stem cells count self-renewal divisions to switch multipotency - Nature

In Drosophila, cell fate switching in adult intestinal stem cells is determined through an epigenetic mechanism in which these cells count divisions, switching from producing enterocytes to producing ...

nature.com

Open position in our lab for a research engineer. The applicant must hold a PhD in life sciences and have demonstrable experience in molecular biology and biochemistry. For more info: emploi.cnrs.fr/Offres/CDD/U...

Institut Jacques Monod@ijmonod.bsky.social · 2w ago

#JobOffer 💼 Research Engineer (M/F) 📆 October 15th 📍Institut Jacques Monod, @sandraduharcourt.bsky.social 🔗 emploi.cnrs.fr/Offres/CDD/U...

Hearing anecdotally that fly grants are getting hammered hard here in 🇨🇦. So I urge you - if you are asked to be a reviewer, please accept and be fair and reasonable - an antidote to ignorant comments and critiques.

I am very pleased to share the latest article from the PHYBAC team, which shows that 1) the loss of function of certain PRC1 subunits leads to the development of a new type of intestinal tumor, and 2) the NF-κB immune pathways act as a brake on tumor progression. journals.plos.org/plosgenetics...

A tumor-suppressive role of the PRC1 Polycomb epigenetic complex in the maintenance of adult Drosophila intestinal stem cell identity

Author summary Our research explores how stem cells in the adult intestine stay healthy and avoid becoming cancerous. We focused on a group of proteins called Polycomb Repressive Complex 1 (PRC1), whi...

journals.plos.org

𝗥𝗶𝘀𝗸𝘀 𝗼𝗳 𝗚𝗲𝗻𝗲 𝗧𝗵𝗲𝗿𝗮𝗽𝘆: 𝗭𝗶𝗹𝗼𝗻𝗴 𝗤𝗶𝘂 𝗼𝗳 𝗦𝗵𝗮𝗻𝗴𝗵𝗮𝗶 𝗝𝗶𝗮𝗼 𝗧𝗼𝗻𝗴 𝗨𝗻𝗶 𝗳𝗮𝗶𝗹𝗲𝗱 𝘁𝗼 𝗱𝗶𝘀𝗰𝗹𝗼𝘀𝗲 𝗱𝗲𝗮𝘁𝗵 𝗼𝗳 𝗮 𝗽𝗮𝘁𝗶𝗲𝗻𝘁 [via Science.org] 🧪🥼🧬✂️⚕️ "did not disclose Mei’s death and the side effects in primates - [or her parents'] financial contribution" www.science.org/content/arti... #gene #editing #therapy #risks

Chinese university launches probe into girl’s gene-editing death

More than a year after failed clinical trial, Shanghai Jiao Tong University School of Medicine promises “serious action”

science.org

#ESR La Cour des Comptes souhaite la poursuite du programme de réformes d'Aghion de 2004: fin des organismes de recherche et du statut de fonctionnaire. La fin (privatisation) n'est pas encore évoquée. www.lalettre.fr/fr/politique...

Inserm, CNRS, Inria : la Cour des comptes propose de sabrer les organismes de recherche au profit des universités - LA LETTRE

Dans un rapport confidentiel, les magistrats de la Rue Cambon préconisent un redéploiement des milliers de chercheurs des grandes structures publiques dans les facultés. Un big bang qui vise à

lalettre.fr

I love biology--after decades of study, we're still learning new and surprising things about one of the best studied reproductive systems, that of the female fruit fly pubmed.ncbi.nlm.nih.gov/42489076/

After about a year from the preprint, our scRNAseq atlas of the developing Drosophila nerve cord has been published in @nature.com www.nature.com/articles/s41...

A global molecular code for birth order and neuronal identity in Drosophila - Nature

A high-resolution developmental transcriptional atlas of the Drosophila melanogaster nerve cord identifies a shared transcriptional code that records neuronal birth order and organizes neuronal d...

nature.com

RNA-binding protein Sxl regulates #SexDetermination & mRNA splicing in #Drosophila. Freya Storer @drflyguyni.bsky.social @tonysouthall.bsky.social &co reveal a new role for Sxl in neuronal homeostasis & tRNA synthesis via Polr3E regulation in #neurons @plosbiology.org 🧪 plos.io/4wRR96l

Does anyone have a list (excel/csv) of journal name | Publisher | current APC? Ideally focussed on the Life Sciences and does not need to be exhaustive. It's for the Play your APCs right game I'm making :)

Hello World ! We have another postdoc position open in the lab! Are you a freshly minted Ph.D. with a passion for chromatin and evolution ? Come join our ERC project #EvoEpi ! Inclusive environment + cool people + great science = success details 👉 tinyurl.com/3r6zk54n Repost are always appreciated

AI in scientific publishing: Slower, worse, and more expensive | Science www.science.org/doi/10.1126/...

AI in scientific publishing: Slower, worse, and more expensive

There’s a saying in the management world, popularized by NASA administrator Daniel Goldin in the 1990s, that the goal of technological improvements is to make products faster, better, and cheaper. Alt...

science.org

L'ANR persiste dans la restriction de l'accès au financement de la recherche, avec notamment de nouveaux critères ridicules introduits sous des prétextes fallacieux pour les PRC. C'est juste pitoyable...

ANR - Agence nationale de la recherche@agencerecherche.bsky.social · 4w ago

🔎 L’ANR publie son Plan d’action et l’Appel à projets générique (#AAPG) 2027 : la recherche guidée par la curiosité reste au cœur des financements de l’Agence et l’articulation avec l’Europe est renforcée. En savoir ➕ anr.fr/Publication-...

In memory of Pierre Chambon (1931–2026): a visionary pioneer of modern molecular biology by Hinrich Gronemeyer in @embojournal.org link.springer.com/article/10.1...

In memory of Pierre Chambon (1931–2026): a visionary pioneer of modern molecular biology - The EMBO Journal

The EMBO Journal -

link.springer.com

New paper 🧵 What if the "landscape" that guides cell differentiation isn't fixed, but is sculpted, in real time, by the very cells moving through it? We call this a 'sandscape' : grains of sand that carve dunes as they move, while the dunes' shape simultaneously steers where the grains go next.

Alright this is the bat signal that if you’re in Paris and want to meet yell in my direction! We are taking press, meeting with local scientists, and talking science and democracy all week ✊🏼

Dear fellow researchers. I think we need to discuss this: www.newscientist.com/article/2532... While peer review is flawed, and while preprints are a great way to share data before publication, as a community we mustn’t trade rigour for hype. This paper was peer reviewed and rejected.

What is 'SpudCell'? Arguably the greatest bioengineering feat yet

A prototype cell partly capable of replicating itself has been created using 36 existing bacterial genes, but it's not really a living organism – yet

newscientist.com

Juin 2026 a été le mois de juin le plus chaud enregistré dans l'Hexagone, avec des records absolus de l'indicateur thermique national 🇫🇷 @meteofrance-n.bsky.social 1/...

How do dozens of distinct muscles emerge from the same pool of precursor cells? Our new Science Advances paper uncovers the developmental logic that coordinates myoblast identities to build diverse muscles. 📄 www.science.org/doi/10.1126/... #DevelopmentalBiology #Drosophila #Muscle

Spatiotemporal control of myoblast identity drives muscle diversity in the Drosophila leg

This study reveals how muscle diversity arises in flies, enabling the complex movements that drive animal behavior.

science.org

Alerte désinformation : non, il n'a pas fait 45°C à l'ombre en 1870 www.linkedin.com/pulse/canicu...

Canicule : la fabrique de la désinformation

Au Sénat, le 29 juin 2026, lors de l'ouverture du débat sur le projet de loi agricole, le Sénateur Laurent Duplomb déclare, "je n'oublie pas non plus George Sand écrire en juin 1870 que sous des tempé...

linkedin.com