Hi friends & colleagues! I’m on the hunt for a tenure-track home! I’m a BRAIN Initiative K99/R00 scholar studying learning & memory at the intersection of experimental neuroscience, theory, & machine learning/AI. I’d love to connect & would appreciate help spreading the word! web.mit.edu/hsw/www/

With the beginning of the new academic year, I'm reposting the info for our free online neuroscience methods course. If you're starting a PhD in neuroscience, or just want a refresher, this is for you!

Luke Sjulson@lukesjulson.bsky.social · 2y ago

Neuroscience students asked us to teach a PRACTICAL course on experimental methods, and it is now on YouTube! Please like and repost to help us get the word out! www.youtube.com/playlist?lis... Lecture 1: Signals and data acquisition Focusing on hardware, digital/analog I/O, synchronization 🧵

After a long journey through review, our paper is finally out in Nature Communications. We started with a simple problem: The visual cortex is strongly modulated by movement. So how can it represent the visual world without movement interfering with everything? www.nature.com/articles/s41...

We had a great seminar today at RU with @ginapoe.bsky.social Very compelling and interesting argument that REM sleep is important for memory consolidation (btw no ripples during REM) Also super cool hypothesis on heterosynaptic plasticity during different brain states

Listened to this while fixing the mesoscope and it's a great interview. Dan has lots of interesting views in neuro and neuroAI

The Transmitter @thetransmitter.bsky.social · 2w ago

In this episode of @braininspired.bsky.social, @dlevenstein.bsky.social explains how internally generated brain activity during sleep shapes our cognition, and why NeuroAI is such a powerful approach to understanding our brains. #neuroskyence www.thetransmitter.org/brain-inspir...

TFW you fix a normalization term and all the results start to come together

Nicolas Cage Feels Good in Space

ALT: Nicolas Cage Feels Good in Space

static.klipy.com

Very cool finding from Roman in Gyuri's lab on how preconfigured hippocampal circuits can encode new locations. Also really nice to see gcPCA helping reveal meaningful biological structure in the data! www.cell.com/neuron/fullt...

Developmentally defined subcircuits in the hippocampus support spatial learning

Huszár, Kirsanov et al. show that hippocampal CA3 and CA1 neurons born on the same day form a functional subcircuit that encodes new memories. Spatial learning engaged convergent connectivity from emb...

cell.com

This is very interesting

Andrew MacAskill@macaskillaf.bsky.social · 4w ago

Congrats @jespass.bsky.social on her new paper! PFC is widely thought to talk to HPC via nucleus reuniens - but no one has tested if this actual connectivity exists. Turns out it's wired to block it: PFC inputs to reuniens contact only neurons projecting back to PFC, not ones projecting to HPC. 🧪🧠📈

In mice, hibernation causes the loss of more than 50% of all hippocampal synapses. But after recovery, memories are preserved and most of the 'lost' synapses grow back! www.science.org/doi/10.1126/... "Somehow, the synapse returned."

Artificial hibernation reveals synaptic engram architecture associated with memory retention

Memories leave lasting physical changes at the synaptic level. Although stable, larger spines are thought to support memory, the high turnover of dendritic spines and the drifting of neuronal represen...

science.org

Developmentally defined subcircuits in the hippocampus support spatial learning www.cell.com/neuron/fullt...

Developmentally defined subcircuits in the hippocampus support spatial learning

Huszár, Kirsanov et al. show that hippocampal CA3 and CA1 neurons born on the same day form a functional subcircuit that encodes new memories. Spatial learning engaged convergent connectivity from emb...

cell.com

How it feels when they ask for an extra recommendation letter you didn't plan for

This is why I keep my glasses on.

We released gcpca on CRAN for R users working with high-dimensional experimental data. gcPCA identifies low-dimensional patterns enriched in one condition relative to another, without tuning hyperparameters. 🧠 📈 Package, tutorials, and examples are available here: eliezyer.github.io/gcpca/

I always wanted an excuse to own a crowbar and the right crate just arrived in our lab

The Orange Cat Brain Atlas is here. 🧠🐈 Today, we published the first comprehensive cellular map of the orange cat brain. The new atlas reveals a single, specialized neuron responsible for behaviors like staring at walls, knocking objects off tables, and the 3am "zoomies."

I watched Project Hail Mary with some friends and we all loved the movie, but all the science folks lost it over a 2s scene of an unbalanced centrifuge. That's to show the shared trauma we have for experiencing this equip going at thousands rpm while wobbling in place

Obsessed with this band that dresses like a psychophysical stimulation protocol youtu.be/0Ssi-9wS1so

Angine de Poitrine - Full Performance (Live on KEXP)

YouTube video by KEXP

youtu.be

Catching up on #Cosyne2026 talks online. The lineup of talks this year is really strong across topics! I'm having some FOMO watching these remotely

Another perspective: someone's career can be delayed or completely ended because of delays in review. Who is to blame when reviewing papers is seen as a burden?

The Transmitter @thetransmitter.bsky.social · 7mo ago

Broad peer review is crucial for a healthy scientific literature, but neuroscientists turn down review requests too often. Simple math suggests that small groups of scientists can significantly bias the literature, writes @jvoigts.bsky.social. #neuroskyence www.thetransmitter.org/publishing/l...

Despite all my rage, I'm still just a rat in space

DANDI Archive@dandiarchive.org · 7mo ago

Mission: record hippocampal place cells in zero gravity Crew: 3 rats with electrode arrays Vehicle: Space Shuttle Columbia Status: data now publicly available on DANDI, 28 years later The ratstronauts' mission is finally complete. 🐀🚀 h/t NASA about.dandiarchive.org/blog/2026/02...

Dendritic arbors provide neuroscience with an ideal opportunity to study how individual neurons interact with their broader circuitry and are the field’s best bet to bridge cellular and systems neuroscience, writes @justinkohare.bsky.social. #neuroskyence www.thetransmitter.org/dendrites/de...

Dendrites help neuroscientists see the forest for the trees

Dendritic arbors provide just the right scale to study how individual neurons reciprocally interact with their broader circuitry—and are our best bet to bridge cellular and systems neuroscience.

thetransmitter.org

With this one in print, I think I finally earned that PhD... 😅 Presented for the first time at the cosyne when the world ended (March 2020). I'll bring over a summary thread from twitter when it was still twitter... www.sciencedirect.com/science/arti...

Neuronal spiking in the mammalian forebrain is dominated by a heterogeneous ground state

Neuronal firing patterns have significant spatiotemporal variability with no agreed-upon theoretical framework. Using a combined experimental and mode…

sciencedirect.com

Thrilled to finally share this work! 🧠🔊 Using a new reinforcement-free task we show mice (like humans) extract abstract structure from sound (unsupervised) & dCA1 is causally required by building factorised, orthogonal subspaces of abstract rules. Led by Dammy Onih! www.biorxiv.org/content/10.6...

Our paper is out in @natneuro.nature.com! www.nature.com/articles/s41... We develop a geometric theory of how neural populations support generalization across many tasks. @zuckermanbrain.bsky.social @flatironinstitute.org @kempnerinstitute.bsky.social 1/14

Please share: we're hiring a new tenure-track faculty member to our Department of Genetics at Albert Einstein College of Medicine. faculty-einstein.icims.com/jobs/17847/a...

New paper out at PNAS: www.pnas.org/doi/10.1073/... Revisiting the high-dimensional geometry of population responses in the visual cortex with @jpillowtime.bsky.social. The review took forever because a reviewer was doubtful our new estimator can infer eigenvalues beyond the rank of the data! (1/6)

I just thought everyone should see this

A humble proposal: all abbreviations in scientific papers should use PDF tooltips to expand the abbreviation when the mouse pointer hovers over them. Anyone agree/disagree?

Just watched the new Knives Out and I think it's really important you know that the scene in the Seminary's Gym is filmed in the same place Rick Astley filmed the music video for Never Gonna Give You Up. I saw the window tracery and immediately made my friends pause the film so I could tell them.