Alright now that I’m home I guess it’s time to officially announce some really good news: I have received an NIH R35 MIRA!! This award will fund five years of research in my group using Aiptasia to study context dependency and GxGxE interactions in animal-microbe symbioses!
Emily Meier
@emilykmeier.bsky.social
Doctoral student studying the cnidarian immune system and host-microbe interactions that establish symbiosis. 🪸🦠 Cleves Lab @ UC Berkeley • MCB • PADI Divemaster 🌊
The prestigious Miller Research Postdoctoral Fellowship is open! University of California, Berkeley This is a postdoc fellowship with substantial support and independence to be hosted at a lab at Berkeley, reach out with interests! miller.berkeley.edu/nominate-app...
Miller Research Fellowship | Miller Institute for Basic Research in Science
miller.berkeley.edu
We have shared detailed protocols for the expression, purification, and use of VitelloTag-Cas9 (in sea stars) on our website. We hope that this will be a useful starting place for working in your own favorite organism! www.theswartzlab.org/tools-and-pr...
Tools and Protocols — Swartz Lab @ The Marine Biological Laboratory
theswartzlab.org
At last! The plasmids from our VitelloTag paper ( journals.biologists.com/dev/article/... ) are now available on Addgene: www.addgene.org/browse/artic... We hope they might be useful for you to deliver Cas9 in your favorite organism. Stay tuned for detailed protocols on our lab website.
Out @cp-cellhostmicrobe.bsky.social, natural products meet bacterial immunity! We used genomics to identify lanthivirins: a family of >2,000 lanthipeptide BGCs that protect Actinobacteria against phages. Led by @hshomar.bsky.social & @mariegllm.bsky.social www.sciencedirect.com/science/arti...
A family of lanthipeptides with anti-phage function
Bacteria produce natural products to adapt to their environments, with phage interactions as major ecological and evolutionary drivers. While some nat…
sciencedirect.com
A fully updated preprint is now live on @biorxivpreprint.bsky.social :) “Look and see” was a rather important line of thinking regarding freshwater sponge-microbe interactions, centering on the importance of spatial dynamics when evaluating animal microbiomes 🧽🦠🧪 www.biorxiv.org/content/10.6...
My flight to Auckland got delayed by 24 hours, but I'll make it just in time for my talk at ICRS - Monday at 10:45AM in room 516! This is my first ICRS, very excited! #ICRS2026
I’m happy to share our pre-print exploring the activity and specificity trade-offs in adenine base editors. Thanks to my amazing co-authors Luke Oltrogge, @hnisonoff.bsky.social, and all the other contributors @jlistgarten.bsky.social @savagecatsonly.bsky.social @innovativegenomics.bsky.social 🧵1/7
Activity and specificity trade-offs in adenine base editors
Adenine base editors (ABEs) are CRISPR effectors that introduce A-T to G-C transitions in the genome using a nucleotide deaminase fused to a Cas protein. ABEs have been evolved to have very high editi...
biorxiv.org
Check out our new preprint on base editors and the thread below!
I’m happy to share our pre-print exploring the activity and specificity trade-offs in adenine base editors. Thanks to my amazing co-authors Luke Oltrogge, @hnisonoff.bsky.social, and all the other contributors @jlistgarten.bsky.social @savagecatsonly.bsky.social @innovativegenomics.bsky.social 🧵1/7
“Unfortunately, in 2023, an acute heating event, when water temperatures exceed the maximum monthly mean SST by 2.5 C for many weeks, led to the extinction of wild and replanted corals on the Florida Keys.” — Caroline Ash www.science.org/doi/10.1126/...
Heat-driven functional extinction of Caribbean Acropora corals from Florida’s Coral Reef
In 2023, a record-setting marine heat wave triggered the ninth mass coral bleaching event on Florida’s Coral Reef (FCR). We examined spatial patterns of heat exposure along the ~560-kilometer length o...
science.org
Congrats to the team!! 🪸 🦠 🧬 academic.oup.com/genetics/adv...
Development of genetic tools for the sea anemone Aiptasia, a model system for coral biology
Abstract. The reef-building corals can thrive in nutrient-poor waters because of the mutualistic symbiosis between the animal hosts and their photosyntheti
academic.oup.com
My group is hiring a new Postdoc to work on gene regulation and chromatin in Nematostella. Please RT! For more information see here: gahanlab.com tinyurl.com/34xke35d
For grad students and postdocs: We'd love to see you at the Molecular and Cell Biology of Symbiosis course at the Marine Biological Labs this summer! Application deadline is Apr 14, so apply soon. Please share with anyone who might be interested! www.mbl.edu/education/ad...
Molecular and Cell Biology of Symbiosis | Marine Biological Laboratory
This is an immersive research-based course designed to teach basic concepts, open research questions, and facilitate state-of-the-art experimental approaches in symbiosis research.
mbl.edu
#weekendreading🔬📑 Tissue-like multicellular development triggered by mechanical compression in archaea @science.org #microsky www.science.org/doi/10.1126/...
Tissue-like multicellular development triggered by mechanical compression in archaea
The advent of clonal multicellularity is a critical evolutionary milestone, seen often in eukaryotes, rarely in bacteria, and only once in archaea. We show that uniaxial compression induces clonal mul...
science.org
And... it's live! In situ hybridization has been foundational for sea urchin developmental biology. Here we report a fully automated method to probe more than a hundred genes using a general purpose liquid handler.https://www.biorxiv.org/content/10.1101/2025.03.23.644641v1
Make like a nudibranch and slooow down in our latest installment of Krill Waves Radio! 🎧 Settle with spectacular sea slugs as they sway to soothing lo-fi beats: www.youtube.com/watch?v=FOeQ...
2 Hours of Nudibranchs to Relax/Study To! | Lofi Hip Hop | Monterey Bay Aquarium Krill Waves Radio
YouTube video by Monterey Bay Aquarium
youtube.com
It’s live! Check out the Cleves Lab website and learn how the lab uses ecologically relevant cnidarian models to gain key insights into how microbial symbiosis and its breakdown impact animal biology and health, driving new coral conservation efforts. 🪸🎉 @pcleves.bsky.social www.cleveslab.org
The Cleves Lab
The Cleves Lab researches the molecular, cellular, and developmental basis of how intracellular beneficial microbes invade and persist in animal cells to form symbiosis. They use ecologically critical...
cleveslab.org
OUT NOW: Inducible transposon mutagenesis identifies bacterial fitness determinants during infection in mice #microsky 🧪 www.nature.com/articles/s41...
Inducible transposon mutagenesis identifies bacterial fitness determinants during infection in mice - Nature Microbiology
InducTn-seq, a method for inducible mutagenesis followed by transposon insertion site sequencing, enables temporal control of transposition to bypass population bottlenecks and enable the quantificati...
nature.com
Single-molecule live-cell RNA imaging with CRISPR–Csm - @doudna-lab.bsky.social @qb3-berkeley.bsky.social @innovativegenomics.bsky.social go.nature.com/3EJPKsM
Single-molecule live-cell RNA imaging with CRISPR–Csm - Nature Biotechnology
Single-molecule live-cell fluorescence in situ hybridization uses an RNA-targeting CRISPR–Csm complex to image and track endogenous RNAs.
go.nature.com
Symbnet PhD Summer School on Host-Microbe Symbioses - Oeiras Portugal. Students from all over the world are eligible, we sponsor selected students. Please Repost! gimm.idloom.events/phd-summer-s...
PhD Summer School on Host-Microbe Symbioses 2025
Symbnet PhD Summer School on Host-Microbe Symbioses Gulbenkian Institute for Molecular Medicine (GIMM) & Católica Biomedical Research Centre (CBR) July 06...
gimm.idloom.events