First *complete* view of the mouse hippocampus with in-vivo 2p imaging + ex-vivo MERSCOPE spatial transcriptomics! * 🔊 sound on Amazing collaboration led @jason_hc_yong at @attila_losonczy's lab. Preprint: biorxiv.org/content/10.648 98/2026.04.07.716935v1 Interactive website: shorturl.at/nCaAn

Two-photon calcium imaging at 24,000 lines/s, with the resonant axis spanning 4x what other systems can do. Inertia-free. Diffraction-limited. No tradeoffs. Che-Hang Yu developed a 4x angle multiplier for laser scanning. His paper is out today: opg.optica.org/optica/fullt... 1/n #fluorescenceFriday

Very excited to post our paper led by @daburke.bsky.social www.nature.com/articles/s41... where we uncover a simple mathematical rule underlying how brains learn that a cue predicts a reward. 1/26

Duration between rewards controls the rate of behavioral and dopaminergic learning - Nature Neuroscience

Cue–reward learning rate scales proportionally with the time between rewards. Consequently, learning over a fixed duration is independent of the number of trials. This challenges trial-based dopamine ...

nature.com

I had a special & lovely visit to my alma mater NYCU to give a talk on my PhD work this week. Huge thanks to Dr. Tsai-Wen Chen and Dr. Bei-Jung Lin for hosting me! So excited to see some super cool voltage imaging rig and data 🤩😍⚡ Can't wait to see more sys neuro work from Taiwan!! 🧠

𝗛𝗼𝘄 𝗱𝗼 𝗯𝗿𝗮𝗶𝗻 𝗮𝗿𝗲𝗮𝘀 𝗿𝗲𝗹𝗮𝘁𝗲𝗱 𝘁𝗼 𝗳𝘂𝗻𝗰𝘁𝗶𝗼𝗻? "High-resolution activity maps of PFC did NOT align with cytoarchitecturally defined subregions." Key tenet in neuroscience is that cytoarchitectonic boundaries correspond to functional ones. NB: study in the mouse #neuroskyence doi.org/10.1038/s415...

⚠️ New paper alert and what a way to end 2025! 🎉 Happy to share our story “Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals.” published today in Nature Neuroscience. Sleeping dragons 🦎 and functional ultrasound! Read the full paper here: rdcu.be/eWJHb 1/8

Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals

Nature Neuroscience - Bergel et al. show that an infraslow rhythm connecting the brain and body during sleep is shared by lizards, mammals and birds, revealing an ancestral process and reshaping...

rdcu.be

Posters printed (5x), talks made (2x), symposia chairing ironed out (2x), preprint posted (1x), whole lab on board (7x): 𝐁𝐢𝐥𝐛𝐚𝐨, 𝐡𝐞𝐫𝐞 𝐰𝐞 𝐜𝐨𝐦𝐞! #ECRO2025 🇪🇸🧠👃 ecro2025.com @chloeg-neuro.bsky.social @harinw.bsky.social @connordoyle.bsky.social @ailiemcwhinnie.bsky.social @neurosana.bsky.social

🧠🔄 #NeuroThursday Loops paper! 💡 @hunglo.bsky.social, Friedrich Johenning & team show that during binge feeding, OT GABA neurons silence piriform cortex → flavors fade, fullness lags and eating continues! Who knew smell circuits could fuel overeating? 🐭🧋 🔗 www.sciencedirect.com/science/arti...

Feeding-induced olfactory cortex suppression reduces satiation

Binge feeding commonly leads to overeating. Experiencing flavor during food consumption contributes to satiation. Still, the interactions between flav…

sciencedirect.com

New in Neuron: “Feeding-induced olfactory cortex suppression reduces satiation” @CharitéBerlin researchers. This study reveals how the sense of smell controls meal ending & binge eating behavior. Read more: tinyurl.com/227dw782 #Neuroscience #Satiation #BingeEating @hunglo.bsky.social & colleagues

Feeding-induced olfactory cortex suppression reduces satiation

Lo et al. show that binge feeding suppresses piriform (olfactory) cortex activity, reducing the brain’s representation of food flavor. This suppression is driven by the olfactory tubercle and promotes...

tinyurl.com

🚨 Preprint alert! 🚨 Can mice estimate the distance to an odour source? New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself. Spoiler alert: Yes, they can! Read the paper here: bit.ly/43A9tF9 Short 🧵 below

I'm more than psyched to share that my PhD paper is now out in Neuron! It's also my first paper as both first author and corresponding author, which means even more to me! Thank my partner Chi-Chieh for her contribution to the most adorable ever graphic abstract 🥰

Great work from @facuumm.bsky.social and @ggirardeau.bsky.social ! Interesting that the cell assemblies activity is so sparse!

Juan Facundo Morici@facuumm.bsky.social · last yr.

Hello folks! New update on our bioXriv preprint! With my amazing supervisor @ggirardeau.bsky.social , and the super team @belalima-paiva.bsky.social @azulsilva.bsky.social & Ele www.biorxiv.org/content/10.1... 🧵1 of 4

Hello folks! New update on our bioXriv preprint! With my amazing supervisor @ggirardeau.bsky.social , and the super team @belalima-paiva.bsky.social @azulsilva.bsky.social & Ele www.biorxiv.org/content/10.1... 🧵1 of 4

Dorso-ventral hippocampus neural assemblies reactivate during sleep following an aversive experience

The integration of spatial and emotional components into episodic memory relies on coordinated interactions between hippocampal circuits and emotion-processing regions. While the dorsal hippocampus (d...

biorxiv.org

Neuropixels and Optogenetics are delighted to announce the birth of Neuropixels Opto Combining high-resolution electrophysiology and optogenetics Today in bioRxiv 960 sites, 28 emitters, 2 colors By Lakunina, @karolinazsocha.bsky.social, Ladd, et al www.biorxiv.org/content/10.1... (1/2)

🌟 Exciting News!🌟 I am thrilled to announce that the interdisciplinary symposium Scent and Imagination will take place on the 4th June 2025 in Cambridge (UK)! 🎉 Join us as we dive deep into the complex relationship between olfactory heritage and imagination 🌸💡

We have a fresh new paper! The PhD project of the talented Mark Conway. A learning-induced change in the sensitivity of olfactory receptor neurons enables consistent perception of an odor. #olfaction #neuroscience www.science.org/doi/10.1126/...

Perceptual constancy for an odor is acquired through changes in primary sensory neurons

Learning-induced changes in primary sensory neurons support concentration-invariant perception of an odor.

science.org

I recently created this account and figured I should make an introductory post. I'm a Ph.D. candidate interested in all things neuroscience, although primarily involved in systems and computational aspects of the brain for the moment. Looking to connect with the neuro folks in here! #neuroscience

a man wearing glasses and a red jacket says allow myself to introduce

ALT: a man wearing glasses and a red jacket says allow myself to introduce

media.tenor.com

Everyone knows that failure is bad. We devote a lot of time to trying to avoid it. But sometimes failure is good. A brief story: ~11 yrs ago, when my friends were all starting their own labs, I was starting my 2nd postdoc. My 1st postdoc (w/ Gord Fishell at NYU) had ended in disaster when 1/

オプシンの人たちはどこにいるの？ Where are all the opsin people? Let me know if you want to be listed! go.bsky.app/DXgqJYs

A moment in time: Dieter Oesterhelt passed away in Münich on this day (November 28) in 2022. He identified the 1st microbial rhodopsin more than 50 years ago, with far-reaching impact that could hardly have been imagined. laskerfoundation.org/in-memoriam-...

Just In case people need to follow people in neuroscience focused on natural behaviors and the brains of cool non-trad animals! Please join let me know if you wanna be added. go.bsky.app/AcLpM4h

14 spots left in our *Behavioral and Preclinical Neuroscience* 🐾🧠 starter pack! Thank you to everyone motivated to join! Gathering these scientists would create the perfect institute! ✋ if you wanna join. 🧪🐭 go.bsky.app/7cNykut

Finally finding some time to read through the chaos. Mitral cells will prioritise the soma as spike initiation site upon weak stimuli from olfactory sensory neurons. However, when the stimulus is stronger, they switch to the dendrite! Cool stuff from 2002!

A bit late to the Bluesky party but here’s our work showing a coordinate system for behavioural space, and an algorithm for computing behavioural sequences in the mFC: www.nature.com/articles/s41...

A cellular basis for mapping behavioural structure - Nature

Mice generalize complex task structures by using neurons in the medial frontal cortex that encode progress to task goals and embed behavioural sequences.

nature.com

My lab studies both lab mice and naked mole rats. There is a belief amongst some that what we discover in mice will be universally true, and what we discover in naked mole rats will be a weird mole rat quirk. I believe this mouse-centric view of biological systems is very limiting.

I made a systems neuroscience starter pack, focused on experimentalists who study the brain at the level of populations of neurons! Also want to be on the list? Reply or DM me a picture of your ephys rig or 2p setup and I'll add you 🤭 go.bsky.app/UiqX7ry

A stunning finding from human cortex: SST inhibitory neurons lost first in Alzheimer's... even earlier than excitatory neurons. Thanks to NIH BRAIN (BICCN, BICAN), @alleninstitute.bsky.social and a huge team of investigators (50+ NIH awards), well done for 🧠 science! doi.org/10.1038/s415...

www.biorxiv.org/content/10.1...

A novel rhodopsin-based voltage indicator for simultaneous two-photon optical recording with GCaMP in vivo

Genetically encoded voltage indicators (GEVIs) allow optical recording of membrane potential from targeted cells in vivo. However, red GEVIs that are compatible with two-photon microscopy and that can...

biorxiv.org

I would appreciate it if you could share this invitation and respond if you would like to join this group. go.bsky.app/DXdNa8k

I made a starter pack for the Society for the Study of Ingestive Behavior #SSIB for all interested in being a #SSIBling. Please let me know if you would like to join the starter pack! go.bsky.app/8Zvp83e