Jeff Martin

@jeff.cuchazinteractive.org

Making a better internet for myself and friends. Software engineer working in academia, and on my own tools, in Rust, Kotlin, Mojo, Python, Javascript, and more. Works on nextPYP: software for analyzing CryoET (and EM) data from your web browser.

Interested in a career in industry cryoEM? We're hiring! We seek a cryoEM/cryoET expert to join our team at Genentech advance our mission to provide high-resolution structural insights into biological macromolecules involved in health and disease. Apply at: careers.gene.com/us/en/job/20...

Systems Specialist II in South San Francisco, California, United States of America | Manufacturing & Engineering at Genentech

Apply for Systems Specialist II job with Genentech in South San Francisco, California, United States of America. Manufacturing & Engineering at Genentech

careers.gene.com

Here is an insane piece of lore inside SQLite's source code I am researching VACUUM and I was studying their code. In VACUUM, SQLite creates a temp file prefixed with `etilqs_` Here is why:

** 2006-10-31:  The default prefix used to be "sqlite_".  But then
** Mcafee started using SQLite in their anti-virus product and it
** started putting files with the "sqlite" name in the c:/temp folder.
** This annoyed many windows users.  Those users would then do a 
** Google search for "sqlite", find the telephone numbers of the
** developers and call to wake them up at night and complain.
** For this reason, the default name prefix is changed to be "sqlite" 
** spelled backwards.  So the temp files are still identified, but
** anybody smart enough to figure out the code is also likely smart
** enough to know that calling the developer will not help get rid
** of the file.
*/
#ifndef SQLITE_TEMP_FILE_PREFIX
# define SQLITE_TEMP_FILE_PREFIX "etilqs_"
#endif

🚨🚨🚨JOB ALERT🚨🚨🚨 The Image Analysis Unit at Human Technopole in Milan is recruiting for two positions to join our growing team: 1) Bioimage Analyst 2) Research Software Engineer (RSE) Read on to learn why one of these two people should be you!

“think about whether some of the proprietary license money you’re currently spending could be spent instead on open solutions that would be yours forever, endlessly adaptable, and benefit the entire world. And please get in touch by emailing info@image.coop” 👏 👏 👏 Can’t wait to see where this goes

Image Cooperative@image.coop · 5mo ago

Hello, world! We are starting a worker cooperative to build, maintain, teach, and support open source scientific imaging software. image.coop/blog/posts/2...

When someone says „Scientists do not want you to know“ you can dismiss everything from there on. Scientists want you to know. They are desperate that you know. They can’t shut up about what they found out and want you to know.

its amazing how chatgpt knows everything about subjects I know nothing about, but is wrong like 40% of the time in things im an expert on. not going to think about this any further

Please spread the word: the Structural Studies Division @mrclmb.bsky.social is looking for a new tenure-track, independent group leader with an exciting plan in any area of Structural (Molecular & Cell) biology, in discovery biology and/or methods development. 🥳 mrc.tal.net/vx/mobile-0/...

Research Group Leader Tenure Track - Structural Studies - LMB 2775 - Medical Research Council

Location: Cambridge. Vacancy: Research Group Leader Tenure Track - Structural Studies - LMB 2775. Closing Date: 16/03/2026, 23:55

mrc.tal.net

I brewed my first homebrew beer in nine years today! Damn, it's been a while. It's a dark English mild. If breweries won't make the beers I like anymore, guess I'll do it myself. If you're interested, read more on my other account. Since I'm too lazy to copy it here. gladtech.social/@cuchaz/1160...

Jeff Martin (@cuchaz@gladtech.social)

I brewed my first batch of #homebrew beer in nine years today. (Any homebrewers on here?) Somehow, I still remember how to do it. Feels good to brew again after so long. :blobcat_nwn: The breweries...

gladtech.social

I just got this banger AI-generated spam: "We can potentially arrange for 2 million to 35 million ... Our consortium of single-family offices and HNW individuals are seeking fresh investment opportunities inside the minecraft modding category" There's not much money in Minecraft mods. I LOL'd.

If you're reading my posts or following me because of @altnoaa recommending Session over Signal and folks linking to my blog post criticizing Session: Hi, I'm Soatok. I'm a gay furry who gets angry at arrogant techbros that put people's lives and safety at risk with poor security advice.

Jane Richardson was born #OTD in 1941 + Developed the Richardson (ribbon) diagram to represent proteins' 3D structure (becoming a standard representation for protein structures) + MacArthur Fellow, 1985 + Elected, Nat'l Academy of Sciences, 1991 + President, Biophysical Society, 2012 #WomenInSTEM

Vibrant color portrait of Jane S. Richardson, the visionary biophysicist and artist who revolutionized structural biology with her invention of ribbon diagrams. She gazes warmly at the camera with a bright, knowing smile that radiates quiet brilliance and decades of curiosity. Her silver-blonde hair woven with gentle waves. Large, elegant dangling earrings catch the light, and she wears a richly patterned brown blouse embroidered with intricate turquoise paisley motifs and delicate beadwork that echoes the molecular elegance she has spent her life depicting. Behind her floats a luminous, dreamlike backdrop of glowing molecular structures--interlocking hexagonal and ribbon-like forms in electric blues, teals, and greens--blending science and art in a single, living canvas.Hand-drawn and hand-colored (by Jane Richardson) scientific artwork known as a Richardson ribbon diagram (or “ribbon model”), one of the iconic visual inventions of Jane Richardson that transformed the way we see and understand protein structures. A graceful, three-dimensional tangle of protein backbone ribbons twists and spirals through space, rendered in soft pencil lines and luminous watercolor hues. Smooth golden-brown coils represent α-helices that curl like elegant ribbons, while broad teal-green arrows trace the flat, pleated strands of β-sheets slicing through the molecule with directional purpose. Thin, looping golden threads connect the secondary structures, creating a delicate, almost dance-like choreography of biology’s hidden architecture. The entire form is framed by a simple olive-green mat and dark border, giving the drawing the quiet dignity of both fine art and precise scientific illustration—a timeless bridge between molecular reality and human imagination.

After months of hard work learning a new programming language (it's Mojo) and porting some already-optimized C++ code to it, it feels amazing to finally get that big payoff where the new code is 6 times faster! 😀