Juliette Mathieu

@jujumathieu.bsky.social

Drosophila germline with JR Huynh and choanoflagellates bridges with T Brunet.

Open call! The Genetics and Developmental Biology Department at Institut Curie-Paris is looking for a new Junior Group Leader. Ready to launch your own lab in a vibrant, collaborative environment? We’d love to hear from you. Deadline: Dec 18 👉https://jpi-recruitment-curie-umr3215-u934.curie.fr/

Our study on DFCP1 and lysosome membrane repair is live! We uncover a previously unrecognized role for omegasomes in the cellular response to lysosomal membrane damage, revealing another layer of regulation in how damaged lysosomes are repaired. www.nature.com/articles/s41...

DFCP1-containing ER microdomains mediate lysosomal membrane repair - Nature Cell Biology

Radulovic et al. show that phosphatidylinositol 3-phosphate (PI3P), produced by the phosphatidylinositol 3-kinase PIK3C3, is formed on ER domains after lysosome damage. ER domain PI3P helps to recruit...

nature.com

Here is a new optogenetic tool developed by the Wang's lab @cbitoulouse.bsky.social in collaboration with us to shine light on nuclear protein's function. Using this tool, we discovered (among other things) a role for dLsd1 in border cell migration. Thanks to all the authors for their contribution!

Journal of Cell Biology@jcb.org · 3mo ago

Using NLS-LARIAT in #Drosophila ovarian cells, Liu, @luisadistefano.bsky.social, Wang et al. reveal how rapid inhibition & clustering of GFP-tagged nuclear factors regulate border cell migration, nuclear mechanics, & the cell-fate consequences of nuclear protein dosage. rupress.org/jcb/article/...

Excited to share our newest work! We asked whether RNA molecules need to be in a specific place in the cell to do their job. We found that a single RNA must reach the midbody, the structure that pinches two dividing cells apart, for cell division to finish efficiently. 🧵⬇️

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