Julia Muenzner
@juliamuenzner.bsky.social
Aneuploidy and systems biology in yeasts // using -omics on natural isolate collections 🦠💻 Postdoc with Markus Ralser @Charite in Berlin. Mom of three. she/her
🔥 Published today, and just in time for summer conferences, here are your guidelines for presenting badly www.nature.com/articles/s41... rdcu.be/fqa92
Our paper "Gene ancestries reveal diverse microbial associations during eukaryogenesis.” is finally out in Nature. Eukaryogenesis was likely a gradual process shaped by multiple microbial partners and virus-mediated gene transfer, rather than a single binary symbiosis. doi.org/10.1038/s415...
An important Nature Outlook article from Nic Fleming on antifungal resistance: www.nature.com/articles/d41...
Antifungal resistance is growing – will new treatments turn the tables?
Trials of drugs to fight deadly resistant infections are advancing, but they might fall victim to overuse of agricultural fungicides just like their predecessors.
nature.com
It's been a long time coming to finally see this in print! While not the first paper from my lab, it is one of the very first projects we started working on from day 1 links.springernature.com/f/a/1IP7gCfA...
Pooled CRISPRi screening reveals fungal-specific drug target candidates - Nature Microbiology
This study presents a pooled CRISPRi screening approach in Candida albicans to investigate essential genes at scale, revealing environment- and strain-dependent gene sensitivities and conserved vulner...
links.springernature.com
We did a thing: Scientists find a new way coronaviruses can get into human cells www.cam.ac.uk/research/new...
Scientists find a new way coronaviruses can get into human cells
An international team of researchers has identified an East African bat coronavirus capable of entering human cells.
cam.ac.uk
Fantastic paper by Dalan Bailey and Stephen Graham’s labs and colleagues in Kenya. Bat alphaCoVs don’t use any of the previously known receptors, but some in Kenya can use human CEACAM6, a lung expressed adhesion factor, to enter human cells. www.nature.com/articles/s41...
Heart-nosed bat alphacoronaviruses use human CEACAM6 to enter cells - Nature
Human CEACAM6, which is widely expressed in the lung, is identified as a receptor used by the spike proteins of Cardioderma cor (heart-nosed bat) alphacoronaviruses to enter cells.
nature.com
I am extremely happy to share that the final paper from my PhD in @litinice.bsky.social 's team at @ircan.bsky.social (Université Cote d'Azur, @cnrscotedazur.bsky.social) is now out in @natcomms.nature.com !!! 😁😁😁 👇 www.nature.com/articles/s41...
The adaptive molecular landscape of reprogrammed telomeric sequences - Nature Communications
The molecular mechanisms allowing organisms to adapt to new telomeric sequences remain poorly understood. Here, the authors engineer multiple yeast lines with human-like telomeric repeats to unveil th...
nature.com
#DasGewichtDerWelt Unsere KINOTOUR steht. In fast 30 Städten gibt es Filmgespräche mit Regisseur Florian Heinzen-Ziob, Glaziologin Maria Hörhold, Biologin Nana-Maria Grüning und Chemiker Sebastian Seiffert. Mehr Details sowie Links zum Ticketing gibt es hier: mindjazz-pictures.de/filme/das-ge...
Es ist eine große Schlappe für die Strafverfolgungsbehörden, die versuchen, die ehemalige Klimagruppe Letzte Generation nach Paragraf 129 zu einer kriminellen Vereinigung erklären zu lassen. 👉 taz.de/!6168839/
Proud of our new paper just out in the @genetics-gsa.bsky.social's #GENETICS journal academic.oup.com/genetics/adv...!
Genetic and environmental determinants of multicellular-like phenotypes in fission yeast
Abstract. Multicellular fungi have repeatedly given rise to primarily unicellular yeast species. Some of these, including the fission yeast Schizosaccharom
academic.oup.com
Welche Verantwortung haben Wissenschaftler:innen in Zeiten der Klimakrise? Sollten wir uns in den Elfenbeinturm zurückziehen oder die Gesellschaft mit unseren Erkenntnissen konfrontieren? Neuer Trailer zum Dokumentarfilm "Das Gewicht der Welt" (Kinostart 7.5.2026) 👇
Pls re-post: My department @oxfordbiochemistry.bsky.social are recruiting for several new faculty positions (links below). Broad search in molecular biology/biochemistry, across prokaryotes and eukaryotes. Interested in understanding life at the molecular level, this job might be for you! 1/n
Job Details
my.corehr.com
We have started a project trying to predic the interactions/structures of all yeast protein pairs using an AlphaFold pooling approach. We are making the current dataset open and we welcome collaborations. www.evocellnet.com/2026/03/mapp...
Mapping the yeast atructural interactome with AlphaFold3: an open call for collaboration
We are excited to announce the early-stage release of our S. cerevisiae structural interactome mapping project. Using AlphaFold3 (AF3), w...
evocellnet.com
So honored to share that I've been awarded a scholarship by the Christiane-Nüsslein-Volhard foundation 😀🎉 - supporting #WomenInScience who are raising kids! The invisible load of combining family and research career is real and rarely so directly acknowledged. Thank you, CNV foundation! 🦠💻👩🏼🔬🧒🏼🧒🏼👶🏼
Funded PhD studentship (UK students only) available on clinical proteomics, application deadline 22nd March for Oct 2026 start! This project seeks to understand treatment responses to exacerbations experienced by people with CF using proteomics. www.findaphd.com/phds/project...
Proteomic Signatures of Treatment Response During Pulmonary Exacerbations in Cystic Fibrosis at University of Liverpool on FindAPhD.com
PhD Project - Proteomic Signatures of Treatment Response During Pulmonary Exacerbations in Cystic Fibrosis at University of Liverpool, listed on FindAPhD.com
findaphd.com
I have a 3-year postdoc position available at University of Manchester for a mass spec expert in proteomics. The person will be involved in exciting projects in single cell proteomics, drug discovery and innate immunity - on timsTOF Ultra AIP & HF & Astral Zoom. www.jobs.ac.uk/job/DQJ093/r...
Home - Trost Lab
trostlab.org
🚨4-year fully funded PhD in the lab of @magicmicrobe.bsky.social (& collaborating with me!): How does iron availability shape the ability of pathogens to invade the gut microbiome? Apply by Jan 26th Advert: research.reading.ac.uk/foodbiosyste... How to apply: research.reading.ac.uk/foodbiosyste...
research.reading.ac.uk
This work is the first paper issued from a fantastic collaboration with @litinice.bsky.social , Bertrand Llorente and Marco Cosentino Lagomarsino aiming at revisiting the yeast life cycle onlinelibrary.wiley.com/doi/10.1002/.... Hopefully more is coming soon :-)
The budding yeast life cycle: More complex than anticipated?
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onlinelibrary.wiley.com
Last work of the lab showing that Repeated losses of self-fertility shaped heterozygosity and polyploidy in yeast evolution | PNAS www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
pnas.org
The climate crisis is accelerating - 2025 looks set to become UK’s hottest year on record. Good to see focus on importance of resilience on #r4today- pls take a moment to sign petition calling on Govt to introduce a fully funded national climate adaptation plan petition.parliament.uk/petitions/73...
Petition: Fund a National Climate Resilience Plan: protect communities from climate impact
From floods to extreme temperatures, climate impacts risk damaging homes, health, businesses, services, and the economy. We want Government to prioritise adaptation; fund a new Resilience Plan that wo...
petition.parliament.uk
I’m excited to share a new postdoctoral opportunity in my lab at Stanford to study the consequences of gene dosage alterations in iPS cells. Check out the posting below and shoot me an email if you’re interested -
Just published in JBC @asbmbjournals.bsky.social - HSV-1 pUL21 teaches us that the universe of protein phosphatase 1 (PP1) binders may be much larger than previously recognised: www.jbc.org/article/S002... Bluetorial at bsky.app/profile/atom... Viruses - is there anything they can't do? 🦠💪
Alphaherpesvirus pUL21 homologues use non-canonical sequences to compete with cellular adaptors for protein phosphatase 1 binding
Protein phosphatase 1 (PP1) is a key regulator of cellular phosphorylation and its activity is regulated via binding to cellular regulatory proteins via conserved short linear motifs (SLiMs). The herp...
jbc.org
Stephen Graham's Lab@atomicvirology.bsky.social · last yr.How does #herpes hijack a human phosphatase to promote virus replication? We have a new @biorxivpreprint.bsky.social preprint showing how #HSV and #VZV use a novel motif to compete with canonical cellular #PP1 adaptors. www.biorxiv.org/content/10.1... 🧵👇
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions. Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research. Apply now ➡️ www.crick.ac.uk/careers-stud...
What a great conference #Candida2025 was! So happy about having met so many friendly new faces, and great to have had so much interest in how we do high throughput #proteomics with natural C albicans isolates. Looking forward to fun new collaborations! Thank you @microbiologysociety.org ❤️
a cat sitting on a couch using a laptop with the word research written on the screen
ALT: a cat sitting on a couch using a laptop with the word research written on the screen
media.tenor.com
New preprint from the lab: we show that the ability to switch mating type was lost at least 13 times independently in the evolution of S. cerevisiae. At least 27% of isolates are heterothallic with a strong association with polyploidy and heterozygosity www.biorxiv.org/content/10.1...
Repeated losses of self-fertility shaped heterozygosity and polyploidy in yeast evolution
Evolutionary transitions in mating strategy have profound consequences for genetic variation and adaptation. In Saccharomyces cerevisiae, mating-type switching is a central feature of the life cycle t...
biorxiv.org
how (yeast) cells re-climb the fitness landscape when they are reprogrammed to a different telomere DNA sequences (human-like)? read the latest from @melaniadangiolo.bsky.social etal , with great help and insights from Eric Gilson, Jonas Warringer and @juliamuenzner.bsky.social (& Ralser lab)
Melania D'Angiolo@melaniadangiolo.bsky.social · last yr.Superhappy to share the last paper from my PhD in @litinice.bsky.social lab. We evolved yeasts with humanized telomeric repeats and discovered that they adapt through amplification of telomere-binding proteins and inactivation of the DNA damage response. www.biorxiv.org/content/10.1...
Superhappy to share the last paper from my PhD in @litinice.bsky.social lab. We evolved yeasts with humanized telomeric repeats and discovered that they adapt through amplification of telomere-binding proteins and inactivation of the DNA damage response. www.biorxiv.org/content/10.1...
The adaptive molecular landscape of reprogrammed telomeric sequences
Telomeric sequences vary across the tree of life and intimately co-evolve with telomere-binding protein complexes. However, the molecular mechanisms allowing organisms to adapt to new telomeric sequen...
biorxiv.org