Out in its final form! Congratulations @sejpaton.bsky.social @jolusolo.bsky.social Alice Cadoret @adelinec.bsky.social @luisa-binder.bsky.social Béatrice Daigle @laura-mb.bsky.social Laurence Dion-Albert @katarzynaadudek.bsky.social @manonlebel5.bsky.social 🥂🧠🤓 www.nature.com/articles/s41...

Environmental enrichment and physical exercise prevent stress-induced social avoidance and blood-brain barrier alterations via Fgf2 - Nature Communications

Chronic stress disrupts the brain vasculature and contributes to mood disorders, but mechanisms of resilience remain unclear. Here, the authors show that enriched environments increase astrocytic Fgf2...

nature.com

New paper alert!!...🤩 Led by @blogeman.bsky.social, we identify how cell type-specific hormonal responses in the hypothalamus tunes parenting behavior in males and females 🐭🧠🍼. Highlights in thread 👇 1/6 www.biorxiv.org/content/10.6...

Cell Type-Specific Hormonal Signaling Configures Hypothalamic Circuits for Parenting

Parenting behavior emerges from hormonally sensitive circuits, but how distinct circuit components are affected by, and contribute to, sex and state dependent changes in infant caregiving remains uncl...

biorxiv.org

📣#TellUsAboutYourResearch: Meet Dr. Jonathan VanRyzin @jwvanryzin.bsky.social, a postdoctoral fellow at the University of North Carolina! His research investigates how microglia and astrocytes sculpt neural circuits underlying motivated behavior. #MeetThePNIResearcher

😍😍😍

Kristen Montgomery@kristenmontgomery.bsky.social · 8mo ago

A favorite recent image of some busy microglia, lovingly named the Rat King (yellow CD68, pink Iba1, blue DAPI) for my first #FluorescenceFriday

A favorite recent image of some busy microglia, lovingly named the Rat King (yellow CD68, pink Iba1, blue DAPI) for my first #FluorescenceFriday

In @elife.bsky.social: Sex differences in BNST signaling and BNST CRF in fear processing doi.org/10.7554/eLif... Official version finally out. Thank you to reviewers, made it better!

Sex differences in BNST signaling and BNST CRF in fear processing

Critical differences in how the BNST responds to different types of fear across male and female mice.

doi.org

Join us for the next live webinar in the #PNIRS Presents Speaker Series: 🗣️ Dr. Laura Fonken from UT Austin 🪧 "Microglial rhythms contribute to sex-specific changes in behavior across the lifespan" 📆 Tues. Dec. 9th, 11:00am ET RSVP is FREE and you don't need to be a member! pnirs.org/pnirs-presents

Jumping spiders can recognise one another. This ability to learn, remember and represent images is quite surprising for such a tiny-brained animal! buff.ly/dCkwPr0

Very glad to share our newest paper published in Molecular Psychiatry: Investigating milk-derived extracellular vesicles as mediators of maternal stress and environmental intervention www.nature.com/articles/s41... fun collab w/ @jordanmarrocco.bsky.social. Please enjoy! #OpenAccess #MaternalHealth

Which human brain circuits are implicated in neurodevelopmental conditions? We bridged human genetics, spatial transcriptomics and neurodevelopment to discover the convergence of autism-associated genes in the developing human thalamus! www.biorxiv.org/content/10.1...

Check out our new review article from my lab: doi.org/10.1111/jnc....

Crosstalk Between Astrocytes and Inhibitory Neurons During Maturation: Emerging Mechanisms and Functional Implications

In this review, we discuss the development and maturation of inhibitory neurons and astrocytes and how early developmental activity in the brain might promote the interactions between these cell type...

doi.org

New preprint from the lab! We identified Vipr2-expressing BNST neurons as a distinct subpopulation of the oval nucleus that promotes feeding, is activated by food restriction, is non-overlapping with appetite-suppressing PKC delta neurons, and projects to PSTN & PVN hypothalamic feeding centers.

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 9mo ago

A Distinct Subpopulation of Extended Amygdala Neurons Drives Food Intake https://www.biorxiv.org/content/10.1101/2025.11.07.685941v1

Thrilled to share our new paper, out now in @natneuro.nature.com, uncovering how estradiol, the most potent estrogen, modulates reinforcement learning and reward prediction errors across biological levels. www.nature.com/articles/s41... #blueprint 1/7

Estrogen modulates reward prediction errors and reinforcement learning - Nature Neuroscience

Dopamine encoding of reward prediction errors naturally fluctuates over females’ reproductive cycles with estrogenic signaling due to reduced expression of dopamine reuptake proteins.

nature.com

Tools that track specific molecules in neurons have enabled researchers to probe previously unexplored aspects of neurobiology go.nature.com/4p2hyua

How genetically encoded sensors have lit up neuroscience

Tools that track specific molecules in neurons have enabled researchers to probe previously unexplored aspects of neurobiology — although important caveats remain.

go.nature.com

Can say that I've done this previously with my rats and it's 100% worth it to "hear" them giggle with a USV microphone 🤣

Joanna Bagniewska@joannabagniewska.com · 9mo ago

🐀Male and female rats like to be tickled differently - males prefer rougher play. 🤣How do we know? Rats produce ultrasonic giggles that can be monitored with a bat detector. 🧪Why is this relevant? To improve lab animal welfare. Ah, to tickle rats for a living...♥️ f1000research.com/articles/14-...

Check out our latest, online now at @sfnjournals.bsky.social www.jneurosci.org/content/earl...

Superior colliculus projections drive dopamine neuron activity and movement but not value

To navigate dynamic environments, animals must rapidly integrate sensory information and respond appropriately to gather rewards and avoid threats. It is well established that dopamine (DA) neurons in...

jneurosci.org

Finally it’s here! 🌟⬇️ www.nature.com/articles/s41... I’m sooo excited to share our latest article led by Steve Hill and Isabel Bravo-Ferrer 1- How does the vasculature communicate with astrocytes? 2- Is this communication dependent to what happens in the body. 3- Is it relevant to human diseases?

Science friends! I need your help. We have a Neurophotometrics FP system that we are having trouble integrating with behavioral tracking software for annotation purposes. For example, we want to align fluorescence with open/closed arm exploration in the EPM. Can you help us out??

Thrilled to share our new paper @cp-cell.bsky.social: “Microglia–astrocyte crosstalk regulates synapse remodeling via Wnt signaling.” This work demonstrates the necessity of glia–glia communication and coordination during synapse remodeling. 🔗 www.cell.com/cell/fulltex... Faust et al., Cell 2025

Prenatal stress induces transient developmental alterations in distinct GABAergic populations and leads to long-lasting behavioral abnormalities www.sciencedirect.com/science/arti...

Prenatal stress induces transient developmental alterations in distinct GABAergic populations and leads to long-lasting behavioral abnormalities

Prenatal stress (PNS) is a well-established risk factor for psychiatric disorders, yet the underlying neurobiological mechanisms remain unclear. Here,…

sciencedirect.com

Excited my PhD work in @brianmathur.bsky.social’s lab is now published and available!

Bertoglio lab (FMC/UFSC)@bertogliolab.bsky.social · 12mo ago

Serotonin and psilocybin activate 5-HT1B receptors to suppress cortical signaling through the claustrum doi.org/10.1038/s414...

If you have a "recently" (in the last 2 years) published paper with a preprint available, I’d love to hear from you! All neuroscience topics are welcome. 🙏🏼 Thank you!

Elena Blanco-Suárez@eblancosuarez.bsky.social · 12mo ago

I’m designing a course that uses preprints and their peer-reviewed, published versions to directly compare how manuscripts are originally conceived by authors and how the peer-review process shapes their final form.🎯My goal is to help students strengthen critical thinking and become fair reviewers.

I am SO EXCITED to share this one! The latest paper from the lab is online in @cp-cellreports.bsky.social. We show microglia prune NAc astrocyte processes during abstinence from cocaine-self ad which drives later drug seeking behavior. www.sciencedirect.com/science/arti...

Abstinence from cocaine self-administration promotes microglial pruning of astrocytes, which drives cocaine-seeking behavior

Rodent drug self-administration leads to a compromised ability of nucleus accumbens astrocytes to maintain glutamate homeostasis as well as to reducti…

sciencedirect.com

Incredibly grateful to be one of the 2025 BBRF Young Investigator Grant awardees! Thank you to @bbrfoundation.bsky.social and to my mentors for their support along the way!

Review now out in @npp-journal.bsky.social! Epigenetic regulation of brain development, plasticity, and response to early life stress rdcu.be/ezzYq

Epigenetic regulation of brain development, plasticity, and response to early-life stress

Neuropsychopharmacology - Epigenetic regulation of brain development, plasticity, and response to early-life stress

rdcu.be

#ThisWeekInNPP This study explored how prenatal & postnatal THC exposure affects 🧠 development & social behavior in 🐭, highlighting an impact on microglial phagocytosis in the developing amygdala in a sex-specific & timing-dependent manner ⏲️ / @jwvanryzin.bsky.social

Timing matters: modeling the effects of gestational cannabis exposure on social behavior and microglia in the developing amygdala - Neuropsychopharmacology

Neuropsychopharmacology - Timing matters: modeling the effects of gestational cannabis exposure on social behavior and microglia in the developing amygdala

nature.com

Excited to see our most recent project published in @npp-journal.bsky.social ! We show that the timing of THC exposure during development—prenatal vs. postnatal—leads to opposite effects on social behavior and microglial function in the amygdala. Timing matters! www.nature.com/articles/s41...

Timing matters: modeling the effects of gestational cannabis exposure on social behavior and microglia in the developing amygdala - Neuropsychopharmacology

Neuropsychopharmacology - Timing matters: modeling the effects of gestational cannabis exposure on social behavior and microglia in the developing amygdala

nature.com

Excited to announce our latest production! @jwvanryzin.bsky.social @aemarquardt.bsky.social @um-mind.bsky.social www.nature.com/articles/s41...

Timing matters: modeling the effects of gestational cannabis exposure on social behavior and microglia in the developing amygdala - Neuropsychopharmacology

Neuropsychopharmacology - Timing matters: modeling the effects of gestational cannabis exposure on social behavior and microglia in the developing amygdala

nature.com

Happy #FluorescenceFriday ! Sharing one of my favorite images I've taken of microglia phagocytosis featuring a neuron whose DAPI is all too happy to be eaten.

go.bsky.app/Lyzro3M !WELCOME! thought we might need a starter pack for all those coming over from the birdhouse - here's a GliaSky list. apologies for missing many of you - please do reply to get added and remember to repost so the newbies can find us!