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@kkranzer.bsky.social

Professor Infectious Disease Epidemiology LSHTM; Co-director THRU-Zim at BRTI, LMU; Own views

32 Posts653 Follower301 Folgt
Michael Marks@drmichaelmarks.bsky.social · 8mo ago

REMINDER 1) Last week to apply for a PhD studentship working on near patient syphilis diagnostics - deadline 5th December. 2) We also have an STI modelling PhD open for applications until mid January. If interested do get in touch.

Michael Marks@drmichaelmarks.bsky.social · 9mo ago

Two syphilis/STI related UK PhD Studentships with our group: Evaluating near-patient syphilis tests with @uclglobalhealth.bsky.social inyurl.com/aw9sapma deadline 5th Dec 2025 Mathematical models to understand partner notification tinyurl.com/2re7xasj deadline 14th Jan 2026 Please do share

A picture of the spirochete that causes Treponema pallidum
Carole Mitnick@cdmitpih.bsky.social · last yr.

We are $5 billion/year short of our needs in TB research. This curable, preventable disease can be eliminated with concerted, sustained attention. The current toddler- tantrum approach is, shall we say, less than helpful. #TBSky

Lisa MD@gardeninglisa.bsky.social · last yr.

Right? Speaking of TB, had to discuss starting meds for TB case this week. Options are 2 drugs, both 70+ yrs old with side effects and drug interactions issues. Research needs to be done.

Jane Falconer@falkie71.bsky.social · last yr.

I'm pleased to announce i've a new paper published. It's a review on dengue diagnosis I did the searches for. It's part of the @lshtm.bsky.social FIEBRE project www.lshtm.ac.uk/research/cen.... Available on the Lancet Microbe at www.sciencedirect.com/science/arti... #sysrev #dengue #diagnosis

Evaluating the performance of common reference laboratory tests for acute dengue diagnosis: a systematic review and meta-analysis of RT-PCR, NS1 ELISA, and IgM ELISA

Dengue fever is listed among the top ten global health threats by WHO. Prompt identification of dengue virus can guide clinical management and outbrea…

sciencedirect.com

@kkranzer.bsky.social · last yr.

Sepsis is one of the most frequent causes of death worldwide & yet in many LMICs we have no or low quality phenotypic diagnostics to guide our therapy. This is particularly problematic in the context of neonatal sepsis where ESBL Kleb pneumo is often implicated. @lshtmamrcentre.bsky.social

@kkranzer.bsky.social · last yr.

Molecular cartridge based diagnostics have been a game changer for TB diagnostics - why can we not do the same for blood cultures? Please see our newest publication in collaboration with FIND, Sally Mugabe Central Hospital, the NMRL & @thruzim.bsky.social PLOS: dx.plos.org/10.1371/jour...

@kkranzer.bsky.social · last yr.

Molecular cartridge based diagnostics have been a game changer for TB diagnostics - why can we not do the same for blood cultures? Please see our newest publication in collaboration with FIND, Sally Mugabe Central Hospital, the NMRL & @thruzim.bsky.social PLOS: dx.plos.org/10.1371/jour...

Rapid bacterial identification and resistance detection using a low complexity molecular diagnostic platform in Zimbabwe

Background Sepsis is a major cause of mortality in low-resource settings. Effective microbiological culture services are a bottleneck in diagnosis and surveillance. Aim We aimed to evaluate the perf...

dx.plos.org

PLOS Global Public Health@plosglobalpublichealth.org · last yr.

NEW research in PLOS Global Public Health from @emarambire.bsky.social & colleagues from @lshtm.bsky.social and @tropeninstitut.bsky.social : Prediction models for Mtb infection among adolescent and adult household contacts in high tuberculosis incidence settings journals.plos.org/globalpublic...

Prediction models for Mtb infection among adolescent and adult household contacts in high tuberculosis incidence settings

Tuberculosis household contacts are at high risk of developing tuberculosis. Tuberculosis preventive therapy (TPT) is highly effective, but implementation is hindered by limited accessibility of diagn...

journals.plos.org

@kkranzer.bsky.social · last yr.

Thank you for this important work! While we all know that the US funding cuts will have huge implications, seeing the high number of access TB deaths is shocking & saddening. @tb-lshtm.bsky.social @kchorton.bsky.social

Katherine Horton@kchorton.bsky.social · last yr.

New pre-print modelling impact of US funding cuts on HIV, #TB, MCH and family planning. We estimate impact of termination of US funding to NTPs via #USAID & The Global Fund may lead to 2.2 (1.5-2.9) million excess TB deaths between 2025 and 2040, reversing over a decade of progress. bit.ly/4lowp18

Line chart showing median number of TB deaths in 79 low- and middle-income countries from 2010 through 2040. A black line shows a decline from 1.25 million deaths in 2010 to just under 1 million deaths in 2024. A blue line shows the number of deaths staying constant through 2040 if 2024 funding and programmes are maintained. A red line shows the number of deaths increasing to 1.2 million in 2040 if US funding to national TB programmes is terminated.
@kkranzer.bsky.social · last yr.

@emarambire.bsky.social congratulation to not just publishing this paper but also to submitting your #PhD thesis today. I feel v privileged to have v been part of your journey for the last 5 years! Massive congrat! @lmumuenchen.bsky.social @thruzim.bsky.social

PLOS Global Public Health@plosglobalpublichealth.org · last yr.

NEW research in PLOS Global Public Health from @emarambire.bsky.social & colleagues from @lshtm.bsky.social and @tropeninstitut.bsky.social : Prediction models for Mtb infection among adolescent and adult household contacts in high tuberculosis incidence settings journals.plos.org/globalpublic...

Alberto Garcia-Basteiro@agbasteiro.bsky.social · last yr.

Changes in incarceration and #tuberculosis notifications from prisons during the #COVID-19 pandemic in Europe & the Americas: a time-series analysis of national surveillance data Lower than expected #TB notifications! due to missing diagnoses? Lower transmission? www.thelancet.com/journals/lan...

Changes in incarceration and tuberculosis notifications from prisons during the COVID-19 pandemic in Europe and the Americas: a time-series analysis of national surveillance data

Tuberculosis notifications in prisons from 47 countries in Europe and the Americas were lower than expected (at times >50% lower) during COVID-19 pandemic years, despite consistent incarceration level...

thelancet.com

Gabriele Pollara@gpollara.bsky.social · last yr.

If you can't afford to use a diagnostic test, then its relative performance characteristics become irrelevant. Important issue raised re blood cultures 👇 @lancetmicrobe.bsky.social #ClinMicro #IDSky #AMR www.thelancet.com/journals/lan...

The cost of blood cultures: a barrier to diagnosis in low-income and middle-income countries

The recent Editorial by The Lancet Microbe, titled Rethinking blood culture, highlights the blood culture bottle shortage in the USA and the overreliance on single manufacturers.1 The shortages of blo...

thelancet.com

@kkranzer.bsky.social · last yr.

Thank you @edctp3-cryptott.bsky.social for funding this transformative consortium which will support researcher in #Mozambique #Zambia and #Zimbabwe across different levels of their career.

THRU ZIM@thruzim.bsky.social · last yr.

We’re thrilled to launch the 𝗦𝗼𝘂𝘁𝗵𝗲𝗿𝗻 𝗔𝗳𝗿𝗶𝗰𝗮 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗖𝗮𝗽𝗮𝗰𝗶𝘁𝘆 𝗡𝗲𝘁𝘄𝗼𝗿𝗸 (𝗦𝗢𝗙𝗔𝗥) website – a hub dedicated to strengthening research capacity across Africa Visit: www.sofarafrica.org @kkranzer.bsky.social @lshtm.bsky.social @zambartresearch.bsky.social @tropeninstitut.bsky.social

Mahdad Noursadeghi@mnoursad.bsky.social · last yr.

We’re hiring! Looking for a laboratory post-doc fellow to help us disentangle protective and pathogenic T cells in TB, so we can stratify disease-risk after infection, and develop more effective vaccines. Interdisciplinary science in the heart of London. What's not to like? More here: bit.ly/4iIEiwu

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@kkranzer.bsky.social · last yr.

Qualitative researchers are active listening to people. Sometimes people talk about sad & painful experiences. Providing emotional support to researchers is really important. Thank you Nonhlanhla for your insightful presentation. @thruzim.bsky.social

THRU ZIM@thruzim.bsky.social · last yr.

2/3 Nonhlanhla's thought-provoking talk challenged conventional qualitative research approaches and highlighting the need to embed emotional support for researchers in study design.

Rachael Burke@rachaelburke.bsky.social · last yr.

A few months ago, I was honoured to receive the Stephen Lawn prize (with Ali Esmail). The Lancet wrote a profile of me, published today! www.thelancet.com/journals/lan.... I'm v looking forward to being at the Steve Lawn lecture on Thursday, by Dr Tereza Kasaeva. www.lshtm.ac.uk/newsevents/e...

Rachael Burke: integrating equitable HIV and TB research and care

“I think what I've really wanted to do since I was a teenager was work on HIV and TB, and conditions that affected people who were disproportionately poor and vulnerable. And research was a nice way i...

thelancet.com