Hello! We are a new @scienceinnovation.ec.europa.eu project building bacteria that only grow by making methanol-based chemicals instead of releasing CO2. 🌬️🦠 📈 Follow our journey and learn more at carboncare-project.eu Eight partners, six countries, one goal: Fermentation 2.0. #microsky 🧪

It was time for a new group photo, now with 12 people from 8 countries. 😊 🇳🇱 🇩🇪 🇨🇳 🇮🇹 🇬🇷 🇧🇬 🇸🇮 🇺🇸

Please share: we are looking for an experienced scientist to join the team of NeCEN, the Dutch facility for advanced cryo-electron microscopy here in Leiden. Detailed information about the position is available here: careers.universiteitleiden.nl/job/Cryo-EM-...

Please share: Open PhD position We are hiring a PhD student to work on the biocatalytic depolymerization of new biopolymers. The PhD candidate will be supervised by @larsjeuken.bsky.social at the Leiden Institute of Chemistry, with me as co-supervisor. careers.universiteitleiden.nl/job/PhD-Posi...

Methanol is an increasingly important single-carbon feedstock to facilitate the transition towards a circular bioeconomy. In our new paper, we engineered Methylobacterium extorquens to produce the polyketide phloroglucinol solely from methanol: www.sciencedirect.com/science/arti...

Establishing and optimizing phloroglucinol biosynthesis from methanol in Methylobacterium extorquens AM1 via strain engineering and medium optimization

Methanol serves as an increasingly important single-carbon feedstock that may help to facilitate the transition towards a circular bioeconomy. The Alp…

sciencedirect.com

Genetically enhanced bacteria can potentially become an effective tool for bioremediation. The state of the field is nicely summarized in a Spotlight article appearing in @nature.com, to which I was glad to contribute some comments. Check it out here: www.nature.com/articles/d41...

Are microbes the future of pollution clean-up?

Synthetic biologists are engineering bacteria to feast on oil, plastic and toxic chemicals.

nature.com

I am happy to share that a joint EIC Pathfinder Open project has been funded. The CarboNcare consortium will develop disruptive technology for the sustainable production of chemicals from methanol. cordis.europa.eu/project/id/1...

CARBON-EFFICIENT BIOPRODUCTION OF CHEMICALS FROM METHANOL | CarboNcare | Project | Fact Sheet | HORIZON | CORDIS | European Commission

A major challenge in carbon-based bioproduction is achieving high-yield conversion of carbon feedstocks—such as methanol—into target compounds, while avoiding carbon losses to biomass or CO2 emissions...

cordis.europa.eu

Please share: I am hiring a postdoc that will work on enzyme characterization and engineering in the frame of a recently granted EU consortium project. Read all details here and apply until February 5: careers.universiteitleiden.nl/job/Postdoct...

Our team met at Córdoba to kick off our @horizoneu.bsky.social project last month! 🇪🇺 “It was a fantastic opportunity for everyone to dive into the plans for metabolic engineering of cyanobacteria.” Partners sharer their experience and roles in the C5 project. Thank you for hosting us @uco.es!

Last week, I attended the kick-off meeting for our EU-funded C5 project in Cordoba, Spain. It was great to discuss our plans for the metabolic engineering of Cyanobacteria in detail with all partners, and I really enjoyed the visit to sunny Andalusia.

GlcNAc build-up acts as a key metabolic signal in #Streptomyces, but how does it triggers developmental responses? @gillesvanwezel.bsky.social &co show that the enzyme NagS dehydrates GlcNAc-6P into a reactive intermediate, triggering a toxicity-based checkpoint @plosbiology.org 🧪 plos.io/44pE08I

Recently, I had the pleasure of presenting our work at the first CO2FIX conference in Tianjin, China. It was great to see how seriously this research area is taken in China and how breakthroughs in research are rapidly moving towards large-scale applications in biotechnology.

Please share: I am hiring a postdoc that will work on enzyme characterization and engineering in the frame of the EU consortium project C5. Read all details here and apply until August 10: www.universiteitleiden.nl/en/vacancies...

Postdoctoral researcher on enzyme characterization and enzyme engineering

The Faculty of Science / the Institute for Biology is looking for a: Postdoctoral researcher on enzyme characterization and enzyme engineering Vacancy number: 15834   Project description We are hiring...

universiteitleiden.nl

Great collaboration with @lennartschada.bsky.social on an #enzyme converting the #plastic component ethylene glycol and to a feedstock chemical for microbes. Offering new ways to use plastic biotechnologically. 🧪

Lennart Schada von Borzyskowski@lennartschada.bsky.social · last yr.

Ethylene glycol is widely used as monomer of the plastic PET. It is therefore highly relevant as sustainable feedstock for microbial biotechnology. In our new paper in @natcomms.nature.com, we characterize efficient enzymes for ethylene glycol oxidation: www.nature.com/articles/s41...

Ecogenomics and functional biogeography of the Roseobacter group in the global oceans based on 653 MAGs and SAGs www.biorxiv.org/content/10.1... #jcampubs 🌊

Ethylene glycol is widely used as monomer of the plastic PET. It is therefore highly relevant as sustainable feedstock for microbial biotechnology. In our new paper in @natcomms.nature.com, we characterize efficient enzymes for ethylene glycol oxidation: www.nature.com/articles/s41...

I am happy to share that a joint EIC Pathfinder Challenges project has been funded. The C5 consortium will develop disruptive technology for the sustainable production of isoprene from carbon dioxide. Stay tuned for more updates and open positions. cordis.europa.eu/project/id/1...

Clever Combination of Synthetic Compartmentalization, Carbon Fixation and Compound Biomanufacturing | C5 | Projekt | Fact Sheet | HORIZON | CORDIS | European Commission

The C5 Pathfinder project aims to revolutionize the production of bio-based chemicals by leveraging synthetic compartmentalization and metabolic engineering within photosynthetic cyanobacterial system...

cordis.europa.eu

1/3 Although the issue of releasing GMOs for env bioremediation has been virtually absent of the mainstream scientific literature in Europe/US for >20 yrs, the topic has continued strong in Asia—alas in less fancy/visible journals. Time to revisit the subject in view of new global challenges 💪🏻!

Genetically enhanced bacteria can potentially become an effective tool for bioremediation in the future. Recently, an exciting breakthrough study about an engineered strain of the marine bacterium Vibrio natriegens was published in @nature.com: www.nature.com/articles/s41...

Bioremediation of complex organic pollutants by engineered Vibrio natriegens - Nature

A synthetic biology approach was used to engineer Vibrio natriegens into a strain capable of bioremediating complex organic pollutants in saline wastewater and soils, thereby addressing notable threat...

nature.com

@dirktischler.bsky.social is opening the @vaam-microbes.bsky.social conference 2025 at @ruhr-uni-bochum.de. Looking forward to three days of presentations, posters, and networking!

Only one week left to apply for this exciting PhD position, supervised by @gillesvanwezel.bsky.social and me! Please apply if you are interested in microbial biochemistry and have a solid background in enzymes, metabolic pathways, and bacterial genetics. www.universiteitleiden.nl/en/vacancies...

PhD aminosugar metabolism

The Faculty of Science / the Institute for Biology is looking for a :PhD Candidate , Aminosugar metabolism and control of growth and development in bacteriaVacancy number: 15487 PhD project descriptio...

universiteitleiden.nl

NEW: 2024 has just been confirmed as the warmest year on record, and the first to breach the 1.5C threshold. We used a ridgeline (Joy Division inspired) chart to visualise daily temperature anomalies since 1940. 2024 clearly stands out with 100% of its days above 1.3C and 75% above 1.5C.

Here's the Chancellor candidate of the German Greens, Robert Habeck, stating what everyone needs to know. Namely that a strong EU is the best counterweight to authoritarians like Musk and Trump. Which is why they support those parties that want to weaken the EU. [with English subtitles]

Synbio across environmental scales! By @ricardsole.bsky.social et al. doi.org/10.1021/acss...

Synthetic Ecosystems: From the Test Tube to the Biosphere

The study of ecosystems, both natural and artificial, has historically been mediated by population dynamics theories. In this framework, quantifying population numbers and related variables (associate...

doi.org

Not all Bradyrhizobium fix N2! In fact, most that live in soil probably don’t. We isolated a bunch from Arizona soils and found none had N-fixing or nodulation genes. We report their genomes and phylogeny here in an accepted paper at access microbiology! www.microbiologyresearch.org/content/jour...

High-quality PacBio draft genome sequences of 17 free-living Bradyrhizobium and four related Nitrobacteraceae strains isolated from arid soils in the Santa Catalina Mountains of Southern Arizona.

Non-symbiotic Bradyrhizobium are among the most abundant and ubiquitous microbes in bulk soils globally. Despite this, most available genomic resources for Bradyrhizobium are derived from plant-associ...

microbiologyresearch.org

Would you like to see @biorxivpreprint.bsky.social add a share to blue sky button?! I know I would! Share this post to let @richardsever.bsky.social @erictopol.bsky.social and others at bioarxiv know!

Which one are you? Among scientists are collectors, classifiers, and compulsive tidiers-up; many are detectives by temperament and many are explorers; some are artists and others artisans. There are poet-scientists and philosopher-scientists and even a few mystics. –Peter Medawar

The denitrification ability and #nitrogen metabolism pathway of aerobic #denitrifier Marinobacter alkaliphilus SBY-1 under low C/N ratios doi.org/10.1016/j.sc...

Sign of the times, no more bluebird on the biorxiv engagement tab..

🌐 We just joined Bluesky! SEVA is a free, open-access plasmid repository and an international standard supporting the synthetic biology community. Catch us here! #SynBio ⬇️ seva-plasmids.com

Home - SEVA plasmids - Standard European Vector Architecture

Standard European Vector Architecture 4.0 Welcome to the CNB-hosted database and material repository of standard and modular plasmid vectors for (de/re) constructing complex bacterial phenotypes ...

seva-plasmids.com