👏 J. Bigot & V. Balloy @CRSA-paris.bsky.social @sorbonne-universite.fr @hopital-stantoine.bsky.social, R. Legendre & C. Chica @Pasteur.fr + team 🫁 New insights into innate immune memory in lung epithelium #Flagellin 🦠 🙏 @vaincrelamuco.bsky.social & Fondation Air Liquide for support 🔬📄 👉 rdcu.be/eHY

The epigenomic landscape of bronchial epithelial cells reveals the establishment of trained immunity

Genes & Immunity - The epigenomic landscape of bronchial epithelial cells reveals the establishment of trained immunity

rdcu.be

Our last study about #aspergillus ABPA in #cysticfibrosis: Case-control study from the French registry academic.oup.com/mmy/article/... @crsa-paris.bsky.social @inserm.fr @fac-sante-sorbonne.bsky.social thanks @vaincrelamuco.bsky.social for funding 🙏

Allergic bronchopulmonary aspergillosis in cystic fibrosis: Case-control study from the French registry

Abstract. Allergic bronchopulmonary aspergillosis (ABPA) is a significant complication in people with cystic fibrosis (pwCF), driven by hypersensitivity to

academic.oup.com

Our proposed #coverart for a new study in @cp-iscience.bsky.social, from the labs of @loicguillot.bsky.social ky.social and @olivierterrier.bsky.social 🧪 📖 Full paper: lnkd.in/dSfrd8Z5 #biosky #medsky #lunghealth #COVID #Cysticfibrosis #chronicobstructivepulmonarydisease #sciart #scicomm

A previously unknown immunological function of the proteasome is its ability to release bactericidal compounds. This discovery presents a potential paradigm shift in antimicrobial therapy. It may contribute to addressing the global challenge of #AMR. www.nature.com/articles/s41...

Cell-autonomous innate immunity by proteasome-derived defence peptides - Nature

Proteasomal degradation of cellular proteins generate defence peptides constitutively and in response to bacterial infection. Such peptides might provide a source of natural antibiotics that...

nature.com

STAND UP FOR SCIENCE SPEAKER ANNOUNCEMENT! ☀️ Dr. Francis Collins will be speaking at Stand Up for Science in D.C. on March 7th! More speaker announcements coming soon, stay tuned! 👀☀️

Glad to share our work about SARS-COV-2 epithelial response according to pathological origin #CF #COPD with @olivierterrier.bsky.social Simon Rousseau @mcgill.ca & co! Grateful for the support from @sorbonne-universite.fr & Air Liquide foundation. @cnrs.fr @inserm.fr www.cell.com/iscience/ful...

Divergent responses to SARS-CoV-2 infection in bronchial epithelium with pre-existing respiratory diseases

Pre-existing respiratory diseases may influence coronavirus disease (COVID-19) susceptibility and severity. However, the molecular mechanisms underlying the airway epithelial response to severe acute ...

cell.com

Great to share our last collaborative work on trained immunity in bronchial cells. Bravo Jeanne Bigot @crsa-paris.bsky.social @sorbonne-universite.fr Rachel Legendre @pasteur.fr 🧪

bioRxivpreprint@biorxivpreprint.bsky.social · 2y ago

The epigenomic landscape of bronchial epithelial cells reveals the establishment of trained immunity https://www.biorxiv.org/content/10.1101/2025.02.03.636250v1

New online! Fungal biofilms in human health and disease

Fungal biofilms in human health and disease

Nature Reviews Microbiology, Published online: 05 February 2025; doi:10.1038/s41579-025-01147-0Fungal biofilms encompass a wide range of diseases with increasing clinical impact. In this Review, Ramage et al. discuss the clinical importance of fungal…

nature.com

Le CRSA change de tête: Félicitations à @loicguillot.bsky.social et Xavier Houard, nos nouveaux directeurs !

Widespread use of azole fungicides in agriculture may reduce the effectiveness of antifungal treatments for patients with aspergillosis. EMA highlights that nearly all 120,000 tonnes of azoles sold in the EU were used as pesticides, potentially contributing to #AMR www.ema.europa.eu/en/news/one-...

One Health: EU agencies unite to tackle azole fungicide resistance in Aspergillus fungi | European Medicines Agency (EMA)

The extensive use of azole fungicides (azoles), particularly in some agricultural and horticultural practices, can increase the risk of Aspergillus fungi developing resistance to essential antifungal ...

ema.europa.eu

Job alert! post-doctoral position on #macrophages biology to study the role of a post-translational modification in inflammation and ROS production with Tarik Issad's team @institutcochin.bsky.social in #Paris! Please apply on the @cnrs.bsky.social website: emploi.cnrs.fr/Offres/CDD/U...

#MedSky🧪 #IDsky #publichealth @thelancet.bsky.social Multidrug resistant Gram-ve bacterial infections cause significant morbidity & mortality globally. A new diagnostic & antibiotic Tx provide hope that we can better address this important #globalhealth issue. www.sciencedirect.com/science/arti...

🙏 to @niaidnews.bsky.social, first author @pauljbaker.bsky.social and my amazing lab team, our collaborators @kerryhilligan.bsky.social @danbarberphd.bsky.social 🙏to editor extraordinaire @hannah-isles.bsky.social and the reviewers who guided us along the way 9/9 www.science.org/doi/10.1126/...

The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication

Recent or ongoing respiratory inflammation in the lung regulates antiviral immune responses to SARS-CoV-2.

science.org

Harnessing neutrophils to enhance efficacy of host-directed therapy in pneumococcal pneumonia: www.mucosalimmunology.org/article/S193...

Does calorie labeling change food/energy consumption? Not in this new open-access report www.nature.com/articles/s41... @naturehumbehav.bsky.social

Evaluating the association between the introduction of mandatory calorie labelling and energy consumed using observational data from the out-of-home food sector in England - Nature Human Behaviour

The introduction of mandatory calorie labelling in out-of-home food outlets in England was not associated with a reduction in calories purchased or consumed. There was a post-policy increase in self-r...

nature.com

The strain on scientific publishing: we set out to characterise the remarkable growth of the scientific literature in the last few years, in spite of declining growth in total scientists. What is going on? direct.mit.edu/qss/article/... A 🧵 1/n #AcademicSky #PhDchat #ScientificPublishing #SciPub

🆕 Few thoughts we wanted to share with the community to look at 🍄 #aspergillosis diagnosis from a different perspective when we are still struggling on the topic. w/ @simonfeys.bsky.social @agocarvalho.bsky.social & cie Actively working on more answers. Stay tuned. 👉 doi.org/10.1016/j.cm...

Airway macrophage glycolysis controls lung homeostasis and responses to aeroallergen: www.mucosalimmunology.org/article/S193...

Do you know an experienced immunologist who is interested in studying human #immune development with next-generation methods? My lab is #hiring! Great pay, job stability, and a great place to work! Please share widely talent.stjude.org/careers/jobs...

St. Jude Is Hiring | Join Our Mission | St. Jude Careers

Explore job opportunities at St. Jude Children’s Research Hospital. Career opportunities exist in the areas of science, clinical care, operations, and more!

talent.stjude.org

🦠🧬🧫 Reminder that mBio publishes review articles and perspectives. If you have an idea in any area of microbiology or infection immunology, message me. No publication charge. Support Amer Soc Micro rather than a for-profit publisher! 📑💰 journals.asm.org/journal/mbio...

mBio Formatting Information

Overview of types of content published in mBio

journals.asm.org