Nineteen St. Jude scientists have been named to the 2025 Highly Cited Researchers list, the most from St. Jude since the list began. This distinction identifies those whose publications rank in the top 1% for citations, indicating broad influence. ow.ly/HKIk50XrffV

Super excited to present some of our newest work at @iuis-online.bsky.social #IUIS2025 in Vienna! Definitely the largest hall I’ve ever presented in.

The JCCLab is representing at #AAI2025!

Just saw a talk by Andrew Pask at #AGBT25 #AGBTGM on marsupial genomics, evolution, and gene editing for conservation. Completely mind blowing work. Taking both genetic editing and conservation work into a new frontier.

David Altshuler from Vertex kicking things off at #AGBT25 with an amazing talk but also an inspiring thought: “I hope that ‘hope’ is something that all of the work presented here can help create.” NIH-funded research is ultimately creating hope for the future, and we can’t forget that.

The JCC Lab is #hiring experienced bench scientists for work on human immunology and assay development! These are long term, stable positions not subject to the ebb and flow of federal funding. talent.stjude.org/careers/jobs...

St. Jude Is Hiring | Join Our Mission | St. Jude Careers

Explore job opportunities at St. Jude Children’s Research Hospital. Career opportunities exist in the areas of science, clinical care, operations, and more!

talent.stjude.org

I have collected Christmas ornaments for years, but two of my close collaborators just gifted me my first JCC Lab ornament! They said it’s a rocket because “the lab is taking off”. Thanks so much @asya-minervina.bsky.social and Misha!

Had a very productive and eventful time at @niaidnews.bsky.social for the annual meeting on the impact of initial influenza exposure on infant immunity. #immunology #development @eksliger.bsky.social @pgtimmune.bsky.social

Great interview of Sydney Brenner. One of my favorite stories of Crick and Brenner is their reaction to being scooped by Marshall Nirenberg in deciphering the genetic code. They were thrilled 🧪

The Thrill of Defeat

What Francis Crick and Sydney Brenner taught me about being scooped.

nautil.us

Matthew Cobb@matthewcobb.bsky.social · 2y ago

Given the love for Sydney Brenner whenever I post stuff about him, here’s a link to a BBC World Service programme I made about him, which included a visit to interview him in Singapore.

Excited to share this paper from my post-doc at @niaidnews.bsky.social out now in Science Immunology! We show that recent or ongoing 🫁 infections or other pulmonary environmental exposures at the time of infection with SARSCoV2 can vastly influence early replication of the virus in mice.

The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication

Recent or ongoing respiratory inflammation in the lung regulates antiviral immune responses to SARS-CoV-2.

science.org

Super cool work with wide-ranging implications!

Carolyn Bertozzi@carolynbertozzi.bskyverified.social · 2y ago

Amazing new work from the lab of @aliceyting.bsky.social @stanfordmedicine.bsky.social @stanfordbiosci.bsky.social, engineered GPCRs for ligand-activated cell responses www.nature.com/articles/s41...

very impressed by so many of India’s doctors and scientists stepping up to organize, innovate, and strategically confront the challenge of AMR that threatens their populous country and the world beyond 🇮🇳 🧫 🦠 💊 🇮🇳 www.bbc.com/news/article...

India's 'blockbuster' drugs to combat antibiotic-resistant superbugs

A number of promising new drugs from India show potential to fight antibiotic-resistant bacteria.

bbc.com

Great visit with an amazing talk and lovely dinner with @cobey.bsky.social today! And great company from @pgtimmune.bsky.social @rajerer.bsky.social ! Brilliant!

Affinity maturation of antibody responses is mediated by differential plasma cell proliferation doi.org/10.1101/2024...

Affinity maturation of antibody responses is mediated by differential plasma cell proliferation

Increased antibody affinity over time after vaccination, known as affinity maturation, is a prototypical feature of immune responses. Recent studies have shown that a diverse collection of B cells, pr...

doi.org

We could go on about how we welcome publishers, we don't demote links, we encourage independent developers to build apps and extensions on top of Bluesky's network.... but instead, we'll show you. All thanks to the incredible community here! 🦋

The Engagement Is Better on Bluesky - Bluesky

Bluesky is the lobby to the open web. Find and build your community here.

bsky.social

How does antiviral #immunity against #influenza evolve across human lifespan? 👶➡️👧➡️👱➡️👵 Our study in Nature Immunology investigates the difference in CD8 T cell response across human lifespan - a🧵⬇️ go.unimelb.edu.au/627s Katherine Kedzierska, Fabio Luciani, The Doherty Institute

A panoramic view of cell population dynamics in mammalian aging www.science.org/doi/10.1126/...

A panoramic view of cell population dynamics in mammalian aging

To elucidate aging-associated cellular population dynamics, we present PanSci, a single-cell transcriptome atlas profiling over 20 million cells from 623 mouse tissues across different life stages, se...

science.org

Design of high specificity binders for peptide-MHC-I complexes https://www.biorxiv.org/content/10.1101/2024.11.28.625793v1

Design of high specificity binders for peptide-MHC-I complexes https://www.biorxiv.org/content/10.1101/2024.11.28.625793v1

Class I MHC molecules present peptides derived from intracellular antigens on the cell surface for i

biorxiv.org

New publication by @aelewaut.bsky.social & @guillemxtivill.bsky.social from @obenaufa.bsky.social lab about cancer-mediated immune evasion – very interesting! #HemeSky #OncoSky www.nature.com/articles/s41...

Cancer cells impair monocyte-mediated T cell stimulation to evade immunity - Nature

Inflammatory monocytes are identified as important players in T cell restimulation in the tumour microenvironment.

nature.com

Hi all! I've created a started pack for academic professional development. Looking to build a community of folks supporting researchers, scholars, and educators (broadly defined) by sharing skills, tools, and resources. Please share and reply to nominate yourself or others! go.bsky.app/vGDioH

Talking of Bier, @orthopodreg.bsky.social the story of how he developed spinal anaesthesia is pretty wild A story of cocaine, cigars, and German army helmets. #AnSky #MedSky #HistoryMedSky

a baby rhino is playing with snow in a zoo enclosure .

Alt: a baby rhino is playing with snow in a zoo enclosure .

media.tenor.com

Hi everyone! To start on 🦋, we will share what we did during this crazy year!! 🤩🎉 To start, our work on the receptor of #CCHFV 🦠: www.nature.com/articles/s41... And related to that: our review on lipoproteins receptors used by viruses 🚪: www.jbc.org/article/S002...

How well do vaccines protect vs #LongCovid, a systematic review during the Omicron era? —about 20% reduced by primary series (vs no vaccination), and —another 20% reduction by boosters vs primary series www.medrxiv.org/content/10.1...

Who did I miss? Excited to get more SJ folks on the platform. go.bsky.app/Lv6kNiq

Do you know an experienced immunologist who is interested in studying human #immune development with next-generation methods? My lab is #hiring! Great pay, job stability, and a great place to work! Please share widely talent.stjude.org/careers/jobs...

St. Jude Is Hiring | Join Our Mission | St. Jude Careers

Explore job opportunities at St. Jude Children’s Research Hospital. Career opportunities exist in the areas of science, clinical care, operations, and more!

talent.stjude.org

Check out our updated database of 189 PhD fellowships and funding opportunities. For each fellowship, we provide a description, $ amount, deadline, link to funder and eligibility criteria (such as citizenship). Good luck! Download freely here: research.jhu.edu/rdt/funding-...

OK, #immunology Bluesky LFG! If, like me, you're trying to reconstruct the vibrant scientific network we had at the other place, these starter packs are a great start: go.bsky.app/2bqX3T7 go.bsky.app/PY5tCas go.bsky.app/FmERUoD go.bsky.app/AjNpW2h go.bsky.app/SinqoJU go.bsky.app/DmphBCT

Mentoring is the most important thing most of us can do. Here is a 🧵about what I've learned as a PI running an academic research lab. I hope some of the advice is helpful to those who are just starting their labs and to folks hitting the academic job market in search of an independent position 🧪 1/n

The remarkable drop in child mortality.

TCR repertoire dream: decoding immune status by sequencing TCRs. Problems: 1) Need paired TCRab 2) Interesting T cell clones are often VERY small. Our solution: TIRTL-seq 🐢Deep, quantitative, & affordable paired TCR repertoire sequencing🧵 https://www.biorxiv.org/content/10.1101/2024.09.16.613345v1