🧬 Excited to share our paper "Cilia SubQ," out now in Methods — semi-automated pipelines+ Cilia.AI for quantifying primary cilia & subdomains. Congrats to lead author Ellie Menzel! Paper: doi.org/10.1016/j.ymeth.2026.07.002 Cilia.AI, pipelines & tutorials: osf.io/hm38f In your lab? Reach out! #cilia
Halim Loukil
@loukillab.bsky.social
Principal Investigator | Sanford Research Institute & Assistant Professor, Pediatrics | University of South Dakota #cilia #rarediseases #centrioles #centrosome #brain #neuroscience #cilium #cilia http://Loukil-Lab.com
If you work on #PrimaryCilia 🔬 & spend too much time on manual image analysis, this might help! We built Cilia SubQ — automated cilia detection with analytical pipelines for basal body, transition zone, ciliary tip, and more (~8x faster ⏱️). Free on OSF 🦾 Congrats Ellie Menzel! 🎉 osf.io/hm38f
Last call for this job opening 🔊🔊 #Neuroscience #Cilia #Postdoc #neuro #SFN
The Loukil Lab has an opening for a Postdoctoral Researcher to study primary cilia in the brain and their roles in neurological disease. If you or someone you know might be interested, please share or reach out! 🧠✨ #Neuroscience #Cilia #Postdoc #neuro #SFN neurojobs.sfn.org/job/39311/po...
🥳 Our new paper on C2CD3 is out in @plosbiology.org With the labs of @cellarchlab.com , @chgenoud.bsky.social , and @stearnslab.bsky.social , we revealed the mammalian centriole Distal Ring architecture by combining #UExM and in situ #CryoET. Big congrats to @ebertiaux.bsky.social and all involved.
How does C2CD3 contribute to distal appendage formation in centrioles? @centriolelab.bsky.social show that C2CD3 acts as a central architectural organizer of the distal #centriole, bridging the luminal distal ring complex & peripheral appendage sites @plosbiology.org 🧪 plos.io/496XZuH
The Loukil Lab has an opening for a Postdoctoral Researcher to study primary cilia in the brain and their roles in neurological disease. If you or someone you know might be interested, please share or reach out! 🧠✨ #Neuroscience #Cilia #Postdoc #neuro #SFN neurojobs.sfn.org/job/39311/po...
Postdoctoral Position in Cilia-Neuroscience, Sanford Research Institute - Sioux Falls, South Dakota job with Sanford Research Institute | 39311
Join a team combining molecular neuroscience, mouse genetics, and advanced imaging to pioneer discoveries at the underexplored cilia–brain interface.
neurojobs.sfn.org
The Loukil Lab has an opening for a Postdoctoral Researcher to study primary cilia in the brain and their roles in neurological disease. If you or someone you know might be interested, please share or reach out! 🧠✨ #Neuroscience #Cilia #PostdocJobs www.indeed.com/m/viewjob?jk...
Neuroscience Postdoctoral Position – Loukil Lab, Sanford Research - Sioux Falls, SD 57104 - Indeed.com
Sanford Health
indeed.com
KIF13B controls ciliary protein content by promoting endocytic retrieval and suppressing release of large extracellular vesicles from cilia: Current Biology www.cell.com/current-biol...
KIF13B controls ciliary protein content by promoting endocytic retrieval and suppressing release of large extracellular vesicles from cilia
Rezi et al. show that kinesin-3 KIF13B regulates ciliary protein content by promoting endocytic retrieval and small extracellular vesicle (EV) release of ciliary proteins while suppressing their relea...
cell.com
Excited to see this work published online at @cp-cell.bsky.social today! www.cell.com/cell/fulltex...
A conserved mechanism for the retrieval of polyubiquitinated proteins from cilia
CFAP36, a conserved cilia-specific ubiquitin reader, partners with the ARL3 GTPase to enable the selective and directional retrieval of polyubiquitinated proteins from cilia, a process essential for m...
cell.com
How do cells keep their cilia “clean” and functional? Our new study uncovers a conserved mechanism for retrieving polyubiquitinated proteins from #cilia – a process essential for cellular signaling and health. #cellbiology #ciliopathy #ubiquitin #IFT 🧵👇 1/n
Thrilled to share our new paper on the in vivo BioID of neuronal cilia 🧬🌀 This is the first look at the signaling power of neuronal primary cilia in the mature mouse brain. Huge thanks to @sarahgoetz.bsky.social and amazing collaborators for making this possible! 🙏 www.jneurosci.org/content/45/3...
Very excited that our work describing hu.MAP3.0 is published in @molsystbiol.org. Here we use machine learning to integrate >25k mass spectrometry experiments to place ~70% of human proteins into 15k protein complexes. www.embopress.org/doi/full/10....
hu.MAP3.0: atlas of human protein complexes by integration of >25,000 proteomic experiments | Molecular Systems Biology
imageimagehu.MAP3.0 integrates mass spectrometry experiments to identify human protein complexes. Using this resource, this study characterizes covariation of complexes, identifies mutually exclusive ...
embopress.org
Please see a Perspective we wrote on our recent findings: onlinelibrary.wiley.com/doi/full/10....
TRiC Is a Structural Component of Mammalian Sperm Axonemes
The TRiC chaperonin is responsible for folding ~5%–10% of the proteome in eukaryotic cells. Our recent cryo-electron microscopy studies of axonemes from diverse mammalian cell types led to the surpri...
onlinelibrary.wiley.com
Mentoring is the most important thing most of us can do. Here is a 🧵about what I've learned as a PI running an academic research lab. I hope some of the advice is helpful to those who are just starting their labs and to folks hitting the academic job market in search of an independent position 🧪 1/n
🧬🧪Protein codes promote selective subcellular compartmentalization | Science www.science.org/doi/10.1126/... Henry Kilgore @itamarchinn.bsky.social @pgmikhael.bsky.social Ilan Mitnikov, et al. @aihealthmit.bsky.social @whiteheadinstitute.bsky.social @mitofficial.bsky.social
Protein codes promote selective subcellular compartmentalization
Cells have evolved mechanisms to distribute ~10 billion protein molecules to subcellular compartments where diverse proteins involved in shared functions must assemble. Here, we demonstrate that prote...
science.org
We got a Centrosome & Cilia starter pack 🙌 lots of space to add anyone interested!