Lotte B. Pedersen
@lottepedersen.bsky.social
Cell biologist interested in cilia research
Amazing to hold @lottepedersen.bsky.social & my @jcellsci.bsky.social Special Issue on #Cilia and #Flagella in all its glossy glory & muscle-engaging brain-boosting weight! So much fabulous content from the community! Fab cover @centriolelab.bsky.social 🥰🥰 journals.biologists.com/jcs/pages/ci...
📣 Seminar 📆 Thursday, January 22nd at 2 pm 📍 Institut Jacques Monod Next week, Seema Grewal ( @seemagrewal.bsky.social) , Executive Editor at Journal of Cell Science ( @jcellsci.bsky.social ) will present the seminar "The Future of Publishing" ➡️ buff.ly/j69lKP3
The EMBO Workshop "#Centrosomes: From fundamentals to diseases" in #Lausanne, Switzerland, 1–4 September 2026 will highlight the advances in the field of centrosome #research. Register now! Deadline: 1 June https://meetings.embo.org/event/26-centrosomes #EMBOCentrosomes #EMBOevents #conference 🧪
We are back April 21 2026- volunteer or nominate yourself or someone with hot cilia and centrosome science to speak by dropping me an email or use the google doc forms.gle/9QoSvkmQ3gZL...! /FIN
BSCB GenSoc UK Cilia Network e-symposium series talk
Sign-up to be on the rota of future speakers for the 2025 series!
forms.gle
From limitless primary basal cells for #PCD therapies, to the TOGORAM1 complex, cytoskeleton & ciliopathies, to #PrimaryCilia diversity in brain #microvasculature, to #ExtrasynapticSignaling at neuronal cilia by in situ proteomics, to an epigenetic 'eraser' controlling #cilia stability... 🔥 /fin
What a great start for 2026 for the EVICAT team!!! Everything you need to know about extracellular vesicles' recipient cells and how to harness these pathways for therapeutic purposes Thanks to all co-authors! bit.ly/3N9InyW
Biology and therapeutic potential of extracellular vesicle targeting and uptake - Nature Reviews Molecular Cell Biology
Extracellular vesicles are released from almost all cell types and mediate intercellular communication by delivering proteins, nucleic acids and lipids. This Review examines extracellular vesicle upta...
bit.ly
🌍 Cilia2027 | Mar 8–12, 2027 | 📍 Stresa, Lake Maggiore, Italy Join the global cilia community for science, collaboration & discovery (+ fun!!). #Cilia2027 #CiliaBiology
CDKL5 Deficiency Disorder (CDD) leads to seizures & intellectual disability. This study shows that #Chlamydomonas CDKL5 kinase is activated by the LF2/CDK20 kinase; CDKL5 in turn regulates #intraflagellar transport via protein abundance & phosphorylation #cilia @plosbiology.org 🧪 plos.io/45490eP
Very grateful to @carlsbergfondet.dk for supporting our Research Infrastructure application to purchase a new NTA for studying #cilia and #extracellular #vesicles 🙏😀 bsky.app/profile/carl...
Carlsbergfondet@carlsbergfondet.dk · 8mo agoFra politologi til arkæologi. Fra astrofysik til marinbiologi og glaciologi. 159 forskere modtager i dag en bevilling fra Carlsbergfondet til vidt forskellige grundvidenskabelige initiativer. Se hvilke projekter, der har fået støtte 👉 bit.ly/4iK2fV2 #dkforsk
🥳 Our new paper on C2CD3 is out in @plosbiology.org With the labs of @cellarchlab.com , @chgenoud.bsky.social , and @stearnslab.bsky.social , we revealed the mammalian centriole Distal Ring architecture by combining #UExM and in situ #CryoET. Big congrats to @ebertiaux.bsky.social and all involved.
PLOS Biology@plosbiology.org · 8mo agoHow does C2CD3 contribute to distal appendage formation in centrioles? @centriolelab.bsky.social show that C2CD3 acts as a central architectural organizer of the distal #centriole, bridging the luminal distal ring complex & peripheral appendage sites @plosbiology.org 🧪 plos.io/496XZuH
Nice work indeed… among all the interesting findings, quite amazed to see that you can induce the formation of ciliary pockets just by the removal of Arp3! #cilia #ciliopathies #kidney
club CFC@club-cfc.bsky.social · 8mo agoVery interesting paper! Arp2/3-dependent regulation of ciliogenesis governs adaptive distal tubular epithelial cell states in kidney disease | Science Advances www.science.org/doi/10.1126/...
Dynein-2 prefers to bind the retrograde-targeted A-tubule in intraflagellar transport - likely because of its tyrosination, suggest cryo-ET data and MD simulations by @ichikawa-lab.bsky.social and coworkers www.embopress.org/doi/full/10....
We’re excited for the UK Cilia and Centrosome Network e-symposium this afternoon featuring the #JCSciliaSI! To discover more about the research in this issue, check out these JCS snapshots, video highlights from authors about their research: focalplane.biologists.com/2025/11/24/j...
JCS snapshots: the cilia and flagella edition - FocalPlane
JCS snapshots: the cilia and flagella edition - News
focalplane.biologists.com
And we’ll be back for four sessions in 2026- first 14/01/2026! Register: www.eventbrite.co.uk/e/bscb-genso... #UKCilia2025 /9
BSCB GenSoc UK Cilia and Centrosome Network e-Symposia Series
BSCB GenSoc UK Cilia and Centrosome Network e-Symposia Series
eventbrite.co.uk
In the meantime, try a deep dive into our JCS Special Issue on Cilia and Flagella to fully immerse yourself into some great research, fantastic insight and provocative opinions: journals.biologists.com/jcs/issue/13... /fin
Volume 138 Issue 20 | Journal of Cell Science | The Company of Biologists
Journal of Cell Science publishes cutting-edge science encompassing all aspects of cell biology. It is published by The Company of Biologists, a not-for-profit organisation.
journals.biologists.com
Thanks for the shoutout! @jcellsci.bsky.social :)
Journal of Cell Science@jcellsci.bsky.social · 9mo agoIn their Perspective article, Muyang Ren, Siham Jaleel, Stephen King & Girish Mali @dyneinassembly.bsky.social highlight the structural diversity of the axonemal dynein assembly factors & their emerging roles in the biology of motile cilia. #JCSciliaSI journals.biologists.com/jcs/article/...
It was a lot of fun to write this review on cilia proteimics with Bernhard Schermer @cilib.social.cologne.ap.brid.gy and Ronald Ropeman, and we are excited to see it published in the @jcellsci.bsky.social special issue on Cilia and Flagella: from basic Biology to Disease.
Bernhard Schermer@cilib.bsky.social · 9mo ago📣 Here it is — our overview on ciliary proteomics! Great discussions and writing with @mick-lab.bsky.social and Ronald Roepman 🙏🙏 Hope we didn’t miss anything important - apologies if we did! #cilia #ciliopathies #proteomics @theracilproject.bsky.social @for5547.bsky.social tinyurl.com/yc8ztn5v
Rudolfo Karl, Elvira Mass, Dagmar Wachten @wachtenlab.bsky.social and colleagues discover that renal tissue-resident macrophages promote cystogenesis in early polycystic kidney disease. #JCSciliaSI journals.biologists.com/jcs/article/...
Thrilled to share "in situ APEX activation" (iAPEX), a proximity labeling technology for subcellular #proteomics applied to primary #cilia. iAPEX uses an enzymatic cascade, in which a D-amino acid oxidase locally produces H2O2 to activate ascorbate peroxidase. www.nature.com/articles/s41...
An enzymatic cascade enables sensitive and specific proximity labeling proteomics in challenging biological systems - Nature Communications
Proximity labeling allows proteomic mapping of subcellular structures. Here, Sroka et al. develop in situ APEX activation (iAPEX) to overcome limitations of labeling specificity and H2O2 toxicity, app...
nature.com
While trying to steer clear of the ‘best organelle’ debate, we’re delighted to highlight #JCSciliaSI, guest edited by @cilialab.bsky.social & @lottepedersen.bsky.social. And, we hope that even the most ardent fans of other organelles can agree that cilia are certainly beautiful to image!
JCS Special Issue - 'Cilia and Flagella: from Basic Biology to Disease' - FocalPlane
JCS Special Issue - 'Cilia and Flagella: from Basic Biology to Disease' - News
focalplane.biologists.com
Akisato Marumo, Hiroto Ishii, Shin Yamaguchi, Junichiro Yajima and colleagues characterise the 3D beating pattern of the ciliary tip in the live ciliate Tetrahymena. #JCSciliaSI journals.biologists.com/jcs/article/... #OpenAccess #ReadandPublish
Registration is now open to attend Journal of Cell Science's meeting on Imaging Cell Dynamics, organised by Francesca Bottanelli, Guillaume Jacquemet, Michael Way and Giulia Zanetti. Find out more: biologists.com/meetings/jcs... #JCSimaging #Microscopy #Microscope #Imaging #Cells #CellScience
Mark Lee @guacamarklee.bsky.social and Keren Hilgendorf @uofubiochem.bsky.social discover that prostaglandin E2 inhibits adipogenesis through the cilia-dependent activation of ROCK2. #JCSciliaSI journals.biologists.com/jcs/article/...
🥳TheRaCil Publications Alert🚨Visit theracil.eu/news-and-pub... - cilia biology & perspectives for AI in nephrology👉KIF13B controls ciliary protein content, Rezi et al @lottepedersen.bsky.social 👉AI for diagnosis and care in rare kidney disease review, Chen et al @knebel.bsky.social #cilia #kidney
News and Publications - TheRaCil
theracil.eu
Malek Elsayyid, Alexis Semmel, Jessica Tanis and colleagues find that phosphatidylinositol 4,5-bisphosphate impacts extracellular vesicle shedding from C. elegans ciliated sensory neurons. #JCSciliaSI journals.biologists.com/jcs/article/...
Also in Issue 20: - Editorial from Pleasantine Mill @cilialab.bsky.social and Lotte Pedersen @lottepedersen.bsky.social. - 'Cell Scientist to Watch' interviews with Keren Hilgendorf and Girish Ram Mali @dyneinassembly.bsky.social journals.biologists.com/jcs/issue/13... #JCSciliaSI
Exciting news: the new review from @centriolelab.bsky.social is out in the amazing #JCSciliaSI! 🎉 I had the pleasure of working alongside Olivier Mercey, Paul Guichard and Virginie Hamel on this one. Cherry on top: our #UExM image was selected for the cover of the issue! 🤩
Advances in high-resolution imaging of centrioles and cilia
Summary: A review of the progressive advances in light and electron microscopy that have revealed unprecedented structural and molecular insights into centrioles and cilia, and reshaped our view of th...
journals.biologists.com
We are looking for: PhD Student (starting as Research Assistant) and Postdoctoral Researcher in Stem Cell Biology and Mechanobiology. Please RT💕 🔗 About our lab: renew.science/principal_in... 🎓 PhD position: jobportal.ku.dk/phd/?show=15... 🧪 Postdoc position: jobportal.ku.dk/videnskabeli...
This is our first submission to @jcellsci.bsky.social and the experience was fantastic. We will absolutely be submitting here in the future. Highly recommended.
We are thrilled to see this out in @jcellsci.bsky.social an in the special issue on Cilia. Cfap298 - which we call Kurly - is the mutant that keeps on giving us surprises! In this paper, a mutation generated by CRISPR, that deletes two aa and changes a third, specifically affects cilia motility.
Journal of Cell Science@jcellsci.bsky.social · 9mo agoMarvin Cortez, Cullen Young, Rebecca Burdine @rburdine1.bsky.social and colleagues identify a conserved domain in Cfap298 that governs left–right symmetry breaking in vertebrates. #JCSciliaSI journals.biologists.com/jcs/article/...