So useful!

DrLachie @drlachie.bsky.social · last wk.

Proud to present the publication of napari-lattice – our solution to the immense computational requirements of Lattice Light Sheet and Oblique Plane Microscopy. onlinelibrary.wiley.com/doi/10.1111/... Before I get into the thread, the important part is on github: github.com/BioimageAnal... (1/n)

📣 Come and say hello at stand #452 at #IMC21 to chat with our Editors and staff about publishing in the journal, open access options, and how we can help share your microscopy research with the wider community. We look forward to seeing you there!

🚨🚨🚨 napari 0.9.0 is out! 🚨🚨🚨 This is a huge release for us and for our community, with over 30 people contributing new features, improvements, and bug fixes in the 6 weeks since 0.8.0! Release notes here: napari.org/stable/relea... and some highlights in the thread below! 👇

napari 0.9.0

Tue, Aug 25, 2026 We’re happy to announce the release of napari 0.9.0! napari is a fast, interactive, multi-dimensional image viewer for Python. It’s designed for browsing, annotating, and analyzing l...

napari.org

Captivated by Kinesin - by Ron Vale published in Cytoskeleton onlinelibrary.wiley.com/doi/10.1002/... " In this essay, I reflect on how I first encountered kinesin and how it taught me to watch cells and proteins directly, letting observation reveal nature's workings."

A real buzz around this afternoon's poster session to round off a busy first day at #IMC21! Who's ready to go again tomorrow? 😀 🔬

Excited to see this collaboration now in print. Dye chemistry meets AI-designed proteins. Three small, orthogonal tags; lifetime modulation; split versions. Request the free dyes at dyes.janelia.org www.science.org/doi/10.1126/...

De novo design of orthogonal far-red, orange, and green fluorophore-binding proteins for multiplexed imaging

Fluorescent proteins and small-molecule dyes offer complementary advantages for biological imaging: proteins are amenable to genetic tagging, whereas dyes provide superior brightness and photostabilit...

science.org

This is a fantastic opportunity, I started my lab through this scheme and the support throughout is phenomenal, please share.

The Dunn School, Oxford@dunnschool.bsky.social · 2mo ago

Are you a postdoc interested in the mechanisms of disease? Do you have a great record and an exciting vision? Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships. Deadline 22nd of September...please share! www.path.ox.ac.uk/work-with-us...

UCL's Cell and Developmental Biology are hiring! Come and join us if you're interested in AI, computation and how they can lead to new biological discovery. www.ucl.ac.uk/work-at-ucl/...

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

ucl.ac.uk

If you haven't booked for #IMC21 in Liverpool this summer, now is the time to do so! Our 'Early Bird' discounted rates on a range of ticket options are available only until *TOMORROW* (Friday 17 July). Book now: https://www.imc21.org.uk/

Want to learn about the latest trends and developments in bioimage analysis? Join us for the GLOBIAS workshop in Dortmund this November! I will be hosting a session on foundation models / AI. www.globias.org/activities/g...

GloBIAS2026 Workshop Dortmund

GloBIAS 2026 Bioimage Analysts' Workshop Registration is open! Register with this link! 10-13 November, 2026 - Tuesday to Friday Leibniz-Institut für Analytische Wissenschaften – ISAS – e. V. (https...

globias.org

Don't forget abstract submission for late-breaking posters at #IMC21 closes *this Friday*(26th June). Great opportunity to share the most exciting, recent developments in #microscopy 🙂🔬 https://www.imc21.org.uk/congress/abstract-submission.html

📣Authors from eligible German institutions may publish #OpenAccess in the Journal of Microscopy with no article processing charge (APC) under the Wiley DEAL agreement!

There are lots of exciting opportunities to join the in situ structural biology community at Leeds this Autumn - 2 studentships in the Cheney PhD program (astbury.leeds.ac.uk/cheney-phd/) and I am recruiting a PhD student and research assistant. Please share and send any future tomographers our way!

Cheney Scholarship PhD Programme : The Astbury Centre for Structural Molecular Biology - "Understanding Life in Molecular Detail"

Applications are open for 2 PhD student places.  Closing date for applications is Thursday 26 June, 5pm. Interviews will be held on 9th July 2026. The Cheney Scholarship is a prestigious 4-year PhD pr...

astbury.leeds.ac.uk

Our June issue of infocus Magazine #RMSinfocus is now freely available to read online! Loads of great content - including a colourful preview of the 21st International Microscopy Congress (#IMC21) coming to Liverpool, UK, this summer! Read the issue: https://ow.ly/jQgg50Zanmt

Have you booked your ticket for the 21st International Microscopy Congress #IMC21, coming to Liverpool this summer? Don't miss this great event for the global #microscopy community 🙂🔬🌍 Book now: https://ow.ly/aSnB50Z2epE

Still time to register to join us next Friday in Leeds for our annual in-person UK Cilia and Centrosome Network in Leeds (05/06/2026)! Keynotes from the amazing @helenfoster.bsky.social & Fanni Gergely, plus latest breaking #cilia & #centrosome science. Register: www.eventbrite.co.uk/e/uk-cilia-c...

UK Cilia & Centrosomal Network Meeting Spring Meeting 2026

Join us for the annual in-person meeting of the UK Cilia & Centrosomal Network meeting, which for 2026 will be at the University of Leeds!

eventbrite.co.uk

An amazing experience! It was truly great to participate and co-organize the 3rd UK & Ireland SMBio symposium in Sheffield this week. Thanks to all 🙏 invited speakers: @gwuite.bsky.social,@slfort.bsky.social, @jwelburn.bsky.social, @akellett.bsky.social, @michellepeckham.bsky.social & Aakash Basu

Using iPALM to determine protein organisation in cardiac muscle Z-discs www.biorxiv.org/content/10.6...

Get the most from your Confocal microscope by booking your place on this excellent course! 🙂🔬 Great 2-day course covering the principles of confocal #microscopy, utilising many different sample types and fluorescent probes. https://ow.ly/758750YVqTn

tl;dr: MissAlignment learns to score misalignment then wiggles your alignments around to reduce that misalignment -> no more misalignment = high res STA 🌟 Watching @martenchaillet.bsky.social chip away at this was a real privilege! I’m excited to see this out and what you all will do with it 🙃

Dimitry Tegunov@dtegunov.bsky.social · 5mo ago

We're super excited to share MissAlignment: a new ML-based approach to reference-free tilt series alignment, spearheaded by @martenchaillet.bsky.social. We think it's going to make your cryo-ET life a lot better. Preprint: www.biorxiv.org/content/10.6... Code: github.com/warpem/miss-... 🧶 Thread:

Please repost! This comes from the good people at ChimeraX, who produce powerful up-to-date software to study protein (etc) structures, which are FREE to the community. 🙏 To stay viable and serve us, they need an experienced structural biologist to assume the leadership role on a funded project.

Faculty Position – In-Residence

University of California, San Francisco is hiring. Apply now!

aprecruit.ucsf.edu

Not just for microscopists, but relevant to all technical specialists. Making the invisible visible: A global examination of careers and recognition for Imaging Scientists in core facilities - Thompson - Journal of Microscopy - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...

Making the invisible visible: A global examination of careers and recognition for Imaging Scientists in core facilities

Modern life-science research relies heavily on advanced imaging technologies, from microscopes that reveal the structure of cells to imaging systems used in biomedical research. These instruments are...

onlinelibrary.wiley.com

New findings from CERN - as seen in the guardian - all about dark matter and its origins

🚨 New review out in @jmrcm-springer.bsky.social 🧬 From the @michellepeckham.bsky.social lab, we summarise how smooth muscle myosin is regulated—covering autoinhibition, filament assembly, and structural insights into motor control and disease. 👉 rdcu.be/feUiX

Smooth muscle contractile cytoskeleton in health and disease - Journal of Muscle Research and Cell Motility

Smooth muscle cells are widespread in the human body, found in a range of tissues from the vasculature to the gut, airways, bladder and so on. They can be found as isolated cells or organised into syncytia (groups of cells). The organisation of the contractile cytoskeleton (smooth muscle actin and myosin filaments) is less well understood than that of striated (cardiac and skeletal) muscle. This review aims to explore what is known, the potential effects of mutations in smooth muscle actin, myosin and tropomyosin and how they lead to disease, and to highlight what we have still to learn about the smooth muscle contractile cytoskeleton.

doi.org

🚨 New paper alert 🧬 Our work from the @michellepeckham.bsky.social lab is now out in #ScienceAdvances. We present the #cryoEM structure of shutdown human non-muscle myosin 2A, showing how ionic interactions stabilise auto-inhibition and how mutations disrupt this state. 👉 tinyurl.com/4de8teyh

Two manuscripts from the lab to catch up upon exploring aspects kinesin-1 regulation. First, our examining the role of cargo-adaptor binding in controlling kinesin-1 conformational dynamics and association with MAP7 is now a VOR @elife.bsky.social elifesciences.org/articles/109...

Kinesin-1 conformational dynamics are controlled by a cargo-sensitive TPR switch

Cargo-adaptor binding to the KLC-TPR domains binding triggers structural rearrangements that relieve kinesin-1 autoinhibition, enabling MAP7 recruitment, through an allosteric mechanism that connects ...

elifesciences.org

Fantastic opportunity for Early Career Researchers 😀 Sign up for the 'Science Slam' for the chance to represent the RMS at #IMC21 🔥

Royal Microscopical Society Early Career Researchers@rmsearlycareer.bsky.social · 5mo ago

An opportunity to share your research in a creative way and be in with a chance of being selected to represent the @royalmicrosoc.bsky.social at the #IMC21 Science Slam (plus a £200 travel grant for #IMC21 !). Or join us to watch the virtual pre-selection round! Register by the 30th April 2026 🔬

A big thank you to everyone for their support and encouragement, especially @carter-lab.bsky.social and @gaiapigino.bsky.social for their mentorship, and @takashiochi.bsky.social for nominating me!!

🧪 From ~2500 applications to various international microscopy workshops, we delineate fascinating regional patterns in research foci and microscopy usage across the globe. These data could help form the basis for tailoring microscopy workshop curricula to local needs. tinyurl.com/32c3fzvk

For the first time in a while I am going to this - any of my friends and colleagues going? www.grc.org/cytoskeletal...