Thrilled to share our paper "A conserved GTPase complex gates exocytosis for defence and parasitism across alveolates" Ciliates are fantastic to understand rhoptry exocytosis, and cryo-ET once again reveals so much🤩 Thanks to all who contributed. @martacova.bsky.social @yiweichang.bsky.social

Nature Microbiology@natmicrobiol.nature.com · last wk.

Out Now! A conserved GTPase complex gates exocytosis for defence and parasitism across alveolates #MicroSky

Join us for a journal club from the SPPIRIT Forum series on the 5th June! With @scottchisholm.bsky.social, the 1st author, we will discuss a preprint, in which he used the hyperLOPIT spatial proteomics to shed light on organelle biology in Plasmodium. Register on: tinyurl.com/3rjzh3m5

PhD opportunity at LMU Munich 🇩🇪 Join our lab to study the molecular and cellular biology of Apicomplexan parasites, with a focus on the apical complex, motility regulation, and post-translational modifications. Apply: elena.jimenez@lmu.de job-portal.lmu.de/jobposting/6...

📆 Join us for the scientific session of the ParaFrap Next Generation in Parasitology Workshop (May 18-21, 2026, Montpellier) ! 🧑‍🔬 Junior PIs will present their work. Registration is free but mandatory (includes lunch & coffee breaks). Spots are limited, register now! 👉 forms.gle/bYsb47iZG7pR...

🚨 Postdoc position 🚨 I’m moving back to Switzerland this summer to launch my lab at the University of Zurich and am recruiting a Postdoctoral Fellow (start: late 2026). Details & application: jobs.uzh.ch/job-vacancie.... Please share! 😊

UZH: Postdoc

The newly founded Cryptosporidium lab at the Institute of Parasitology focuses on the genetic and transcriptomic basis of parasite virulence and persistence in Cryptosporidium and is committed to incl...

jobs.uzh.ch

FYI were starting weird structure/evolution/biology stuff at Glasgow University! If you're interested let me know! Tell your friends! CRYO www.jobs.gla.ac.uk/job/research... BIOINFO www.jobs.gla.ac.uk/job/research... TECHNICIAN www.jobs.gla.ac.uk/job/technici... #science #hiring #evolution

A super detailed protocol + video on Cryo-ExM - Cryo-Expansion Microscopy, led by the labs of our former postdocs @marinelap.bsky.social & @ebertiaux.bsky.social. Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...

How does C2CD3 contribute to distal appendage formation in centrioles? @centriolelab.bsky.social show that C2CD3 acts as a central architectural organizer of the distal #centriole, bridging the luminal distal ring complex & peripheral appendage sites @plosbiology.org 🧪 plos.io/496XZuH

New preprint! Really excited to share our spatial proteomic study on Plasmodium falciparum schizonts . We used hyperLOPIT to map thousands of proteins—from apical invasion organelles to the infected red blood cell surface.

Ross Waller@rosswaller.bsky.social · 11mo ago

Excited to release the Herculean efforts of @scottchisholm.bsky.social &Co. defining the subcellular #hyperLOPIT spatial proteome of #Plasmodium schizonts. Proteomes defining 24 subcellular niches, including exported compartments in the blood cell, are identified. www.biorxiv.org/content/10.1...

Excited to release the Herculean efforts of @scottchisholm.bsky.social &Co. defining the subcellular #hyperLOPIT spatial proteome of #Plasmodium schizonts. Proteomes defining 24 subcellular niches, including exported compartments in the blood cell, are identified. www.biorxiv.org/content/10.1...

When Toxoplasma's conoid is literally unhinged 😅

PLOS Biology@plosbiology.org · 11mo ago

The conoid is a structure in #Apicomplexans that extrudes during egress, gliding motility & invasion. This study shows that the coiled-coil protein RNG2 tethers the conoid to the apical polar ring in #Toxoplasma and is essential for invasion @plosbiology.org 🧪 plos.io/489blpq

The conoid is a structure in #Apicomplexans that extrudes during egress, gliding motility & invasion. This study shows that the coiled-coil protein RNG2 tethers the conoid to the apical polar ring in #Toxoplasma and is essential for invasion @plosbiology.org 🧪 plos.io/489blpq

In French - Virginie on Swiss radio! 🎙️ She talks about our latest collab with @dudinlab.bsky.social and @gautamdey.bsky.social #UExM #ProtistsOnSky

Biology-UNIGE@biology-unige.bsky.social · 11mo ago

📻 Interview de Virginie Hamel du @centriolelab.bsky.social pour CQFD de la #RTS: Une méthode ouvre lʹaccès à lʹarchitecture interne du #plancton #microscopie #expansion www.rts.ch/audio-podcas... @mocel.bsky.social @sciencesunige.bsky.social @dudinlab.bsky.social

Who-cysts? OOCYSTS! That's right, it's almost time for ❄️Coccidia UK 2025❄️ Your one-stop shop (/conference) for all like-minded sporulating apicomplexan parasites! This year we're in London @crick.ac.uk, looking forward to welcoming parasitologists from across the UK. Register- tinyurl.com/4ny5bwu2

CoccidiaUK 2025 registration

DEADLINE FOR ABSTRACT SUBMISSION: NOVEMBER 7th Event Timing: December 8th 9am-5pm December 9th 9am-12pm Event Address: The Francis Crick Institute Questions? please email ada...

tinyurl.com

Last week I attended my first #EMBO #ParaFrap Host-Parasite Interaction meeting in Les Embiez 🇫🇷 I had an amazing time packed with great science and people 👨‍🔬👩‍🔬 Thank you to the organizers for the chance to talk about my work on Perkinsus 🦠🦪 and thank you to everyone for the support and kind words! 🥹

Had an incredible time at the MPM 🇺🇸! It was an honor to talk about my work on Perkinsus, especially at the Marine Biological Laboratory, a perfect venue for a marine parasite 🌊🦠 So great to see such a diverse range of parasites and topics this year! Thanks to everyone for the fantastic discussions!

🚨 New paper out! 🚨 🧬 Parasite sex as a discovery tool — new insights into Cryptosporidium virulence! Huge thanks to my co-authors, collaborators & mentors 🙌 #Parasites #Cryptosporidium #Genetics #InfectiousDiseases #ForwardGenetics www.sciencedirect.com/science/arti...

Genetic crosses reveal genomic loci responsible for virulence in Cryptosporidium parvum infection

The relationship between parasite genotype and pathogenesis is largely unknown for Cryptosporidium, a leading cause of diarrheal disease in children. …

sciencedirect.com

Transfection of the free-living alga Chromera velia enables direct comparisons with its parasitic apicomplexan relative, Toxoplasma gondii https://www.biorxiv.org/content/10.1101/2025.08.26.672290v1

Finally out! Did you ever wonder how a phylum with 10 core genes can make a conserved organelle? Read the paper! It's all about intrinsically disordered proteins! | PNAS www.pnas.org/doi/10.1073/...

Now available in a polished format! An important step toward accelerated functional genomics for the Cryptosporidium parasite. Brought to you by the incomparable @lucy-watson.bsky.social www.nature.com/articles/s41...

Targeted CRISPR screens reveal genes essential for Cryptosporidium survival in the host intestine - Nature Communications

Cryptosporidium is an important threat to public health, yet it lacks a robust genetic toolkit. Here, Watson et al. introduce a targeted CRISPR-based screening method to identify parasite genes that a...

nature.com

Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you! embl.wd103.myworkdayjobs.com/en-US/EMBL/j... With @dudinlab.bsky.social @embl.org @biology-unige.bsky.social @moorefound.bsky.social

Join our crazy beautiful project of ExM Atlas ! One more position to fill, this time for a Research Technician at @embl.org in @gautamdey.bsky.social lab. Come have fun with us !.

Gautam Dey@gautamdey.bsky.social · last yr.

Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you! embl.wd103.myworkdayjobs.com/en-US/EMBL/j... With @dudinlab.bsky.social @embl.org @biology-unige.bsky.social @moorefound.bsky.social

🚨 New EMBO Practical Course! Ultrastructure Expansion Microscopy: From Cells to Tissue 🔬 📅 20–24 Apr 2026 | 📍 EMBL Heidelberg Co-organised with @banterlegroup.bsky.social @gautamdey.bsky.social 💡 Register your interest to get notified when registration opens: 🔗 www.embl.org/about/info/c...

The anticipation is over, the MPM registration and abstract submission is open!!

ParasitesRule@parasitesrule.org · last yr.

Registration and Abstract submission for MPMXXXVI are now open! Abstract submission deadline is June 27th, get yours in quickly. @rmc9z.bsky.social @mjgubbels.bsky.social @omarharb.org 🔗https://www.parasitesrule.com/mpm-xxxvi

Check out our dispatch on apicomplexans that infect corals! www.sciencedirect.com/science/arti... These parasite-like partners have lost photosynthesis but retained chlorophyll... are they friend or foe? @currentbiology.bsky.social #protistsonsky #symbiosky #microsky #coralreefs

Cryptosporidium modifies intestinal microvilli through an exported virulence factor!! Phenomenal work from the newly DR’ed Elena Rodrigues www.biorxiv.org/content/10.1...

Cryptosporidium modifies intestinal microvilli through an exported virulence factor

Cryptosporidium is a common intestinal infection of vertebrates and a significant threat to public health. Within the epithelial layer of the intestine, the parasite invades and replicates. Infected cells are readily detected under the microscope by the presence of elongated microvilli, particularly around the vacuole where the parasite resides. Here, we identify a family of Cryptosporidium virulence factors that are exported into the host cell during infection and localise to the microvilli. We examine the trafficking and function of the most highly expressed family member, MVP1, which appears to control the elongation of microvilli through engagement of host EBP50 and CDC42. Remarkably, this mechanism closely mirrors that of an enteropathogenic Escherichia coli virulence factor, MAP, which is also known to drive host microvilli elongation during infection. This highlights a unique instance where eukaryotic and prokaryotic virulence factors have convergently evolved to modulate host actin structures through a similar mechanism. ### Competing Interest Statement The authors have declared no competing interest.

biorxiv.org

It's transfection time for Perkinsus marinus and chesapeaki ⚡🦠🧬⚡ Hoping to have some fluorescent parasites in the coming days 🔬 So exciting!! #ProtistOnSky

Dynamic remodeling of centrioles and the microtubule cytoskeleton in the lifecycle of chytrid fungi https://www.biorxiv.org/content/10.1101/2025.01.03.631223v1

Discover the wonders of 𝘗𝘦𝘳𝘬𝘪𝘯𝘴𝘶𝘴 🤩 This parasitic protist undergoes rapid #CellDivision : from a single sporangium to hundreds of motile zoospores. A stunning glimpse into the speed and precision of microbial life! 🌊🔬 Stay tuned for more 𝘗𝘦𝘳𝘬𝘪𝘯𝘴𝘶𝘴 insights! #CellBiology #ProtistsOnSky

Cambridge colleges 🎄