Audrey John MD PhD

@odomjohnlab.bsky.social

Infectious diseases physician, scientist, mentor, mom, Chief @CHOP_ID | lab goals: new ways to diagnose and treat infection | views my own | #PedsIDSky #IDSky #PedsSky

Among infants born at a Philadelphia health system, female newborns were less likely to receive the vitamin K shot — which helps prevent dangerous bleeding — than male newborns. The apparent reason: Parents cannot get male infants circumcised in-hospital if they refuse shot.

Why more male than female newborns may get the crucial vitamin K shot

Vitamin K lowers the risk of bleeding, including in a circumcision. That procedure may explain a disparity in which infants are more likely to get the shot.

sciencenews.org

The PIDS Foundation kicked off a 6-part webinar series on vaccine confidence and messaging. We are excited to share the fourth installment next Tuesday, June 16 at 1pm ET – Addressing Common Misconceptions About Vaccines: Part 2. Contact us for registration information.

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To explain this for my non-science followers. Such a proposal would be to create a black box around review of scientific proposals - this reduction in transparency is what you would do if you wanted to make political or partisan decisions about funding and not scientific ones

Jeremy Berg@jeremymberg.bsky.social · 2mo ago

I heard from several sources yesterday that NIH is planning to release a Request for Information (RFI) that apparently will include this: Scores and percentiles for NIH grant applications will not be shared with applicants although they will be provided to NIH program officers and staff. 1/3

Pleased to share our recent work on imported pediatric malaria cases in the US. A fabulous partnership across 9 children's hospitals. publications.aap.org/pediatrics/a...

Malaria in Children at 9 US Hospitals: 2016–2023

10.1542/6390324821112Video AbstractPEDS-VA_2025-0735566390324821112OBJECTIVES. This study set out to describe imported pediatric malaria in the United States over an 8-year period, including patient demographics, clinical outcomes, and risk factors for severe disease.METHODS. A retrospective descriptive study of pediatric patients treated for malaria at 9 hospitals in the United States from 2016 to 2023 was conducted to analyze patient demographics, clinical outcomes, and risk factors for severe malaria.RESULTS. A total of 171 children were treated across the 9 US hospitals included in this study from 2016 to 2023. Most patients had traveled to West Africa to visit friends and relatives. Fever was the most common symptom recorded (90%), and most reported at least 1 abdominal symptom (66%). Thirty-two percent of patients were diagnosed with severe malaria. No deaths occurred. Delayed diagnoses were common (26%), occurred at similar rates across all hospitals in the study, and were a risk factor for severe malaria.CONCLUSIONS. Delayed diagnoses of travel-acquired malaria were common for pediatric patients presenting to hospitals in the United States and are associated with higher risk for severe malaria, which is associated with longer hospitalizations and increased morbidity. Chemoprophylaxis against travel-acquired malaria and prompt diagnosis of imported cases are crucial to improving patient outcomes.

publications.aap.org

We are recruiting 1-2 postdoctoral fellows to investigate the specificity of human anti-influenza virus antibodies, and to determine how these antibodies impact global antigenic drift of influenza viruses. Join our lab at Penn in Philly. Reach out if you are interested in applying! Please repost!

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