Tell me about a complicated magazine. Try the 𝘓𝘰𝘯𝘥𝘰𝘯 𝘙𝘦𝘷𝘪𝘦𝘸 𝘰𝘧 𝘉𝘰𝘰𝘬𝘴 for three months, in print and online, for just £6. subscription.lrb.co.uk/offers/social

AD-SMART is inviting proposals for innovative, validated digital outcome measures to support a UK-wide platform trial evaluating Alzheimer’s disease therapeutics. Find out more and apply by 30 Aug: www.innovative-ctu.ucl.ac.uk/studies/all-...

so how’s it going with the Parkinson’s? you say and I start to say every moment bleeding to death around me but the therapist cautioned me yesterday don’t say dread call it discomfort you’re not in danger you’re uncomfortable ‘Smile’, a poem by Anne Carson. www.lrb.co.uk/the-paper/v4...

Anne Carson · Poem: ‘Smile’

lrb.co.uk

Guy on train reading Slaughterhouse 5 just had his coffee knocked out of his hand. #Soitgoes

Join us tomorrow, July 16 at #AAICForAll in London, UK! Register for this no-cost, single-day event to get updates & insights from the world’s largest meeting on dementia science. Learn more: alz.org/aaic-for-all

Among patients with newly diagnosed relapsing multiple sclerosis, rituximab was noninferior to ocrelizumab in preventing new or enlarging lesions on MRI. The risk of serious adverse events was similar in the two groups. Full OVERLORD-MS trial results and Research Summary: https://nej.md/3QJuaep

On our 250th birthday, celebrating the contribution of immigrants and international collaboration —46% of people with doctoral-level degrees working in US science and engineering fields are foreign-born

Read all of #theendofeverything in one day at the weekend. Brilliant and as good as #thesunkenlandbeginstoriseagain. As if the woods part of #TheBeginningofSpring was a whole novel… www.theguardian.com/books/2026/j...

The End of Everything by M John Harrison review – near-future visions from an SF master

This bleak but brilliant tale of enigmatic alien entities and slow social collapse exposes the terrifying insecurity of life right now

theguardian.com

Our comment in @thelancet.com on advantages & challenges of Multi-arm Multi-stage (#MAMS) platforms for Neurodegeneration inc. @cardiffunilib.bsky.social @edinburgh-uni.bsky.social @ucl.ac.uk @newcastleuni.bsky.social @imperialcollegeldn.bsky.social @ukdri.ac.uk www.thelancet.com/journals/lan...

Multi-arm multi-stage platform trials for neurological disease: accelerating progress

Neurological diseases are the worldwide leading cause of ill health and disability.1 Although substantial progress has been made, such as modulating the inflammatory component of multiple sclerosis,2 ...

thelancet.com

The UK National Institute for Health and Care Research developed a systematic drug prioritization pipeline to identify repurposed drug candidates for inclusion in a planned platform trial for clinical AD. The norepinephrine reuptake inhibitor atomoxetine came in #1. pubmed.ncbi.nlm.nih.gov/42186115/

12 June 1929 | A German Jewish girl, Anne Frank, was born in Frankfurt. In 1942, on her 13th birthday, she received an empty diary. She perished in Bergen-Belsen concentration camp in 1945. 'Human greatness does not lie in wealth or power, but in character & goodness.' (A.Frank)

Here is a gift link to Simon Schama's appreciation of David Hockney's life and art which we ran last year. It's an amazing piece and contains, as you might imagine, some spectacular pictures including an absolute corker of Hackney with Lucian Freud as.ft.com/r/f1473f70-0...

bradfordmuseums.org/cartwright-h...

The David Hockney Gallery - Bradford District Museums & Galleries

David Hockney was born in Bradford in 1937. In time to celebrate his 80th birthday in 2017 we have created a new permanent display of works by the internationally renowned artist at Cartwright Hall Ar...

bradfordmuseums.org

Work led by Mike David looking at #arousal and #synchrony in clinical #alzheimers disease through #pupillometry #fmri and #neuromelanin imaging of the #locuscoeruleus, the brain’s key #noradrenaline nucleus. el. Hopefully relevant for treatment. alz-journals.onlinelibrary.wiley.com/share/AARWJ2...

www.theatlantic.com/philosophy/2...

No, Artificial Intelligence Is Not Conscious

Taken to its logical conclusion, this line of thinking is absurd—and damning.

theatlantic.com

Henry Nowak’s father’s words outside court, who is probably the person we most need to hear from today.

Really happy to share the paper describing drug repurposing pipeline for an upcoming platform trial in clinical #Alzheimers disease with candidate selection through multidisciplinary international panel chaired by @suzanne-reeves.bsky.social. alz-journals.onlinelibrary.wiley.com/share/SIZN3I...

Our researchers at the UK DRI at Edinburgh are featured on the BBC today, highlighting how AI is transforming the search for treatments for neurodegenerative conditions 👏 Thank you to Steve, who generously shared his story and why research gives him hope 💙 www.bbc.co.uk/news/article...

AI used to speed up search for motor neurone disease drugs

Researchers hope the work will help identify affordable, effective drugs to treat conditions like MND.

bbc.co.uk

Do brain circuits really sit in a 'soup' of neuromodulators? Are neurons like soggy bits of bread soaked in signaling factors? Is the whole brain just squelching around in one big pool of warm modulators?

Stanford neurologists Michael Greicius and Victor Henderson explain what science knows about why women develop Alzheimer’s disease at higher rates than men—and the many things science doesn’t yet know. Learn more: med.stanford.edu/news/insight...

I teach this in my IP law class b/c when asked in an interview who owned the patent, Salk replied: "Well, the people, I would say. There is no patent. Could you patent the sun?" He looked for vaccine solutions his entire life…including a quest for a vaccine to prevent HIV from becoming AIDS.

Dr. Todd Arrington@btarrington.bsky.social · 4mo ago

On this day 70 years ago-May 1, 1956-the polio vaccine was first made widely available to the public. The vaccine’s developer, Dr. Jonas Salk, did not patent the vaccine so that it would remain available to as many people as possible in the US and internationally. Image: Harvey Georges/AP.

London is the fastest city in the world. Congratulations to Sebastian Sawe and Tigst Assefa for their incredible achievements, breaking both the men's and women's world records.

I always assumed that brain function had to line up with cytoarchitectonics. It turns out I was wrong. Human cortex, especially PFC, is tiled by chains of functional patches that subdivide and interlink architectonic areas into parallel processing streams. www.biorxiv.org/content/10.6...

🧠Sharing this Starter Pack again as the list has now reached 80 people! A great mix of Profs/PIs/Post-docs/PhDs/Technicians. Please re-post so it can reach a wider audience as I'm sure there are more of us out there ☺️🦋 go.bsky.app/S6FfsTp

🧠 Discover the Landmark Project @imperialcollegeldn.bsky.social, profiling over 400 human brain donations to develop technologies for predicting disease progression and drug response in Parkinson's More 👉 www.imperial.ac.uk/news/256397/... #WorldParkinsonsDay

A selection of participants from the REACT study at Imperial College London are attending initial clinics via Inuvi for tests that will make them 'trial-ready'. Funded by the Medical Research Council, the initiative supports the Dame Barbara Windsor Dementia Goals programme.

The Bluesky account for the Barbellion Prize has changed to @barbellionprize.bsky.social Do please follow! The submission window for authors and publisher is open from now until 1st September, and there are full details on the new website barbellionprize.org

The UK DRI at King’s College London is hiring a Research Associate to study ALS using multiomics, stem cell models and bioinformatics to uncover early disease signatures. Closing date: 28th April www.dementiaresearcher.nihr.ac.uk/job/research...

Research Associate: Molecular signatures of ALS pathology

UK DRI at King’s College London seeks a Research Associate to study ALS using multiomics, stem cell models & bioinformatics to uncover early disease mechanisms

dementiaresearcher.nihr.ac.uk

Am reading the brilliant #SuddenlySomethingClicked by Walter Murch. A great book for anyone who likes films but so insightful about so many aspects of working and thinking to make or do ANYthing. Fantastic.

Am reading the brilliant #SuddenlySomethingClicked by Walter Murch. A great book for anyone who likes films but so insightful about so many aspects of working and thinking to make or do ANYthing. Fantastic.