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RD PascualMarqui

@pascualmarqui.bsky.social

KEY Inst Brain-Mind Research @UniZurich neuroscience imaging connectivity EEG MEG oscillations +LORETA+ Lagged Coherence/PhaseSynch Multivar/HiOrder InfoFlow https://scholar.google.com/scholar?q=pascual-marqui https://www.uzh.ch/keyinst/

112 Posts255 Follower195 Folgt
Alina Studenova@studenova.bsky.social · 5d ago

When a TMS pulse was delivered during beta ERD, EMG motor evoked potentials (MEPs) were larger than during ERS, while the immediate TMS-evoked responses (iTEPs) were smaller. This means that beta ERD was associated with decreased cortical excitability and increased cortico-spinal excitability. Odd!🤔

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 2w ago

Opposing modulation of cortical and corticospinal excitability across movement-related beta stages https://www.biorxiv.org/content/10.64898/2026.07.28.741164v1

Ben Hayden@benhayden.bsky.social · 4w ago

Hard to overstate the importance of this paper. Acategoricality and mixed selectivity together kill a lot of sacred cows. For starters, place cells aren't real, in that they are not a meaningful category. They are just a thing we scrape out of the data. Scientists focus on them because...

Columbia University's Zuckerman Institute@zuckermanbrain.bsky.social · 4w ago

Scientists have long debated whether neurons are jacks of all trades or tend to specialize in one thing. Now @stefanofusi.bsky.social, @lorenzoposani.com & Liam Paninski present new evidence in @nature.com shedding light on how the brain performs complex tasks. tinyurl.com/yj3ew8en

Lorenzo Posani@lorenzoposani.com · 4w ago

Out today on @nature.com! Connecting neural specialization, population geometry, and their functional implications across the cortical hierarchy. So grateful for this beautiful and fun collaboration with @shuqiw.bsky.social, S Muscinelli, L Paninski, and @stefanofusi.bsky.social!

Rarely categorical, highly separable representations along the cortical hierarchy - Nature

Cortical circuits prioritize diversity over categorical structure, supporting a computational regime geared towards high-dimensional, highly separable neural representations.

nature.com

Martin Dresler@dresler.bsky.social · last mo.

Why do we forget our dreams? Dreams are the kind of experiences that in principle should stick well in memory: emotional and often bizarre. If we would encounter typical dream content during wakefulness, we would likely never forget it. Yet, we forget most dreams soon after awakening. (1/3)

Earl K. Miller@earlkmiller.bsky.social · last mo.

In visual learning, slower changes come from adjustments in connections between neurons, while faster changes come from intrinsic plasticity. Together, these two learning processes help the brain efficiently adapt to familiar information over time. www.nature.com/articles/s41... #neuroscience

Visual learning at fast and slow timescales is driven by distinct plasticity rules in primate inferotemporal cortex - Nature Communications

We rapidly distinguish familiar from novel objects, but how the brain learns this remains unclear. Using macaque inferotemporal cortex recordings and modeling, the authors show that familiarity learni...

nature.com

Roxana Zeraati@roxana-zeraati.bsky.social · last mo.

Our paper "Neural timescales from a computational perspective" is finally out in @natneuro.nature.com: www.nature.com/articles/s41... We discuss how computational models and methods can distill empirical observations on neural timescales into quantitative, testable theories of brain computation.

Neural timescales from a computational perspective - Nature Neuroscience

This review integrates computational approaches to provide a unified view on how data analysis methods, biophysical mechanistic models and machine learning approaches can help to uncover the origins a...

nature.com

Alina Studenova@studenova.bsky.social · last mo.

To be fair, Anthropic didn't say Claude is conscious. But I'm missing on the point why the found J-space is a global workspace and not just massive working memory?

Stanislas Dehaene@standehaene.bsky.social · last mo.

The global neuronal workspace (GNW) is currently the best documented neuroscience mechanism by which conscious processing arises in the human brain — and now Anthropic researchers have discovered a similar workspace inside their large language model ! www.anthropic.com/research/glo...

Richard Sever@richardsever.bsky.social · last mo.

“move from preprint to peer-reviewed publication leaves the central claims of most abstracts intact, indicating preprints are a reliable source…papers that were never posted as preprints were retracted at roughly twice the rate of those that were…” www.biorxiv.org/content/10.6...

Tracking claim changes from preprint to publication across 72,644 biomedical studies using large language models

Preprints now disseminate a large share of biomedical research before peer review. Because they have not yet passed peer review, some scientists regard preprint claims as unverified or potentially unr...

biorxiv.org

Andreas Strube@astrube.bsky.social · last mo.

Very happy to see this Review with @diegopizzagalli.bsky.social out in @cp-trendsneuro.bsky.social www.cell.com/trends/neuro... This piece brings together a lot of what we’ve been thinking on depression, predictive processing and EEG. Many thanks for the support from @sfb-trr-289.bsky.social

Brain rhythms of depression: A predictive processing perspective

Depression is marked by anhedonia, social withdrawal, and a diminished capacity to learn from positive experiences—features that can be framed within predictive processing. Here, we review findings fr...

cell.com

Alina Studenova@studenova.bsky.social · last mo.

Some neurons fire during certain phases of LFP oscillations, while some fire more when LFP oscillates at certain frequencies. V. cool!🤩 I appreciated the discussion about causality: do oscillations in LFP cause increased spiking, or does the change in spiking cause changes in the spectrum of LFP?

PLOS Biology@plosbiology.org · 2mo ago

This Primer explores a @plosbiology.org study showing that #neuronal firing is selectively tuned to oscillatory frequency, complementary to phase tuning, suggesting an additional dimension in how #brain rhythms may organize neural activity 🧪 Paper: plos.io/44odgVM Primer: plos.io/4eJ6bUI

Three possible interpretations of frequency tuning. Top: Oscillatory frequency changes in the local field potential (LFP) may directly modulate neuronal excitability, such that neurons that are selectively sensitive to a given frequency increase their firing rate. As a result, neuronal spiking exhibits a frequency-dependent tuning profile, with maximal firing near a preferred frequency. Middle: Alternatively, the relationship between oscillatory frequency and neuronal firing may be reciprocal. Changes in firing activity of frequency-sensitive neurons may themselves contribute to shifts in LFP frequency, particularly during transitions between network states (e.g., from slow- to fast-theta regimes). In this view, increased spiking may both reflect and participate in state-dependent changes in oscillatory dynamics. Bottom: A third possibility is that both oscillatory frequency and neuronal firing are co-modulated by a common factor, such as neuromodulatory input (e.g., acetylcholine), leading to correlated changes in both without a direct causal link between them.
Darya Frank@darya-frank.bsky.social · last mo.

📣 Thrilled to share our recent work in @natneuro.nature.com. Using direct recordings from the human hippocampus and visual cortex, we asked how the brain prepares to encode information when upcoming events are unpredictable, and what ripples do in that process. www.nature.com/articles/s41...

Human hippocampal ripples tune cortical responses based on predicted uncertainty - Nature Neuroscience

Using direct recordings from the human brain, Frank et al. show that hippocampal ripples increase ahead of unpredictable events and tune the visual cortex to respond faster and more strongly to surpri...

nature.com

Eleonora Bartoli@elebartoli.bsky.social · 2mo ago

Some neurons like to ride on slow LFP oscillations, regardless of their phase! This might represent a mechanism to coordinate neural activity and propagate information across brain circuits 🧠 amazing collaboration led by the super talented @zahrajourahmad.bsky.social and Andrew Watrous!

PLOS Biology@plosbiology.org · 2mo ago

Do #neurons show preferential firing at specific oscillatory frequencies? @elebartoli.bsky.social &co use recordings from neurosurgical patients to show that freq of oscillations modulates neuronal firing; implications for freq-targeted #NeuralStimulation @plosbiology.org 🧪 plos.io/44odgVM

Jourahmad et al. investigate how single-unit activity (SUA) relates to nearby local field potentials (LFP) in humans. The figure shows real data from a neuron exhibiting increased firing during low-frequency oscillations, illustrating frequency-specific tuning independent of phase.
Marc Slutzky@marcslutzky.bsky.social · 2mo ago

Our paper is now in print in Nature @nature.com. If you're interested in local field potentials, especially #high-gamma activity, and/or #spikes, check it out! TL;DR: High gamma is not mainly filtered spikes, but mainly summed nearby PSPs. www.nature.com/articles/s41...

Active dissociation of intracortical spiking and high gamma activity - Nature

A brain–machine interface is used in monkeys to investigate the biophysical underpinnings of cortical high gamma-band activity, a signal that is often studied in the context of many brain functions.

nature.com

Simon Fisher@profsimonfisher.bsky.social · 2mo ago

Researchers recorded from single neurons across frontotemporal cortex in 8 awake individuals during natural speech. They show how activities of collections of cells can capture syntactic & semantic properties of words, & also dynamically incorporate sentence context to encode combinatorial info. 🗣️🧠🧪

Mapping the neuronal building blocks of human language with language models - Nature

Wide-scale recordings reveal neurons in the human brain that encode fundamental components of language such as the grammatical relationships between words, their parts of speech and the...

nature.com