Lewis Stevens

@phylewgenetics.bsky.social

I like worms, genomes, & evolution. Postdoc in Tree of Life @ Wellcome Sanger Institute. He/him.

Very excited to see the first chapter of my PhD out on bioRxiv! It began as a rotation project and became a pivotal part of my PhD on beetles, adding a complementary macroevolutionary perspective to my second chapter on early-stage speciation in Indonesian herbivorous ladybird beetles.

bioRxiv Evolutionary Biology@biorxiv-evobio.bsky.social · 2w ago

338 coleopteran genomes reveal exceptional rearrangement variation compared to other insect orders https://www.biorxiv.org/content/10.64898/2026.07.17.739156v1

Are you ready for *the* meeting about the evolutionary biology of Caenorhabditis and other nematodes?? EvoWorm 2026 will be held at McMaster University from June 16–19 Abstract submission deadline: April 15 Registration deadline: June 1 Further details can be found at evoworm.org

New preprint! We unexpectedly discovered that some Caenorhabditis species delete parts of their somatic genome early in development, which fragments their chromosomes and eliminates key germline genes. Multiple lines of evidence suggest this bizarre process was present in the ancestors of C. elegans

Figure with three panels. Left: phylogenetic tree of Caenorhabditis species, highlighting those with programmed DNA elimination. Middle: plot showing chromosomal locations of eliminated DNA. Right: Images showing DNA fragments being eliminated during early development.
bioRxivpreprint@biorxivpreprint.bsky.social · 9mo ago

Programmed DNA elimination was present in the last common ancestor of Caenorhabditis nematodes https://www.biorxiv.org/content/10.1101/2025.10.23.681605v1

C. elegans is a real animal and we set out to understand how it comes to have its distinctive biogeography. Its ancestral center of diversity is in the higher elevation forests of Hawaii. Its closest relatives are spread across east Asia. Did they travel from Asia? [Preprint 🧵]

New preprint! We generate 40 new high-quality microsporidian genomes from infected arthropod hosts that were sequenced to create reference genomes by the Darwin Tree of Life project. 8 of our genomes are chromosome-level, and we’re able to generate Hi-C data for 7! 🧬 www.biorxiv.org/content/10.1...

Forty New Genomes Shed Light on Sexual Reproduction and the Origin of Tetraploidy in Microsporidia

Microsporidia are single-celled, obligately intracellular parasites with growing public health, agricultural, and economic importance. Despite this, Microsporidia remain relatively enigmatic, with man...

biorxiv.org

Delighted to have been awarded a BBSRC Fellowship to look at the genetics of how insects have adapted to living in freshwater habitats 🧬🦋🪰🪲🌊 Extremely grateful to all who have supported me over the years and excited to be at Liverpool with some great colleagues! www.ukri.org/news/9-milli...

£9 million investment fuels groundbreaking bioscience research

From unlocking the secrets of animal movement to tackling antimicrobial resistance, UK’s brightest bioscience minds are pushing the boundaries of innovation.

ukri.org

Very excited to share this collaborative work led by Kyriaki Neophytou. An extracellular Argonaute from a nematode parasite is transmitted to host cells and the non-vesicular form is functionally important (and now a vaccine candidate). An Argonaute vaccine... who would have thought.

bioRxivpreprint@biorxivpreprint.bsky.social · last yr.

A non-vesicular Argonaute protein is transmitted from nematode to mouse and is important for parasite survival https://www.biorxiv.org/content/10.1101/2025.04.01.646544v1