Tessera
Folgen

Paul Gardner

@ppgardne.bsky.social

Bioinformatics, RNA, benchmarking & educating to fund kayaking and fishing. Ōtepoti/Dunedin, Aotearoa/New Zealand. From Whāngārā.

723 Posts2421 Follower2412 Folgt
Brent Toderian@brenttoderian.bsky.social · 7d ago

“According to the finance ministry’s calculations, the cost to society of trips by car is close to one euro/km. On the other hand, every km travelled by bike yields societal gains of 60 euro cents thanks to the health benefits of cycling, transport efficiency gains, & lower infrastructure spending.”

Copenhagen Cycling Revolution: Lessons for Cities

Close to two-thirds of the city’s residents commute by bike to school or work every day.

theprogressplaybook.com

Paul Gardner@ppgardne.bsky.social · last wk.

What other sectors could the NZ Prime Minister brutally transform? --Brutally increase tomato production by halving water use? --Brutally improve literacy by closing libraries? --Brutally strengthen bridges by removing beams? --Brutally improve health by closing clinics?

Paul Gardner@ppgardne.bsky.social · last wk.

I walked the GENE 4th years through this story yesterday. They were suitably horrified. On a related note, how many retractions, links to papermills, research misconduct etc. should be allowed before the entirety of a group's work can be delisted from the academic record?

Paul Gardner@ppgardne.bsky.social · 3w ago

1/8 Systematic reviews and meta-analyses are at the top of the evidence hierarchy. They influence clinical practice, policy and future research. So I was surprised to find a series of 12 reviews with remarkably similar PRISMA literature-search figures.

Evidence pyramid from: https://commons.wikimedia.org/wiki/File:Research_design_and_evidence_-_Capho.svg
Sally Greaves@cardiokiwi.bsky.social · 2w ago

Following initial vaccination of a limited number of key native species, a further 23 have been deemed priority for vaccination, including the Rowi and Haast kiwi, the Southern Brown kiwi, black robin, hoiho/yellow-eyed penguin and pāteke/brown teal. www.stuff.co.nz/nz-news/3610...

Some of New Zealand’s rarest kiwi to be vaccinated as bird flu threat grows

Kiwi will now be vaccinated against bird flu after the Ministry for Primary Industries approved the second stage of the Department of Conservation’s vaccine plan.

stuff.co.nz

Paul Gardner@ppgardne.bsky.social · 3w ago

1/8 Systematic reviews and meta-analyses are at the top of the evidence hierarchy. They influence clinical practice, policy and future research. So I was surprised to find a series of 12 reviews with remarkably similar PRISMA literature-search figures.

Evidence pyramid from: https://commons.wikimedia.org/wiki/File:Research_design_and_evidence_-_Capho.svg
Paul Gardner@ppgardne.bsky.social · 3w ago

I spent months hunting for missing essential & highly conserved ncRNAs in avian genomes -- eventually we realized they were all on microchromosomes.

Earth BioGenome Project 🌍@ebpgenome.bsky.social · 4w ago

🐦 Why are bird genomes so difficult to assemble? Birds have dozens of tiny, gene-rich microchromosomes that are frequently fragmented, misplaced, or missing from genome assemblies despite containing important genetic information. 📖 Read the publication: lnkd.in/gar-GrKZ #BirdGenomics #Biodiversity

A promotional graphic on a black background featuring a collage of more than 30 brightly colored bird species from around the world, including birds-of-paradise, toucans, parrots, hummingbirds, flamingos, cranes, owls, kingfishers, waterfowl, raptors, and songbirds. The birds are arranged around the centered text, "MicroFinder Is Now Available," with "MicroFinder" in gold and "Is Now Available" in white. The image highlights the diversity of avian species and announces the release of the MicroFinder computational tool for improving bird genome assemblies.
Margot Finn@eicathomefinn.bsky.social · 3w ago

In an outspoken attack on the “incredibly profitable” but “completely unregulated” scientific publishing industry, Thomas Südhof...said he wanted to see US or European Union agencies establish minimum standards for journals that wish to describe themselves as “peer reviewed”. 1/3

‘Broken journal system’ needs government oversight, says Nobelist

Federal authorities should enforce minimum standards for peer review in ‘unregulated’ journal sector, argues Thomas Südhof

timeshighereducation.com

Torsten Schwede@torstenschwede.bsky.social · 4w ago

CASP17, the 17th Critical Assessment of Structure Prediction conference, will take place in person in Rome, Italy, December 1–5, 2026. Registration is open now. What is the state-of-the-art in predicting protein and RNA structures, immune complexes, and ligands? events.humanitix.com/casp17 🧪 #AI

CASP17

CASP17 - Critical Assessment of Structure Prediction 3D Structure of Proteins, RNA, and Complexes, Immune Complexes, Ligand Binding, Conformational Ensembles

events.humanitix.com

Paul Le Comte 🇳🇿🇨🇦📷@paullecomtephoto.nz · 2mo ago

Salvaged from Dunedin home renovations, State House demolitions & Otago Uni Bookshop remodeling, from recycled NZ native timber to bespoke bonkers charcuterie chopping boards. On my site real soon & heading to your kitchen.

Paul Le Comte 🇳🇿🇨🇦📷@paullecomtephoto.nz · 2mo ago

Because I’m an idiot & perfectionist they’re getting a 4th coat of oil. FWIW they’re perfect & ready to go, but why sell something that’s pretty good when they could be damned good.

openRxiv@openrxiv.bsky.social · 2mo ago

Introducing openRxiv Labs! 🔬 Growing from the strong foundation of bioRxiv & medRxiv, Labs is an experimental space for working with collaborators to push the boundaries of open scientific communication. 👉 Check it out and learn more: openrxiv.org/openrxiv-lab... #OpenScience #Preprints #Scicomm

Launching openRxiv Labs - openRxiv

Over the last thirteen years, bioRxiv and medRxiv have grown into widely used infrastructure for rapid research sharing in biology and medicine. The reliability and researcher-first values that have d...

openrxiv.org

Dan Garisto@dangaristo.bsky.social · 2mo ago

Unreliable and underperforming antibodies are a longstanding problem, so while the reveal of apparently manipulated antibody data in Thermo Fisher's catalog was a shock, the frustration it sparked among many researchers is perhaps no surprise. My reporting:

Science sleuths uncover more than 100 suspicious images in Thermo Fisher antibody catalogue

Scientists have long worried about the reliability of commercial antibodies, and the latest findings have sparked fresh concerns.

nature.com