Schneider lab
@sabschn.bsky.social
Structural biologist, nucleic acids, chemical biology, Group leader at the University of Munich (LMU)
Very sad to learn of the death of Ralf Seidel. He was a superb single molecule biophysicist--especially in studies of nucleic acid/protein complexes. www.physes.uni-leipzig.de/pdi/profil/n...
Nachruf auf Prof. Dr. Ralf Seidel
Mit tiefer Trauer nehmen wir Abschied von unserem Kollegen Professor Ralf Seidel. Er ist am 17. Juli 2026 plötzlich und völlig unerwartet verstorben. Sein Tod hinterlässt eine große Lücke. Wir vermiss...
physes.uni-leipzig.de
Nobel laureate Dorothy Hodgkin was born 116 years ago today. The legend among legends in crystallography, she cracked the 27 atom structure of penicillin, and then the 181 atom structure of vitamin B12, and THEN the 788 atom structure of insulin. tinyurl.com/yketyrn5 #WomenInSTEM #ChemSky #BioSky
Monarch of Crystallography: Dorothy Crowfoot Hodgkin and the Structure of Large Molecules.
Two scientists.Two crystallographers.Both successful, but one died young after her most significant discovery was snatched from her, while the other lived to a ripe old age after a string of ground-breaking discoveries and a Nobel Prize. The former, Rosalind Franklin, is a household name. But the latter, in spite of the foundational importance of her work, has always remained on the fringe of our cultural perception: Dorothy Crowfoot Hodgkin (1910-1994). It is one of the truly frustrating thing
tinyurl.com
The Shingles vaccine and reduction of dementia: a new natural experiment from Canada replicated 3 others and adds to this week's link to slowing of biological aging. erictopol.substack.com/p/spotlight-...
Spotlight on the Shingles Vaccine—Again!
Two new studies add to a remarkable body of evidence for benefit
erictopol.substack.com
What happens between Manuscript submission date & Manuscript acceptance date
📽️ 3 Questions for Pierre Stallforth A cluster perspective on chemistry, microbiomes, and the distant past. From microbial interactions to natural products reconstructed from ancient DNA, including Neanderthal dental calculus. ▶️ Watch the clip: www.youtube.com/watch?v=-Ei0...
THREE QUESTIONS FOR: Pierre Stallforth
YouTube video by Universität Jena
youtube.com
Super nice to wake up to the news that our paper on bidirectional communication in an ABC transporter has been selected as a Nature Communications Editors’ Highlight in “Structural biology, biochemistry and biophysics"! 🥳 🥳 🥳 www.nature.com/articles/s41... @microverse.bsky.social
Bidirectional communication between nucleotide and substrate binding sites in a type IV multidrug ABC transporter - Nature Communications
The communication hinge, found in type IV ABC transporters, forms a bidirectional communication between ATP- and substrate-binding sites. This is an unexplored allosteric pathway critical for function...
nature.com
Great work from my colleague and neighbor Shuo Gu and his team! #RNAsky #RNAbiology
Nature Structural & Molecular Biology@natsmb.nature.com · 9mo agoNew online: DICER1 hotspot mutation induces 3p microRNA gain of function via Argonaute strand switch
This work was a collaboration between our former Group Leader @zaminiqbal.bsky.social and colleagues at @sangerinstitute.bsky.social and the @uniofbath.bsky.social. Explore the full paper: www.science.org/doi/10.1126/...
Pre- and postantibiotic epoch: The historical spread of antimicrobial resistance
Plasmids are now the primary vectors of antimicrobial resistance, but our understanding of how human industrialisation of antibiotics influenced their evolution is limited by a paucity of data predati...
science.org
The final version of our article about PLD3 AMPylation is now out shorturl.at/iTxWx. One protein, many proteoforms. Congratulations to Laura and thanks to @marleenberouti.bsky.social @v-hornung.bsky.social @jaelab.bsky.social @hellmichgroup.bsky.social
New from our Pioneering Investigators collection 🎉 'Towards a hydrolysis stable artificial base pair with C-glycosides' by Stephanie Kath-Schorr (@kathlab.bsky.social) and colleagues. #OpenAccess 🔓
Towards a hydrolysis stable artificial base pair with C-glycosides
Artificial base-pairs expand the genetic alphabet and allow for site-specific labeling, for example with fluorophores or spin labels, thereby enhancing the capabilities of biomolecular sensing. We…
buff.ly
"m6A in the coding sequence: linking deposition, translation and decay" by Kathi Zarnack (@zarnack-group.bsky.social) & colleagues "This review explores [m6A in] mRNA decay, with a focus on the newly discovered CDS–m6A decay (CMD) pathway..." Read it here: authors.elsevier.com/sd/article/S...
Hier kann man sich noch anmelden für unsere Experimentalvorlesung mit JJ Chemistry: form.hhu.de/institut-fue... 🙂
Maus-Anmeldung
form.hhu.de
Heinrich-Heine-Universität Düsseldorf@hhu.de · 11mo ago🐭 3. Oktober: Türen auf mit der Maus Am 03.10.2025 findet wieder der Mausöffnertag statt! Daran teil nimmt auch die HHU: Um 11:00 Uhr können bis zu 150 Teilnehmende eine Experimentalvorlesung zum Thema "Seltene Erden" besuchen. 1/2 @daumannl.bsky.social
Our research has been engulfed by an endless torrent of lab leak conspiracy theories about the origin of the pandemic - even as the evidence for zoonosis has only grown stronger. This fuels anti-science agendas and erodes public trust. Now, we respond 👇 theconversation.com/how-conspira...
How conspiracy theories about COVID’s origins are hampering our ability to prevent the next pandemic
The COVID pandemic likely began when the virus jumped from animals to humans, and didn’t start in a lab. But false narratives continue to circulate.
theconversation.com
First copies of my book are here!! As a new faculty member, I realized that in addition to my research job, I also had a leadership job…and I wasn’t prepared for that. This book is the guide I wish I’d had then, with the goal of helping others now. jenheemstra.com/book
Our new article published in Chem. Science on improving protein contact by varying foldamer side chains is now available! pubs.rsc.org/en/content/a...
Structure-based design of an aromatic helical foldamer–protein interface
The starting point of this study is the solid state structure of a complex between human carbonic anhydrase II (HCAII) and a helically folded tetradecaamide aromatic foldamer with a nanomolar HCAII li...
pubs.rsc.org
I am very excited to share the second paper of my PhD published in @cp-cell.bsky.social. Many thanks to all co-authors, especially from Thomas Carell's group, and my supervisor @v-hornung.bsky.social for their great support and collaboration! www.cell.com/cell/fulltex...
Pseudouridine RNA avoids immune detection through impaired endolysosomal processing and TLR engagement
Toll-like receptors (TLRs) 7 and 8 detect RNA degradation products to sense infection. However, modified nucleosides common in self-RNA—most notably pseudouridine—evade recognition. This study finds t...
cell.com
Bei ihr trifft Fachwissen auf didaktische Kompetenz: Die Studierenden von Prof. Dr. Lena Daumann @daumannl.bsky.social aus der Chemie @hhu.de sind begeistert und haben sie für den #hhuLehrpreis2025 nominiert. 🧪
www.nature.com/articles/s41...
Near-infrared fluorogenic RNA for in vivo imaging and sensing - Nature Communications
Most of the available fluorogenic RNA approaches emit visible fluorescence, and there is a need for tools working at longer wavelengths. Here, the authors identify and modulate red fluorescent protein...
nature.com
Ready to join the #ChemBio community under the blue skies ? go.bsky.app/KLrTWoj
Huge congratulations to Andreas Marx on winning the Albrecht Kossel Preis 2024 of @gdchbiochem.bsky.social. An inspiring award lecture highlighting his diverse contributions to understanding DNA polymerases and PTMs as well as his discovery of a human RNA ligase.
When dealing with pseudoscience, the devil is in the detail - in this case, narrowing down a specific "Lab Leak" hypothesis. In Dr. Chan's @nytimes.com OpEd there is, however, a very specific hypothesis for COVID-19 origin. It's a prime example of conspiracism vs empiricism, so let's dive in. 🧵
Kristian G. Andersen@kgandersen.bsky.social · 2y agoOn the day of Dr. Fauci's testimony, @nytimes.com decides to run a deeply unethical OpEd with snazzy graphics and snappy headlines about the Lab Leak. The article itself contains multiple falsehoods and deep mischaracterizations. Let's take every point in turn 👇🧵 www.nytimes.com/interactive/...
RNA has taken center stage, with remarkable versatility, such as >400 drugs approved and many more to come. My conversation with Tom Cech, Nobel laureate, pioneer of RNA biology, with a new book called THE CATALYST, w/transcript erictopol.substack.com/p/tom-cech-r...
Tom Cech: RNA Takes Center Stage
Listen now (49 mins) | A pioneer and Nobel laureate for advancing the biology of RNA has a new book THE CATALYST
erictopol.substack.com
Thanks @skyview.social for existing (bsky doesn't love long threads). Here's the very informative thread by @kgandersen.bsky.social on the #OriginOfCovid. Nothing to add: there will always be missing data, but parsimony rulez. As he says, time to move on! skyview.social?url=https%3A...
A BlueSky thread by Kristian G. Andersen on Skyview
When dealing with pseudoscience, the devil is in the detail - in this case, narrowing down a specific
skyview.social
Pulitzer-prize-winning writer Michael Hiltzik from the @latimes.com is among the few voices left in mainstream media who have not lost the plot on political attacks on scientists. Chilling read: www.latimes.com/business/sto...
Column: After smearing Anthony Fauci, House Republicans proceed to defame a prominent vaccine scientist
Dr. Peter Hotez is a vaccination expert who has nothing to do with COVID. The GOP's COVID committee just put him in its crosshairs -- but why?
latimes.com
