Registration is open for the EVBO Virtual Workshop Funding Your Lab: sponsored by NanoEntek! Learn about ERC Starting, Consolidator & Synergy Grants, ERAnet, Leducq Networks of Excellence, and more. 🗓️ 29 June | 🕓 16:00 CET | 💻 Online 🔗 evbo.org/index.php/vi...

Virtual EVBO Workshop - European Vascular Biology Organisation

FUNDING YOUR LABResearch Grant Opportunities for Early Career PIs Practical guidance on major international funding schemes from experienced investigators and grant experts. Chair: Serena Zacchigna…

eur04.safelinks.protection.outlook.com

Dendritic cells shape and sustain fibroblast niches @cp-immunity.bsky.social www.cell.com/immunity/ful... www.cell.com/immunity/ful...

New launch of iMPACToR 2026/2027, a mentorship program designed to support early-career researchers in their academic development at Uppsala University MedFarm! 😊 - More information and sign up in the link! uu.se/en/departmen...

Happy to share that our latest work on VEGFR2 in lymphatic endothelium is published @natcomms.nature.com “VEGFR2 is required for VEGF-C–VEGFR3–PI3Kα-mediated sprouting lymphangiogenesis” tinyurl.com/47bns9pp This project has been a long journey for the lab @taijamakinenlab.bsky.social , A thread.

@oga-community.bsky.social @ycharos.bsky.social

Sholto David@sholtodavid.bsky.social · 3mo ago

Surprised to discover that Thermo Fisher appears to show a fake western blot for the validation of one of their p53 antibodies. I've added a diagram to show the very similar bands. This does not appear to be one of the "published figures" but their own internal data.

Surprised to discover that Thermo Fisher appears to show a fake western blot for the validation of one of their p53 antibodies. I've added a diagram to show the very similar bands. This does not appear to be one of the "published figures" but their own internal data.

PDPN marks lymphatic vessels & CAFs in the TME, but tumor-cell PDPN can also be a biomarker of a plastic lymphatic metastasis–permissive state in TNBC🔬(key fatures of the PDPN state mouse–human conserved). Hypoxia → PDPN⁺ tumour cells → CCR7⁺ lymphatic spread. BJC: www.nature.com/articles/s41...

Podoplanin-defined tumour plasticity and CCR7-mediated lymphatic metastasis in triple-negative breast cancer - British Journal of Cancer

British Journal of Cancer - Podoplanin-defined tumour plasticity and CCR7-mediated lymphatic metastasis in triple-negative breast cancer

nature.com

Iruela-Arispe highlights new work by @petrovalab.bsky.social (rupress.org/jem/article/...) showing that endothelial cells actively regulate energy storage in white adipose tissue through MYCT1–IFITM2/3-dependent control of endolysosomal trafficking & mTORC1 signaling. rupress.org/jem/article/...

Wetterwald, Köck et al. @petrovalab.bsky.social report the existence of an endothelial metabolic checkpoint where MYCT1 restricts activity of IFITM2/3 to prevent energy waste at the vascular barrier and enable fat storage. rupress.org/jem/article/... 🎥 See video summary: youtu.be/SGZ-5GiZvrI

🌟Today in Nature Cancer! Stromal cells and chemokine gradients organize the loss of tissue architecture in lymph nodes in B cell lymphoma ✒️Judith B. Zaugg, Daniel Hübschmann, Simon Haas & Sascha Dietrich & colleagues www.nature.com/articles/s43...

Reprogramming of stroma-derived chemokine networks drives the loss of tissue organization in nodal B cell lymphoma - Nature Cancer

Czernilofsky et al. identified factors that reprogram stromal cells into an inflammatory, dysfunctional state, leading to the structural disorganization of lymph nodes in B cell lymphoma at single-cel...

nature.com

🔬 From our March issue: rupress.org/jem/issue/22... Confocal laser microscopy image of ileal GALT labeled for CCL19 RNA (green) & podoplanin (red). From a study "Fibroblast diversity within human gut-associated lymphoid tissues," by @ursmoerbe.bsky.social and colleagues: rupress.org/jem/article/...

Intestinal lymphatic vasculature is functionally adapted to different drainage regions and is altered by #helminth infection. From Jorden Lane, Daria Esterházy and colleagues: rupress.org/jem/article/... 📘 In our #Lymphatics collection: rupress.org/jem/collecti...

See our collection of the latest discoveries in lymphatic biology: rupress.org/jem/collecti...

Lymphatic Vessels in Health and Disease 2026 | Journal of Experimental Medicine | Rockefeller University Press

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rupress.org

Registration is open for the AngioScience Conference (19-22 Sept) and Young Investigators Meeting (18-19 Sept) a.k.a. the Kloster Seeon meeting Meeting website: www.vwfb.de

Oral cancers with a high risk of recurrence can be identified at an early stage by examining the lymphatic vessels of the tumour. The high number of proliferating lymphatic vessels predicted cancer recurrence and death better than any other previously known risk factor for oral cancer. #MedSky

Aggressive oral cancer can be identified at an early stage by changes in lymphatic vessels

Oral cancers with a high risk of recurrence can be identified at an early stage by examining the lymphatic vessels of the tumour.

utu.fi

New paper alert 🚨 We are delighted to present our latest paper in @natcomms.nature.com through fabulous work from co-first authors Sebastian Braun and Paulina Bolivar! Big thanks to all expert collaborators for taking this long journey with us! Tweetorial in comments 🧵 www.nature.com/articles/s41...

Pericytes orchestrate a tumor-restraining microenvironment in glioblastoma - Nature Communications

Improved understanding of the tumor ecosystem in glioblastoma is critical for developing new treatment strategies for the disease. Here, the authors identify pericytes as an active paracrine signaling...

nature.com

🌟14th EFIS-EJI TATRA Immunology Conference 💡Proudly supported by #EFIS and @eurjimmunol.bsky.social 🤝organized by the 🇦🇹,🇨🇿+🇸🇰 Immunological Societies 📚unites Europe’s rising #immunology stars since 1994 👉 tatra.img.cas.cz Be part of this community shaping the future of immunology & spread the word!

Today is #WorldCancerDay ~1 in 5 people will develop #cancer in their lifetime Each diagnosis affects not just one person, but families, communities, and futures Grateful today for patients, clinicians, researchers & advocates - and to appreciate that progress depends on acting together #WCD2026

A key finding of our last study is that soluble and immobilized CCL21 gradients cooperate to fine-tune different steps of lymphatic migration, revealing a new layer in leukocyte guidance. This work was only possible thanks to an amazing team effort!

Journal of Cell Biology@jcb.org · 6mo ago

uPA-mediated remodeling of CCL21 gradients regulates lymphatic migration of dendritic cells. New study from Victor Collado-Diaz, Maria-Nefeli Christakopoulou, Philipp Schineis, Cornelia Halin @halinlab.bsky.social @ethz.ch and colleagues: rupress.org/jcb/article/... #Immunology #Migration #motility

uPA-mediated remodeling of CCL21 gradients regulates lymphatic migration of dendritic cells. New study from Victor Collado-Diaz, Maria-Nefeli Christakopoulou, Philipp Schineis, Cornelia Halin @halinlab.bsky.social @ethz.ch and colleagues: rupress.org/jcb/article/... #Immunology #Migration #motility

An update to the Hallmarks of Cancer framework for understanding (and researching) what causes human cancers. spkl.io/63321Aqwbc Douglas Hanahan @cp-cell.bsky.social

Nature research paper: Fibroblastic reticular cells direct the initiation of T cell responses via CD44 go.nature.com/4qxGBXl

Fibroblastic reticular cells direct the initiation of T cell responses via CD44 - Nature

CD44 expressed by fibroblastic reticular cells in secondary lymphoid organs regulates trafficking of dendritic cells, and thus has an essential role in the priming of T cells and the adaptive immune response.

go.nature.com

Fibroblastic reticular cells direct the initiation of T cell responses via CD44 @nature.com @the-de-lab.bsky.social www.nature.com/articles/s41...

We’re delighted to see this out today! Latest work from the lab reveals insights into the evolution of brain immunity and the developmental and evolutionary plasticity of lymphatic endothelial cells. www.nature.com/articles/s41...

Convergent evolution of scavenger cell development at brain borders - Nature

Transcription factor osr2 is identified as a specific marker and regulator of mural lymphatic endothelial cell (muLEC) differentiation and maintenance, and muLECs and border-associated macrophages sha...

nature.com

New paper out from the @kpietraslab.bsky.social lab. I am happy to share that my first-author paper is now published. We map the spatial and temporal dynamics of cancer-associated fibroblasts in breast cancer using integrated spatial proteomics and transcriptomics. link.springer.com/article/10.1...

Spatial and temporal dynamics of cancer-associated fibroblast niches in breast cancer - Breast Cancer Research

Breast Cancer Research - Cancer-associated fibroblasts (CAFs) are the main constituents of the tumor microenvironment. Several studies have delineated CAF heterogeneity in different types of...

link.springer.com

Danish PhDs - possibility to join Uppsala University as postdoc! Deadline 29th of Jan - My lab has an open project for a candidate who wants to study how the specialized vascular and stromal cells in lymph nodes shape the immune response in aging & cancer. novonordiskfonden.dk/en/grant/pos...

Postdoctoral Fellowships at Uppsala University - 2026 - Novo Nordisk Fonden

novonordiskfonden.dk

Oscillatory shear-activated mTORC1 in Lymphatic Valve Morphogenesis & Homeostasis Adult 🐭mesenteric Lymphatic Valve EC is more proliferative than capillary EC, indie of VEGFA/C Flt4+ LEC Tsc1 KO in P1-5🐭➡️⏫Valve size/density at P10 @petrovalab.bsky.social #JCB 2023 rupress.org/jcb/article/...

One of the most-viewed PNAS articles in the last week is “Tattoo ink induces inflammation in the draining lymph node and alters the immune response to vaccination.” Explore the article here: https://ow.ly/zhn450XGvmW For more trending articles, visit https://ow.ly/7BgF50XGvmV.

Comparative analysis of commercial Imaging-based #SpatialTranscriptomics methods Xenium CosMx 1k MERSCOPE Tissue Microarray 17 tumor+16 normal tissue Transcript count vs Reference RNAseq Segmentation accuracy Cell type annotation #NatComms 2025 www.nature.com/articles/s41...