🌟Today in Nature Cancer! Stromal cells and chemokine gradients organize the loss of tissue architecture in lymph nodes in B cell lymphoma ✒️Judith B. Zaugg, Daniel Hübschmann, Simon Haas & Sascha Dietrich & colleagues www.nature.com/articles/s43...

Reprogramming of stroma-derived chemokine networks drives the loss of tissue organization in nodal B cell lymphoma - Nature Cancer

Czernilofsky et al. identified factors that reprogram stromal cells into an inflammatory, dysfunctional state, leading to the structural disorganization of lymph nodes in B cell lymphoma at single-cel...

nature.com

Very early days, but delighted that our recent review on reevaluation of aging hematopoiesis published in Experimental Hematology, official journal of @isehsociety.bsky.social is classified as highly cited by web of science. Open access here: www.exphem.org/article/S030...

Reconsidering the usual suspects in age-related hematologic disorders: is stem cell dysfunction a root cause of aging?

The global trend toward an increasing aged population demographic raises significant societal challenges, particularly concerning health. As organisms age, progressive tissue dysfunction increases the...

exphem.org

Ein gutes #Forschungsumfeld ist die Grundlage guter #Wissenschaft. 🌱Gemeinsam mit der @volkswagenstiftung.de suchen wir 2026 erneut die besten Forschungsumfelder! Bewerbungsfrist: 01.03.2026 Preis: 5 Teams erhalten je 10.000 € ➡️ Infos: www.diejungeakademie.de/de/projekte/... @haniharb.bsky.social

ONLINE FIRST ALERT! Molecular #Plasticity Results in #Oncofetal #Reprogramming and Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia aacrjournals.org/bloodcancerd... @aacrjournals.bsky.social #childhoodcancer #epigenetics #precisiononcology

Had a great time welcoming visitors into our labs for @berlinscienceweek.bsky.social! It's always inspiring (and important!) to share our research with the public, and to see so much curiosity for how and why we do science 🧪🧬 Photos © Marc Beckmann / Berlin Science Week

Our latest work is out in Nature today. In this paper, we introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the somatic mutation landscape of oral epithelium in >1000 people www.nature.com/articles/s41...

Somatic mutation and selection at population scale - Nature

A new version of nanorate DNA&nbsp;sequencing, with an&nbsp;error rate&nbsp;lower than five errors&nbsp;per billion base pairs&nbsp;and compatible with whole-exome and targeted capture, enables epidemiological-scale studies of somatic mutation and selection&nbsp;and&nbsp;the generation of high-resolution&nbsp;selection&nbsp;maps across coding and non-coding sites for many genes.

nature.com

🚀 WE ARE HIRING 3️⃣ Independent Group Leaders for #mdcBerlin's new cutting-edge Bioengineering Cluster within our Biomedical Engineering Program. Lead cutting-edge research at the interface of biology, engineering, and medicine in Berlin. 👉 Apply now: www.mdc-berlin.de/career/jobs/...

In an analysis of 1.2 million news stories about scholarly research, men-led papers were found to receive more attention overall and were heavily overrepresented in the top 5% of most covered studies. https://scim.ag/4o7l5a5

When women researchers publish, media attention doesn’t always follow

Men-led papers receive more media coverage than women’s, new study finds

scim.ag

Excited to share the latest publication from my PhD with @simonhaas.bsky.social at @dkfz.bsky.social, out now in Nature Methods! A big thanks to all co-authors, especially Lea Jopp-Saile, Schayan Yousefian and @viktoriaflore.bsky.social for all their hard work. www.nature.com/articles/s41...

Ultra-high-scale cytometry-based cellular interaction mapping - Nature Methods

Interact-omics, a high-throughput cytometry-based framework, resolves the cellular interaction landscape.

nature.com

🧬 How do immune cells talk – and what happens when they don’t? A new technology by Simon Haas & Daniel Hübschmann maps millions of cell contacts 🔬 It shows how immune responses shift in disease & therapy. 📊 A step toward personalized medicine! 🔗 Read more: www.mdc-berlin.de/news/press/h...

Ein Team aus Forschenden vom BIH, @mdc-berlin.bsky.social, DKFZ, HI-STEM und @qmul.bsky.social hat eine Technologie zur Entschlüsselung der Immunzell-Kommunikation entwickelt. Damit lässt sich unter anderem ablesen, warum Immuntherapien bei manchen Menschen wirken bei anderen nicht. t1p.de/w3v16

Wie Immunzellen kommunizieren, um Krankheiten und Krebs zu bekämpfen

Ein interdisziplinäres Team aus Wissenschaftlerinnen und Wissenschaftlern vom Berlin Institute of Health in der Charité (BIH), vom Max Delbrück Center, dem Deutschen Krebsforschungszentrum (DKFZ), dem...

t1p.de

Excited to share our latest paper @natmethods.nature.com We present a high-throughput framework to map cellular interactions at ultra-high scale – broadly applicable from whole-organism immune response mapping to personalized therapy response prediction (1/4). www.nature.com/articles/s41...

Did you ever wonder what insights hide in the multiplets that are usually discarded in flow cytometry? 🫧 Find out in the first publication of my PhD, now out in Nature Methods! www.nature.com/articles/s41... (1/4)

Ultra-high-scale cytometry-based cellular interaction mapping - Nature Methods

Interact-omics, a high-throughput cytometry-based framework, resolves the cellular interaction landscape.

nature.com

Nature Methods@natmethods.nature.com · 12mo ago

For a quick summary, read the Research Briefing here: www.nature.com/articles/s41...

Today is June 25. On this date in 1903 Marie Curie defended her doctoral thesis on radioactive substances at Université de la Sorbonne in Paris, becoming 1st woman in France to receive a doctoral degree. Image shows the thesis cover.

So proud that the Single Cell Focus Area was selected as one of the winners of the "Best Research Environment 2024" award!

Max Delbrück Center@mdc-berlin.bsky.social · last yr.

💡 Great science needs great environments. We are proud that our Single Cell Focus Area is among the ten “Best Research Environments 2024” – selected by @jungeakademie.bsky.social‬ together with the @volkswagenstiftung.de. Congratulations! 🥳 More details: 👉 www.diejungeakademie.de/en/press/bes... 👈

🏆 Die 10 Gewinnerteams des Preises „Bestes #Forschungsumfeld 2024“ stehen fest! Aus fast 300 Bewerbungen wurden sie aus einer beeindruckenden Shortlist per Los gezogen. Wir gratulieren gemeinsam mit der @volkswagenstiftung.de! 🎉 Wer gewonnen hat? 👉 www.diejungeakademie.de/de/presse/be...

Excited to see our team among the finalists for the Best Research Environment award by the Junge Akademie! Fingers crossed for the draw 🤞

Die Junge Akademie@jungeakademie.bsky.social · last yr.

🧬Unter den Top 24 der besten Forschungsumfelder ist auch die Single #Cell Focus Area. Sie vereint die Forschung der Charité Berlin, des @bihatcharite.bsky.social, des @mdc-bimsb.bsky.social und des @mdc-berlin.bsky.social. Der Preis wird im Juni ausgelost. 👉 www.diejungeakademie.de/de/projekte/...

Hey #HemeSky and #EpiSci folks! We are hiring! For our Translational Cancer Epigenomics team @dkfz.bsky.social and @nct-heidelberg.bsky.social we are looking for a talented postdoc interested in research on heme malignancies and #epigenetics. Interested? 👉See jobs.dkfz.de/en/jobs/1676... or DM me!

Postdoctoral Researcher

jobs.dkfz.de

Now online! Optimizing stem cell infusion timing in the prevention of acute graft-versus-host disease

Optimizing stem cell infusion timing in the prevention of acute graft-versus-host disease

Adjusting the timing of stem cell infusion can reduce the incidence and severity of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. The rhythmic fluctuations in inflammation levels before infusion dictate subsequent T cell responses, which may be a key factor underlying outcomes based on the time of day that transplantation occurs.

dlvr.it

We polled Nature readers to ask if they were thinking of leaving the US for jobs abroad. Three-quarters of them (who said they were US-based scientists) said yes. 🧪 www.nature.com/articles/d41...

75% of US scientists who answered Nature poll consider leaving

More than 1,600 readers answered our poll; many said they were looking for jobs in Europe and Canada.

nature.com

Thrilled to share new work led by @jieyang437.bsky.social in the lab published today in @Nature. We find that Aspirin prevents metastasis by releasing T cells from immune suppression by platelet TXA2. @Cambridge_Uni @CRUKCamCentre rdcu.be/eci1U

Hey #LifeScience community have you seen that @altmetric.com now includes Bluesky as attention source 🎉 Bluesky is becoming a great place to share research and engage in scientific discussions! 🔬💬 #AcademicChatter #AcademicSky #AcademicBluesky #SciComm #ECRChat #PhDSky #MedSky

🎉 bioRxiv & medRxiv are now managed by openRxiv, a new independent nonprofit. This transition allows for more flexibility and innovation. Our mission remains being a free service to authors ensuring rapid sharing of scientific information before peer review. ℹ️ openrxiv.org/introducing-...

Introducing openRxiv: a new independent home for preprint sharing in the life sciences - openRxiv

We’re thrilled to announce the launch of openRxiv as an independent nonprofit to oversee bioRxiv and medRxiv, the world’s leading preprint servers for life and health sciences. openRxiv ensures that r...

openrxiv.org

A special issue on #WomensHealth in #ScienceAdvances highlights a growing wave of research focusing on women’s unique biological and psychological experiences. Learn more: scim.ag/3R59fPe (THREAD 🧵)

As we can expect PubMed dysfunction more and more or to be swamped with fake journals I suggest you get acquainted to this nice alternative: europepmc.org

Great teamwork with co-lead Niels Weinhold (@HDMyeloma) and a fantastic effort led by Raphael Lutz, Alexandra Poos, Llorenç Solé Boldo, Lukas John, and many others. Grateful for such an incredible team! 👏 #TeamScience 2/2

How does multiple myeloma progress? In our latest Science Immunology cover story, we reveal how myeloma cells breaking through bone trigger dangerous diversity. This arises from bidirectional interactions with the immune system, fueling disease evolution. scim.ag/4hMrLHs 1/2

Zooming in on how multiple myeloma starts to spread in the body: Single-cell analyses and spatial omics allowed international researchers, including the @simonhaas.bsky.social lab at the #mdcBerlin, to see a co-evolution of blood cancer and immune cells. #ScienceImmunology More details 👇

When blood cancer starts to spread

When blood cancer cells break through the bone and multiply, tumor cells become dangerously diverse and the immune response in the region changes, researchers from Berlin and Heidelberg report in “Sci...

mdc-berlin.de

When asked to draw a scientist, school-age kids in the United States are increasingly sketching women, according to a study from 2018. Read more on #WomenInScienceDay: https://scim.ag/4hOUuvx

New pre-print from Thomas Höfer, Daniel Hübschmann, @haas_lab and myself, with first authors @Esther_RCorrea @FloGrunschlager and Tamar Nizharadze doi.org/10.1101/2025... @DKFZ @NCT_HD @ChariteBerlin @hi_stem_lab BIH & MDC

A kinetics-based model of hematopoiesis reveals extrinsic regulation of skewed lineage output from stem cells

Residing at the top of the hematopoietic hierarchy, long-term hematopoietic stem cells (HSCs) are capable of self-renewal and sustained blood cell regeneration. Over the past decades, single-cell and ...

doi.org