Alex Matia
@alexmatia.bsky.social
Postdoc fellow investigating the mechanisms of viral neuropathogenesis @StanfordMed and @CZBiohub | PhD in Poxvirus ☣️ @CSIC #viromics #poxrocks #flavis
How worried should you be about West Nile virus? Berkeley public health professor Dr. Justin Remais discusses how to protect yourself from this mosquito-borne disease, as he notes another sharp rise in California’s West Nile virus activity. bit.ly/4cn0JpV
How worried should you be about West Nile virus?
Dr. Justin Remais of the UC Berkeley School of Public Health on how to protect yourself from this mosquito-borne disease.
bit.ly
Very high WNV activity this year in California 🦟 Take care out there! ...and report dead birds here: westnile.ca.gov
Mosquito-borne diseases are breaking records as climate change and other human influences allow the insects to expand their range go.nature.com/4x6xhMK
How mosquitoes are conquering the world — in four charts
Mosquito-borne diseases are breaking records as climate change and other human influences allow the insects to expand their range.
go.nature.com
Excited to share our new review! 🎉 Together with @rhuttenhain.bsky.social, we discuss how emerging proteomics approaches are revealing the spatial and temporal organization of the cellular proteome. Great fun writing this together! www.sciencedirect.com/science/arti...
Resolving cellular signaling in space and time: From organelle proteomics to spatial phosphoproteomics
Cellular signaling is inherently organized in space and time, requiring coordinated control of protein localization, molecular interactions, and enzym…
sciencedirect.com
Ruth Huttenhain@rhuttenhain.bsky.social · 4w agoExcited to share our new review in Current Opinion in Chemical Biology! We discuss how advances in proteomics are transforming our understanding of where, when, and how signaling occurs in cells. Thanks to @alexmatia.bsky.social for writing the article with me. www.sciencedirect.com/science/arti...
Preprint out! We optimized synchro-PASEF for phosphoproteomics & found equivalent biological insights to dia-PASEF despite fewer total IDs. Practical tip: apply retention time summation factor 2 to any PASEF phosphoproteomics data—you'll gain IDs and precision. www.biorxiv.org/content/10.6...
Systematic optimization and benchmarking of synchro-PASEF for high-throughput phosphoproteome profiling
High-throughput data-independent acquisition (DIA) workflows paired with short chromatographic separations are increasingly adopted for systems biology and clinical proteomics. However, narrower peak ...
biorxiv.org
V-SWITCH: A single-vector OFF-to-ON fluorescent reporter of live RNA virus infections https://www.biorxiv.org/content/10.64898/2026.04.08.717260v1
Despite decades of intensive research, current approaches to treating #NeurodegenerativeDiseases only slow down the seemingly inevitable. Could recent data associating #vaccines with reduced risk of #dementia offer an unexpected beacon of hope?🧪 @sparrerlab.bsky.social
Could targeting viruses be a new hope against neurodegenerative diseases?
Current therapies for neurodegenerative diseases largely manage symptoms and only modestly slow progression. This Perspective highlights emerging evidence that vaccines and antivirals may lower…
plos.io
Not all West Nile virus lineages behave alike: vector competence and minimum infectious dose differences between lineages 1 and 2 https://www.biorxiv.org/content/10.64898/2026.02.03.700853v1
NEW PAPER OUT! Pathogenicity assessment of Spanish West Nile virus isolates of lineages 1 and 2 in a Swiss mouse model doi.org/10.1016/j.ve...
Check out our new preprint! We uncover the full molecular mechanism of rotavirus membrane penetration and cytosolic escape using cryo-ET, live-cell imaging, and single-molecule assays. (1/3) 🔗 biorxiv.org/content/10.6...
Austria, Spain, and several other countries just lost their measles elimination status too.
📢 Abstract submission is now open for ViBioM 2026 in Vilnius!! Share your work and be part of the conference in May! #virology #bioinformatics #ViBioM2026 🎤 Talk Abstract Deadline: 6 March 2026 📜 Poster Title Deadline: 17 April 2026 🔗 evbc.uni-jena.de/events/vibio...
Sadly, another country is losing its measles elimination status for a virus whose vaccine is highly effective. www.bbc.com/news/article...
UK loses measles elimination status
Decision made after outbreaks in 2024, when there were nearly 3,000 cases in England and Wales.
bbc.com
Weekly respiratory viruses update: - #influenza circulation HIGH, but has peaked - #RSV circulation ELEVATED and increasing and increasing - #SARSCoV2 circulation remains at LOW levels. More info: erviss.org #ERVISS #RespiratoryViruses #IDsky #EpiSky #COVID19
Thrilled to share the first major preprint from the lab. Viruses are classically viewed as targets of host sensing. Do viruses also sense and respond to the host? We propose viruses may act as “biosensors” of the host signaling state. A thread👇🏾 www.biorxiv.org/content/10.1...
Global Landscape of Human Kinase Motifs in Viral Proteomes
Viruses are classically viewed as targets of host sensing, yet whether they also sense and respond to host cues remains largely unexplored. We propose that host-driven post-translational modification ...
biorxiv.org
The subclade K of influenza virus is currently 80% of the H3N2 circulating worldwide nextstrain.org/seasonal-flu...
West Nile death reported in California The death, in a county where high numbers of West Nile virus-positive mosquitoes and dead birds have been found, is the fifth West Nile-related death in the state this year.
West Nile death reported in California
It's the fifth West Nile virus-related death in the state this year.
cidrap.umn.edu
Europe's record mosquito-borne disease activity could signal new normal Rising temperatures, longer summers, milder winters, and changing rainfall patterns are creating more favorable conditions for mosquito populations. www.cidrap.umn.edu/c... Photo: Judy Gallagher/Flickr cc
If you love #viruses, #ribosomes, and genomic #darkmatter, this thread is for you!! 💫 We're excited to share our new publication developing Massively Parallel Ribosome Profiling (MPRP), which uncovered ~4,000 hidden proteins in ~700 viral genomes. www.science.org/doi/10.1126/...
🚨 Out now! Distinct non-canonical translation initiation modes arise for specific host and viral mRNAs during poxvirus-induced shutoff #MicroSky 🦠 #NorthwesternUniversity #FeinbergSchoolofMedicine www.nature.com/articles/s41...
Distinct non-canonical translation initiation modes arise for specific host and viral mRNAs during poxvirus-induced shutoff - Nature Microbiology
During poxvirus-induced shutoff, certain cellular and viral mRNAs continue to be translated through distinct modes of non-canonical initiation, in part due to altered ribosome activity, to produce hos...
nature.com
Vietnam reports H5N1 avian flu case with encephalitis Tests on respiratory samples were negative, but results were positive for the cerebrospinal fluid sample. www.cidrap.umn.edu/a...
Out now at @nature.com The entry receptor for enterovirus D68 👀 www.nature.com/articles/s41...
MFSD6 is an entry receptor for enterovirus D68 - Nature
Nature - MFSD6 is an entry receptor for enterovirus D68
nature.com
Aging might not be enough to eliminate H5N1 viruses in raw-milk cheese. #H5N1 www.cidrap.umn.edu/avian-influe...
Aging might not be enough to eliminate H5N1 viruses in raw-milk cheese
cidrap.umn.edu
📣Measles is an extremely contagious virus. Make sure you and your family are up to date on your measles vaccine to stay protected. 📲 Find more vaccination information at: cdph.ca.gov/Programs/CID/DCDC/Pages/Immunization/family.aspx. #Measles #Vaccinate #StayHealthy #HealthyCA4All
We're hiring! Join the Blythe lab as a full-time junior researcher starting Summer 2025. Explore GPCR trafficking and signaling using biochemistry, cell biology, and proteomics. Mentorship, hands-on experience, and career growth await! Apply now: hr.myu.umn.edu/jobs/ext/367... (UMN job ID #367053)
Because there's not enough going on: Arizona has found #H5N1 #birdflu in milk and it looks like yet another spillover from wild birds. www.statnews.com/2025/02/14/a...
Bird flu found in Arizona milk suggests another spillover from birds to cows
Another spillover of the H5N1 bird flu virus from wild birds to dairy cattle appears to have occurred, this time in Arizona.
statnews.com
Vaccines work! As measles cases have recently been reported in Alaska, Georgia, New York, Rhode Island and Texas, it's important to remember that prior to the introduction of the measles vaccine in 1963, measles killed 400-500 people and resulted in ~48,000 hospitalizations per year.
🚨 🌟 Submissions & Registrations Open for #ViBioM2025! 🌟 🚨 Join us 13–15 May 2025 in Lisbon, Portugal! 🦠💻 Present your research, connect with global experts, and shape the future of #Virology & #Bioinformatics. 📅 Details & links: evbc.uni-jena.de/events/vibio...
