‘Big changes’: Crick to stop paying for hybrid open access. www.researchprofessionalnews.com/rr-news-uk-o...

‘Big changes’: Crick to stop paying for hybrid open access - Research Professional News

Leading biomedical research institute says it will “go full in on green and gold”

researchprofessionalnews.com

Can GNNs really learn biology, or just graph topology? Our new preprint shows that GNNs predict gene essentiality better only when using real biological interaction networks. Biological network organization, not generic graph topology, drives prediction. www.biorxiv.org/content/10.6...

For over 50 years, EMBL has led breakthroughs in European life sciences. Now, we are among those leading the AI revolution in biology. Powered by the passion of multidisciplinary experts, we integrate AI throughout our work and transform life’s complexity into new possibilities. #EMBL_AI

For our first #MSS2026 session after lunch, the focus was on digitizing gene regulation 💻 Three fantastic talks from Anthony Mathelier @amathelier.bsky.social @ncmbm.bsky.social, Boris Lenhard @borislenhard.bsky.social and Tom Michoel from @cbubergen.bsky.social 👏

Glad to attend and speak at the Michael Sars Symposium 2026 #MSS2026 co-organized by @msarscentre.bsky.social and Computational Biology Unit, Bergen at University of Bergen. Looking forward to a great day of science. @ncmbm.bsky.social @embl.org @nordicembl.bsky.social

🎉 The CBGR group turns 10! We just celebrated with collaborators, colleagues, friends & family. This milestone belongs to everyone involved; too many to name, but every single one of you made it happen. 🙏 Here's to the next 10 years! 🥂 @uio.no @nordicembl.bsky.social @ncmbm.bsky.social

Discover exciting new publications in the latest edition of Highlights in Cancer Research! Our Highlights in Cancer Research is a summary of the most interesting & impactful papers in cancer research, curated by the EACR Board. Read more in The Cancer Researcher: magazine.eacr.org/highlights-i...

Upcoming cancer epigenetics conference in Paris (Oct 13-16, 2026). Consider registering: www.atoutcom.com/cancer-epige...

This a very important, and extremely well-executed study from Ralph Grand’s group @uniheidelberg.bsky.social. Congrats to all the authors! www.biorxiv.org/content/10.6...

ELIXIR @elixir-europe.org will soon be looking for a new director! elixir-europe.org/news/directo...

ELIXIR - Europe's distributed research infrastructure for life science data - is recruiting a new Director elixir-europe.org/news/directo...

Have you registered yet for #MSS2026? Join us to hear @amathelier.bsky.social from @ncmbm.bsky.social share his team’s latest work mapping transcription factor-DNA interactions across species, and much more 👏 We look forward to seeing you there! ➡️ tinyurl.com/JoinMSS2026 @cbubergen.bsky.social

“the preprint movement [is] a response to the failures of the open access movement…All the more reason to be mindful of our past missteps” scholarlykitchen.sspnet.org/2026/04/14/g... via @madubs.bsky.social

Guest Post - From Open Access to Preprints: Are We Repeating the Same Mistakes in Scholarly Publishing? - The Scholarly Kitchen

Guest blogger Jonny Coates looks at Richard Poynder's post-mortem on the Open Access movement, and uses it as a framework to ask questions about the future of preprints.

scholarlykitchen.sspnet.org

Tumor promotion through the lens of evolution This review grew out of many long conversations, shared ideas, and lively discussions It has been a real pleasure to think together with Allan, Paul, Eve, and Abel about how tumours develop and how carcinogens shape cancer risk rdcu.be/fdC2J

Tumour promotion through the lens of evolution

Nature - This Review revisits tumour initiation and promotion in light of clonal diversity and the presence of cancer driver mutations in normal tissues, aiming to understand mechanisms that enable...

rdcu.be

Very happy to land in beautiful Bergen to attend the ELIXIR Norway annual All Hands Meeting @elixir-europe.org. Three exciting days ahead discussing ELIXIR Norway's contributions to support life science researchers with bioinformatics services, data management tools, and secure e-infrastructure.

Proud to have taken a part of this great work!

Chymkowitch lab@chymkowitchlab.bsky.social · 5mo ago

Excited to share that our latest research has been published in @narjournal.bsky.social Read the article here: academic.oup.com/nar/article/... Congratulations to Patrizia Nothnagel and many thanks to all people involved including Nolwenn Briand, Bjørn Steen Skålhegg and @amathelier.bsky.social.

Excited to share that our latest research has been published in @narjournal.bsky.social Read the article here: academic.oup.com/nar/article/... Congratulations to Patrizia Nothnagel and many thanks to all people involved including Nolwenn Briand, Bjørn Steen Skålhegg and @amathelier.bsky.social.

👇 Still a couple of days to apply to join our amazing team as a Research Scientist / Software Developer. Apply if you want to build and maintain reproducible pipelines for large-scale genomic analysis to support our study of breast cancer cis-regulatory signatures and JASPAR, among other things.

Anthony Mathelier@amathelier.bsky.social · 6mo ago

📢 Hiring! Our group @ncmbm.bsky.social seeks a Research Scientist contributing to: • Reproducible pipelines for large-scale genomics • cisreg signature analysis in breast cancer • Continued development of JASPAR • Cross-disciplinary collaboration Apply now 👉 www.jobbnorge.no/en/available...

The TFBS tracks for 8 species using JASPAR 2026 TF binding profiles are now available as native tracks on the UCSC genome browser @genomebrowser.bsky.social ! genome.ucsc.edu/goldenPath/n...

Ever notice that when one gene is disrupted, its orthologs get upregulated? This phenomenon, known as transcriptional adaptation, has been controversial and mysterious - glad to see that we are starting to learn how it works.

Mechanisms linking cytoplasmic decay of translation-defective mRNA to transcriptional adaptation

Transcriptional adaptation (TA) is a genetic robustness mechanism through which mutant messenger RNA (mRNA) decay induces sequence-dependent up-regulation of so-called adapting genes. How cytoplasmica...

science.org

📢 Hiring! Our group @ncmbm.bsky.social seeks a Research Scientist contributing to: • Reproducible pipelines for large-scale genomics • cisreg signature analysis in breast cancer • Continued development of JASPAR • Cross-disciplinary collaboration Apply now 👉 www.jobbnorge.no/en/available...

Looking forward to two days of talks and discussions around research and innovation in Life Science in Norway! @uio.no

Looking forward to participating in this symposium! Thanks for the invitation.

Michael Sars Centre@msarscentre.bsky.social · 6mo ago

We are thrilled to announce that registration is now open for the Michael Sars Symposium 2026, co-organized with @cbubergen.bsky.social 🙌 Join us on June 4 in Bergen for a day of fantastic talks, with a focus on living systems in a variable ocean 🌊 🔗 tinyurl.com/joinMSS2026

We are thrilled to announce the first official release (v0.1.8) of #𝗯𝗲𝗱𝗱𝗲𝗿, the successor to one of our flagship tool, #𝗯𝗲𝗱𝘁𝗼𝗼𝗹𝘀! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen. 1/n

AlphaGenome is out in @nature.com today along with model weights! 🧬 📄 Paper: www.nature.com/articles/s41... 💻 Weights: github.com/google-deepm... Getting here wasn’t a straight path. We discussed the story behind the model, paper & API in the following roundtable: youtu.be/V8lhUqKqzUc

Thanks to @ferhatay.bsky.social and Aly Khan, we’re excited to announce a new chapter for RECOMB-RSG 2026. After years with ISCB/DREAM, we are transitioning to an official RECOMB satellite meeting (May 25 in Thessaloniki). recomb-rsg.github.io

Excited to see the upcoming new chapter for RECOMB-RSG 2026. After years with ISCB/DREAM, it is transitioning to an official RECOMB satellite meeting (May 25 in Thessaloniki). recomb-rsg.github.io 1/3

You swear at the code. You’re sure the computer’s being stupid. But it’s not the computer. It never was. 🧵

Took this photo 12 years ago

inMOTIFin is now published in Bioinformatics! 🎉 It lets you generate random sequences and TF motifs, and insert motif instances with custom spacing, co‑occurrence and orientation. Use cases for de novo motif discovery, cooperative TF binding, and DL explainability. academic.oup.com/bioinformati...

inMOTIFin: a lightweight end-to-end simulation software for regulatory sequences

AbstractSummary. The accurate development, assessment, interpretation, and benchmarking of bioinformatics frameworks for analyzing transcriptional regulato

academic.oup.com

Anthony Mathelier@amathelier.bsky.social · last yr.

🚨 New preprint from group is now out on arXiv. inMOTIFin: A lightweight, flexible simulation toolkit for regulatory genomics. Simulate, implant, and modify transcription factor binding motifs with ease. 🔗 arxiv.org/abs/2506.20769 🧵👇