📣 Funded PhD studentship in developmental neuroscience in my lab @exeter.ac.uk 🧠🧑‍🎓 Join us to decode RNA processing in developing mammalian cortical circuits! All info + apply 👉 www.exeter.ac.uk/study/fundin... ⏳Deadline: 28th Feb 2026 | Please share! #PhD #Neuroscience #Neurodevelopment #RNASky

PhD studentship: Building Brain Cir | University of Exeter

The University of Exeter’s Department of Clinical and Biomedical Sciences is inviting applications for a faculty-funded PhD studentship to commence on September 21st 2026 or as soon as possible therea...

exeter.ac.uk

📣 We're hiring a postdoc to join our growing team @exeter.ac.uk! Love developmental neurobiology, RNA regulation & cortical circuits? This might be for you 🧑‍🔬 Apply here 👉 tinyurl.com/2d659uj7 Please share!

We have a fully funded PhD studentship exploring glial cell development with techniques ranging from molecular neuroscience to system biology. tinyurl.com/2jxezabw Come and join our interdisciplinary team with Ruth Williams and Beatriz Bano Otalaro #multiomics #singlecell #physiology

It was a pleasure writing this Perspective of our work. If you are interested in learning more about activity-dependent regulation of cortical cell numbers, do have a read. tinyurl.com/4ede4jyb

✨ Are you a pre-tenure faculty or advanced postdoc with an academic offer in hand? 🎓 Two weeks left to apply for the SDB New Faculty Boot Camp! 🚀 Deadline: Aug 22, 2025 Apply here 👉 tinyurl.com/SDBFaculty

Monika is such an amazing scientist. It has been such a privilege to see this story grow and develop during my time at @marinlab.bsky.social. I am so happy to see this finally out. Well done to all authors. @martijnselten.bsky.social @clembrnrd.bsky.social

Oscar Marín Lab@marinlab.bsky.social · last yr.

1/10 Our latest research, led by Monika Moissidis, identifies a mechanism regulating the maturation of PV interneurons in the #cortex. This is the story @cellcellpress.bsky.social www.cell.com/cell/fulltex... ⬇︎ thread @devneuro.bsky.social @kingsioppn.bsky.social @wellcometrust.bsky.social

The paper is out in journal format at EJN! We thank the reviewers for their insightful comments, and how they shaped the final form of this story. Check it out here: onlinelibrary.wiley.com/doi/10.1111/... As usual, it's open access! We're getting the data ready for sharing very soon 👀🧠🧪

Functional Maturation and Experience‐Dependent Plasticity in Adult‐Born Olfactory Bulb Dopaminergic Neurons

Adult-born dopaminergic neurons in the mouse olfactory bulb are almost functionally mature at 5 weeks of cellular age. More immature adult-born dopaminergic cells do not have elevated functional ...

onlinelibrary.wiley.com

Grubb Lab@grubblabneuro.bsky.social · 2y ago

We have *another* preprint! This work was led by the amazing Candida Tufo, ex-PhD student in the lab. We show that adult-born dopaminergic cells in the olfactory bulb rapidly functionally resemble their pre-existing counterparts! Have a look at the preprint here: www.biorxiv.org/content/10.1...

Now out in @natneuro.nature.com: Temporal control of progenitor competence shapes maturation in GABAergic neuron development in mice. Congrats to first authors @annrosebright.bsky.social, Yana Kotlyarenko, @flo-neuhaus.bsky.social, and thanks to all collaborators! www.nature.com/articles/s41... 1/n

Temporal control of progenitor competence shapes maturation in GABAergic neuron development in mice - Nature Neuroscience

Unlike cortical progenitors, ventral telencephalic progenitors retain the ability to generate diverse neuron types during neurogenesis. Here, the authors show that ventral telencephalic progenitor mat...

nature.com

Dr. Katie Long is leading vital research, funded by an MRF award, to learn how pregnant people feel about vaccines during pregnancy. We want your views! Take this short survey: tinyurl.com/vaccines-in-... For more information on vaccines in pregnancy visit tommys.org/vaccinations-pregnancy

New paper in @oxfordacademic.bsky.social Schizophrenia Bulletin exploring the effects of Setd1a happloinsufficiency on DNA methylation in the frontal cortex. Strong effects on the regulation of ribosomal genes with implications for understanding the genetics of schizophrenia. doi.org/10.1093/schb...

Setd1a Loss-of-function Disrupts Epigenetic Regulation of Ribosomal Genes via Altered DNA Methylation

AbstractBackground and Hypothesis. SETD1A, a histone methyltransferase, is implicated in schizophrenia through rare loss-of-function mutations. While SETD1

doi.org

Here is the collective effort of 12 labs, lead by my own at the Broad to target the range of cortical interneuron subtypes! These tools should be a game changer for all of you using NHP and other less genetically amenable species! Have at it! urldefense.proofpoint.com/v2/url?u=htt...

One thousand candidate enhancers tested in vivo in the mouse brain! A massive resource and oh so useful as validation set for genome-wide enhancer prediction methods. Super fun to be involved in one of the papers: ‘the prediction challenge paper’ by Nelson&Niklas et al www.cell.com/cell-genomic...

Evaluating methods for the prediction of cell-type-specific enhancers in the mammalian cortex

Johansen et al. report the results of a community challenge to predict functional enhancers targeting specific brain cell types. By comparing multi-omics machine learning approaches using in vivo data...

cell.com

allen institute@alleninstitute.org · last yr.

In the battle against brain disease, researchers can now rely on a new arsenal of genetic tools – The Armamentarium. Together with scientists from across the NIH BRAIN Initiative, we’ve created and published over 1000 new enhancer AAV vectors. 🧠📈

My first post on Bluesky! Very excited to share our work just published in @science.org. We find that “Interphase cell morphology defines the mode, symmetry, and outcome of mitosis” - in angiogenesis and other tissues! www.science.org/doi/abs/10.1... www.science.org/doi/abs/10.1...

Interphase cell morphology defines the mode, symmetry, and outcome of mitosis

During tissue formation, dynamic cell shape changes drive morphogenesis while asymmetric divisions create cellular diversity. We found that the shifts in cell morphology that shape tissues could conco...

science.org

🚨Paper Alert🚨 Our paper on the mechanism of homeostatic control in PV interneuron activity is now online in Nature! A massive thanks to all the authors, including @clembrnrd.bsky.social and @marinlab.bsky.social. Read the paper at www.nature.com/articles/s41....

Regulation of PV interneuron plasticity by neuropeptide-encoding genes - Nature

Increasing the activity of individual parvalbumin-expressing interneurons in the mouse brain modulates the number and strength of inhibitory parvalbumin synapses received by these cells through c...

nature.com

Oscar Marín Lab@marinlab.bsky.social · last yr.

1/10 Our latest research, led by @martijnselten.bsky.social, identifies a mechanism through which Parvalbumin (PV) interneurons regulate their activity in the #cortex. This is the story @nature.com www.nature.com/articles/s41... ⬇︎ 🧵 @devneuro.bsky.social @kingsioppn.bsky.social @erc.europa.eu

So excited to share our first neuro focused paper from the lab, we show that CXCL4 (PF4) is transported into the brain by proteoglycans within the endothelial glycocalyx and that GAG binding also mediates the pro neurogenesis effects of CXCL4. www.biorxiv.org/content/10.1...

I will soon start recruiting for a Wellcome-funded postdoc position! I’ll be at the #BNA2025 meeting next week. If you like cortical development, wiring, and post-transcriptional regulation, do get in touch and we can have a chat in Liverpool! 😀

Job alert 🚨 We are hiring a research assistant! This 7-year position available @exeter.ac.uk from Sept 2025 will involve keeping the lab running as well as contributing to our research activities on brain development. Full details tinyurl.com/23nyds34. Please spread the word!

⏳🧠 Developmental timing is key during neocortex development. Our new review with @takashi-namba.bsky.social lab discusses the role of epigenetic and metabolic regulation of developmental timing in neocortex evolution. www.sciencedirect.com/science/arti...

Epigenetic and metabolic regulation of developmental timing in neocortex evolution

The human brain is characterized by impressive cognitive abilities. The neocortex is the seat of higher cognition, and neocortex expansion is a hallma…

sciencedirect.com

Advances in neuroscience have yielded massive, rich datasets from various analysis techniques and modalities. 🧠📈 In a @natureneuro.bsky.social perspective, researchers underscore the importance of an integrative approach to render a more complete picture of the brain.

Integrating multimodal data to understand cortical circuit architecture and function - Nature Neuroscience

This paper discusses how experimental and computational studies integrating multimodal data, such as RNA expression, connectivity and neural activity, are advancing our understanding of the architectu...

nature.com

I absolutely love this beginners guide to scientific conferences by @jens-cells.bsky.social. It's not only useful for beginners either- there is lots of great advice even for those of us who have been attending conferences since the last millenium. thenode.biologists.com/the-beginner...

the-beginners-guide-to-scientific-conferences

The Beginners Guide to Scientific Conferences

thenode.biologists.com

We are showcasing our love for developmental biology for British Science Week this year with the different model organisms that we use in our division. 🪰🐸🐟🐣🐭🧠🔬🧬🧫

Fun paper celebrations across the developmental biology and @mcf-uom.bsky.social groupings this afternoon. Celebrating our latest paper and papers from the @brainotopia.bsky.social @lovegrovelab.bsky.social, Herbert, Manning, Bennett and Papalopulu labs. Congrats to all!

Are you an undergraduate student considering a career in academic research? Don’t miss the opportunity to gain hands-on experience at the LMB with our Student Placement Scheme – open now for applications! Apply by 30th March. More info: www2.mrc-lmb.cam.ac.uk/students/stu...

Multiple group leader positions in developmental biology in @ibdm.bsky.social Marseille, at an institute that produces some great work.

We Are Recruiting Group Leaders - IBDM | Institut de Biologie du Développement de Marseille

The Institut de Biologie du Développement de Marseille (IBDM) is inviting applications for group leader positions. We are seeking innovative researchers who aim to address fundamental questions in bio...

staging.ibdm.univ-amu.fr

New work from @antoinedechevigny.bsky.social and colleagues in the team! Fantastic resource for those interested in gene expression dynamics throughout cortical histogenesis and ligand-receptor interactions between cortical neurons. #neuroscience #neuroskyence

Antoine de Chevigny@antoinedechevigny.bsky.social · 2y ago

Delighted to showcase our atlas for the inference of ligand-receptor mediated interactions between neuronal subtypes during mouse cortex development. Herculean endeavor by former PhD student Rémi Mathieu (now @alleninstitute.bsky.social) and team, in collaboration with @LudovicTelley Thread 🧵

Our little update on the latest knowledge on interneuron wiring! www.sciencedirect.com/science/arti...

Dynamic regulation of cortical interneuron wiring

Inhibitory interneurons play crucial roles in modulating the circuits and activity patterns of the cerebral cortex. In particular, interneurons must a…

sciencedirect.com

Would you like to speak at an upcoming Development presents… webinar? We're looking for self-nominations from postdocs – based outside of the US and Europe – looking to transition to an independent position within the next year or so. #DevBio #StemCell #FuturePI @dev-journal.bsky.social

Excited to share the latest work from our lab where we examined the role of pyramidal cells in regulating microglia development! As per tradition here is a graphical summary of our paper in comic form. www.science.org/doi/10.1126/...

Here is the 2025 embryo alphabet from alligator to zebrafish. Developmental biology is stunning & leads to important discoveries for human medicine. @socdevbio.bsky.social