Summer Preprint Alert 🔥🚨 Breathing isn't just for oxygen; it’s a rhythmic pacemaker for the sleeping brain. Our new preprint shows that the respiratory cycle actually gates memory reactivation during NREM sleep! 🧠😴💨 👇🧵(1/8)

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 6d ago

The breathing cycle gates memory reactivation during human NREM sleep https://www.biorxiv.org/content/10.64898/2026.07.29.741474v1

If you are interested in nervous system evolution you may want to read our review with Kei Jokura on nerve nets: "Revisiting nerve nets: functional organization and evolutionary implication" https://link.springer.com/article/10.1038/s44318-026-00879-w […] [Original post on biologists.social]

“Cerebral vasculature shapes the spatial patterning of brain metastases” Note: Systemic metabolic factors should be incorporated into the assessment of patient-level brain metastatic risk. Now available at: www.biorxiv.org/content/10.6...

Our new paper with lead and corresponding author Luis Yañez-Guerra on placozoan monoamine GPCRs and the "Prebilaterian origin of monoaminergic signaling" […] [Original post on biologists.social]

Interested in the principles shaping connectome architecture? See our latest in @cp-cell.bsky.social led by F Normand @nsb-lab.bsky.social A simple model using geometric eigenmodes captures cortical connectomes of different species. Paper: tinyurl.com/3r43spf5 Thread: tinyurl.com/vx74hp6u

Your heartbeat quietly shapes how your brain processes information www.science.org/content/arti...

Your heartbeat quietly shapes how your brain processes information

Frequently ignored bodily rhythms may be skewing neuroscience experiments

science.org

Out now in @pnas.org We present a new metabolism-weighted brain connectome that incorporates each region’s energy expenditure into the mapping of brain connectivity. www.pnas.org/doi/10.1073/...

Researchers have identified superparamagnetic macrophages in the livers of rock pigeons to be crucial for magnetic sensing. The finding uncovers an unexpected role for immune cells in sensory perception and may fundamentally change our understanding of animal navigation. https://scim.ag/4nTQ3nq

Do brain circuits really sit in a 'soup' of neuromodulators? Are neurons like soggy bits of bread soaked in signaling factors? Is the whole brain just squelching around in one big pool of warm modulators?

🚨 The actual paper is now out on @cp-trendscognsci.bsky.social: www.sciencedirect.com/science/arti... In this opinion piece, @duncanastle.bsky.social and I explore the human brain through the lens of optimality and Pareto-optimality theory.

Embracing the suboptimal organization of the human brain

Human brain architecture is guiding brain-inspired artificial intelligence (AI) and has been treated as an optimal template, whose deviations could ma…

sciencedirect.com

Kayson Fakhar@kayson.bsky.social · 4mo ago

For all the esteemed scholars out there who prefer gaining knowledge the correct way, here’s a summary of our upcoming opinion piece, delivered to you by Jesus himself. But seriously, science communication is about to get a lot worse and better at the same time.

Delighted that our paper about benchmarking gene expression 🧬 in macaque brain 🐒🧠(www.science.org/doi/10.1126/...) was selected for this year's Brain Star Award of the Canadian Neuroscience Association 🇨🇦 - what an honour to be named among such talented scientists!

Canadian Association for Neuroscience@canacn.bsky.social · 3mo ago

CAN and CIHR-INMHA are very proud to announce the winners of the 2025 Brain Star awards. See all their profiles here: can-acn.org/congratulati...

Our preprint has grown up, and it is now out in @natneuro.nature.com Bottom line: variable patterns of brain connectivity in #autism can reflect distinct underlying biological mechanisms 🧠🐭 Paper: www.nature.com/articles/s41... Mouse fMRI datasets: tinyurl.com/44dwe6dz Detailed explainer below👇

Autism subtypes identified using cross-species functional connectivity analyses - Nature Neuroscience

Pagani et al. used cross-species fMRI to reveal two autism subtypes, characterized by lower and higher brain connectivity and linked to synaptic and immune-related pathways, respectively.

nature.com

Alessandro Gozzi@gozziale.bsky.social · last yr.

Can we use brain scans to identify biologically distinct "autisms"? And If so, how? In our latest cross-species study 🐭👨 with @iitalk.bsky.social we dive into these questions! Find out more here 👇👇 www.biorxiv.org/content/10.1... Thread below 🧵 1/n

Astrocytes do so much more than any of us thought - they even communicate among specific brain regions across hemispheres! The journey to this paper spanned nearly a decade, but I'm most excited to see what everyone else does with the tools we've built. There's so much for all of us to explore!

Astrocytes connect specific brain regions through plastic networks - Nature

Communication between distant brain regions is mediated by plastic networks of gap junction-coupled astrocytes.

nature.com

Interorgan crosstalk typically occurs via the bloodstream. We showed that brain-heart-gut interplay also occurs in their electrophysiology at infra-slow timescales. We found that fluctuations in the gut are typically followed by the brain and heart after tens of seconds. doi.org/10.64898/202...

Comparative anatomy of brain metabolism in human and macaque (and other species). The dichotomy between glucose as fuel and glucose for tissue building is conserved across species. @moohebatpe.bsky.social and @misicbata.bsky.social www.biorxiv.org/content/10.6...

First off, these cells are gigantic. This one, for example, has >72 cm of axon! To our knowledge, it’s the longest neuron ever fully reconstructed. I leave it to the reader as an exercise to estimate the length of a human LC neuron. 5

Delighted to share our discoveries about one of the brain's neurotransmitter systems: www.biorxiv.org/content/10.6... Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1

Using simulations, we investigated whether Value-Shaping imitation was always a good thing. And it's not (or is it ?? *gasp*) 🧵

Stefano Palminteri@stepalminteri.bsky.social · 4mo ago

📄 New preprint: The blessing and curse of Value-Shaping imitation (by @isabellehoxha.bsky.social) osf.io/preprints/ps... Imitation is central to human learning: but not all imitation processes are equally adaptive. We study their computational properties using reinforcement learning models.

"The Brain, In Theory" is out today! A short excerpt in The Transmitter @thetransmitter.bsky.social www.thetransmitter.org/theoretical-...

‘The Brain, In Theory,’ an excerpt

In his new book, Brette pushes back against theories that describe the brain as a “biological computer.” In this excerpt from Chapter 4, he challenges equating brain evolution with programming…

thetransmitter.org

Wanna do neuroscience in Paris but can't find interesting lab? Want to come do a sabbatical but don't know who to collaborate? Check this webpage aggregating ~all the neuroscience labs (+200) in Paris. ⚠️only the information of 'verified' profiles is reliable⚠️ Please retweet 🙏 parisneuro.fr

Correlating brain maps across datasets is everywhere in neuroimaging. Here we ask: when you contextualize a brain map against genes, metabolism, or connectivity... What can you really conclude? How can we do better? We explore these questions here: tinyurl.com/2dudkevc

Opportunities and pitfalls of data contextualization in neuroimaging - Nature Reviews Neuroscience

Despite rapid exploitation of the opportunities that contextualization of brain maps affords, potential limitations have received little attention. In this Roadmap, Royer et al. provide practical guid...

tinyurl.com

Thrilled to share our new paper, which shows that the relative timing of cholinergic and dopamine release dynamically gates whether dopamine acts as an RPE for in vivo plasticity and reinforcement learning. www.nature.com/articles/s41...

Acetylcholine demixes heterogeneous dopamine signals for learning and moving

Nature Neuroscience - Jang et al. measured dopamine and acetylcholine release in the striatum of rats performing a decision-making task and found that the relative timing of cholinergic and...

nature.com

🧠What if increasing neuronal firing could actually reduce fMRI connectivity? 📡What drives long-range fMRI connectivity? I’m very excited to share that my PhD work is now out as a preprint Check this out! 👇 doi.org/10.64898/202...

Curious about how brain and body communicate, or how circuit states are regulated over seconds to hours? Read our paper about neuropeptide systems and how they contribute to neural architecture and function #neuroskyence #compneuro #neuroscience

Bratislav Misic@misicbata.bsky.social · 5mo ago

Organization of neuropeptide systems in the human brain | doi.org/10.1038/s415... Neuropeptides are functionally diverse signaling molecules in the brain and body. @cebric.bsky.social curates an atlas of neuropeptide receptors and relates it to brain function @natneuro.nature.com 🧩 🧠 ⤵️

Just out in @natneuro.nature.com! 🧠 “Competitive interactions shape mammalian brain network dynamics and computation” www.nature.com/articles/s41... Is large-scale brain communication purely cooperative — or is competition a core organizing principle? We built 🧠 models to find out: read on🧵👇

Competitive interactions shape mammalian brain network dynamics and computation - Nature Neuroscience

Brain network architecture may balance cooperation and competition across circuits. Here the authors use computational whole-brain modeling across three species to show that models with competition ar...

nature.com

Spatial organization of AQP4 channels in the human brain: links with perfusion, edema, and disease vulnerability | doi.org/10.64898/202... Aquaporins are a key component of the brain’s glymphatic system. How are they distributed and how do they relate to healthy brain function and dysfunction? ⤵️

Synaptome architecture shapes regional dynamics in the mouse brain | doi.org/10.1371/jour... How do diverse synapses relate to the spatial patterning of whole-brain dynamics? Justine Hansen explores @plosbiology.org ⤵️

🚀 We are hiring: a PhD position is available in my lab (gozzilab.it) at @iitalk.bsky.social, Italy. Project: large-scale brain network mapping in behaving mice using functional ultrasound imaging (FUSI). 📅 Deadline: March 31 🔗 tinyurl.com/4jtetxa9 Reshares appreciated 😊

Excited to introduce ScaRCaMP — a highly blue-light resistant red GECI. 🔴 Now live on bioRxiv and marking my first PhD preprint (2nd for the Marko lab). Would love feedback from the community!!

Jeff Markowitz@vulcnethologist.bsky.social · 5mo ago

We made a highly blue-light resistant red-fluorescent genetically encoded calcium sensor GECI) www.biorxiv.org/content/10.6... BluePrint™ 🗺️ below:

Excited to share our new paper to be published in Neuron! With Valentin Schmutz @bio-emergent.bsky.social and Wulfram Gerstner @gerstnerlab.bsky.social, we explore how circuit structure in RNNs shapes network computation and single-neuron responses. www.sciencedirect.com/science/arti...

Linking neural manifolds to circuit structure in recurrent networks

Dimensionality reduction methods are widely used in neuroscience to investigate two complementary aspects of neural activity: the distribution of sing…

sciencedirect.com