Eric H Chang

@changsbrain.bsky.social

Neuroscientist | Associate Professor, Feinstein Institutes for Medical Research, Northwell Neuro-immune interactions, vagus nerve, history of medicine, cancer, systems biology, bioelectronic medicine Faculty page: https://tinyurl.com/mrka9nxe

This is addressed to everyone, but especially Americans under the age of 30: Read dystopian novels. Read 1984, and Brave New World, and Fahrenheit 451, and White Noise, and—fuck—even Hunger Games. So many of you just aren’t getting what’s been happening just because you don’t read.

Why are apps and programs forcing AI tools on me? I don't want help writing emails. I don't want summaries of 2 line correspondences. I don't need to lookup the logo from the app I want to use, I just want to open it. Honestly, stop trying to make my life easier because you are doing the opposite.

Heading into May of 2026 and so far this year, no new grants have been issued by the National Institutes of Health, National Eye Institute. No council meetings have been scheduled. An absolute, unmitigated disaster for vision research is setting up.

How it started / how it’s going — Jay Bhattacharya edition. 2025: “We will never use this agency to censor scientists who disagree" 2026 : Bhattacharya “has canceled the publication of a study that found that the Covid vaccine sharply cut the odds of hospitalizations and emergency visits”.


foxandfriends
Follow
"We will never use this agency to censor scientists who disagree": Director Jay Bhattacharya reflects on his pandemic-era censorship experiences & outlines his commitment to open scientific communication at the NIH.
April 1, 2025A Health Department official said Dr. Jay Bhattacharya had met with the study's authors but that they had not wanted to change its design. Eric Lee for The New York Times
By Apoorva Mandavilli
April 22, 2026
The acting head of the Centers for Disease Control and Prevention has canceled the publication of a study that found jthat the Covid vaccine sharply cut the odds of hospitalizations and emergency visits last winter, a Health Department spokesman said.

To my non tech normies, PSA: when you share a link, everything after the ? is tracking. Those “query parameters” tell companies exactly how you arrived, what app you clicked, which ad or email sent you, sometimes a unique identifier tied to you. You can delete everything after the question mark.

Benefits from DEI: NASA’s first crewed mission around the Moon in 50+ years included… ✅Christina Koch (first woman on a lunar mission) ✅Victor Glover (first Black astronaut on a lunar mission) ✅Reid Wiseman (single Dad) ✅Jeremy Hansen (first Canadian headed to the Moon). Not “woke,” PROGRESS.👇

Bild

🥁🎉The Psychosis Collective proudly presents our first preprint 𝐂𝐥𝐨𝐳𝐚𝐩𝐢𝐧𝐞 𝐬𝐮𝐩𝐩𝐫𝐞𝐬𝐬𝐞𝐬 𝐚𝐮𝐭𝐨𝐢𝐦𝐦𝐮𝐧𝐢𝐭𝐲 𝐝𝐫𝐢𝐯𝐢𝐧𝐠 𝐩𝐬𝐲𝐜𝐡𝐨𝐬𝐢𝐬-𝐥𝐢𝐤𝐞 𝐛𝐞𝐡𝐚𝐯𝐢𝐨𝐮𝐫 𝐢𝐧 𝐦𝐢𝐜𝐞 𝘈 𝘥𝘪𝘴𝘤𝘰𝘷𝘦𝘳𝘺 𝘫𝘰𝘶𝘳𝘯𝘦𝘺 𝘪𝘯 𝘵𝘩𝘳𝘦𝘦 𝘢𝘤𝘵𝘴 starring Le He & Harriet Feldman www.biorxiv.org/content/10.6... We wanted to understand how antipsychotics work. Thread🧵

Graphical abstract showing that NMDAR immunisation drives psychosis-like behaviour in mice, while clozapine reverses this. Upper panel: arrows show NMDAR immunisation producing a mouse exhibiting psychosis-like behaviour, with clozapine reversing this effect. Lower panels: anti-NMDAR antibodies bind neuronal NMDA receptors, which are then eliminated by microglia via phagocytosis, leading to psychosis. Clozapine restores NMDA receptor levels by reducing anti-NMDAR antibody levels, consistent with an immunomodulatory mechanism of action.